ライフサイエンスコーパス: laurdan

1 fectants was measured by labeling cells with Laurdan.

2 roscopy with an environment-sensitive probe, laurdan.

3 ne physical state detected by bis-pyrene and laurdan.

4 that membrane raft accumulation assessed by Laurdan (6-dodecanoyl-2-dimethyl aminonaphthalene) label

5 As a fluorescent probe we used LAURDAN (6-dodecanoyl-2-dimethylaminonaphthalene), a dye

6 The effects of temperature and pH on Laurdan (6-lauroyl-2-(dimethylamino)naphthalene) fluores

7 6-Dodecanoyl-2-dimethylamino-naphthalene (LAURDAN), 6-propionyl-2-dimethylamino-naphthalene (PRODA

8 the emission intensity at two wavelengths of Laurdan, a membrane fluorescent dye sensitive to local m

9 erived from the exogenous fluorescent probes laurdan, acridine orange, propidium iodide, and Snarf ar

10 ence emission spectra of Prodan, Patman, and Laurdan all showed spectral changes consistent with an i

11 ce polarization of the phase-sensitive probe Laurdan and FRET between phase-partitioning probes in mo

12 ctroscopic data, generalized polarization of Laurdan and infrared carbonyl and phosphate stretching f

13 axation in response to the excited states of Laurdan and Prodan.

14 opy using the membrane probes bis-pyrene and laurdan) and compared with sPLA(2) activity.

15 of 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan) and Lissamine rhodamine B 1,2-dihexadecanoyl-sn

16 scanning microscopy using the membrane probe laurdan argued that susceptibility to sPLA(2) is a conse

17 onstrate this analysis in NIH3T3 cells using Laurdan as a biosensor to monitor changes in the membran

18 embrane interactions were investigated using Laurdan as a membrane-anchored fluorescent dye.

19 Using Prodan and Laurdan as fluorescent membrane probes, phosphatidylchol

20 we investigate the fluorescence lifetime of Laurdan at two different emission wavelengths and find t

21 -sensitive probes Laurdan, carboxyl-modified Laurdan (C-Laurdan), Di-4-ANEPPDHQ, and Di-4-AN(F)EPPTEA

22 ubbles with environmentally-sensitive probes Laurdan, carboxyl-modified Laurdan (C-Laurdan), Di-4-ANE

23 P values lead us to further propose that the Laurdan chromophore resides in the polar headgroup regio

24 eriments utilizing the phase-sensitive probe Laurdan confirmed gel-phase characteristics at pH 2, exp

25 The Laurdan-derived LogD values at pH 7.4 were found to be 2

26 Second, laurdan detected increased solvation of the lower headgr

27 probes Laurdan, carboxyl-modified Laurdan (C-Laurdan), Di-4-ANEPPDHQ, and Di-4-AN(F)EPPTEA (FE), for

28 ical scheme based on the use of a lipophilic Laurdan dye for examining MIN6 cell membranes upon expos

29 Analysis of the spatial distribution of laurdan fluorescence at several temperatures indicated t

30 Interestingly, the two-photon Laurdan fluorescence images showed snowflake-like lipid

31 ted with light polarized in the y direction, Laurdan fluorescence in the center cross section of the

32 The generalized polarization (GP) of Laurdan fluorescence in the center cross section of the

33 ative evaluation of the phase behavior using Laurdan generalized polarization, and of enzyme binding

34 ere used to assess merocyanine 540 emission, laurdan generalized polarization, phosphatidylserine exp

35 Binding experiments and Laurdan generalized-polarization measurements suggest th

36 xistence temperature regime and based on the Laurdan GP data, we observe that when the hydrophobic mi

37 As judged by the LAURDAN GP histogram, we concluded that the lipid phase

38 Detection of the fluorescent properties of Laurdan has been proven to be an efficient tool to inves

39 Among the dyes used in membrane studies, LAURDAN has the advantage to be sensitive to the lipid c

40 isruption of lipid order was consistent with Laurdan imaging results indicating that POVPC and PGPC d

41 ution of polarity and dipolar relaxations of LAURDAN in each pixel of an image.

42 his result indicates that the chromophore of Laurdan in PLFE GUVs is aligned parallel to the membrane

43 From the LAURDAN intensity images the excitation generalized pola

44 From the Laurdan intensity images the generalized polarization fu

45 The generalized polarization (GP) of Laurdan-labeled cells contains useful information about

46 ated and unconjugated BSs as determined with Laurdan-labeled liposomes.

47 Optical microspectrophotometry of Laurdan-labeled neutrophils revealed a large blue shift

48 arse-grained molecular dynamics simulations, Laurdan multiphoton imaging, and atomic force microscopy

49 ous fluorescence study using dipyrenylPC and Laurdan probes and thus support the proposition that 1)

50 Various fluorescent probes (Prodan, Laurdan, pyrene-labeled fatty acid, and dansyl-labeled p

51 emission of the environment-sensitive probe, laurdan, revealed that erythrocyte membrane order decrea

52 Traditionally the spectral shift of Laurdan's emission from blue in the ordered lipid phase

53 and find that when the dipolar relaxation of Laurdan's emission is spectrally isolated, analysis of t

54 phasor representation to analyze changes in Laurdan's fluorescence lifetime we obtain two different

55 A reduction of Laurdan's generalized polarization in relation to change

56 of approximately 3.9), no differences in the Laurdan spectra of the respective BS were found at pH 6.

57 The LAURDAN spectrum is sensitive to the lipid composition a

58 We use the lipophilic fluorescence probe Laurdan to study cell membranes.

59 The emission spectrum of LAURDAN was examined by two-photon fluorescence microsco

60 natural lipid mixtures, in which the probe, LAURDAN, was incorporated.

61 of 6-dodecanoyl-2-dimethylamine-naphthalene (LAURDAN), which is sensitive to the changes in water con

62 e use of the fluorescent fatty acid analogue Laurdan, whose emission spectrum is sensitive to structu

63 e order (assessed with the fluorescent probe laurdan) with hydrolysis rate revealed that sPLA(2) acti