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1      These results require confirmation in a large-scale clinical trial.
2 RT has not been systematically assessed in a large-scale clinical trial.
3  requires difficult-to-conduct and expensive large-scale clinical trials.
4  due to the lack of conclusive evidence from large-scale clinical trials.
5 e stress in CVD remain to be investigated in large-scale clinical trials.
6 hich are unknown and need to be evaluated in large-scale clinical trials.
7 fficacy of a microbicide before embarking on large-scale clinical trials.
8  by GlaxoSmithKline and Merck have completed large-scale clinical trials.
9  as relatively ineffective when entered into large-scale clinical trials.
10  promising agents have been disappointing in large-scale clinical trials.
11  subtypes are amenable to properly designed, large-scale, clinical trials.
12 cular AMD was lower than that recommended by large-scale clinical trials, and rates of discontinuatio
13 o significantly improve glycaemic control in large-scale clinical trials, and short-term ranolazine t
14 s to reduce cardiovascular mortality, before large scale clinical trials are undertaken.
15                             Clearly targeted large-scale clinical trials are needed to evaluate the r
16 pproaches be vigorously pursued and that any large-scale clinical trial be carefully executed to avoi
17 l global assays of fibrinolysis will require large-scale clinical trials before their prognostic powe
18  will aid pharmaceutical companies to design large-scale clinical trial by assessing potentially haza
19   To date, there are no published results of large-scale clinical trials comparing conventional doses
20                                          Few large scale clinical trials exist with biopsy or magneti
21 me these limitations and have been shown, in large-scale clinical trials for acute coronary syndromes
22 -CoV for humans or animals, and there are no large-scale clinical trials for therapies against MERS-C
23                                     A recent large-scale clinical trial found that an initial invasiv
24 ins a relatively rare disorder, and as such, large-scale clinical trials have not been completed, ren
25                                         Only large-scale clinical trials, however, can determine the
26 ould be a more informative test, and propose large-scale clinical trials in patients who are believed
27                                   In robust, large-scale clinical trials of grass pollen sublingual t
28 gents in resistant patient populations, with large-scale clinical trials ongoing to more thoroughly t
29                                     Existing large-scale clinical trials such as the GISSI-Prevenzion
30 n anaesthesia has recently been evaluated in large-scale clinical trials that have demonstrated xenon
31 ics, this strategy has not been subjected to large-scale clinical trials to establish safety and clin
32                                         In a large-scale clinical trial, treatment with Herceptin (tr
33 ventions, should they be proven effective in large-scale clinical trials using appropriate controls,
34                      The failure of numerous large-scale clinical trials, which aimed to treat sepsis
35 n isolated MR and provides the impetus for a large-scale clinical trial with clinical outcomes.

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