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3 o 80 years of age with osteoporosis received lasofoxifene 0.25 mg/d, lasofoxifene 0.5 mg/d, or placeb
4 In postmenopausal women with osteoporosis, lasofoxifene 0.5 mg/d for 5 years reduced the risk of CH
5 asofoxifene (PEARL) trial, women assigned to lasofoxifene 0.5 mg/d had a lower risk of major coronary
7 D events, and evaluate whether the effect of lasofoxifene 0.5 mg/d is consistent across different cat
9 ificant reduction in risk of CHD events with lasofoxifene 0.5 mg/d was due primarily to lower risks o
13 d ratios were <1.0, no significant effect of lasofoxifene at 0.5 mg/d was demonstrated for coronary d
15 In postmenopausal women with osteoporosis, lasofoxifene at a dose of 0.5 mg per day was associated
17 femoral neck or spine to receive once-daily lasofoxifene (at a dose of either 0.25 mg or 0.5 mg) or
19 in the placebo group, 7.0 in the lower-dose lasofoxifene group, and 5.7 in the higher-dose lasofoxif
20 e placebo group, two women in the lower-dose lasofoxifene group, and two women in the higher-dose las
24 novel selective estrogen receptor modulator lasofoxifene (LAS) to inhibit the development of mammary
26 enopausal Evaluation and Risk Reduction With Lasofoxifene (PEARL) trial, women assigned to lasofoxife
27 ERMs; tamoxifen, raloxifene, arzoxifene, and lasofoxifene) with placebo, or in one study with tamoxif
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