ライフサイエンスコーパス: later stage of

1 ize the need to evaluate their roles through later stages of a tree's life cycle.

2 During the later stages of a trial, the motor imagery for a particu

3 rly disseminated Lyme disease but not in the later stages of active infection.

4 e/tissue repair responses prevail during the later stages of acute liver failure where elevated level

5 a protective and reconstructive way even in later stages of AD.

6 he dorsal striatum, a region associated with later stages of addiction, craving, and cue-induced rela

7 The role of lipins at later stages of adipogenesis, when cells initiate the fo

8 initial phases of activation and during the later stages of aggregation.

9 y shifted the lag time with little effect on later stages of aggregation.

10 of Th2 immune responses, whereas its role at later stages of allergic disease may not be as critical

11 AL2 acts independently of VPS33B/VPS16B at a later stage of alpha-granule biogenesis.

12 In the later stages of ALS, pain can be severe enough to requir

13 ntly of amyloid pathology, especially in the later stages of Alzheimer's disease.

14 Coinhibitory pathways are thought to act in later stages of an adaptive immune response, but whether

15 d that VvMYBA is a positive regulator of the later stages of anthocyanin synthesis, modification, and

16 OM acts early, whereas BIG ARF-GEFs act at a later stage of apical hook development.

17 BamA and therefore appeared to function at a later stage of assembly.

18 It was not possible to assess later stages of atherosclerosis because of increased mor

19 Loss of LAPTM4B also inhibited later stages of autophagy by blocking maturation of the

20 Here, we identify that mTORC1 inhibits later stages of autophagy by phosphorylating UVRAG.

21 in signaling in sensory neurons to mediate a later stage of axon development - arborization in the ta

22 ate motoneuron development, particularly the later stages of axon branch and dendrite formation.

23 ent on the Nox2 isoform of NADPH oxidase, at later stages of B cell activation (6-24 h) ROS were gene

24 lar sources and plays a critical role at the later stages of B cell activation by promoting sustained

25 In the chicken bursa, the later stages of B cell development occur in the presence

26 reveals selective TACI haploinsufficiency at later stages of B-cell development.

27 GSH synthesis falls during later stages of BDL due to lower expression of GSH synth

28 ent to catheter biomaterials, and defects in later stages of biofilm development were indicated.

29 At later stages of blood flow, Foxc2 and calcineurin-Nfat s

30 However, their role in later stages of brain development, particularly in the r

31 olonization, the role of BCR ligation in the later stages of bursal B cell lymphopoiesis remains elus

32 A similar analysis of later stages of C. elegans development has been challeng

33 ediately after stimulus onset, followed by a later stage of category-specific perceptual processing.

34 nt to the active cluster and of the early to later stage of cell cycle, with marked increase in expre

35 It was also observed that mAbs harvested at later stages of cell culture contained higher concentrat

36 cation within the septal aperture during the later stages of cell division.

37 istent with the actions of ampicillin on the later stages of cell wall biosynthesis.

38 Blocking NMDA receptors during later stages of circuit development did not disrupt segr

39 Patients with later stages of CKD had lower renal elasticity values, i

40 try inhibitors, with a focus on drugs in the later stages of clinical development.

41 ly show promising results in rodents fail in later stages of clinical trials.

42 By contrast, at later stages of clone growth, clones change their growth

43 lly accommodates only smaller sample sets at later stages of clone selection.

44 ependent excessive cell proliferation in the later stages of collateral remodeling correlates with im

45 However, analysis of Lhx2 function at later stages of cortical development has been hampered b

46 At later stages of cytokinesis, these various rings appeare

47 nd the neural correlates associated with the later stages of decision making (e.g., motor response ge

48 of hippocampal atrophy is well known in the later stages of decline, the ability of fornix-hippocamp

49 ating that Trps1 functions as a repressor of later stages of dentinogenesis, we provide functional si

50 s rapid gene expression and functions at the later stages of development and differentiation.

51 Loss of Hand2 at later stages of development and in restricted domains of

52 te synaptic plasticity and brain function in later stages of development and in the mature organism.

53 In addition, later stages of development and the timing of emergence

54 h in-depth phenotyping of the fourth leaf at later stages of development in 197 recombinant inbred li

55 ides with carotenoid accumulation during the later stages of development of underground storage roots

56 anglion cells, whereas cells from earlier or later stages of development or from other tissue sources

57 nterestingly, ablation of Mef2 expression at later stages of development showed MEF2 to be more dispe

58 At later stages of development the expression of Semaphorin

59 that express both Pax6 and Gsx2, but during later stages of development this boundary is largely ref

60 At later stages of development, activation of Notch in nons

61 At later stages of development, kcnj1 appeared in cells of

62 At later stages of development, Notch signaling is proposed

63 At later stages of development, PGE2 acting via the ep4a re

64 However, during later stages of development, smad2 and smad3 became stro

65 expected downregulation of pax2a and pax8 at later stages of development, suggesting complex regulato

66 eterogeneous range of migratory behaviors at later stages of development, with the acquisition of com

67 ng endoderm with complete epithelial loss at later stages of development.

68 pines, but little is known about its role in later stages of development.

69 mplantation lethality, preventing studies at later stages of development.

70 sequence, result in morphological defects at later stages of development.

71 as well as the stability of Mdm2 and p53 at later stages of development.

72 noted within misshapen cartilage elements at later stages of development.

73 y is unchanged at the onset but decreases at later stages of diabetes.

74 y increased chitin production that occurs in later stages of diatom growth.

75 nished in tumors derived from B cells at the later stages of differentiation (with complete loss in P

76 further study into the mechanisms governing later stages of differentiation and the acquisition of f

77 that although fusion oncogene expression in later stages of differentiation can transform mesenchyma

78 In addition to Dlx6's expression at later stages of differentiation of many basal ganglia nu

79 that kif3c, although redundant with kif3b at later stages of differentiation, is not active early in

80 effects are not observed in adult B cells in later stages of differentiation.

81 umors (P = 0.037) and remained stable in the later stages of disease (i.e., 16 weeks old with large t

82 At moderate and later stages of disease (LMCI/AD), hypometabolism become

83 strategies for secondary prevention aimed at later stages of disease are also needed.

84 tabolic dysfunction is often observed in the later stages of disease progression and is associated wi

85 pression of IL-13Ralpha2 was associated with later stages of disease progression and poor outcome in

86 ed inhibition causes more severe myopathy at later stages of disease progression potentially through

87 s to most people remaining undiagnosed until later stages of disease when prognosis is poor and treat

88 erebral malaria, but it is less effective in later stages of disease when the host inflammatory respo

89 aggravated disease course, especially in the later stages of disease, but also importantly resulted i

90 ally affects the cortical regions during the later stages of disease, with neuronal loss, gliosis, an

91 e of gene profiles unique to the initial and later stages of disease.

92 ons are the major causes of exacerbations in later stages of disease.

93 in contrast, relatively well preserved until later stages of disease.

94 to independently drive neuroinflammation at later stages of disease.

95 xpression were also found to decrease during later stages of EBV lytic replication in EBV-infected ly

96 n of DGK decreased PA production only at the later stages of EGF stimulation, suggesting that PLD2 pr

97 ypass translational arrest can be stopped at later stages of elongation while translation of some pro

98 stages, and then TET1 is a key regulator at later stages of embryo development.

99 for primordial germ cell development during later stages of embryogenesis, is essential for Xenopus

100 During later stages of embryogenesis, Prox1 appears to regulate

101 increased cardiomyocyte proliferation during later stages of embryogenesis.

102 extracellular calcite-protein composites) at later stages of embryonic development.

103 at the mutation causes aberrant movements in later stages of endocytosis, consistent with a scission

104 uilliform body plan is gradually lost during later stages of evolution, gaits are evolved for the fin

105 ediated sugar release was predominant in the later stages of fermentation, which explains why higher

106 e to detect both glucose and fructose in the later stages of fermentation, while HPLC was not.

107 longating fibers but was degraded during the later stages of fiber differentiation.

108 ction of small oligomers is still present at later stages of fibril assembly.

109 , and thus oil accumulation, correlates with later stages of fruit expansion.

110 ht on the role of oxidative processes in the later stages of fruit ripening.

111 chanisms of accumulation of ascorbate in the later stages of fruit ripening.

112 tion of a transcription factor essential for later stages of gametogenesis extends the replicative li

113 At later stages of GE, unreacted Ag inclusions phase segreg

114 These nucleosomes reassemble at later stages of gene expression.

115 sis, and conditional inactivation of ldb1 at later stages of gestation and in adult mice demonstrated

116 term: our data lead us to speculate that at later stages of gestation SNAT1 and/or SNAT2 are more im

117 ome susceptible to ZIKV infection as well at later stages of gestation.

118 itment and mobilization were impaired at the later stage of GSIS.

119 interferon-stimulated genes observed during later stages of hantavirus infection fail to combat the

120 ardial cushion development, but its roles in later stages of heart valve maturation and homeostasis h

121 of DNA modification and transcription in the later stages of human life.

122 ease in myofiber DNA content observed at the later stage of hypertrophy was associated with a signifi

123 erbating these changes are documented during later stages of hypertrophy (usually termed pathological

124 f LSD1, causing HIF-1alpha downregulation in later stages of hypoxia.

125 ity of oligodendrocytes and/or astrocytes at later stages of illness.

126 ntiation of imINPs due to loss of Earmuff at later stages of imINP development.

127 Of interest was that during later stages of induced leukocyte apoptosis, soluble L-s

128 and this protective effect was preserved at later stages of infarct development.

129 This protective effect was preserved at later stages of infarction as well as in elderly mice.

130 This protective effect was preserved at later stages of infarctions as well as after permanent s

131 tachyzoite growth in their brains during the later stage of infection, were infected, and one group r

132 but switched to amyloid-like structures at a later stage of infection.

133 came strongly biased for positive strands at later stages of infection in RVI-compromised flies due t

134 cally and that much of the damage during the later stages of infection is due to the interactions of

135 of infection, these results suggest that at later stages of infection, PCA present in infected tissu

136 regulated by SA and JA during the early and later stages of infection, respectively.

137 was sensitive to ACC1 inhibition even at the later stages of infection, suggesting a late role for fa

138 Here, we describe later stages of infection, the ensuing inflammatory resp

139 nt postexposure treatments are inadequate at later stages of infection, when high levels of anthrax t

140 igh-density intracellular replication during later stages of infection, when the wild-type strain con

141 y inhibited mTOR-regulated autophagy even at later stages of infection, whereas there was a clear ind

142 xhibited impaired bacterial clearance during later stages of infection, which was associated with alt

143 ey developed significantly larger lesions at later stages of infection, with a more pronounced inflam

144 At early but not at later stages of infection, WT mice had higher circulator

145 immune dysfunction and viral persistence at later stages of infection.

146 tes with anti-inflammatory/M2 macrophages at later stages of infection.

147 ater, probably to prevent suppression during later stages of infection.

148 However, they could affect pathogenesis at later stages of infection.

149 d significantly more severe pathology in the later stages of infection.

150 iption and replication at early and possibly later stages of infection.

151 pillover into the downstream LNs involved at later stages of infection.

152 inhibited IFITM protein accumulation in the later stages of infection.

153 At later stages of infiltration, T-cell motility accelerate

154 e increased accumulation observed during the later stages of inflammation.

155 RNAP exit kinetics from complexes stalled at later stages of initiation (e.g., from a 7-base transcri

156 At later stages of kernel development, most of the free lys

157 more marked repression of growth during the later stage of leaf development.

158 r expression pattern and function diverge at later stages of leaf development.

159 learned the skill; continued practice during later stages of learning (i.e., after motor kinematics h

160 rebellar excitability (CBI) changes, whereas later stages of learning will result in M1 LTP-like plas

161 ific in their temporal structure compared to later stages of learning.

162 O1 and Sp1 formed complexes during early and later stages of lens development.

163 elopment and functions, particularly, at the later stages of life.

164 paradoxically, changes to convergence in the later stages of life.

165 an increase of C/EBPbeta-HDAC1 complexes at later stages of liver cancer.

166 tanding of the molecular action of LeTx at a later stage of low-dose exposure.

167 During later stages of lymphatic development, we observed an in

168 d downregulation of MHC-I was evident during later stages of lytic replication.

169 ave a significant therapeutic impact even at later stages of mammary tumor progression.

170 (HSP70) is constitutively expressed and, at later stages of maturation, translocates into the nucleu

171 s a transient activation of caspase-3 at the later stages of maturation.

172 that curtail their colocalization during the later stages of maturation.

173 G2(+) cells may reflect analysis of cells in later stages of maturation.

174 , and lactate decreased significantly at the later stages of meal challenge in RYGB surgery subjects

175 nes DAZ and BOULE (also called BOLL) promote later stages of meiosis and development of haploid gamet

176 ing step of cancer metastasis and MET in the later stage of metastasis during breast cancer progressi

177 Their work shows that the later stages of metastasis can be influenced by transien

178 ntially facilitating earlier, but repressing later, stages of metastasis by regulating an EMT-MET axi

179 ng reveals that rosette renewal fails during later stages of migration.

180 During later stages of mitosis, p-Moesin localization shifts mo

181 regulation of cortical contractility in the later stages of mitosis.

182 Previously, the later stages of monkeypox infection were defined, but th

183 ch indicated that the defect occurred during later stages of monocyte development.

184 rom bone marrow, the contribution of CCR2 to later stages of monocyte recruitment remains unresolved.

185 At the later stages of MS and experimental autoimmune encephali

186 In later stages of MS, phase rim lesions continue to smolde

187 male patients' accelerated disease course at later stages of MS.

188 At later stages of myelination, Scribble acts to negatively

189 in the number of apoptotic cells during the later stages of myelinogenesis were observed.

190 MPN patients, which occurs in both early and later stages of myeloid differentiation.

191 he REP domain is not required in vivo during later stages of myogenesis, even though Twi activity is

192 ices from 2 month old mhAPP mice, whereas at later stage of neurodegeneration (6 month) basal synapti

193 First, during the later stages of neurogenesis (P18), neurons make up most

194 development of sensory neurons in Xenopus at later stages of neurogenesis and this can be rescued by

195 ency of cortical plate-directed migration at later stages of neurogenesis concomitant with the start

196 omomeric nAChRs appear to be involved in the later stages of nicotine dependence.

197 nt for mucosal immunity, whereas earlier and later stages of NK developmental intermediates do not ex

198 differentially expressed, especially at the later stages of nodule development when active nitrogen

199 e mandiblar stylets become more prominent in later stages of nymphal development, while odontoid prot

200 nt metabolic capabilities, especially during later stages of nymphal feeding.

201 ding reduction in craniofacial plasticity at later stages of ontogeny.

202 riking contrast, the absence of dTBCB during later stages of oogenesis causes major defects in cell p

203 ntrast, Lef1DeltaN is only detectable in the later stages of osteoblast differentiation and promotes

204 in but does not induce genes associated with later stages of osteogenesis.

205 However, its function at later stages of pancreatic carcinogenesis remains poorly

206 During later stages of pancreatitis, C5-deficient mice and mice

207 rnal scaffolding protein, which mediates the later stages of particle morphogenesis, restored viabili

208 (PI3K)/AKT signaling axis is dysregulated in later stages of PDAC.

209 SHIP-1 deficiency also altered later stages of phagosome maturation, as indicated by th

210 Recently duplicated genes are utilized at later stages of placentation to meet the metabolic needs

211 n activity, and to maintain this activity at later stages of placode development.

212 but is necessary for proto-NM renewal during later stages of pLL formation.

213 tively high yield whereas none are formed at later stages of polymerization.

214 transcription was markedly repressed in the later stages of pregnancy and immediately recovered afte

215 /d [DOSAGE ERROR CORRECTED] for those in the later stages of pregnancy or lactating can be supported.

216 l infections may disrupt fetal protection in later stages of pregnancy.

217 s are prevented from reaching awareness at a later stage of processing.

218 riptional activity are often observed in the later stages of prostate cancer.

219 ild-type Arabidopsis, suggesting problems in later stages of PsaA/B protein expression in the two var

220 tion, but it is assumed to be minimal before later stages of puberty.

221 During the later stage of reactor operation, higher expression of a

222 at stargazin affects AMPA-R trafficking at a later stage of receptor maturation.

223 f proliferation but governs proliferation at later stages of regeneration.

224 ombine with targeted therapies impacting the later stages of remodeling and vessel maturation are exp

225 ly kidney development, but their role during later stages of renal tubule maturation is not well unde

226 ne all increased dramatically, especially at later stage of ripening, whereas the changes for alpha-i

227 tion, PAR2 was upregulated especially at the later stage of RSV infection.

228 t exogenous and endogenous substrates during later stages of SE.

229 However, the later stages of segment patterning, regulated by the "pa

230 ry input is integrated during both early and later stages of sensory information processing, mainly o

231 e cus2 mutant, but are lost progressively at later stages of sepal development, indicating that CUS2

232 t nitric oxide synthase 2 levels decrease in later stages of sepsis, whereas levels and activity of s

233 At later stages of septum formation, GFP-MinD often paused

234 tent with the specific expression of AMD1 at later stages of sexual development.

235 Later stages of spectral evolution are consistent with h

236 Barlow's proposal that the ganglion cell and later stages of spiking neurons transfer information ess

237 H4S1ph and H4ac co-exist globally during later stages of sporulation, in contrast to DSB repair.

238 fields, and these fields might survive into later stages of stellar evolution, but information has b

239 sing within the somatosensory network in the later stages of stimulus processing.

240 e receptor signaling, LPL is critical to the later stages of synapse maturation and cellular polariza

241 sponse is instrumental in the development of later stages of syphilis.

242 Moreover, alterations in H2A.Z binding at later stages of systems consolidation suggest that this

243 nding to the ribozyme but instead forms at a later stage of the catalytic cycle.

244 -kDa FK506-binding protein), which acts at a later stage of the chaperone cycle.

245 rent treatment, especially when initiated at later stage of the disease, does not produce completely

246 improved motor function of mdx mice at that later stage of the disease.

247 substantia nigra and cause parkinsonism at a later stage of the disease.

248 e effects of CHL have been mainly studied at later stages of the auditory pathway, but early stages r

249 hearing loss could cause similar changes at later stages of the auditory pathway, which could contri

250 However, they showed severe defects in later stages of the biogenesis process, presumably durin

251 to provide vital repolarizing current during later stages of the cardiac action potential.

252 is removed by the sirtuins Hst3 and Hst4 at later stages of the cell cycle.

253 newly synthesized CENP-A is deposited during later stages of the cell cycle.

254 ition of the stress and was not required for later stages of the cell death program.

255 At the later stages of the disease ambulation often becomes dif

256 Later stages of the disease are characterized by inflamm

257 could inhibit allergic responses during the later stages of the disease process, namely allergen re-

258 iorgan donors with T1D (both at onset and at later stages of the disease) and not in that of multiorg

259 Current therapies for DR address only the later stages of the disease, are invasive, and have limi

260 gates of mutant SOD1 occurs primarily in the later stages of the disease, concurrent with the appeara

261 on; (c) higher fitness clones are present in later stages of the disease, indicating a progressive cl

262 In later stages of the disease, the pathology extends to th

263 beta will have major clinical effects in the later stages of the disease.

264 in early cancer development rather than the later stages of the disease.

265 ry phenotype would be most beneficial in the later stages of the disease.

266 ading to lymphatic contraction arrest at the later stages of the disease.

267 r had an increasingly negative impact in the later stages of the disorder.

268 VEP amplitude that was most striking in the later stages of the disorder.

269 phase of recycling and this has an impact on later stages of the endo-exocytic pathway.

270 in the transfer of Pse onto flagellin at the later stages of the glycosylation pathway.

271 C-terminal half of IE2 86, are important for later stages of the infection.

272 ution in introduced ranges is a mechanism at later stages of the invasion process, the introduction o

273 an active role for this molecule in driving later stages of the multistep adhesion cascade.

274 ively few clues concerning the nature of the later stages of the pathway.

275 While the later stages of the pathways are well elucidated, the mo

276 ate chemistry becomes less active during the later stages of the pollution episodes.

277 scle-derived stem cells is obtained from the later stages of the process.

278 Yet signaling pathways that regulate later stages of the productive gammaherpesvirus replicat

279 e RS domain destined to be phosphorylated at later stages of the reaction docks to a kinase groove di

280 To permit examination of later stages of the reaction sequence to 2, the (15)N-la

281 tigated the fate of pre-RC components during later stages of the reaction.

282 ation to support fatty acid synthesis in the later stages of the stress response.

283 ssion facilitates DNA replication and allows later stages of the viral life cycle to proceed in the a

284 ional enhancement builds up at progressively later stages of the visual hierarchy.

285 ly stages of the cell cycle, or large and in later stages of their cell cycle.

286 tatic interactions both in the early and the later stages of this model coupled folding and binding p

287 gions previously shown to be demyelinated in later stages of this syndrome.

288 portant role for the adapter protein ShcA in later stages of thymic T cell development and in periphe

289 Later stages of tooth development were characterized by

290 , because Pitx2 is also a major regulator of later stages of tooth development, especially during ame

291 significant increases in methanogens at the later stages of treatment that correlated with increases

292 frequently if they play functional roles in later stages of tumor development, such as metastasis.

293 nction during astroglial immortalization vs. later stages of tumor development.

294 proteins such as DNA-PK and CHK1 during the later stages of tumor development.

295 ed prior to cancer onset, suggesting that at later stages of tumor progression GSH becomes dispensabl

296 hrough immunosurveillance while facilitating later stages of tumor progression.

297 vascularization or burden when initiated at later stages of tumor progression.

298 entry, whereas lower concentrations block a later stage of virus life cycle.

299 from the nucleus to the cytoplasm during the later stages of virus replication.

300 nd is therefore thought to be generated at a later stage of visual processing [6].