ライフサイエンスコーパス: laminin 10

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1 odule of laminin alpha5 chain in adhesion to laminin-10.

2 l epithelium, although not as efficiently as laminin-10.

3 ced by alpha3beta1-mediated cell adhesion to laminin 10/11 in extracellular matrix.

4 tion of laminin 1 in Reichert's membrane and laminin 10/11 in the surrounding decidual matrix, sugges

5 the trophectoderm basement membrane, whereas laminin 10/11 is expressed only in the inner cell mass a

6 In the uterus, laminin 10/11 is strongly expressed in the decidualizing

7 m migration and decreases spreading, whereas laminin 10/11 promotes both spreading and persistent mig

8 Sol-Lu bound specifically to laminin-10/11 (alpha5beta1/beta2gamma1) in enzyme-linked

9 Laminin alpha5 subunit-containing laminin-10/11 (LM-511/521) is the major laminin in the t

10 In primary dental epithelium culture, laminin-10/11 promotes cell growth, spreading, and filop

11 3 results in decreased cell migration toward laminin-10/11, and 3) selective caspase-3 inhibitor bloc

12 The extracellular matrix protein, laminin-10/11, but not collagen I, induces integrin- and

13 site of caspase-3 in iPLA(2)) to Ala blocks laminin-10/11-induced cleavage and activation of overexp

14 lls and suggest that the interaction between laminin-10/11-integrin alpha6beta4 and the phosphatidyli

15 in iPLA(2) activation and cell migration to laminin-10/11.

16 mportant for enhancing cell migration toward laminin-10/11.

17 dhesion to laminin-2/4 or strong adhesion to laminin-10/11.

18 ks cleavage of endogenous iPLA(2) induced by laminin-10/11.

19 n strong cell-cell contacts on substrates of laminins 10/11, and exhibit strong staining of VE-cadher

20 drawal was significantly smaller in cells on laminin (10 +/- 2 %) than on glass (48 +/- 5 %) (P < 0.0

21 e mouse hippocampus, neuron interaction with laminin-10 (alpha5,beta1,gamma1) protects against neuron

22 endoderm differentiates, apparently because laminin 10 (alpha5beta1gamma1) partially compensates for

23 The laminin alpha5 chain is a component of laminin-10 (alpha5beta1gamma1) and -11 (alpha5beta2gamma

24 Here, we describe the essential role of laminin-10 (alpha5beta1gamma1) in hair follicle developm

25 ide (AQARSAASKVKVSMKF) in the alpha-chain of laminin-10 (alpha5beta1gamma1), a prominent basement mem

26 nt membrane (GBM) components collagen IV and laminin 10 and 11.

27 , whereas in normal corneas MMP-10 decreased laminin-10 and integrin alpha(3)beta(1) expression.

28 an-cultured DR corneas, cystatin C increased laminin-10 and integrin alpha(3)beta(1), whereas in norm

29 f the laminin-1 gamma1 chain with endogenous laminin-10, because infusion of anti-laminin gamma1 anti

30 HDMECs expressed laminin-8 and laminin-10, but no other laminins, as determined by radi

31 3 beta 1 specifically bound to laminin-5 and laminin-10, but not to laminin-1, laminin-2, fibronectin

32 ascular basement membrane (BM) constituents, laminin 10, collagen IV, and nidogen-2 (but not perlecan

33 E16.5 Lama5 -/- mouse skin, lacking laminin-10, contained fewer hair germs compared with con

34 y, treatment of Lama5 -/- skin with purified laminin-10 corrected basement membrane defects and resto

35 cluding sonic hedgehog and Gli1, implicating laminin-10 in developmental signaling.

36 ns were downregulated, suggesting a role for laminin-10 in hair development.

37 We conclude that laminin-10 is required for hair follicle development and

38 of human scalp xenografts with antibodies to laminin-10, or its receptor beta1 integrin, produced alo

39 pithelial cells to the peptide compared with laminin-10 was determined by colorimetric adhesion assay

40 Laminin-10 was present in the basement membrane of elong

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