ライフサイエンスコーパス: lag time

1 t associated with UFP, AMP, and PM2.5 at any lag time.

2 f amyloid without significantly reducing the lag time.

3 pulation reaches a maximum at the end of the lag time.

4 r on the mean and variance of the population lag time.

5 0% conversion occurring much faster than the lag time.

6 ns is sufficient to reduce or eliminate this lag time.

7 dominant molecular mechanism determining the lag time.

8 tion which always displayed a characteristic lag time.

9 o be detected and quantified even during the lag time.

10 ratio, as well as significantly reducing the lag time.

11 ated to changes in light intensity with a 3h lag time.

12 arameters of the distribution of single cell lag times.

13 luence of neighboring cells, and diffusional lag times.

14 r source of noise that appears at very large lag times.

15 dihydrate (TMAO) and sucrose, increased the lag times.

16 effect of kinetic inhibitors on fibrillation lag times.

17 pecies increased with precipitation at short lag times (1-1.5 years) likely due to enhanced food avai

18 fter periods of high precipitation at longer lag times (2-4 years) likely due to predation and other

19 lly appropriate settings for the (1) minimum lag time, (2) maximum lag time, and (3) averaging times

20 After a short lag-time, 4,6-dinitroguaiacol is also formed.

21 A very short lag time (5.4 s) for [(14)C]acetate labeling of PC impli

22 dienes: 485 +/- 55 micro mol/mg LDL protein; lag time: 51.7 +/- 15.9 min; and rate of oxidation: 25.4

23 In fact, a longer lag time (60 h) was observed in YlPMR1-defective mutant

24 The reduction in this lag time accounts for the relative selectivity of the ef

25 id bound cspA1/A2 dramatically increases the lag time after a cold shock before re-growth occurs.

26 ssful only do so (i) after an unusually long lag time after initial arrival, and/or (ii) after multip

27 With appropriate lag time after NF-kappa B binding, COX-2 mRNA and protei

28 Nucleation rates (lag time) also correlated with bead mass, but only for n

29 ove significant associations remained in the lag time analyses, applied to check for reverse causatio

30 ccurred via a dose-dependent decrease in the lag time and an increase in the fibrillization rate, con

31 The addition of ANS increased the lag time and decreased the apparent growth rate for insu

32 fibrillization, significantly increasing the lag time and decreasing the total amount of fibrils prod

33 fibril formation by reducing the nucleation lag time and diminished protein thermodynamic stability.

34 s formed fibrils in vitro, Wil had a shorter lag time and exhibited faster kinetics under physiologic

35 TGFbeta induced hypermotility after a 1-day lag time and growth arrest by a p16-independent mechanis

36 y are capable of increasing the fibrillation lag time and high levels of crowder hydrophobicity can f

37 ed evolved strains which exhibited a shorter lag time and improved xylose-fermenting capabilities tha

38 nes with viral E1 and template shortened the lag time and increased replication in a cell-free system

39 chemical carcinogenesis, CD151 reduces tumor lag time and increases incidence, multiplicity, size and

40 kinetics of self-association, decreasing the lag time and leading to insoluble, well-defined linear f

41 onse to collagen, they did so with prolonged lag time and lessened intensity.

42 ntrations, BbetaA68T fibrinogen had a longer lag time and lower rate of lateral aggregation, V(max),

43 Lag time and maximum growth rate were determined from co

44 correlations are calculated as a function of lag time and phase.

45 2522 and clinical characteristics, including lag time and pre-enucleation treatment status.

46 half-life of the drug and the stage-specific lag time and provides the framework for understanding th

47 entation with fish oil and placebo shortened lag time and slowed propagation rate in women both using

48 ed in clotting curves with 3-9 times shorter lag time and steeper slopes with respect to H2O.

49 e and kidney stone presentation according to lag time and temperatures.

50 r interactions in defining the length of the lag time and the apparent rate of elongation of the 100-

51 t of the mean and variance of the individual lag time and the initial cell number on the mean and var

52 ase, BbetaA68T fibrinogen polymerized with a lag time and V(max) similar to normal, but reached a sig

53 otyls was induced by Cel12A after a distinct lag time and was accompanied by a large increase in wall

54 rotein state equilibria can alter nucleation lag time and, hence, fibril formation kinetics.

55 ed during amyloid fibril formation shortened lag times and caused pressure insensitivity of nucleatio

56 Shorter lag times and faster growth of fibrils were seen at acid

57 in insulin concentration resulted in shorter lag times and faster growth of fibrils.

58 lin concentration and ionic strength on both lag times and fibril growth.

59 il morphologies and produce eightfold faster lag times and fourfold less stochasticity than in previo

60 treatment with SPHase resulted in shortened lag times and increased rates of oxidation in both LDL s

61 t extract (10 mg/L) was critical to diminish lag times and increased the biotransformation rate of NT

62 Sensitivity analysis using different lag times and kernel density bandwidths were tested to e

63 Proton inventories of inverse lag times and maximal slopes of blood clotting curves in

64 t isotope effects (SIEs) result from inverse lag times and maximal slopes of blood clotting plots, wh

65 rated tau nucleation as reflected by shorter lag times and modulated pre-nuclear equilibria to yield

66 The observed lag times and multiple introductions that seem a prerequ

67 otein oxidation in vitro, which has abnormal lag times and propagation rates for subjects with NIDDM

68 n a narrower distribution of the aggregation lag times and rates.

69 assembly process is "downhill" despite clear lag times and significant concentration dependence.

70 crease in ionic strength resulted in shorter lag times and slower growth of fibrils.

71 The intestinal permeation studies showed a lag-time and apparent permeability coefficient that were

72 gs for the (1) minimum lag time, (2) maximum lag time, and (3) averaging times over which an autocorr

73 thrombin potential, the peak height, and the lag time, and replicated the main findings in 2 independ

74 posure to drug, cell death commences after a lag time, and the cell kill rate is dependent on the amo

75 nce, there is a so-called surface-associated lag time, and the organisms then enter a growth phase an

76 ons for the size of the critical capsid, the lag time, and the steady-state nucleation rate of capsid

77 rence and in any summary statistics, such as lag times, and allows interpolation with the correspondi

78 usly by using a recently developed automated lag-time apparatus (ALTA).

79 nding to a multilayer geometry; the flux and lag time are affected when the lipid transbilayer diffus

80 pendent differences in predicted aggregation lag times are in the same range as the length-dependent

81 of the process(es) that occur(s) during the lag time arises at a later step and involves a minimum o

82 alyte showed that the device could achieve a lag time as small as 14 s.

83 t be bounded by adequate minimum and maximum lag times as dictated by the fast and slow diffusing spe

84 uclein at low micromolar concentrations with lag times as short as 11 min and apparent first order gr

85 mineral apposition rate, and mineralization lag time, as well as higher osteoid surface, osteoblasti

86 ctivation at pH 3; however, growth rates and lag times at 43 degrees C and at pH 4.5 were not affecte

87 y decreasing the otherwise long fibrillation lag times at low pH and accelerates fibril growth rates

88 pherol contents significantly and lengthened lag time (at even the lowest concentration) but had no s

89 n concentration and mutations on the initial lag time before amyloid fibrils form in the protein solu

90 ns: incomplete symptom relief and 2-3 months lag time before clinically meaningful improvement.

91 undles can form prior to fusion and that the lag time before fusion occurs may include the time neede

92 ound with acid capped PLGA but with a longer lag time before release.

93 s may have low migration capacities and long lag times before colonization of new areas.

94 pores' GR-dependent germination had a longer lag time between addition of germinants and initiation o

95 some target cell types, (2) determining the lag time between cholera toxin binding and the target ce

96 The timing of commitment and the lag time between commitment and DPA release were also de

97 ll body contraction led to a decrease of the lag time between force generation and FA growth, indicat

98 el to sample injection, resulting in minimum lag time between injections.

99 en two loci can be identified by varying the lag time between locus position measurements.

100 The physical lag time between microdialysis and the analytical signal

101 characteristics--such as size of commitment, lag time between signature and first disbursement, and f

102 sporine, and XIAP overexpression reduces the lag time between the administration of an apoptotic stim

103 blots after 6 h of Al exposure, indicating a lag time between the Al-induced WAK transcription and tr

104 true equivalence flow rate FE because of the lag time between the first compositional change and its

105 apoptosis, yet resulted in a decrease in the lag time between treatment of the cells and the inductio

106 l center (GC) reactions; however, there is a lag time between vaccination and the generation of GC B

107 We found that the lag times between acidification and fusion were signific

108 tions were strongest for cases with shortest lag times between blood draw and diagnosis (<3 years).

109 For spore populations, the lag times between commitment and DPA release were increa

110 the times needed for commitment, as well as lag times between commitment and DPA release.

111 lysis of the distributions of loop sizes and lag times between loops reveals that initiation of prime

112 exposure classifications to model differing lag times between NSAID exposure and cancer development.

113 f BMI with survival was stronger with longer lag times between reported BMI and cancer diagnosis.

114 d a bimodal distribution of peak correlation lag times between spiking activity and force, whereas SI

115 There are also major lag times between when these clades colonized the region

116 mplicated by nonlinearities, feedback loops, lag times, buffering and convergence among processes wit

117 of age, sex, lymphoma diagnosis-to-treatment lag time, calendar year, International Prognostic Index

118 ted in a concentration-dependent decrease in lag time consistent with each peroxide's ability to act

119 were observed, but only for polymeric beads: lag times correlated negatively with contact angle of wa

120 type I and triplex sites was shortened, the lag time decreased whilst the displacement reaction rema

121 on intracellular subdiffusion and elucidate lag-time dependence, with particular focus on the impact

122 cted as a 20- to 60-min decrease in splicing lag time depending on the pre-mRNA substrate.

123 We derived the individual lag time distribution inherent in population growth mode

124 allows a wide range of shapes for individual lag time distribution.

125 hrough a major adjustment in the single-cell lag-time distribution, without a change in resistance.

126 We demonstrate that individual cell lag time distributions cannot be retrieved from populati

127 only growth phenotype observed was a longer lag time during growth on nonfermentable carbon sources

128 The factors that govern fibrillation lag times during kinetic inhibition are largely unknown,

129 sigmoidal kinetic profile and showed shorter lag times during seeding with preformed amyloid fibrils

130 ion mechanism characterized by a significant lag time, during which the peptide is monomeric, and tha

131 Better understanding of lag-time evolution as a key determinant of the survival

132 oordination of copper to HTI showed a 6-8 ms lag time followed by a k(obsII) of 121 +/- 9 s(-)(1).

133 rate coefficients, and introducing a 100 day lag time for acetoclastic methanogenesis for oleate and

134 or 4 (PF4) binds to bacteria and reduces the lag time for aggregation, and gray platelet syndrome alp

135 rage intracellular drug concentration, and a lag time for cell killing.

136 fer-acquired LOOHs significantly reduced the lag time for chain initiation relative to that observed

137 /- 50 ng/L, respectively; P = 0.028) and the lag time for copper-ion-induced LDL oxidation was longer

138 etheneotrophs exhibit significantly reduced lag time for ethene utilization when epoxyethane is adde

139 xtures with normal collagen II increased the lag time for fibril assembly and altered the morphology

140 The marked increase in the lag time for fibril formation with mutations to more pol

141 ermodynamic stability and an increase in the lag time for fibril formation.

142 brillation process could be described by the lag time for formation of stable nuclei (nucleation) and

143 e of the initial half-time, t1/2 (sum of the lag time for formation of the first intermediate, IM1, p

144 The lag time for gastric emptying was prolonged in 2 patient

145 nt 22% lower than that to gammaA-Fn, and the lag time for initiation of Pg activation by tPA was long

146 Lag time for LDL oxidation increased 32% at 12 weeks, su

147 Lag time for oxidation of unfractionated plasma and plas

148 usion times for experimental conditions if a lag time for platelet activation is included.

149 ing inert polymers significantly reduced the lag time for protofibril formation and the conversion of

150 Under the experimental conditions, the lag time for the formation of precipitable aggregates is

151 say is transient, causing a reduction in the lag time for the translational expression of the newly s

152 Unlike strand opening, we did not observe lag times for G-ladder synthesis.

153 Lag times for LDL oxidation were prolonged during the tr

154 including low response rates and substantial lag times for response.

155 ics, emerging antiviral resistance, and long lag times for vaccine development, raising a pressing ne

156 factors such as a decrease in the transient (lag) time for appearance of the final product of the cou

157 (vii) T(lag) times for spoVA(1) and spoVA(2) spores were longer

158 t on hIAPP fibrillogenesis: it increases the lag-time for fiber formation and decreases the rate of a

159 obes, leading to the development of a novel, lag time-free quantitative assay to evaluate the activit

160 resection data, there appears to be a 5-year lag time from IPMN adenoma (63.2 years) to invasive canc

161 methodology to better estimate fibrillation lag times from experimental curves.

162 rse the skin tissue into the receptor fluid (lag time) from 0.25 h for BDE-1 to 1.26 h for BDE-153.

163 s effect was significant for patients with a lag time >1 month and no pre-enucleation treatment (P =

164 t a main effect of BRICHOS is to prolong the lag time in a concentration-dependent, quantitative, and

165 E added to such seeded reactions extends the lag time in a dose-dependent manner, so that higher leve

166 sterol in 18:0,18:1PC induced a considerable lag time in MII-G(t) formation after MII formed.

167 IgG1 added to IgG-depleted PRP increased the lag time in response to 5B9.

168 Our data show that during the lag time in sedimentation kinetics, there is substantial

169 for the molecular basis of the 60- to 90-min lag time in the interaction of Neisseria gonorrhoeae car

170 Higher cloning, reduced lag time in tissue, and the acquisition of growth factor

171 A comparison of the lag times in the approach to the steady-state rate of ab

172 After ingestion of grape juice, lag time increased by 34.5% (P=0.015).

173 hly unusual kinetics are observed, where the lag time increases with increasing peptide concentration

174 The exosomes reduce the lag time indicating that they provide catalytic environm

175 ized by concentration-dependent decreases in lag time, indicating increased nucleation rates, and sub

176 the total filament length without modulating lag time, indicating that filament extension but not nuc

177 lament mass were not associated with reduced lag times, indicating that these posttranslational modif

178 In general, this theory predicts that as the lag time interval increases, the dual-loci dynamic behav

179 survival by grouping reported BMI by 2-year lag-time intervals before diagnosis.

180 ies are present at early stages and that the lag time is defined by the primary nucleation rate only.

181 n single cells in real time to determine the lag times leading to the formation of the first function

182 itions do not permit achieving the necessary lag time limits for both of the species in a binary syst

183 y one specimen of the 231 analyzed to have a lag time longer than 6 y.

184 sensors were characterized by shorter sensor lag times (<4.2 min) in response to intravenous glucose

185 milar cholesterol levels, LDL oxidizability (lag time, malondialdehyde, and relative electrophoretic

186 Similar evolutionary lag times may occur in other organisms and habitats, but

187 the whole-genome duplication (WGD) radiation lag-time model, which postulates that increases in diver

188 nt statistical support for the WGD radiation lag-time model.

189 of chloride channel function by reducing the lag time necessary for channel activation and consequent

190 achieved averaged 1.22 hours with an average lag time of 0.22 hours after oral administration.

191 In contrast, a lag time of 1-2 h occurred before abscisic acid accumula

192 detected before RNFL thinning, with a median lag time of 15.8 months (range, 4.0-40.8 months).

193 ious estimates of epidermal turnover, with a lag time of 18 days before label appeared at the skin su

194 conversion was 660 microliters with a median lag time of 212 days and 137 days for seroconversion and

195 Munc18-c traffic was time-dependent with a lag time of 3 min compared with GLUT4.

196 rage energy and macronutrient intakes with a lag time of 3-4 d, but not 1-2 d.

197 in Arabidopsis, as in other species, after a lag time of 30 s.

198 opper-induced lipid peroxidation exhibited a lag time of 4 h, while peroxide-induced lipid peroxidati

199 saturation at 120 min, and was preceded by a lag time of 40 min.

200 We model the lag time of a single cell, inoculated into a new environ

201 t to induce apoptosis, which occurred with a lag time of about 24 h, although longer treatments produ

202 relationship between protein solubility and lag time of amyloid formation is not captured by current

203 bility in determining amyloid propensity and lag time of amyloid formation, highlighting how small di

204 ter understand the role of solubility on the lag time of amyloid formation.

205 is immediate, the action of cPLA2 requires a lag time of approximately 12-15 min, probably the time n

206 correlated with Ca(2+)i oscillations with a lag time of approximately 5-6 s.

207 After a lag time of around 10 h, a phase transition occurred in

208 highly fluctuating semistable stages, and a lag time of at least several seconds between the trigger

209 Strikingly, we found that the lag time of bacteria before regrowth was optimized to ma

210 ustment for age, lag time of seroconversion, lag time of CD4 cell measurement, risk group, and clinic

211 is located in the lipid layers; the flux and lag time of diffusion through a brick-and-mortar geometr

212 In the spontaneous reactions, the lag time of fibril formation was rather uniform for the

213 addition of 0.3% mucin to BHI-HS reduced the lag time of H. pylori by 48 h and enhanced the growth.

214 data lead to absolute quantification of the lag time of mRNA induction (the time it takes for extern

215 here the rate of plasmid growth includes the lag time of newly formed F(+) transconjugants and the re

216 ch velocities of order km/day, and confirm a lag time of order 5-10 days between mound formation and

217 s found to inhibit the rate and increase the lag time of oxidation to a greater extent than the forme

218 initial CD4 level after adjustment for age, lag time of seroconversion, lag time of CD4 cell measure

219 Looking at cell populations, the rate and lag time of the Bid-induced permeabilization are dose-de

220 ing enzymes for optimal kinetic response and lag time of the reporter system, based on the kinetic ch

221 ces lasting up to a minute, and have typical lag times of < 1 s.

222 Lag times of 37 days (sulfate amended) to more than 100

223 sk Assessment, it is vital to understand how lag times of individual cells are distributed over a bac

224 onential growth, and the distribution of the lag times of individual cells.

225 f CD and malondialdehyde, and lengthened the lag times of LDL, sd-LDL and lb-LDL in the order TQ>LMN.

226 Lag times of onset are short and the maximum anesthetic

227 ial response lag times with rings exhibiting lag times of up to 4 h.

228 (iii) The long T(lag) times of gerD spores were partially due to slow com

229 cal/mol), (ii) delays onset of fibrillation (lag time on gentle agitation at 37 degrees C was prolong

230 rations varying from 100 to 0.25 pM with the lag time or initiation phase of thrombin generation incr

231 Users with longer lag times or whose cases are never reported are excluded

232 ical absorbance capacity (P < 0.001) and LDL lag time (P < 0.001) and significantly decreased the LDL

233 ct on the early oligomerization steps in the lag time period.

234 However, the dependence of the lag time preceding the onset of fusion on HA surface den

235 For each cell line we measured the lag time preceding the onset of fusion, the initial rate

236 least two mechanisms are at play during the lag time: primary nucleation and autocatalytic growth.

237 n the C-terminal charge of alpha-syn and the lag time prior to the observation of fibril formation, w

238 ive modification was assessed by calculating lag time, propagation rate, and maximum production of co

239 was positively correlated with LDL oxidation lag time (r = 0.32, P = 0.03).

240 Probabilistic modeling of these lag times revealed that one slow and seven equally fast

241 nstrates that care is needed in interpreting lag-time scaling exponents from protein assembly data.

242 Moreover, we suggest that the "lag time" seen in these studies is not the time needed f

243 displayed a concentration-dependent apparent lag time similar to observations of protein aggregation

244 n were significantly impaired, with a longer lag time, slower rate of lateral aggregation, and decrea

245 ays respond to RET activation with different lag times, such that the balance of signal flux among th

246 pores in populations was the highly variable lag time, T(lag), between mixing spores with nutrient ge

247 s of urea: We determine how the fibrillation lag time (tau(lag)) and maximum growth rate (nu(max)) de

248 In the presence of an antioxidant, the lag time (tau) produced during free radical-induced ster

249 was nucleation-dependent, occurring after a lag time that decreased with increasing peptide concentr

250 nd serotype B cells showed a decrease in the lag time that occurred before the onset of rapid accumul

251 ons enter cells, but it has no effect on the lag time that precedes this entry flow.

252 bited growth rates, final growth yields, and lag times that were significantly reduced compared with

253 In sensitivity analysis, with longer polyp lag times the mean extension in life expectancy decrease

254 is process was inhibited and occurred with a lag time, the duration of which depended on the concentr

255 For an assumed 2-min lag time, the sensor readings were well correlated with

256 e we demonstrate the concept of evolutionary lag time, the time between when a climatic regime or hab

257 In particular, the lag time--the quiescent period before aggregates are det

258 wareness in the CSE tradition, or resumption lag (time to resume an interrupted task) in the applied

259 rations too low to inactivate Ras reduce the lag time to Ag-induced Ca2+ stores release and enhance s

260 idogenesis is observed as an increase in the lag time to amyloid formation and a diminished thioflavi

261 s to enhanced turnover of SECURIN, decreased lag time to anaphase and defects in chromosome segregati

262 yses of baseline consumption, with a 10-year lag time to disease follow-up (quintile 5 vs. quintile 1

263 Considering the lag time to incorporate atmospheric (14)C into plant foo

264 There was a significant reduction in mean lag time to initial symptom perception and an increase i

265 t not antibodies to p110alpha, lengthens the lag time to release of Ca2+ stores and blunts the sustai

266 , or R92E gp91(phox) along with an increased lag time to the maximal rates of superoxide production r

267 stment for significant covariates of age and lag time to therapy (odds ratio [OR] = 0.018, 95% confid

268 mers in an inactive conformation, leading to lag times up to more than 1 h.

269 ack blood glucose with an approximate 30 min lag time, using disposable and colorless contact lenses.

270 rosomucoid, as a novel locus associated with lag time variability, reflecting the initiation process

271 The lag time varied inversely with the enzyme concentration,

272 models fail to explain detailed features of lag time versus concentration curves, suggesting that ne

273 Here we show that experimental data for lag time versus protein concentration can show signs of

274 etic analysis of the data for the reciprocal lag time vs HA surface density, by both a log/log plot a

275 LDL oxidation lag time was approximately 8% greater (P = 0.01) after t

276 d with platelet-rich plasma (PRP), a shorter lag time was measured in 131RR donors compared to indivi

277 rate of aggregation was increased, while the lag time was unaffected.

278 , which is based on matrix analysis of burst lag times, was evaluated using baculovirus samples that

279 ies and landscapes, and indirect effects and lag times, we see a distinct shift away from single-poin

280 relations for epinephrine, ADP, and collagen lag time were 0.24, 0.22, and 0.31, respectively (P=0.00

281 e biphasic platelet aggregation and collagen lag time were determined.

282 These lag times were also decreased dramatically by the action

283 (ii) T(lag) times were lower for upward arrowSpoVA spores than

284 ered strain, however, still exhibited a long lag time when metabolizing xylose above 10 g/l as a sole

285 paired mRNA export and also generated longer lag times when glucose or raffinose was replaced by gala

286 , all mutants displayed significantly longer lag times when switching from growth on trimethylamine t

287 The denaturant, urea, decreased the lag time, whereas the stabilizers, trimethylamine N-oxid

288 ar hospitalizations were highest for smaller lag times, whereas effect estimates for respiratory hosp

289 time to the onset of amyloid formation, (the lag time), while having modest effects on the total amou

290 An increase in lag time with decreasing ATP concentration is also obser

291 inhibitors, which have primarily shifted the lag time with little effect on later stages of aggregati

292 easonal variability, and an increase in peak lag times with increasing body size.

293 ug sensitivity reflect differential response lag times with rings exhibiting lag times of up to 4 h.

294 ncreases in UFP, AMP, and PM2.5 at 1 or more lag times within the previous 5 days.