ライフサイエンスコーパス: lactate dehydrogenase A

1 a targets VEGF-A, glucose transporter-1, and lactate dehydrogenase A.

2 (HIF-1) in the transcriptional activation of lactate dehydrogenase A, aldolase-A, phosphoglycerate ki

3 lpha including those involved in glycolysis (lactate dehydrogenase A and enolase 2), oxidant stress (

4 rast, genes barely expressed in sham islets (lactate dehydrogenase A and hexokinase I) were markedly

5 Myc oncogenic transcription factor regulates lactate dehydrogenase A and induces lactate overproducti

6 to the hypoxia response element site in the lactate dehydrogenase A and PKM2 loci and mediates the r

7 Hexokinase-I, GLUT3, and lactate dehydrogenase-A and -B were ubiquitous, whereas

8 nown biomarkers of acidity, such as hypoxia, lactate dehydrogenase A, and CAIX.

9 Small interfering RNA ablation of lactate dehydrogenase A attenuated HDM-induced increases

10 /fructose-2,6-bisphosphatase-3 (PFKFB3), and lactate dehydrogenase-A expression.

11 er HIF-1-regulated promoter derived from the lactate dehydrogenase A gene.

12 The lactate dehydrogenase-A gene (LDH-A), whose product part

13 , including those for the glycolytic enzymes lactate dehydrogenase A, hexokinase II, and 6-phosphofru

14 s normally suppressed in beta-cells, such as lactate dehydrogenase-A, hexokinase I, glucose-6-phospha

15 xpression of glycolysis-regulating molecules lactate dehydrogenase A (LDH-A) and heat shock factor 1

16 Lactate dehydrogenase A (LDH-A) catalyzes the interconve

17 The lactate dehydrogenase A (LDH-A) gene, whose product part

18 regulation of heat shock factor 1 (HSF1) and lactate dehydrogenase A (LDH-A) in ErbB2-positive cancer

19 r basis of the cAMP-induced stabilization of lactate dehydrogenase A (LDH-A) mRNA and identified four

20 ces, the multiprotein complex binding to the lactate dehydrogenase A (LDH-A) promoter was characteriz

21 Lactate dehydrogenase A (LDH-A) regulates the last step

22 ation of c-Myc target genes, such as rcl and lactate dehydrogenase A (LDH-A), is critical for underst

23 Orthologous homologs of lactate dehydrogenase-A (LDH-A) (EC 1.1.1.27; NAD+:lacta

24 ed the contributions of macrophage-expressed lactate dehydrogenase-A (LDH-A) to tumor formation in a

25 es barely expressed in sham islets including lactate dehydrogenase-A (LDH-A), lactate (monocarboxylat

26 Lactate dehydrogenase-A (LDH-A), responsible for convers

27 ntially metabolized to lactate by the enzyme lactate dehydrogenase-A (LDH-A), suggesting a possible v

28 of the genes encoding hexokinase 1 (HK1) and lactate dehydrogenase A (LDHA) - both of which regulate

29 Lactate dehydrogenase A (LDHA) catalyzes the conversion

30 ing hematopoietic stem cells (HSCs), whereas lactate dehydrogenase A (LDHA) deletion significantly in

31 Lactate dehydrogenase A (LDHA) has been reported to be i

32 Here, we show that lactate dehydrogenase A (LDHA) is induced in activated T

33 ate Kinase 1 (PGK1), Hexokinase 2 (HK2), and Lactate Dehydrogenase A (LDHA) were each significantly h

34 t that phosphorylation-induced activation of lactate dehydrogenase A (LDHA), an enzyme that catalyses

35 housekeeping genes - such as those encoding lactate dehydrogenase A (LDHA), solute transporter MCT1,

36 take up glucose and generate lactate through lactate dehydrogenase A (LDHA), which is encoded by a ta

37 f pyruvate dehydrogenase kinase 1 (PDK1) and lactate dehydrogenase A (LDHA).

38 rpin RNA against GBP-5) release twofold less lactate dehydrogenase (a marker of membrane permeability

39 enase, a marker of lipolytic metabolism; and lactate dehydrogenase, a marker of glycolytic metabolism

40 ycolytic enzymes, with notable expression of lactate dehydrogenase A occurring in the airway epitheli

41 Expression of the lactate dehydrogenase A subunit (LDH-A) gene can be cont

42 Expression of the lactate dehydrogenase A subunit (ldh-A) gene is controll

43 re, we show that pharmacologic inhibition of lactate dehydrogenase-A suppressed the conversion of hyp

44 genes driving aerobic glycolysis, including lactate dehydrogenase-A that generates lactate.

45 is enzymes pyruvate dehydrogenase kinase and lactate dehydrogenase A within cortical and hippocampal