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1 The unlabeled drug dose and plasma concentration leading to a 50% reduction of (11)C-BMT-136088 specific bindi
2 signalling is implicated may be caused by aberrant salience leading to a change in the nature of the information that is
3 of a cytosine for a thymine nucleotide (C64T) at codon 22, leading to a premature stop codon (R22X) in the albino robust
5 on margin, (2) intraparenchymal spread of neoplastic cells, leading to an anatomically separate but genetically related r
6 rol depleted membranes, PmB forms clusters on the membranes leading to an indentation of the bilayers and increase in wat
7 Absence of IL-4Ralpha limits thymocyte emigration, leading to an intrathymic accumulation of mature thymocytes w
8 (a fixed height, not a fixed fraction of the peak maximum) leading to any number of calibration curves.
9 temperature proceeds with high levels of diastereocontrol, leading to beta-amino ketones in high yields.
10 al domination with vancomycin-resistant Enterococcus (VRE), leading to bloodstream infection in hospitalized patients.
12 esters induced an unstable system after gastric conditions leading to coalesced oil droplets, while Tween80 emulsions re
14 f other noncanonical PRC1 complexes and of PRC2, the latter leading to deposition of histone H3 lysine 27 methylation chr
15 licit central pro-inflammatory cytokine production, in turn leading to depression and cognitive deficits.
16 helial cell contractility and adherens junction disassembly leading to endothelial barrier breakdown.
17 ctive site inhibitor reduces Skp2 levels and stabilizes LT, leading to enhanced MCV replication and transmission.
18 r, the connections between the apoptotic cascade and events leading to extrusion are not fully understood.
20 el fusion involving USP9X-ERAS formed by chromothripsis and leading to high expression of ERAS, a constitutively active R
22 on of inflammatory monocyte-derived cells (MCs) in the CNS, leading to improved clinical outcome.
23 RR2HAGES improved their predictive value for major bleeding leading to improved clinical usefulness compared to the origi
24 mineralization and enhanced osteoclast-progenitor survival, leading to increased osteoclastogenesis.
25 nal morphologies in a selected manner throughout the brain, leading to intellectual deficits and sensory dysfunction in t
26 cocorticoid biosynthesis in the epidermis of psoriatic skin leading to localized deficiency of cortisol.
28 brate ribonuclease, is known to promote cell proliferation, leading to neovascularization as well as neuroprotection in m
30 unctional hyperdopaminergia and neurodegenerative phenotype leading to premature death in 36% of the population.
31 escents in the United States suffer from dental infections, leading to pulp necrosis, arrested tooth-root development and
33 brosis is caused by mutations in the CFTR chloride channel, leading to reduced airway surface liquid secretion.
34 shown to be interference with the lipid signaling pathway, leading to reduced expression of MDR transporters and thereby
35 ch the redox group between the oxidized and reduced states, leading to reversible switching of the DNA conductance betwee
36 These FYCO1 variants may impair autophagic function, leading to RV formation in sIBM patient muscle.
37 d piwi-interacting RNA intermediates with 3' end extension, leading to severe reduction of mature piwi-interacting RNAs i
38 t currents and rightward shifts in inactivation parameters, leading to significant increases in the magnitude of window c
39 ome households may experience greater HPA and HPG activity, leading to steeper decreases in cortical thickness with age.
40 erapies do not experience uniform uptake throughout tumors, leading to sub-lethal cell killing that can impart treatment
41 th DHA and Physcion activates AMP-activated protein kinase, leading to synergistic inhibition of human leukemia cell viab
42 mPTP opening decreases the mitochondrial membrane potential leading to the activation of Ca(2+)-independent phospholipase
43 epared and studied by variable temperature NMR spectroscopy leading to the conclusion that the rate-determining step in t
44 We report the discovery of self-assembly strategies leading to the emergence of lipid bicontinuous single crystal
45 We observe extensive splicing diversity leading to the formation of altered open reading frames (ORFs
46 s immune response to FVIII, because of a lack of tolerance, leading to the formation of inhibitory antibodies.
47 owever, the identity and hierarchy of the HDR (sub)pathways leading to the formation of PGE products remain elusive.
48 tions, i.e., the light activation of o-methylbenzaldehydes, leading to the formation of reactive o-quinodimethanes (photo
49 RNA splicing of P-transposable element transcripts in vivo, leading to the production of the non-transposase-encoding mat
50 icularly weak, the network operates close to an instability leading to unbounded cortical activation.
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