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1 CR) alpha and beta chains and immunoglobulin lambda chain.
2 than normal IgG and selectively modified the lambda chains.
3 he pre-B-cell-specific marker immunoglobulin lambda chain 5, and contain immunoglobulin heavy-chain r
4 th PPS-6B and PPS-14 Abs expressed kappa and lambda chains, although 6B Abs more frequently expressed
5 tutions (97 in the heavy chain and 13 in the lambda-chain) and only 2 deletions and targeted V(D)J, v
6 ridisation and sequencing we found that most lambda chains are derived from the cluster of V(lambda)
8 ound that in both germ-line heavy chains and lambda chains, CDR codons are prone to replacement mutat
14 rence between CDR and FW in heavy chains and lambda chains is based on codons that are prone to nonco
15 s, although 6B Abs more frequently expressed lambda chains lambda and 14 Abs more frequently expresse
16 ations at the immunoglobulin heavy chain and lambda chain loci than do heterozygotes or wild-type QM
17 noglobulin (Ig) heavy (mu) and light (kappa, lambda) chain loci and is dependent on transient express
18 yzing a mouse mutant in which immunoglobulin lambda-chain-positive B cells are generated in the absen
20 mice had a lower frequency of immunoglobulin lambda-chain-positive B cells in the peripheral blood an
21 mutations, 1470 H chain and 1313 kappa- and lambda-chain rearrangements from three AICDA(-/-) patien
22 gly influence the shaping of the human fetal lambda-chain repertoire that are less evident in the adu
23 tant mice also made fewer B cells expressing lambda chain, whereas lambda versus kappa isotype exclus
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