ライフサイエンスコーパス: laminar

1 These patterns of collective local and laminar activation during behavior were reactivated in c

2 Furthermore, analysis of laminar activation profiles revealed that although atten

3 Recently, it has become possible to measure laminar activity in humans with high-resolution function

4 We found that, due to the laminar aerosol flow and a specific orientation of inver

5 had a pathogenic impact on projection neuron laminar allocation by reducing protein expression.

6 spiration-induced oscillations have a unique laminar amplitude profile, are resistant to atropine, co

7 hybridization to assess Zif268 expression at laminar and cellular levels of resolution.

8 pregulated in subjects with schizophrenia in laminar and cellular samples.

9 ns are distinguished by the pattern of their laminar and columnar inputs from within A1 and their loc

10 Disruption of the laminar and columnar organization of the brain is implic

11 g grid and directional firing fields, have a laminar and dorsoventral organization that corresponds t

12 neighboring brain structures and reveals its laminar and dorsoventral organization.

13 endothelial cells under oscillatory, normal laminar and elevated laminar shear stress for a period o

14 cal descriptions of L4B circuits in both the laminar and functional compartments targeted by their ax

15 uped and segmented through synergistic inter-laminar and inter-areal processes that are dynamically a

16 esults suggest that a gap junction-dependent laminar and retinal glial network transports histamine m

17 We performed a comparative analysis of the laminar and subcellular expression profile of GLAST and

18 Fundamental features of the laminar and topographic distribution of these pathways a

19 It consists of orthogonal laminar and vertical excitatory synaptic connections.

20 Laminar- and target-specific differences of BLA inputs l

21 study, we found focal disruption of cortical laminar architecture in the cortexes of a majority of yo

22 cal/immunohistochemical markers for cortical laminar architecture, mammalian target of (mTOR) pathway

23 lso targeted to specific positions along the laminar axis of the tectum.

24 al nerve fiber layer and the myelinated post-laminar axons, as well as olygodendrocytes and astrocyte

25 a variety of different states competing with laminar background flow.

26 y role in mediating the protective effect of laminar blood flow and suggest that Grx1 may be a potent

27 ess are up-regulated by the anti-atherogenic laminar blood flow often seen in straight or unbranched

28 y results from their distinct margination in laminar blood flow, which opens up a new path for precis

29 While laminar blood flows are known to maintain endothelial ho

30 ctile development of human stem cell-derived laminar cardiac tissues over four weeks.

31 at guide the self-assembly of physio-mimetic laminar cardiac tissues.

32 Our technique is well suited to identify laminar characteristics of fiber tract orientation withi

33 ss cortical layers or whether it engages the laminar circuit in specific and selective ways.

34 upplementary eye field, exhibits features of laminar circuitry similar to those observed in primary s

35 ive single-cell trapping and treatment using laminar co-flow.

36 to distinct GABAergic populations, including laminar cohorts.

37 , and a method to manufacture unidirectional laminar collagen I scaffolds.

38 We use hierarchical clustering on the laminar connection patterns to reveal the existence of m

39 At distances greater than 100 mum, the laminar connections generate a strongly connected direct

40 t of both excitatory and inhibitory synaptic laminar connections to excitatory cells at single cell r

41 t of both excitatory and inhibitory synaptic laminar connections to excitatory neurons in layers 2/3-

42 to look for evidence of local clustering and laminar consistency of linear and angular velocity encod

43 Thick fragments of laminar crustacean cuticle are scattered within the copr

44 events should be associated with a specific laminar current profile.

45 We observed focal patches of abnormal laminar cytoarchitecture and cortical disorganization of

46 n spectral-domain OCT included a thick basal laminar deposit.

47 n the RPE and the thickness of sub-RPE basal laminar deposit.

48 GA and CNV revealed a rippled layer of basal laminar deposits in an area of RPE atrophy that was loca

49 Thick basal laminar deposits may appear hyporeflective on spectral-d

50 s: (1) retinal pigment epithelium, (2) basal laminar deposits, (3) fibrovascular membrane, (4) fibroc

51 correspond to histological findings of basal laminar deposits, extracellular deposits that persist in

52 b-RPE) deposit formation, specifically basal laminar deposits, following high-fat diet.

53 ns, no lipid-filled cells, and thinner basal laminar deposits.

54 The occurrences of significant change in laminar depth and neuroretinal parameters were compared

55 Longitudinal changes in laminar depth and neuroretinal parameters.

56 Anterior laminar depth from a Bruch's membrane (LD-BM) or anterio

57 Factors related to laminar depth were determined with mixed-effects modelin

58 ffect on neuroretinal parameters, but not on laminar depth, changes in neuroretinal parameters were a

59 be used as a reference plane when measuring laminar depth.

60 0 in the peripheral retina would overlap OPL laminar development in outer retina.

61 Laminar development of both IPL and OPL occurred before

62 tion and distal growth of floral organs, and laminar development of leaflets.

63 y be concomitant with abnormal cell type and laminar development.

64 A structural model relates connections to laminar differences between linked areas.

65 bandwidth than L3 cells, consistent with the laminar differences in columnar integration.

66 Similar to their laminar differences in local input, VIP+ neurons receive

67 Such cell-type and laminar differences in neuronal functional properties ma

68 rons provide excitation in both columnar and laminar dimensions, which is modulated further by inhibi

69 epiblast expansion, lineage segregation, bi-laminar disc formation, amniotic and yolk sac cavitation

70 y 33 of the ODHs (39%) were located within a laminar disinsertion.

71 There were laminar disinsertions in 50 eyes (96%) in the ODH+ group

72 nical information determined the presence of laminar disinsertions in each of the 48 positions with a

73 Laminar disinsertions occurred twice as frequently in ey

74 ts, the spatial concordance between ODHs and laminar disinsertions was poor.

75 The laminar distribution of alpha band activity appears more

76 tion, or TCA-derived glutamate, affected the laminar distribution of GABAergic interneurons in mouse

77 ed optogenetic raster stimulation to map the laminar distribution of GABAergic interneurons providing

78 acers was used to extend the notion that the laminar distribution of neurons interconnecting visual a

79 As for the laminar distribution of projections, axons originating f

80 xin B (CTb) into V1 and mapped the areal and laminar distribution of retrogradely labeled cells in ex

81 reas with different projection strengths and laminar distribution patterns and to certain contralater

82 This distinctive laminar distribution was observed by postnatal day 12 (P

83 This study compared the expression pattern, laminar distribution, and cell specificity of several rA

84 The regional and laminar distributions of [3H]CUMI-101 binding in baboon

85 monstrate the use of this method to quantify laminar distributions of synapses in mouse somatosensory

86 ortical layers and innervating complementary laminar domains, exhibited opposite activity changes dur

87 ion of eyes with violation of the ISNT rule, laminar dot sign, nasal shifting of the central vessels,

88 The laminar, electron-rich fluorophore as part of the macroc

89 distribution, and density of intraganglionic laminar endings (IGLEs), the predominant vagal GI affere

90 on within human temporal neocortex and local laminar excitability are linked to one another through a

91 In leaves, laminar expansion occurs as a result of balanced abaxial

92 GLT-1 exhibited a laminar expression pattern from P10-15 on, with the high

93 oral-expression patterns in human brains and laminar-expression profiles in the developing neocortex,

94 ngle NSCs to generate the correct number and laminar fate of cortical neurons.

95 Less well understood is how laminar fate transitions are regulated in cortical proge

96 whether these proneural genes also regulate laminar fate transitions.

97 gical cortical silencing revealed that cross-laminar feedback enhanced by dopamine relied on a positi

98 al) filaments demonstrates that species with laminar filaments exhibit balanced expression of abaxial

99 RNA-Seq data from species bearing laminar (flattened) or radial (cylindrical) filaments de

100 Two chips with laminar flow (0 degrees filament direction) or mixing fl

101 p, whose transcription is in turn induced by laminar flow and APLN/APLNR signalling.

102 xperiments with endothelial cells exposed to laminar flow and cocultured with pericytes confirmed tha

103 n excised whiskers in a flume in response to laminar flow and disturbed flow.

104 rms of microfluidic technology, single-phase laminar flow and multiphase microfluidics.

105 principle, we used the coupled microfluidic laminar flow and time-resolved two-photon excitation mic

106 The compact system was readily housed in a laminar flow cabinet allowing an ISO class-5 environment

107 While low-rate laminar flow commonly induces the classic shear stress r

108 ultured in a dynamic microfluidic chip under laminar flow compared to the static culture condition.

109 lops preferentially at sites where disturbed laminar flow compromises endothelial cell (EC) function.

110 the behavior of protein nanostructures under laminar flow conditions and their assembly mechanism int

111 ol particles through cylindrical tubes under laminar flow conditions using explicit analytical equati

112 Under laminar flow conditions, a redox reaction can be driven

113 cell debris is simultaneously removed using laminar flow conditions.

114 cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direc

115 pendent biochemical reaction conditions in a laminar flow device.

116 We found, firstly, that laminar flow fails to overcome the inflammatory effects

117 quantification of the penetration depth of a laminar flow field (i.e., the slip length) in a densely

118 A laminar flow forced convection model was used in the des

119 Contrary to laminar flow in most microfluidics, we find that the flo

120 Steady laminar flow induced the classic shear stress responses

121 er and the functionalized surface, created a laminar flow junction with a resulting reaction volume o

122 The combination of co-existing laminar flow manipulation and hydrodynamic single-cell t

123 wn abolishes the inhibitory effect of steady laminar flow on Bim.

124 se three mycotoxins was demonstrated via the laminar flow patterning of probes in an area of approxim

125 s below a threshold that interferes with the laminar flow profile or detector signals.

126 s a microfluidic technique that utilizes the laminar flow profile to continuously separate particles

127 Conversely, laminar flow protects against endothelial dysfunction, a

128 stems provide, they typically operate in the laminar flow regime under mass transfer limitations, whe

129 ese results, S4-depleted HUVECs in long-term laminar flow showed increased activation of proinflammat

130 particles are deflected through alternating laminar flow streams of reagents and washing solutions v

131 In contrast, the athero-protective laminar flow suppressed YAP/TAZ activities.

132 reach a mature morphology and acquire high, laminar flow that down-regulates DACH1.

133 ipoprotein, but confined by atheroprotective laminar flow through an upregulation of microRNA (miR)-1

134 acy, and suitability for mass manufacturing; laminar flow was studied to assess their suitability for

135 The laminar flow with negligible ionic diffusion between dif

136 nematics, is in this way regularized into a laminar flow with periodic velocity oscillations.

137 the vessel, the endothelial cells experience laminar flow, resulting in endothelial cell alignment in

138 Elevated laminar flow, TNFalpha and cigarette smoke extract syner

139 r study identified a molecular mechanism for laminar flow-activated LEC proliferation.

140 data reveal a molecular mechanism underlying laminar flow-induced lymphatic sprouting.

141 mechanotransduction pathway that translates laminar flow-induced shear stress to activation of lymph

142 Grx1 is markedly up-regulated by the steady laminar flow.

143 ased on the band broadening of a solute in a laminar flow.

144 ells [LECs]) were exposed to low-rate steady laminar flow.

145 ical vein endothelial cells (HUVEC) grown on laminar-flow perfusion channels were stimulated with 1 m

146 drag and fuel consumption for aircraft with laminar-flow surfaces.

147 In conjunction with laminar flows and fluorescence, we also show precise con

148 While the physics behind laminar flows has been studied for 200 years, understand

149 These observations support that, for laminar flows, erosion is a dynamical phase transition t

150 rate in the direction of applied forces from laminar fluid flow, but reversal of electro-osmotic flow

151 The cells were then exposed to laminar fluid shear stress of 12 dyn/cm(2).

152 provide a neurophysiological basis for human laminar fMRI and link human EEG and high-resolution fMRI

153 (BOLD) and cerebral-blood-volume (CBV)-based laminar fMRI and used these to discriminate four differe

154 tion factor that is thought to influence the laminar formation of the cerebral cortex.

155 current source density (CSD) analysis to the laminar FP profile.

156 In addition to a laminar framework, LCIC afferent-efferent patterns sugge

157 Downregulating Inx2 gap junctions within the laminar glial network causes beta-alanine accumulation i

158 The least common was laminar GMH.

159 abaxializing or adaxializing genes inhibits laminar growth, resulting in a mutant radialized phenoty

160 viewed for the presence of focal LC defects (laminar holes or disinsertions with a diameter >100 mum)

161 east one layer marker could be assigned to a laminar identity using canonical cortical layer marker g

162 n that carries weakly but finitely perturbed laminar inflow through gradual rather than abrupt transi

163 These results reveal a state-dependent laminar influence of Sst interneuron-mediated inhibition

164 y provides a template for attention-mediated laminar information processing that might be applicable

165 ree-dimensional flow fields of turbulent and laminar jets covering the Re range 10-10(4).

166 For laminar jets, the transition distance scales with L Re,

167 Current source density (CSD) analysis of laminar LFP profiles revealed alpha current generators i

168 hange of adaxial cell identity, outgrowth of laminar-like tissue on the inflorescence stem, and early

169 retinal cells were traced according to their laminar location during disease progression to look for

170 nformation flow through the network, and the laminar location of target neurons.

171 The laminar location of the cell bodies and terminals of int

172 more predictive of neuronal selectivity than laminar location or axonal projection target.

173 ons and cell types characterized by distinct laminar location, morphology, axonal projection, and ele

174 Here we characterized the laminar location, morphology, projection pattern, and ne

175 early postnatal age, ChCs and BCs differ in laminar location.

176 yer (IPL) that occur consistently at defined laminar locations.

177 layer 2, but only BCs are present in deeper laminar locations.

178 factors for SZ; (2) cell type markers or (3) laminar markers.

179 xcitatory neurons span the radial columns of laminar microcircuits, and excitatory neurons in differe

180 "Type 1" laminar/multilaminar hyperreflectivity (found in 24 scan

181 Guided further by theoretical analyses and a laminar multiphase fluid flow simulation, we show that t

182 Laminar multiunit activity and local field potential rec

183 vergent aspects of Lhx6(-)/(-) cell-fate and laminar mutant phenotypes and provide insight into a neo

184 Their laminar nature is not templated by an external surface,

185 measurement surface is near zero, due to the laminar nature of the flow, the contribution of the doub

186 We construct a laminar neural-field model of primary visual cortex (V1)

187 combined nonmassive choroidal and prelaminar/laminar optic nerve invasion, or scleral/extrascleral in

188 ombined non-massive choroidal and prelaminar/laminar optic nerve invasion.

189 Fluorescence laminar optical tomography (FLOT) provides depth-resolve

190 he entry nucleus of the basal ganglia, lacks laminar or columnar organization of its principal cells;

191 one has decreased seizure thresholds, but no laminar or dendritic defects in the cortex.

192 The Arabidopsis petal is a simple laminar organ whose development is largely impervious to

193 SC neurons have a laminar organization according to their function, with v

194 These results suggest a laminar organization for decision-related responses in d

195 ietal cortex (PC), but its topographical and laminar organization is not well characterized.

196 do not understand the temporal patterns and laminar organization of decision-related firing rates in

197 s largely been limited to brain regions with laminar organization of dendrites such as the hippocampu

198 ource density from the LFPs and compared the laminar organization of evolving sinks to those reported

199 We also reveal laminar organization of genes related to disease patholo

200 present study examined the topographical and laminar organization of insular projections to the parah

201 ct modes of neuronal migration necessary for laminar organization of neurons in the developing cerebr

202 ocalized activity patterns which reflect the laminar organization of neurons within a cortical column

203 r results clearly demonstrate a dorsoventral laminar organization of projections from the sensory cor

204 The laminar organization of the vertebrate retina enables sy

205 ure, the survival of retinal neurons, or the laminar organization of their dendritic and axonal compa

206 ry sensory cortices, for which principles of laminar organization, local connectivity, and parallel p

207 olecular phenotypes of cortical regional and laminar organization: hypoplasia of the frontal cortex,

208 sion of ab-ad genes results in inhibition of laminar outgrowth, leading to a radially symmetric struc

209 d filtration by plant stems of vegetation in laminar overland flow.

210 ression of each NFI protein shows a distinct laminar pattern in the adult mouse neocortex and that th

211 tonic similarity was strongly related to the laminar pattern of projection origins, and the absolute

212 f intraeye competition, allowing for correct laminar patterning and the even allocation of synaptic t

213 ative value to be assigned to differences in laminar patterning observed in different models, genotyp

214 nsitization, regulates regional identity and laminar patterning of the developing mouse neocortex in

215 Hence, the capillary flow field shows laminar patterns and a layer-specific analysis is valid.

216 The model accounts for laminar patterns and for the strength and topography of

217 Moreover, the intra-V1 laminar patterns of axonal projections identify two dist

218 rons born around the same time organize into laminar patterns with staggered terminations that stack

219 wn to be hydrodynamically well-defined, with laminar Poiseuille flow.

220 the peak broadening of a plug of solute in a laminar Poiseuille flow.

221 cal layers so that we could characterize the laminar position and physiological response properties o

222 al migration from a germinal zone to a final laminar position is essential for the morphogenesis of n

223 g the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct n

224 varied across VG3-AC arbors depending on the laminar position of neurites, with ON responses preferri

225 ction of this variation in neuron number and laminar position, which is produced principally from lay

226 of projection neurons, leading to persistent laminar positioning alterations.

227 ng neuronal morphology, and abnormalities in laminar positioning of primarily late-born neurons, indi

228 amacrine cells (dACs)--reach their specific laminar positions during development.

229 g Cblns 1, 2, and 4 tend to occupy different laminar positions within the dorsal spinal cord, and tha

230 ha band activity with a similar spectral and laminar profile in each of these sensory areas.

231 Origin, spatial extent, and laminar profile of bicuculline-induced interictal-like a

232 address these latter questions, we analyzed laminar profiles of local field potentials (LFPs) and co

233 To accomplish these, we analyzed laminar profiles of synaptic activity and action potenti

234 histochemistry and multireceptor analysis of laminar profiles.

235 Differences in laminar quantitative T2* between each patient group and

236 ity Score correlated each with the degree of laminar quantitative T2* changes, independently from whi

237 is cases, we tested for associations between laminar quantitative T2*, neurological disability, Multi

238 The flow within this system is laminar (Re < 1) and reaction rates are driven by enzyme

239 orthosilicate (TEOS) at the interface of two laminar reactant flows.

240 alography (MEG), computational modeling, and laminar recordings in animals, we present a new theory t

241 We show here, using local laminar recordings in freely moving mice, that slow wave

242 Laminar recordings in somatosensory neocortex from anest

243 a transition from a linearly stable coherent laminar regime to a non-desirable disordered turbulent s

244 son of in situ hybridization (ISH) images at laminar resolution.

245 bands show a differential relation with the laminar-resolved blood-oxygen level-dependent (BOLD) sig

246 Laminar resting-state fMRI showed directional functional

247 These proteins show laminar-restricted IPL localization and induce attractio

248 f selective pruning and elaboration, whereas laminar restriction results from biased outgrowth toward

249 o-opted by synaptic partners to ensure joint laminar restriction.

250 tterns such as vasoprotective unidirectional laminar shear stress (LSS) and atherogenic oscillatory s

251 nopus oocytes and examined their response to laminar shear stress (LSS).

252 Because laminar shear stress (SS) is a major physiological regul

253 tter understanding of the mechanism by which laminar shear stress activates lymphatic proliferation.

254 t arteries, where it integrates responses to laminar shear stress and regulates junctional integrity

255 der oscillatory, normal laminar and elevated laminar shear stress for a period of 72 hours.

256 Moreover, unidirectional laminar shear stress induced atheroprotective CD39 expre

257 The ex vivo perfusion of arterial laminar shear stress to isolated veins further confirmed

258 also showed decreased RhoA activation under laminar shear stress.

259 sion of proliferation, phenotypes induced by laminar shear stress.

260 Using a custom laminar-shear flume to image slow granular dynamics deep

261 oliferative and post-mitotic layers, wherein laminar signatures reflect cellular composition and deve

262 so understand the fundamental physics of the laminar skin friction coefficient and the related drag r

263 However, differences in laminar sources and magnitude of distant cortical input

264 trated considerable cell-type specificity in laminar sources of local inputs.

265 aptic function in L4 and L2/3 of A1, but via laminar specific mechanisms.

266 m of dark exposure (DE) for 1 week, produces laminar-specific changes in excitatory and inhibitory ci

267 This laminar-specific fMRI onset allowed us to identify the n

268 gene co-expression network analysis of human laminar-specific neocortical expression data showed that

269 Laminar-specific synaptic wiring diagrams of excitatory

270 ture artery-type shear stress (high, uniform laminar) specifically down-regulated DACH1, while the re

271 During this period of laminar stability, RGC arbors undergo structural rearran

272 evelopmental abnormalities; and the possible laminar structural defect noted in many patients are fin

273 The laminar structure and conserved cellular organization of

274 The mammalian neocortex has a repetitious, laminar structure and performs functions integral to hig

275 entangling signal by taking advantage of the laminar structure of many biological specimens.

276 is organized in clusters, in contrast to the laminar structure of the mammalian cortex [7].

277 es organize their neurites into an intricate laminar structure that underlies visual processing.

278 Mammalian cortex is a laminar structure, with each layer composed of a charact

279 cephalon and for the formation of its normal laminar structure.

280 choreographs neuronal migration to establish laminar structures during brain formation.

281 d structures while DOPC promotes more stable laminar structures.

282 r and posterior displacement of ONH/anterior laminar surfaces (P >/= 0.678).

283 sterior displacement of the ONH and anterior laminar surfaces (P </= 0.009).

284 The ONH and anterior laminar surfaces displaced not only posteriorly but also

285 (IOP) during follow-up, the ONH and anterior laminar surfaces displaced posteriorly by 1.6 mum and 2.

286 The laminar synaptic connections are symmetric sparse, rando

287 Laminar T2* changes may, thus, result from cortical path

288 Dscam in promoting cell death, spacing, and laminar targeting of neurons in the developing mouse ret

289 placing them in an ideal position to mediate laminar targeting.

290 We show that although never laminar, the tuning of DS-RGC axons targeting the mutant

291 d: the temperature-dependent transition from laminar to turbulent vortex motion and the decoupling fr

292 otemporal organizations of vorticity in both laminar-to-turbulence transitioning and very low Reynold

293 plete spatial concentration distribution for laminar tube flow; the obtained simple description is sh

294 ication of a strong instability leading to a laminar-turbulent phase transition through a self-consis

295 f our quantitative knowledge about total and laminar variation in cortical neuron numbers and neuroge

296 imates the maximum principal shear stress of laminar viscous stress (PLVS), and overestimates the max

297 dea, we found that neurons located in a thin laminar zone at the L3/5A border in the forelimb area of

298 apses were not identified in the superficial laminar zone.

299 ojections, within the superficial and middle laminar zones of the human DLPFC.

300 In both laminar zones, Type II PV-IR synapses from interneurons