ライフサイエンスコーパス: large-scale study

1 this practice has not been evaluated in any large scale study.

2 for the data set, consistent with a previous large-scale study.

3 ndicator and should be further explored in a large-scale study.

4 to scale up the technique and to adapt it to large scale studies.

5 icient technique, thus it is able to fulfill large scale studies.

6 edure which makes this approach suitable for large scale studies.

7 rent reference haplotypes are inadequate for large-scale studies.

8 taken before analysing accelerometer data in large-scale studies.

9 population stratification in these types of large-scale studies.

10 g, which is a major source of variability in large-scale studies.

11 sure time, but this has not been verified in large-scale studies.

12 ethods are often prohibitively expensive for large-scale studies.

13 sible screening test, but there have been no large-scale studies.

14 nd Central Asia) have rarely been sampled in large-scale studies.

15 tool to detect likely technical artifacts in large-scale studies.

16 hese populations has yet to be determined in large-scale studies.

17 icant improvements over cartridge arrays for large-scale studies.

18 cs and personalized medicine by facilitating large-scale studies.

19 nd relate it to previous non-tissue-specific large-scale studies.

20 ystem are obstacles to its widespread use in large-scale studies.

21 alid data within the resource constraints of large-scale studies.

22 cly available metagenomic samples from eight large-scale studies.

23 g region using models compiled from multiple large-scale studies.

24 ods and highlight the application of BiFC in large-scale studies.

25 mitis were low and similar to those in other large-scale studies.

26 further validated with PET-autopsy data from large-scale studies.

27 and endoscopic tools requiring validation in large-scale studies.

28 ss the various challenges these data pose to large-scale studies.

29 lected on filter paper and can be applied to large-scale studies.

30 on to the European Union proposals through a large-scale study (2.7 million birds) with the unprecede

31 Large-scale studies aimed at a molecular understanding o

32 s thus open up the possibility of conducting large-scale studies analyzing thousands of samples simul

33 The technique is well suited for large scale studies and for analysis of clinical samples

34 blood spot and in principle is suitable for large scale studies and newborn screening.

35 Recent large-scale studies and converging findings are beginnin

36 generalizable approach that is suitable for large-scale studies and will enable the field to obtain

37 n of the types of prenylation in proteins in large-scale studies and will improve significantly our k

38 increasingly available from both small- and large-scale studies, and can be viewed as a network.

39 ly been noted that errors are frequent among large-scale studies, and that error frequency depends on

40 ight provide a simple, cheap alternative but large-scale studies are again needed.

41 However, large-scale studies are currently difficult to set up be

42 Additional multicenter, large-scale studies are needed to develop more complete

43 Large-scale studies are needed to evaluate whether exces

44 Large-scale studies are needed to investigate the effect

45 Further large-scale studies are needed to understand better the

46 Although large-scale studies are required to change current follo

47 Additional large-scale studies are warranted for these complex phen

48 Further large-scale studies are warranted to confirm the potenti

49 Large-scale studies are warranted to evaluate whether di

50 Large-scale studies are warranted to identify individual

51 Robust, large-scaled studies are required to better quantify the

52 e occurrence of which, based on contemporary large-scale studies, are unlikely to have important clin

53 of early nutrition has been defined in most large-scale studies as beginning within 48 h of intubati

54 This large-scale study assessed cognitive and behavioral func

55 This large-scale study based on nationwide data from Sweden a

56 We performed a large-scale study by creating breast cancer metastasis n

57 Evidence comes from a large-scale study conducted with 10 measures of independ

58 cessing of N-linked glycans would facilitate large-scale studies correlating the glycome with disease

59 In this large-scale study, delaying revascularization with PCI>2

60 al.'s bottom-up approach, we conducted four large-scale studies designed to assess people's concepti

61 nterest in incorporating this technique into large-scale studies, e.g., clinical and molecular phenot

62 urrent research efforts, with an emphasis on large-scale studies, emerging technologies, and challeng

63 ial to create substantial false positives in large-scale studies even when a small fraction of marker

64 ci associated with lipid traits, however, no large-scale studies exist for Hispanics and other minori

65 However, not a single large-scaled study exists to investigate the optimal pos

66 This large-scale study explored a standardized methodology fo

67 This large-scale study has enabled in-depth analyses on how p

68 However, no large-scale study has examined psychiatric disorders aft

69 To date, no large-scale study has examined the comorbidity and conti

70 However, no large-scale study has yet estimated the number of expect

71 No large scale studies have evaluated so far what symptom d

72 Moreover, few large-scale studies have assessed asymmetries of subcort

73 Several large-scale studies have attempted to identify mRNAs bou

74 ies with morphea subtype or severity, but no large-scale studies have been conducted.

75 cts of TIPS have been confirmed, however, no large-scale studies have been focused on technical analy

76 the most promising susceptibility genes, but large-scale studies have been lacking.

77 Large-scale studies have clarified a number of long-susp

78 Few large-scale studies have considered both food sources an

79 Recent large-scale studies have created genome-scale catalogs o

80 actor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile o

81 To the authors' knowledge, no large-scale studies have examined the effects of languag

82 So far, no large-scale studies have focused on defining a comprehen

83 such as measles-mumps-rubella immunization, large-scale studies have not supported such links.

84 far more prevalent and severe than previous large-scale studies have portrayed.

85 een shown to predict warfarin dosing, but no large-scale studies have prospectively evaluated the cli

86 Few large-scale studies have quantified and characterized th

87 Large-scale studies have revealed how editing is regulat

88 through sites in open reading frames (ORFs), large-scale studies have shown such targeting to be gene

89 Recently, a large-scale study highlighted some of the benefits of ca

90 Small invertebrates are ideal for these large-scale studies; however, patch-clamp electrophysiol

91 X-PCR fingerprinting is more appropriate for large-scale studies (i.e., global epidemiology).

92 Recent large-scale studies illustrate the importance of electro

93 This large-scale study implicates an aetiological role of the

94 Large-scale studies in clinical populations are needed t

95 Acamprosate (grade A, from large-scale studies in Europe) reduces drinking frequenc

96 These observations may help guide future large-scale studies in examining host SNPs for their cli

97 fy the underlying disease-causing genes, but large-scale studies in human cellular models have previo

98 risk factors for cardiovascular disease from large-scale studies in humans.

99 variability of the results while conducting large-scale studies in investigative pathology and oncol

100 s is increasingly being recognized, previous large-scale studies in schizophrenia (SZ) have primarily

101 d by genome-wide association studies (GWAS), large-scale studies in which the entire genome is covere

102 A large-scale study in maize generated 40,299 HMPR sequenc

103 Here, we present a large-scale study in which we investigated duplicate ret

104 or family-based association tests (FBATs) in large-scale studies, including genome-wide association s

105 Recent large-scale studies, including those of Behrends et al.

106 equires extensive manual review, which makes large-scale studies inconvenient.

107 This large-scale study indicates structural thalamic abnormal

108 datasets is a complex but essential task for large-scale studies investigating protein-protein intera

109 To date, there have been few large-scale studies investigating the postoperative outc

110 d in medicine, particularly surgery, with no large-scale studies investigating their training experie

111 This large-scale study investigating key aspects of the PANDA

112 However, large-scale studies involving classical type I and type

113 g data, the qMSAT is especially valuable for large-scale studies involving rare variants, as it can p

114 In a large-scale study involving 55 species and 550 populatio

115 A large-scale study is needed to investigate the outcome o

116 The main purpose of this large-scale study (n = 185) covering a wide age range of

117 labor-intensive methodology have limited the large-scale studies necessary for statistical validation

118 ocols dedicated to CAAs can give rise to the large-scale studies needed to define the prognosis and o

119 Especially in large-scale studies, normalization is crucial for drawin

120 ieved to have adverse health effects; recent large scale studies now confirm relationships between ch

121 throughput experimental data (e.g. data from large scale studies of gene expression and polymorphism

122 Advances in proteomics and large scale studies of potential mitochondrial proteins

123 This first, large scale study of PR gene regulation has important im

124 We conducted a large scale study of the distribution of protein domains

125 However, there are no large-scale studies of actual PSA screening practices in

126 are being deposited into this database from large-scale studies of Arabidopsis thaliana and soybean.

127 We discuss the feasibility of large-scale studies of asymptomatic at-risk subjects tha

128 Here, we combined tools used in large-scale studies of biodiversity (remote sensing and

129 nical variability, which allows its usage in large-scale studies of chromatin from normal or diseased

130 Yet recent large-scale studies of community regulation in marine ec

131 Few large-scale studies of epilepsy have been done in sub-Sa

132 Recent large-scale studies of evolutionary changes in gene expr

133 As large-scale studies of gene expression with multiple sou

134 nd validated human transcribed sequences for large-scale studies of gene expression.

135 Overall, we show that large-scale studies of gene function in model organisms

136 ophila melanogaster is a promising model for large-scale studies of genes involved in the pathogenesi

137 the mSFP identified will greatly facilitate large-scale studies of genome variation in the P. falcip

138 ng to generate new trisomic mouse models and large-scale studies of genotype-phenotype relationships

139 We review recent large-scale studies of habitat adaptation, with emphasis

140 autism, and it is extensively used in other large-scale studies of human diseases.

141 d by selected examples, our approach enables large-scale studies of human neurons for questions such

142 ying gene-environment interactions (GxEs) in large-scale studies of human populations.

143 Recent large-scale studies of individuals within a population h

144 Whole HIV-1 genome sequences are pivotal for large-scale studies of inter- and intrahost evolution, i

145 Large-scale studies of linkage disequilibrium (LD) have

146 To carry out large-scale studies of LOH and MI in cancer progression,

147 near-full-length sequences for three recent large-scale studies of microbial communities in the mous

148 the field of animal migration [1] that only large-scale studies of migration patterns across a speci

149 Large-scale studies of morbidity and mortality in unsele

150 Large-scale studies of mRNA expression have displayed th

151 No large-scale studies of mutation identification and scree

152 Supporting this view, large-scale studies of national African demographic surv

153 should be carefully reviewed before further large-scale studies of patients with sepsis are conducte

154 analyses of mRNA and protein expression, but large-scale studies of protein dynamics and turnover hav

155 s--and actual fluorescent imagesfrom ongoing large-scale studies of protein localization in S.cerevis

156 Large-scale studies of relatively homogeneous samples, i

157 d preterm delivery found in this study, more large-scale studies of temperature and preterm delivery

158 filter paper may increase the feasibility of large-scale studies of the determinants of insulin sensi

159 Large-scale studies of the dynamic phosphorylation state

160 However, large-scale studies of the effects on cardiovascular out

161 Moreover, these findings should motivate large-scale studies of the longitudinal expression in pa

162 e quantification tools are a prerequisite to large-scale studies of the molecular mechanisms of subce

163 ed genes has long fascinated biologists, but large-scale studies of their expression dynamics and mol

164 asurement of thousands of proteins, enabling large-scale studies of various biological systems.

165 They have also enabled large-scale studies of vertebrate genome evolution, as w

166 ster model is a promising minihost model for large-scale studies of virulence mechanisms and antifung

167 study presents longitudinal evidence from a large-scale study of >2,000 children ages 6-12 living in

168 A large-scale study of causative allergen components of sh

169 In the first large-scale study of deadwood in Central Africa, we quan

170 smission between related individuals, but no large-scale study of families that would reflect the typ

171 A large-scale study of fungal genomics provides new insigh

172 We have conducted a large-scale study of gene expression in the C4 monocot s

173 Finally, we apply our approach to a large-scale study of immune system variation.

174 cale up makes QuMFRA a valuable tool for the large-scale study of macromolecular interaction.

175 We evaluated this hypothesis with a large-scale study of mitochondrial DNA (mtDNA) and Y-chr

176 To our knowledge, this is the first large-scale study of mtDNA variation in single malignant

177 otein families and apply DCA to a systematic large-scale study of nearly 2,000 Pfam protein families

178 viously reported enzyme knockout study and a large-scale study of plasma samples.

179 We performed a large-scale study of protein homooligomers in terms of t

180 scribe the formation of a group dedicated to large-scale study of PTSD genetics: the PGC-PTSD.

181 Here, we report a large-scale study of resting state functional connectivi

182 In a large-scale study of socioeconomically homogeneous men t

183 Here, we report on the first large-scale study of the accuracy and reliability of lat

184 Here, we present findings from a large-scale study of US SFES, who are widespread and inc

185 We have undertaken a large-scale study of various tissues from normal control

186 We conducted a large scale study on the sxt gene and toxin distribution

187 methodology could potentially be applied in large-scale studies on fruit quality, authenticity/varie

188 We review and integrate the recent in-depth large-scale studies on human immune diversity and its po

189 cellular trafficking, and this has motivated large-scale studies on lipid pathways.

190 differentially expressed genes in subsequent large-scale studies on the same platform, but in which t

191 Here, we present a large-scale study on a non-redundant set of about 20,000

192 Here, we describe a large-scale study on assigning function to unknown membe

193 Through a large-scale study on mammalian miRNA turnover, we report

194 This paper describes a large-scale study on the nature and the energetics of th

195 In large scale studies, once miRNAs of interest have been i

196 that are either too labor intensive to allow large-scale studies or not sufficiently quantitative to

197 miquantitative profiling data from different large scale studies over the time course of years, the m

198 This large-scale study overcomes the challenges associated wi

199 This large-scale study potentially resolves the complex relat

200 This large-scale study provides important insights into the m

201 In large-scale studies, RFLP typing has practical processin

202 Further large-scale studies should be done to confirm our findin

203 Ongoing large-scale studies should help clarify such outstanding

204 and epilepsy), and (3) additional data from large-scale studies, smaller cohorts, and case reports f

205 For large-scale studies, submitting short phrases encased in

206 This large-scale study substantially enhances our understandi

207 ting rare variant associations identified in large-scale studies, such as exome re-sequencing project

208 will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project.

209 n, as well as the scarcity of comprehensive, large-scale studies that assess both the genomic landsca

210 Large-scale studies that have been recently conducted an

211 ese phenotypes, there is currently a lack of large-scale studies that have specifically examined the

212 re is no definitive evidence from published, large-scale studies that one approach is superior to the

213 We present a large-scale study that compares the sequences and best e

214 We used available proteomic data from large scale studies to narrow down potential phospho-tyr

215 Large-scale studies to better address post-explantation

216 However, large-scale studies to detect long-term trends of C and

217 amined over 3,800 unique MRI scans from nine large-scale studies to estimate the morphometricity of a

218 There is a need for large-scale studies to generate robust data for testing

219 ific for the functional gene is critical for large-scale studies to identify the role of the PRNP gen

220 ease has been poorly explored, and this is a large-scale study to ascertain the association between d

221 Our results warrant a large-scale study to examine the effect of the A133S pol

222 A large-scale study to identify functional variants in G-p

223 Here we have undertaken a large-scale study to investigate the existence of duplic

224 At this time, these large-scale studies typically utilize a simple kinetic m

225 l and public policy recommendations, but few large-scale studies use 24-h urine collections.

226 However, large-scale studies using sensitive measurements of HIV

227 In large-scale studies, virtually every chip contains some

228 In the context of this large-scale study we obtained a false positive rate of a

229 To meet the challenges in making feasible large-scale studies, we present the REgional heritabilit

230 nd to examine the reported interactions in a large-scale study.We systematically reviewed studies rep

231 Applying this strategy to large-scale studies will greatly reduce the time and cos

232 Although a large-scale study will be necessary to confirm clinical

233 However, further large scale studies with longer follow up period is nece

234 al environment in which to analyze small- to large-scale studies with data from the latest genotyping

235 Future large-scale studies with functional characterization of

236 No large-scale studies with long-term oncological outcomes

237 t that the concept of defense is useful, but large-scale studies with representative cohorts are lack

238 However, the power gain is small (1) for large-scale studies with thousands of individuals, becau