ライフサイエンスコーパス: laterality

1 hways involved in the early establishment of laterality.

2 crimination, floating in water, and whisking laterality.

3 lumen expansion leading to defects in organ laterality.

4 the unaffected right hemisphere) on language laterality.

5 motility leads to coordinated but randomized laterality.

6 eral plate mesoderm for the establishment of laterality.

7 brospinal fluid circulation and establishing laterality.

8 ed L-R patterning as well as cardiac and gut laterality.

9 chymal position, location in the kidney, and laterality.

10 study factors involved with birth defects in laterality.

11 after the 32-cell stage exhibited randomized laterality.

12 donor sex, body mass index, and donor kidney laterality.

13 nsible for inducing and maintaining neuronal laterality.

14 of integrins to the regulation of vertebrate laterality.

15 ts Pitx2c expression and results in abnormal laterality.

16 he signals that lead to the establishment of laterality.

17 neuroanatomical asymmetries with consistent laterality.

18 mpound that affected both body curvature and laterality.

19 hanism for the known effects of serotonin on laterality.

20 or the regulation of both heart and visceral laterality.

21 is a broadly conserved mechanism to achieve laterality.

22 loping gut; as such, it only regulates heart laterality.

23 of asymmetrical genes, and randomized organ laterality.

24 in ectopic nuclear beta-catenin and altered laterality.

25 ppfer's Vesicle (KV) have been implicated in laterality.

26 ts and trans-acting factors that control ASE laterality.

27 nd result in subsequent alterations to organ laterality.

28 rences in ocular anatomy relating to sex and laterality.

29 arollia in varying degrees of prominence and laterality.

30 s projecting within the cortex have unbiased laterality.

31 regions with pathologic results, respecting laterality.

32 ented with individual, but not species-wide, laterality.

33 nstrate meaningful thresholds in classifying laterality.

34 etric and provides a good predictor of organ laterality.

35 lower respiratory infections and defects in laterality.

36 d found that eye dominance does predict tool laterality across individuals.

37 nt and often less-than accurate estimates of laterality across various MEG studies.

38 ile those of patients with atypical language laterality also included non-classical language areas su

39 sents a more broadly conserved mechanism for laterality among amniotes than had been previously belie

40 racterized along several dimensions: course, laterality, anatomic location of the inflammation, morph

41 ipulation of node Ca(i)(2+) randomized heart laterality and affected nodal expression.

42 ctors interferes with establishment of organ laterality and causes defective cilia formation in Kupff

43 os targeting dyx1c1 in zebrafish also caused laterality and ciliary motility defects.

44 ory obstructive disease with randomized body laterality and infertility, resulting from cilia and spe

45 se data provide new insights into vertebrate laterality and offer the zebrafish ace/fgf8 mutant as a

46 over a novel role for RA in regulating organ laterality and provide an animal model of one form of hu

47 mechanism for establishment of correct brain laterality and provide an entry point to understanding t

48 Unbiased stereological methods revealed laterality and sex differences in MePD astrocyte number

49 d dominant negative CaMK-II, randomize organ laterality and southpaw (spaw) expression in lateral pla

50 is contrasts with humans' species-wide motor laterality and uncorrelated motor-visual laterality, pos

51 nated as "undifferentiated" with the course, laterality, and anatomic location (eg, undifferentiated

52 Age, central corneal thickness, laterality, and glaucoma and lens status did not impact

53 cts (CHDs), left-right disturbances (L-R) or laterality, and holoprosencephaly (HPE).

54 athway that are clearly associated with CHD, laterality, and HPE.

55 tware and were adjusted for age, sex, manual laterality, and National Institutes of Health Stroke Sev

56 ng bilateral visceral organ asymmetry, brain laterality, and ocular dominance.

57 lia at the left-right organizer to determine laterality, and reveal a novel mechanism for human heter

58 udying the effects of reconstructive method, laterality, and risk factors on surgical complication ra

59 odel was used to analyze eye, nasal/temporal laterality, and SC area on or off SC/CC.

60 uch as cleft completeness or incompleteness, laterality, and the presence of dental anomalies to asse

61 The mechanistic basis for the laterality anomalies in Cx43.4-deficient embryos is a pr

62 Age-related reductions in laterality are a widely debated topic and their origins

63 very few molecular correlates to functional laterality are known.

64 ar and cellular mechanisms controlling organ laterality are not well understood.

65 er and angle variables with consideration of laterality as the random effect and pupil diameter as th

66 n an unselected sample of the population and laterality assessment using coarse functional transcrani

67 Analyses were stratified by disease laterality at randomization (31 unilateral vs 224 bilate

68 tries can exhibit either random or invariant laterality at the population level.

69 To explore differences in laterality based on disease characteristics and outcomes

70 This laterality bias is due to left-sided Nodal signaling and

71 alateral], and 16 of unknown invasiveness or laterality) breast cancers were diagnosed.

72 lomic pouch morphogenesis and institution of laterality, but does not directly affect foxY transcript

73 cancers incorporate lymph node (LN) size and laterality, but place less weight on the total number of

74 c criterion of SCPN (including number, size, laterality, calcification, or contour) was associated wi

75 lateralized, although the direction of this laterality can vary for different tasks (e.g. foraging o

76 In addition, the laterality change of the functional activation is negati

77 not correlated significantly to age, gender, laterality, clinical appearance or focality of the tumor

78 onent maps in patients with typical language laterality consistently included classic language areas

79 Response laterality (contralateral vs. ipsilateral) was analysed

80 were strongly contralateral but the response laterality decreased and then disappeared for later peak

81 the expense of immotile cilia and produces a laterality defect reminiscent of loss of the ciliary sen

82 A results in a reversal of the somitogenesis laterality defect.

83 cyte cell lineages were traced in normal and laterality defective embryos of the frog, Xenopus laevis

84 ineages and Pitx2c expression are altered in laterality defective embryos; and (3) abnormal LR cardia

85 gnificance by analysing 187 individuals with laterality defects (heterotaxy) that were associated wit

86 l Birth Defects Prevention Study but without laterality defects (n = 17, 6%).

87 Group 3 was syndromic, with laterality defects (n = 30, 10%).

88 ey cyst formation is closely associated with laterality defects and body curvature.

89 NPHP4 mutations are associated with cardiac laterality defects and heterotaxy.

90 der characterized by chronic airway disease, laterality defects and male infertility.

91 fat diet more than doubles the penetrance of laterality defects and, surprisingly, induces palatal cl

92 Loss of rargb causes biliary and organ laterality defects as well as asplenia, paralleling symp

93 spb7 is expressed; knockdown of hspb7 causes laterality defects by disrupting the motility of these c

94 heart structure, demonstrating that cardiac laterality defects can occur even in instances of otherw

95 ered that loss of bbs8 and vangl2 results in laterality defects due to cilia disruption at the KV.

96 de linkage analysis in patients with cardiac laterality defects from a consanguineous family.

97 ads to oto-sino-pulmonary diseases and organ laterality defects in approximately 50% of cases.

98 The genetic causes of laterality defects in humans are highly heterogeneous.

99 ur understanding of genetic contributions to laterality defects in humans.

100 n and its loss of function is known to cause laterality defects in mouse and medaka fish models.

101 the left LPM is a potential cause of cardiac/laterality defects in Oculo-Facio-Cardio-Dental (OFCD) s

102 We correlate fgf8 deficient laterality defects in the brain and viscera with the abs

103 Consistent with the laterality defects observed in these individuals, we fou

104 by dysfunction of BCOR may result in cardiac/laterality defects of OFCD syndrome.

105 Forty-one percent of these patients also had laterality defects of the abdominal organs.

106 ts in cardiovascular malformations and other laterality defects of visceral organs.

107 ects and partially penetrant cardiopulmonary laterality defects resulting from an abnormal Nodal->Pit

108 Laterality defects such as situs inversus are not uncomm

109 The spectrum of laterality defects was closely correlated with randomize

110 Cardiac laterality defects were partially rescued by human NPHP4

111 ric kidney cysts, body axis curvature, organ laterality defects, and hydrocephalus-defects that could

112 der characterized by sino-pulmonary disease, laterality defects, and male infertility.

113 found that Pierce1-null mice exhibit severe laterality defects, including situs inversus totalis and

114 causes concordant heart, brain and visceral laterality defects, indicating that loss of KV cilia mot

115 cterized by airway disease, infertility, and laterality defects, often caused by dual loss of the inn

116 iants cause ciliary dysmotility and PCD with laterality defects.

117 as defined by multiple malformations without laterality defects.

118 nd that loss of cftr function leads to organ laterality defects.

119 146 unrelated patients with similar cardiac laterality defects.

120 severe C-E defects exhibited an increase in laterality defects.

121 l pathway activity, resulting in epithalamic laterality defects.

122 Smo and Shh/Ihh compound mutants, also have laterality defects.

123 ion of exons 2 and 3 in Ttc25 presented with laterality defects.

124 This work shows synaptic laterality depending on sex and estrous cycle phase in m

125 We characterize a novel laterality determinant in Xenopus laevis: the ATP-sensit

126 la govern respiratory mucociliary clearance, laterality determination and the transport of gametes an

127 s is seen in up to 28% of PCD cases, in whom laterality determination specified by CP-less embryonic

128 , suggesting that BCOR is required in normal laterality determination.

129 cant morbidity and mortality associated with laterality disease almost always are attributed to compl

130 man clinical studies and in animal models of laterality disease suggest that all of these features of

131 und in individuals lacking overt features of laterality disease.

132 re was no significant difference in the age, laterality, disease, or disease status (treatment naive

133 ructure underlies its role in heterotaxy and laterality disorders.

134 airway disease, infertility, and left-right laterality disturbances, usually as a result of loss of

135 ese reductions did not vary with handedness, laterality, duration or severity of symptoms.

136 ymmetries may also contribute to behavioural laterality, e.g. handedness.

137 icant age effect (old<young) in HC group and laterality effect (L>R) in both groups in the FA measure

138 Our preferred interpretation of this laterality effect involves differential strength of conn

139 s, and its origins and relationship to other laterality effectors are largely unknown.

140 Similar laterality effects were not observed for an odor detecti

141 Laterality effects within the PFC were also assessed in

142 l, adjusting for factors such as nodal size, laterality, extranodal extension, margin status, and adj

143 eight of these were for a different contrast/laterality; five for a different gender and/or race/ethn

144 responders vs nonresponders, mean [SD] group laterality for individual lesion seeds, -0.79 [0.18] vs

145 d central pair (CP) agenesis and normal body laterality, from two unrelated families.

146 site direction and for a different contrast, laterality, gender, and/or race/ethnicity.

147 alterations in the expression of downstream laterality genes, but at a lower penetrance.

148 or genes through which FGF signaling affects laterality have not been described.

149 Outcome measures included demographics, laterality, history of corneal trauma, prior ocular hist

150 the corpus callosum (AgCC) and found reduced laterality (i.e., greater likelihood of bilaterality or

151 eye hospital to explore whether any sex and laterality imbalances were present in patients who under

152 Our findings broaden our understanding of lateralities in neural function, provide insights into h

153 In contrast, males did not show laterality in any of those parameters.

154 reaking the left-right axis: implications of laterality in development and disease' was held in June

155 Here, we measured symmetry and laterality in early olfactory processing in the rat.

156 exity or overall glial number nor effects of laterality in either measure.

157 est the existence of a substantial degree of laterality in gustatory signaling mechanisms in nematode

158 s about the mechanisms underlying behavioral laterality in humans.

159 findings suggest the possibility of aberrant laterality in neural pathways and connectivity patterns

160 l MR imaging can be used to measure language laterality in patients with medically intractable focal

161 This asymmetry increased with laterality in spatial tuning.

162 speech and block designs, which report more laterality in speech processing and associated semantic

163 sults highlight the importance of evaluating laterality in the MeA and suggest that the left and righ

164 upffer's Vesicle and in the establishment of laterality in the zebrafish embryo.

165 obal-based connectivity was used to test for laterality in these effects.

166 ar matrix remodeling in the establishment of laterality in vertebrates.

167 ation of beta-catenin is sufficient to alter laterality in zebrafish.

168 When these neurons are silenced, exploratory laterality increases, with more extreme leftiness and ri

169 functional MR imaging data by calculating a laterality index (LI) after using independent component

170 ering approach to the commonly used a priori laterality index (LI) threshold (LI < 0.20 as atypical)

171 mental group correlated with changes in fMRI laterality index and with paretic hand electromyography

172 A laterality index to compare the tract size in the two he

173 ith increased activated volume and decreased laterality index versus baseline values.

174 Individual participant laterality indexes showed a strong trend (P=.059) toward

175 Language laterality indexes were calculated for each participant.

176 nt damage to the optic tract had even higher laterality indices due to direct degeneration.

177 ngstanding damage to either V1 or LGN showed laterality indices greater than 0.5 at the highest inten

178 Here we characterize a cascade of laterality information in the zebrafish embryo and show

179 al in buffering the influence of the flow of laterality information on the left-right progression of

180 gh establishing and subsequently reinforcing laterality information over the course of cardiac develo

181 A high degree of laterality is also important for differential sampling b

182 literature on the prognostic value of tumor laterality is conflicting.

183 In the vertebrate embryo, information on laterality is conveyed to the node, and subsequently to

184 The origin of laterality is cytoplasmic, ancient, and highly conserved

185 In zebrafish, laterality is determined by the motility of cilia in Kup

186 Recent studies have proposed that this laterality is due to different underlying control strate

187 Laterality is fundamental to the vertebrate body plan.

188 In vertebrates, laterality is initiated at the embryonic left-right orga

189 ization of how fluid flow dynamics modulates laterality is lacking.

190 ral function, provide insights into how this laterality is molecularly encoded, and reveal an unusual

191 ing the breasts; however, the basis for this laterality is unknown.

192 Functional left/right asymmetry ("laterality") is a fundamental feature of many nervous sy

193 either pain judgment (painful/nonpainful) or laterality judgment (left/right) of the body parts.

194 aphic OA variables included knee OA, knee OA laterality, knee OA severity, concomitant knee and hip O

195 A screen for mutations that affect habenular laterality led to the identification of the sec61a-like

196 pping axes: eccentricity (centre-periphery), laterality (left-right), and elevation (upper-lower) thr

197 1 US women with early breast cancer of known laterality (left-sided or right-sided) who were register

198 nction mutations in CCDC114 causing PCD with laterality malformations involving complex heart defects

199 ia phenotypes that include hydrocephalus and laterality malformations.

200 mbryos often exhibited altered expression of laterality markers, enlarged brain ventricles, kidney cy

201 We propose that intrinsic molecular laterality may have a role in L-R asymmetric breast tumo

202 ool to investigate tissue-specific molecular laterality mechanisms.

203 ean of the distribution biased the perceived laterality of a subsequent stimulus, whereas the distrib

204 The corresponding tDCS-induced changes in laterality of activations were related to the microstruc

205 aimed to determine the relationship between laterality of acute intracerebral haemorrhage (ICH) and

206 Hemispheric laterality of amyloid burden was compared between Abeta(

207 nd lung exposures were greater than now, the laterality of an irradiated breast cancer could measurab

208 first rotation is directly influenced by the laterality of asymmetric gene expression.

209 The size, number, and laterality of calcifications and the morphologic charact

210 of this second rotation is determined by the laterality of cardiac jogging and is not directly influe

211 Thus, handedness influences the laterality of clinical and radiological joint involvemen

212 ing rehabilitation interventions specific to laterality of damage.

213 for the gender and age of presentation, the laterality of dermolipoma, and features of OAVS.

214 eristics associated with the age of patient, laterality of disease, and extent and location of tumor-

215 Patient and disease characteristics (age, laterality of disease, treatment status) were compared a

216 The location, retinal layer, and laterality of FH were recorded by 1 pediatric vitreoreti

217 Here, we analyzed the temporal dynamics and laterality of gene expression in human and macaque monke

218 ative MR imaging can depict the presence and laterality of HA in TLE with accuracy rates that may exc

219 = 2666), we observe a trend towards reduced laterality of hand skill for the minor allele (P = 0.002

220 field of an FEF neuron was predicted by the laterality of its SC inputs.

221 the parietal lobe but there was no effect of laterality of lesion or correlation between lateral fron

222 While laterality of lesion was not a factor, we did find some

223 indications for wear, symptoms, location and laterality of limbal stem cell deficiency, coexisting oc

224 They were blinded to the laterality of microneedle and sham roller assignments.

225 Our observations imply that the laterality of motor handedness preference in C. elegans

226 ntradiction to this model, both symmetry and laterality of nasal air flow have been reported to be in

227 Nodal signaling subsequently determines the laterality of neuroanatomical asymmetries.

228 even after adjusting for age, sex, obesity, laterality of pain, and depression.

229 eural malignancy and the presence, size, and laterality of pleural effusions.

230 We examined the laterality of positive lymph nodes based on tumor locati

231 n, focal laser, panretinal photocoagulation, laterality of procedure, ranibizumab, bevacizumab, fundu

232 ation, inherited or de novo, was inferred by laterality of Rb and positive family history of Rb.

233 teral hemisphere, but known mediators of the laterality of RGC axons are not repatterned in the absen

234 esentation, participants verbally judged the laterality of rotated images of feet, hands, and whole-b

235 The results of these tests were analyzed by laterality of RT and compared with baseline cardiovascul

236 We also explored the laterality of subcortical regions to identify characteri

237 leral flap, laser suture lysis, surgeon, and laterality of surgery.

238 The timing and laterality of symptom onset relates to focal asymmetric

239 artery (BAA) system, resulting in randomized laterality of the aortic arch.

240 njection sites also result in differences in laterality of the connections.

241 The spatial extent, region, and laterality of the cortical regions most responsive to va

242 The results demonstrate that laterality of the dorsal forebrain influences the format

243 yos' bodyplans exhibit consistently oriented laterality of the heart, viscera, and brain.

244 The laterality of the ICH does not appear to affect the leve

245 Laterality of the internal organs of vertebrates is dete

246 involving Nodal signaling that patterns the laterality of the lateral mesoderm in vertebrates has be

247 triking structure-function relationship: the laterality of the response field of an FEF neuron was pr

248 nance of neglect follow from the anatomy and laterality of the ventral regions that interact with the

249 h with their characteristic TGCT incidences, laterality of tumors and incidence of testicular abnorma

250 is evident from a study that showed that the laterality of unilateral temporolimbic discharges is ass

251 /absence of a systemic inflammatory disease, laterality of uveitis, and smoking status were not assoc

252 rotaxia syndrome, characterized by anomalous laterality of visceral organs and complex congenital hea

253 orm a time-out (n=12), missing indication of laterality on the patient's consent form (n=10), absence

254 ar pedicle caliber or length with regards to laterality or gender.

255 subjects), and far less commonly in isolated laterality or HPE patients (approximately 1% for each).

256 minal carboxylate moiety and is required for laterality organ development in zebrafish.

257 do not contribute to kindlin-2 binding or to laterality organ development.

258 d malformation of the Kupffer's vesicle (KV) laterality organ.

259 ormation in Kupffer's Vesicle, the zebrafish laterality organ.

260 FGF signaling and involves ciliogenesis in a laterality organ.

261 ts affected with vitiligo (P</=.009) but not laterality (P=.06) or duration of disease (P>/=.54).

262 d beta1b knockdown largely recapitulated the laterality phenotype of alphaV morphants.

263 In AgCC individuals, language laterality positively correlated with verbal IQ.

264 tor laterality and uncorrelated motor-visual laterality, possibly because bill-held tools are viewed

265 Regardless of tinnitus laterality, post hoc testing indicated reductions that w

266 ward shift in Edinburgh Handedness Inventory laterality quotient scores as compared with both their u

267 incidence patterns by sex, age at diagnosis, laterality, race/ethnicity, and year of diagnosis.

268 4 patients (3346 males and 2508 females) and laterality recorded for 3780 eyes (1990 treatments in th

269 ricans, Hispanics, Asians, and Indians), eye laterality, refraction, intraocular pressure, axial leng

270 y symmetric structure and how nervous-system laterality relates to the L/R asymmetry of internal orga

271 was reliably invoked regardless of response laterality, response modality, sensory feature, and rewa

272 cortex in the contralateral hemisphere (the 'laterality-shift' hypothesis).

273 f heterotaxy, indicating a conserved role in laterality specification.

274 hspb12 randomizes heart, brain and visceral laterality, suggesting that these two genes have partial

275 The following data were reviewed: age, sex, laterality, symptom onset, clinical presentation, histop

276 a disorder of left-right body patterning, or laterality, that is associated with major congenital hea

277 For sex and laterality, the 95% CIs did not overlap the 50% mark, in

278 ollected regarding lung nodule number, size, laterality, timing of resolution, and pulmonary surgery.

279 Stroke type, laterality, timing, and outcome were reported.

280 Our results link adult neuronal laterality to the generation of the A/P axis at the two-

281 (age, sex); ocular disease characteristics (laterality, type of scleritis, degree of scleral inflamm

282 cancer from 1986 to 1993, had known disease laterality, underwent breast surgery, and received adjuv

283 nt predictors of conversion, whereas sex and laterality (unilateral vs bilateral) had no influence.

284 Photopsia assessment included (1) laterality (unilateral, bilateral but not simultaneous,

285 e tissues coordinate liver bud formation and laterality via cell repulsion.

286 es included epidemiologic data: age, gender, laterality, visual acuity, duration of symptoms, and und

287 Language laterality was increasingly right-sided in patients who

288 f early-stage resected colon cancer, disease laterality was not associated with long-term OS or CSS.

289 was coded both times) and presumed (the eye laterality was not coded) macular hole reoperations with

290 Among those who did not, tumour laterality was of little relevance to subsequent mortali

291 Laterality was positively correlated with behavioral mea

292 Laterality was randomized in the brain, heart and viscer

293 ac mortality ratio (left versus right tumour laterality) was 1.20 (95% CI 1.04-1.38) less than 10 yea

294 result in randomization of visceral organs' laterality, we hypothesized that LRD may also function i

295 a screen for mutations that disrupted brain laterality, we identified a nonsense mutation in the T-b

296 The age, sex, and laterality were recorded in both groups.

297 e of AVHs and neuropsychological measures of laterality were studied as predictors of site-specific r

298 We examined the association of language laterality with a range of potential clinical predictors

299 deductive analyses to correlate malformation laterality with asymmetries in thoracic anatomy, critica

300 as unclear, however, if findings of atypical laterality would be observed in a larger sample, and at