ライフサイエンスコーパス: largest

1 m 20% in the smallest neonates to 90% in the largest.

2 h people aged older than 65 years having the largest absolute decreases in diabetes incidence.

3 ntial increases in the frequency of the very largest accumulations above a physical cutoff scale, inc

4 to >1,000% in the probability density of the largest accumulations that have historical precedents.

5 unfavorable renal cell carcinoma [RCC]), the largest adjuvant trial published to date.

6 fold difference in mass between smallest and largest adults.

7 The largest advances were on limber pine-dominated granitic

8 The differences in obesity risk were largest after 5 y of age and persisted into adolescence.

9 calculated using summary statistics from the largest Alzheimer's disease genome-wide association stud

10 Reductions in bleeding were largest among those undergoing transfemoral PCI, whereas

11 fire spread, angiosperm shrubs delivered the largest amount of heat per unit area.

12 Conclusion To our knowledge, this is the largest analysis of data for anti-programmed death-1 the

13 pediatric peanut OIT trials, comprising the largest analysis of peanut OIT safety to date.

14 a forest connection 1 km in width among the largest and closest fragments at 11 locations.

15 The largest and deadliest outbreak occurred in Angola in 200

16 that caused the simulated biting rates to be largest and mosquito mortality rates and extrinsic incub

17 onduit for genetic engineering, as it is the largest and most accessible organ, epidermal autografts

18 ADH:ubiquinone oxidoreductase) is one of the largest and most complicated enzymes in mammalian cells.

19 our knowledge, the iPSYCH2012 sample is the largest and most comprehensive data source for the combi

20 G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in

21 of historic and modern populations using the largest and most geographically representative sample of

22 INTERPRETATION: The largest and most robust differences between the eyes of

23 % of Antarctica that is ice free, whilst the largest animals that have ever lived on Earth (Blue and

24 vio-deltaic Bengal Aquifer System (BAS), the largest aquifer in south Asia.

25 theast and southwest regions and thus on the largest archaeogenetic dataset from the Peninsula to dat

26 RIL) hyperreflective foci (HRF), average and largest area of intraretinal (IR) cysts, and extent of d

27 y are studied in different size regimes: the largest aromatic molecules have diameters of about one n

28 i Bay, Milos Island, Greece, are part of the largest arsenic-CO2-rich shallow submarine hydrothermal

29 ociation studies (GWAS) data from two of the largest ASD family cohorts, the Autism Genetics Resource

30 The largest association for respiratory hospitalizations, a

31 chalcogenides such as GeS, which display the largest band edge responsivities reported so far.

32 One of the largest barriers to overcome is to achieve a stable PEC

33 The mean largest basal diameter was 11 mm (median, 12 mm; range,

34 sc diameter from optic nerve), the mean (SD) largest basal diameter was 18.1 (1.9) mm and mean height

35 The largest benefits occurred between sedentary patient grou

36 Soils represent the largest carbon reservoir within terrestrial ecosystems.

37 ajor depressive disorder (MDD) is the second largest cause of global disease burden.

38 The largest cause-specific differences between those with an

39 diatric renal transplant recipients in the 2 largest centers in the United Kingdom, sharing the same

40 Sc and their radiative impact is one of the largest challenges for global climate models.

41 increasing mean annual temperature, with the largest changes for annuals and individuals occurring in

42 The largest changes in expression plasticity were observed b

43 Processes which displayed the largest changes in protein abundance were peptidoglycan

44 succeeded Hofmann, the DChG was the world's largest chemical society.

45 Latin America has experienced two of the largest cholera epidemics in modern history; one in 1991

46 oupled receptors (GPCRs)-which represent the largest class of both human membrane proteins and drug t

47 DOMAIN (IQD) family emerged as possibly the largest class of CaM-interacting proteins with undefined

48 abbreviated new drug applications, with the largest class of products being liposomal formulations i

49 ort a lack of cross-genotype immunity in the largest cohort of people to date.

50 tellite-tracked drifter trajectory data, the largest collection so far considered.

51 riants were identified in one of the world's largest collections of clinical WES referral tests (N=65

52 In the largest combined sample to date, we identified a novel a

53 ticeable anisotropy, with kappa zz being the largest component and [Formula: see text] being about 25

54 sposable elements (TEs) represent the single largest component of numerous eukaryotic genomes, and th

55 ifferent fire seasons were evident, with the largest contributions during the summer when wildfires o

56 any nations in the 1980s and 1990s, with the largest contributions from leaded gasoline emissions.

57 ons is remarkably small (</=2%) and that the largest contributions to deltaR are deltaepsilon and del

58 affected region relative to GDP and also the largest contributor to global absolute costs.

59 The largest contributors to cost were clinical nurse time fo

60 Cattle, especially calves, are the largest contributors, followed by chickens and pigs.

61 INTERPRETATION: This is the largest controlled trial conducted in SPS patients and d

62 lock gene expression and one of the planet's largest daily migrations of biomass.

63 a desktop computer was <15 min even for the largest dataset tested, which included all coding sequen

64 By cancer type, the largest decrease in percent uninsured occurred in patien

65 Haiti had the largest decreasing trend because of continuous deforesta

66 membranes, which collectively represent the largest described number of sound sources for a vocal or

67 ce explained by any biomarker (2.8%) and the largest difference in LAZ predicted between the 5th and

68 higher risk for 30-day readmission, with the largest differences at younger ages.

69 The largest differences between flours were found in the con

70 fidence interval, -.012 to -.0024), with the largest differences observed in those with prior clinica

71 The largest differences were in carotenoids, including lycop

72 or and inferior temporal clock hours had the largest differences.

73 the peeling test is observed to exhibit the largest distance for detachment because it separates via

74 were observed; however, these increases were largest during the first 12 months.

75 e SNPs in transgenic flies, we show that the largest effect is caused by an amino acid polymorphism t

76 e shape, volume, and loop flexibility, their largest effect is in altering the solvent accessibility

77 Age had the largest effect on all Child SCAT3 components, with child

78 tant, whereas triple-negative tumors had the largest effect on BCD.

79 The last variable had the largest effect on Cr(VI) reduction kinetics: for both cl

80 Deletions appear to have the largest effect on pseudogene formation and loss of regul

81 Stage at diagnosis had the largest effect on racial/ethnic survival disparities, bu

82 quency CYP2R1 coding variant that exerts the largest effect upon 25OHD levels identified to date in t

83 This largest effort to date in weedy plant genomics gives a b

84 n under future warming for the world's third-largest electricity market-the 35 countries of Europe.

85 anosized structural topology with one of the largest energy barriers reported to-date for high-nuclea

86 expression of ASD-associated genes, with the largest enrichments in genes known to harbor rare highly

87 ary, produce what might have been one of the largest episodes of transient climate change in Earth hi

88 69% is missing, with the sentinel SNP of the largest eQTL explaining 87% (0.052/0.060) of the varianc

89 iscrete algorithm to efficiently compute the largest equivalence, building on approaches rooted in co

90 n Ebola virus disease (EVD) outbreak was the largest EVD outbreak in history.

91 The Pawnee M5.8 earthquake is the largest event in Oklahoma instrument recorded history.

92 he isotopic data reported here are among the largest ever observed in pyrite, and are in phase with g

93 In the largest ever study of clinical isolates, we surveyed adh

94 eta-analysis for nicotine dependence and the largest-ever cross-ancestry GWAS meta-analysis for any s

95 In this largest-ever GWAS meta-analysis for nicotine dependence

96 ole in drug therapy and represent one of the largest families of drug targets.

97 Turnip mosaic virus, a member of one of the largest families of plant-infecting viruses, increases v

98 The largest families, Acrididae and Cicadellidae, were susce

99 Chrysopidae (green lacewings) is the second largest family in Neuroptera, and it includes medium-siz

100 Coeloplanidae, the largest family of benthic ctenophores, comprises 33 spec

101 at regulates the phosphatase activity of the largest family of bifunctional histidine kinases in resp

102 ogenous and synthetic ligands, represent the largest family of druggable targets in the human genome.

103 Lactose permease (LacY), a paradigm for the largest family of membrane transport proteins, catalyzes

104 stic cells (DENN) domain have emerged as the largest family of Rab-activating guanine nucleotide exch

105 Eph receptors comprise the largest family of receptor tyrosine kinases (RTKs), with

106 G protein-coupled receptors (GPCRs), the largest family of signaling receptors, are critically re

107 zinc-finger proteins (KRAB-ZFPs) make up the largest family of transcription factors in humans.

108 he Big Bang, in regions corresponding to the largest fluctuations in the cosmic density field.

109 entified that total fluid volume (P = .002), largest fluid volume pocket (P = .002), max fluid area (

110 ctal carcinoma and ductal carcinoma in situ (largest focus, 3.5 cm).

111 f an important pathogen affecting one of the largest food animal industries in the world.

112 cially marked in soybean, the world's fourth largest food crop in terms of seed production, and the m

113 wasted, while the specific impact per kg is largest for beef.

114 This peak was largest for infants aged 9-25 weeks.

115 indicate that the pulling test requires the largest force and the shortest distance to detachment as

116 The transatlantic slave trade was the largest forced migration in world history.

117 than all living otters, and ranks among the largest fossil otters.

118 Alkenes and aromatics contributed to the largest fractions of photochemical reactivity, suggestin

119 c changes in Lake Superior, which is Earth's largest freshwater lake by area, are not well documented

120 ure shows that the S-layer is porous, with a largest gap dimension of 27 A, and is stabilized by mult

121 ' superphylum, the Mia14 lineage has had the largest gene flux, with dozens of genes gained that are

122 The largest genera (Lactococcus) decreased from 33.03% to 7.

123 rom yeast whole-cell extract with TFIIH, the largest general transcription factor required for transc

124 re performed for microRNAs using data of the largest genome-wide association meta-analysis of AA to d

125 gene polymorphisms for schizophrenia in the largest genome-wide association study conducted to date

126 Foamy viruses have the largest genomes among mammalian retroviruses and their v

127 ce; (iv) ecotypes that currently exhibit the largest geographic distribution and niche breadth appear

128 ious intent to responsibly bring the world's largest global health effort to a close and to protect a

129 Wetlands are the largest global source of atmospheric methane (CH4), a po

130 The largest group of translocated proteins from oomycetes is

131 We selected variants, reported in the largest GWAS to date, associated with genes involved in

132 onic database of Clalit Health Services, the largest health care provider in Israel.

133 h a multiyear multisite review at two of the largest health care systems in the United States.

134 In 2013, the largest health condition leading to health care spending

135 and changes over time were found among the 3 largest Hispanic subgroups in the United States.

136 llance for rotavirus hospitalizations at the largest hospital in Zanzibar, Tanzania, from 2010 throug

137 nts of emergency hospital visits from the 28 largest hospitals in 26 Chinese cities from Sept 9, 2013

138 missions (n = 433,037 admissions) from the 4 largest hospitals in Boston, Massachusetts, during the w

139 Skin is the largest human organ, and it provides a first line of def

140 Mexican American women exhibited the largest ideal to prehypertension net transition probabil

141 the resolution of climate data will have the largest impact on the accuracy of biological predictions

142 of WD40-repeat (WDR) proteins is one of the largest in eukaryotes, but little is known about their f

143 However, the decrease was largest in low-income patients who resided in expansion

144 Extension is largest in small pores, increasing >10-fold but remainin

145 Volumetric reductions of frontal lobes were largest in the ADHD+ODD group, possibly underlying obser

146 y of schizophrenia in 691 twin pairs was the largest in the field for nearly four decades.

147 iflora, comprising about 500 species, is the largest in the Passion flower family.

148 The urban West showed the largest increase relative to other regions.

149 The largest increase was among older patients (>75 years; n

150 From a regional perspective, we find the largest increases in CyanoHAB occurrence in the Northeas

151 ly 1 day after the procedure, but showed the largest increases of any factor.

152 Yet, which driver exerts the largest influence on ecosystem functioning and whether t

153 Viral-linked cancer had the largest inpatient and outpatient cost impacts per case,

154 The gastrointestinal tract represents the largest interface between the human body and the externa

155 ral effects of CYP11B1 gene mutations in the largest international cohort of 108 patients with steroi

156 This would be the world's largest known example of marine ecosystem "engineering"

157 of the Paleocene-Eocene Thermal Maximum-the largest known greenhouse-gas-driven global warming event

158 Hekou Group of Gansu Province, China has the largest known herbivorous dinosaur teeth.

159 hylogenetic analyses suggest that titin, the largest known protein, first appeared in the common ance

160 As the largest known vertebrates of all time, mysticetes depend

161 (CI) super-eruption (Southern Italy) is the largest known volcanic event in the Mediterranean area.

162 on years ago) extinction event was among the largest known, with 85% species loss [1].

163 l groups on the 2 and 6 positions showed the largest lambdamax for both absorption (635-653 nm) and e

164 performance status (0 v >/= 1), size of the largest lesion (smaller), and KIT mutation (exon 11) wer

165 Maximum size of the largest lesion was </=5 cm in over 75% of cases.

166 e species, for which transport distances are largest, loading seems, counterintuitively, to occur by

167 The largest, longest-lived episodes have the highest inciden

168 The largest mean dissociation scores were found in dissociat

169 because human time scales set a limit on the largest measurable viscosity, and available data are equ

170 t breast, with lesions at 1:00 and 4:00, the largest measuring approximately 3 cm on exam, and multip

171 thorough investigation in the United States' largest medical examiner's office.

172 We conducted the largest meta-analysis of genome-wide association studies

173 e most intense signals were obtained for the largest molecules (>520 g/mol) with low polarity (logP a

174 reasing health benefits (i.e., providing the largest mortality reduction per unit emissions).

175 es may be the optimal strategy to obtain the largest, most highly accurate SNP yield possible from lo

176 s and twins born in 1994-2002 to provide the largest, most population-diverse consideration of this h

177 Colossoma macropomum, or tambaqui, is the largest native Characiform species found in the Amazon a

178 s), focusing primarily on the pairs with the largest native contact surfaces, H1-H2 and H1-H4.

179 inventories from the Amazon floodplain, the largest natural geographic source of CH4 in the tropics,

180 hose from tropical forest soils, the world's largest natural terrestrial N2O source.

181 the smallest neonates to 22.9 degrees in the largest neonates.

182 This enrichment exhibited the largest NH2OH:final product ratio (1.92%), followed by N

183 The first 217 data sets of the largest NOTES registry worldwide-the German NOTES regist

184 The hippocampus has the largest number of differentially expressed genes (DEGs)

185 approximately 1.92 billion short reads, the largest number of differentially expressed genes (DEGs)

186 the northwestward shift was observed in the largest number of species (n = 13).

187 The largest observed earthquakes occur on subduction interfa

188 yotes and prokaryotes, and they comprise the largest of all of the peptidase families, their dynamic

189 The largest of these regions are enriched for genes involved

190 The turkey vulture has the largest olfactory bulbs in absolute terms and adjusted f

191 of atmospheric carbon dioxide (CO2) was the largest on record.

192 arsenic concentrations is one of the world's largest ongoing natural disasters.

193 ton absorption edge, representing one of the largest optical parametric gains to date on a CMOS platf

194 The skin is the largest organ in the human body and provides the first l

195 A Bayesian method identified the largest p-value threshold (q = .025) associated with twi

196 due to fossil sources, which contribute the largest part to organic carbon (OC, 67 +/- 3%) and its s

197 This pooled analysis includes 1 of the largest patient-level data sets on treatment of DME with

198 icea glauca, Pinaceae), which has one of the largest plant genomes (20 Gbp).

199 The largest point estimates were found for the exposure iden

200 With these data we constructed the largest pollinator importance network to date and compar

201 show that in rats, genetic silencing of the largest population of brainstem vagal preganglionic neur

202 urons) in the periaqueductal gray (PAG), the largest population of LepRb neurons in the brain stem, m

203 The West Antarctic Ice Sheet is one of the largest potential sources of rising sea levels.

204 lose to the cortical surface (< 400 mum) the largest pressure drop takes place in the capillaries (37

205 Brazil stands out as the largest producer of crystal sugar in the world, exportin

206 wells were drilled, completed, and had their largest production volumes.

207 The largest products formed in these experiments at near-amb

208 Body mass index explained the largest proportion of AF risk.

209 erebellar cognitive areas are reached by the largest proportion of the reconstructed CPC, supporting

210 The largest proportion of the variance explained by any biom

211 ABC transporters form one of the largest protein superfamilies in all domains of life, ca

212 action vs. a decentralized model through the largest provenance database available to date in the reg

213 from the Veterans Health Administration, the largest provider of liver-related health care in the Uni

214 project (HMP) dataset, currently one of the largest published microbial 16S rRNA sequence dataset.

215 plying a 42% threshold (method 5) led to the largest quantification errors (xSPECT, 32.3%; Flash3D, 4

216 proportion (94%) of the allergome, with the largest quantities of the minor Amb a 4 and major Amb a

217 domization (MR), using summary data from the largest RA and AD Genome Wide Association (GWA) and meta

218 NTERPRETATION: To our knowledge, this is the largest randomised controlled trial of a psychological i

219 nadian Cancer Trials Group study HN.6 is the largest randomized clinical trial to date comparing the

220 Data were sourced from Scotland's largest red meat abattoir throughout 2013 and 2014.

221 t the 10-y follow-up, men and women with the largest reductions in energy intake had lost 7.3% and 3.

222 lateral boundary conditions that lead to the largest reductions in modeled surface O3 concentrations.

223 The largest relative rate increases were seen for regional,

224 The largest relative risk was observed for the land-use regr

225 g level, and the sample with x = 0.3 has the largest remanent magnetization and the smallest polariza

226 Here we analyze the sequence of the largest repeat in EBV (IR1).

227 This study describes the largest reported cohort of patients with renal disease i

228 We conducted a retrospective analysis of the largest reported cohort, consisting of 182 patients with

229 UK Biobank is the world's largest repository for phenotypic and genotypic informat

230 aders of the Athabasca Bituminous Sands, the largest reservoir of bitumen in the world.

231 For the control group without templates, the largest RMSDs were 2.63 mm in superoinferior direction a

232 India has the world's largest ruminant population and produces 20% of the wo

233 Here, we show using the largest sample of paternity data available that, contrar

234 In the largest sample to date, lower Glu and elevated Gln/Glu l

235 We examine the short-term effects of the largest-scale policy shift, California's Assembly Bill 6

236 In the largest screening of CD in the United States to date out

237 r delineate its optimal use, we describe the largest series of kidney transplant recipients treated w

238 This is the largest series of VP shunt infections in adults reported

239 per bloodstream infection accounted for the largest share of the total costs in each group and was a

240 are the populations that have undergone the largest shifts in OD.

241 One of the largest single sources of epilepsy in the world is produ

242 isorders, we have diagnosed and followed the largest single worldwide cohort of 36 AME patients.

243 keratoprosthesis type II implantation in the largest single-center case series with the longest avera

244 now clear that the environment is the single largest source and reservoir of resistance.

245 The largest source of damages was road flooding caused by in

246 ust aerosols are responsible for some of the largest sources of uncertainties in our current understa

247 Here we report the largest Southern Hemisphere network of annually resolved

248 (CH4) requires days of integration time with largest space telescopes, and thus are very challenging

249 The largest standard deviations of age-standardised DALYs be

250 kDa and a diameter of 4.5 nm, making it the largest, structurally characterized M2nLn complex descri

251 To our knowledge, this is the largest study ever conducted on this topic, and using th

252 This is the largest study on the cognitive phenotypes of CNVs to dat

253 er ranged from 5% to 36% at 1 year, with the largest study reporting an 11% surgery rate and 1% compl

254 This is the largest study to date of antibacterial prophylaxis durin

255 In the largest study to date, we compare 22q11DS to ND in comor

256 tions by mass spectrometry revealed that the largest subcomplex (IIa) represents the succinate dehydr

257 d 496 genera) representing all 13 classes of largest subphylum of Fungi-Pezizomycotina (Ascomycota)-b

258 ve tetralogy of Fallot (TOF), comprising the largest subset of severe congenital heart disease in the

259 HD finger transcription factor (BPTF) is the largest subunit of nucleosome remodeling factor (NURF),

260 The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrat

261 cation of the C-terminal domain (CTD) of the largest subunit of RNA polymerase II.

262 ers responded to our survey, making this the largest survey of academic surgeons to date.

263 These results, based on the largest systematic sampling of amphibian malformations,

264 ding to DM status and therapy in the world's largest TAVR registry.

265 Globally, drylands represent the largest terrestrial biome and are projected to expand by

266 Trees represent the largest terrestrial carbon sink and a renewable source o

267 Soils account for the largest terrestrial pool of carbon and have the potentia

268 triggered by the extirpation of Australia's largest terrestrial predator, the dingo (Canis dingo), c

269 nes of GPS-tagged individuals of the world's largest terrestrial soaring scavenger, the Andean condor

270 rest, the core function of the pulvinar, the largest thalamic complex in primates, remains elusive.

271 cetacean, the vaquita, at 1.4 meters and the largest, the blue whale, reaching 33 meters.

272 suggest that drought will continue to be the largest threat to US rainfed maize production under RCP4

273 We constructed the largest time-calibrated phylogeny for the subfamily to d

274 Our study is the largest to date affirming that best practices can preven

275 he West African Ebola virus epidemic was the largest to date, with more than 28,000 people infected.

276 In this study, we use the largest-to-date set of laboratory-generated and simulate

277 oup analyses showed that diets providing the largest total energy intake and energy exchange enhanced

278 on (DSi) carried by effluent from the second largest treatment plant by flow in the United States (De

279 : This study, which is to our knowledge, the largest trial of CIDP to date and the first to study two

280 The median largest tumor diameter was 4.0 cm (range, 3.3-5.0 cm).

281 2.81 [1.72-4.42]; p=0.0004), diameter of the largest tumour (1.07 per cm increase [1.04-1.11]; p<0.00

282 e that an unclosed energy balance caused the largest uncertainties, in particular if it was associate

283 16 uranium nodes and 816 organic linkers-the largest unit cell found to date for any nonbiological ma

284 30-km(2) area of Oakland, CA, developing the largest urban air quality data set of its type.

285 1 at 100 K, to the best of our knowledge the largest value known to date.

286 .202 nm with a corresponding Q of 5,603, the largest value reported for a TMD laser.

287 Medicare Shared Savings Program (MSSP), the largest value-based reimbursement program in U.S.

288 While the largest variances in the latitudinal and longitudinal WP

289 ted with annual and seasonal timescales, the largest variances in the WPV and HC are due to the multi

290 These are by far the largest variant peptides resolved by any method, some wi

291 , microvascular invasion, and the sum of the largest viable tumor and number of tumors on explant.

292 teria roenbergensis virus (CroV), one of the largest viruses analyzed by cryo-electron microscopy (cr

293 The largest volcanic emitters outgas carbon with higher delt

294 in its history.Mars hosts the solar system's largest volcanoes, but their formation rates remain poor

295 h the range in pressure between smallest and largest waist circumference being 15 mmHg.

296 were retrieved from Weather Underground, the largest weather database available online.

297 The effect is largest when the fitness values of the mutants and wild

298 ed potentials by spinal cord stimulation was largest when the spinal electrodes were placed over the

299 d the decrease in transition temperature the largest, when the alcohol partitions equally between the

300 m a longitudinal multi-omics analysis of the largest yet-reported cohort of melanoma patients reveal