ライフサイエンスコーパス: leaflet

1 otion reduction (i.e., involving >50% of the leaflet).

2 ention (leaflet) or 'usual care' control (no leaflet).

3 e) and Cardamine hirsuta (complex shape with leaflets).

4 lter the surface electrostatics of the outer leaflet.

5 xtracted lipids were from the membrane outer leaflet.

6 ependent manner at the inner plasma membrane leaflet.

7 omprise the hydrophobic portion of the outer leaflet.

8 olipid lipopolysaccharide (LPS) in the outer leaflet.

9 leaflet and phospholipids (PLs) in the inner leaflet.

10 ntral strip" border with the intergeniculate leaflet.

11 ing can escape by lipid efflux via the lower leaflet.

12 capturing FGF2 at the outer plasma membrane leaflet.

13 metry of 0.63 +/- 0.04 in favor of the outer leaflet.

14 to which it is bound as well as the opposing leaflet.

15 h its C-terminus extending into the opposite leaflet.

16 refill of phospholipids to the ER cytosolic leaflet.

17 ner leaflet but not of the IMPs of the outer leaflet.

18 brane surface and insertion into the lipid A leaflet.

19 longitudinal diffusion of IMPs of the outer leaflet.

20 leaflet and lipopolysaccharides in the outer leaflet.

21 livery of exogenous lipids to the cell outer leaflet.

22 the inner leaflet exceeds that at the outer leaflet.

23 o a ring-shaped complex on the outer-bilayer leaflet.

24 that is specific to the extracellular lipid leaflet.

25 The key manipulation was the accompanying leaflet.

26 erol contents, respectively, at the inner PM leaflet.

27 biomechanical strength to the cardiac valve leaflets.

28 ymmetry between the inner and outer membrane leaflets.

29 a surface charge difference between bilayer leaflets.

30 that transfer phospholipids between membrane leaflets.

31 g transition temperatures of the two bilayer leaflets.

32 mation of K(A) values for individual bilayer leaflets.

33 f lipids between the inner and outer bilayer leaflets.

34 veloped leaves with smooth margins and fused leaflets.

35 kening and calcification of the aortic valve leaflets.

36 that was associated with loss of EC from VV leaflets.

37 nt pathway to regulate the growth of lateral leaflets.

38 unnel connecting NTD to the luminal membrane leaflet 50 angstrom away.

39 XITY inhibits growth locally around emerging leaflets, accentuating shape differences created by patt

40 lated mitral annular dilation and inadequate leaflet adaptation are considered mechanistic culprits.

41 nge techniques) versus passive intervention (leaflet advice alone).

42 nge techniques) versus passive intervention (leaflet advice alone).

43 MtREV1 led to adaxialized leaves and ectopic leaflets along the dorsoventral axis.

44 l 2018, the area between the anterior mitral leaflet and aortic valve was inspected at myectomy in 10

45 cies flip from the top leaflet to the bottom leaflet and become trapped.

46 2)-mediated recruitment of FGF2 at the inner leaflet and heparan sulfates capturing FGF2 at the outer

47 The first arises from the inner leaflet and is coordinated by hydrophobic residues of th

48 ic bilayer having phospholipids in the inner leaflet and lipopolysaccharides in the outer leaflet.

49 opolysaccharides (LPS) residing in the outer leaflet and phospholipids (PLs) in the inner leaflet.

50 er structure with phospholipids in the inner leaflet and the complex glycolipid lipopolysaccharide (L

51 Outer-leaflet and total fractions of PG were determined via ze

52 nd the physiological microenvironments of PV leaflet and valve cells for correctively engineering age

53 itutive laws for dynamic behaviour of mitral leaflets and chordae under physiological conditions.

54 is redistributed within both plasma membrane leaflets and intracellular membranes.

55 cing to investigate the global changes of PV leaflets and passage zero PV interstitial cells in their

56 structurally abnormal elongated mitral valve leaflets and remodeled intramural coronary arterioles, w

57 -) mice results in rapid regression of valve leaflets and severe valve dysfunction.

58 ) mice results in rapid regression of valve leaflets and severe valve dysfunction.

59 In detail, IFC valve leaflets and supernatants of the washing solutions were

60 the dye partition coefficients of individual leaflets and the generalized polarization of the fluores

61 three different constitutive laws for mitral leaflets and two laws for chordae tendineae are selected

62 initiation and later in the basal regions of leaflets, and finally in vein tissues at late leaf devel

63 rs, and certified facilitators; standardised leaflets; and standardised advance directives.

64 scatheter mitral valve repair (TMVr) through leaflet approximation had reduced rates of HF hospitaliz

65 demonstrate that PIP(2) molecules in the top leaflet are fully mobile, while the PIP(2) molecules in

66 ile, while the PIP(2) molecules in the lower leaflet are immobilized on the oxide support.

67 flat bilayers, whose specific areas in each leaflet are matched to those of corresponding tensionles

68 uced valve calcification, lower aortic valve leaflet area, increased M2 macrophage polarization, and

69 e compact E. coli MscL at the membrane inner-leaflet, as a consequence of a rotated TM2 helix.

70 eously within the cells, between the bilayer leaflets, as well as between lateral domains within the

71 Control group participants received the leaflet at study completion.

72 Single leaflet attachment occurred in five (7%) of 72 patients.

73 simplified strategy to lacerate the anterior leaflet before transcatheter mitral valve replacement.

74 Owing to its outer leaflet binding, Pro12A is much more sensitive to choles

75 diffusion of TMPs and the IMPs of the inner leaflet but not of the IMPs of the outer leaflet.

76 movement of small molecules across membrane leaflets but also is sensitive to higher-level ordering

77 pholipids can be carried by Lp(a) into valve leaflets but can also be formed in situ from cell membra

78 pid anchor and reoriented to the periplasmic leaflet by the channel-forming WzmWzt ABC transporter fo

79 of TMPs and IMPs of both the inner and outer leaflets by changing the density of TMPs.

80 alysis identified calcified raphe and excess leaflet calcification (defined as more than median calci

81 Calcified raphe and excess leaflet calcification were associated with increased ris

82 Both calcified raphe plus excess leaflet calcification were found in 269 patients (26.0%)

83 of raphe, calcification grade in raphe, and leaflet calcium volume were assessed with CT analysis in

84 ordered domains in a SM and cholesterol-rich leaflet can be suppressed by an opposite leaflet contain

85 d eye health and retinal screening promotion leaflet can increase knowledge of diabetic retinopathy,

86 ther lipid transfer between membrane bilayer leaflets can lead to displacement of charge across the m

87 Mitral regurgitation occurs from leaflet coaptation failure that is either primary (a pro

88 n in the corresponding region of an opposite leaflet composed of unsaturated phosphatidylcholine (PC)

89 We first fit these three mitral leaflet constitutive laws and two chordae tendineae laws

90 ain and stress are insignificant because all leaflet constitutive laws are fitted to the same set of

91 ich leaflet can be suppressed by an opposite leaflet containing unsaturated PC and cholesterol.

92 have defined distributions of lipids in each leaflet, controlled by lipid scramblases and flip/floppa

93 The second lipid arises from the outer leaflet coordinate between two E protein helices.

94 erse diffusion of TMPs and IMPs of the inner leaflet, depending on the strength of the association be

95 mena, including blood damage and accelerated leaflet deterioration, this study demonstrates the poten

96 in which the physical characteristics of one leaflet differ from those of the other.

97 important roles in the outgrowth of lateral leaflets during compound leaf development of M. truncatu

98 ternational experience with DMR due to flail leaflets echocardiographically diagnosed.

99 s that are directed only at the mitral valve leaflets (eg, transcatheter mitral valve repair).

100 a promigratory to an elastic ECM drive valve leaflet elongation.

101 growth relative to edge-patterning, enabling leaflet emergence, while REDUCED COMPLEXITY inhibits gro

102 ned in close proximity to the inner membrane leaflet, enabling the reduction of membrane-inserted myc

103 e, followed by membrane curvature and distal leaflet engagement.

104 Here we demonstrate that the cytosolic leaflet ER morphogenic protein reticulon (RTN) protects

105 mmetry, the net-negative charge at the inner leaflet exceeds that at the outer leaflet.

106 P7 valve leaflets exhibit two distinct collagen- and glycosaminog

107 orescence microscopy, which revealed a local leaflet expansion upon exposure to elevated concentratio

108 study identified and quantified significant leaflet flutter induced by the use of thinner tissues th

109 the diffusion of TMPs and IMPs of the inner leaflet from normal to confined-hop diffusion.

110 In this study, we isolated PV leaflets from porcine hearts in different age groups (~

111 Aortic valve leaflet fusion pattern and sex were not associated with

112 lve dysfunction but was independent from BAV leaflet fusion type.

113 circadian pacemaker-and the intergeniculate leaflet (IGL) through intrinsically photosensitive retin

114 x (TM) and another that penetrates the inner leaflet (IM).

115 tains negatively charged lipids in the inner leaflet in an injured cell.

116 mferential directions and the collagen of PV leaflets increased from young to adult age, while the ul

117 ) and cholesterol-rich ordered domain in one leaflet induces ordered domain formation in the correspo

118 8, known to be located on the outer membrane leaflet, interacts with the transmembrane protein integr

119 alysis of the lipid composition of the outer leaflet is important for understanding cell membrane bio

120 he exclusion of phospholipids from the outer leaflet, is key to creating an almost impenetrable barri

121 if cholesterol solvates equally well in both leaflets, it will redistribute to cancel both leaflet te

122 nscaval access, Potts and Glenn shunts), and leaflet laceration (BASILICA, LAMPOON, ELASTA-Clip, and

123 For leaflet laceration, the "Flying V" configuration concent

124 ntentional laceration of the anterior mitral leaflet (LAMPOON) is an effective adjunct to transcathet

125 To model its outer leaflet, Langmuir monolayers and cushioned supported bil

126 , we found that C8-PI(3,5)P(2) blocked outer leaflet lipid mixing.

127 lipid asymmetry by partial exchange of outer-leaflet lipid, 4) verification of lipid asymmetry and st

128 sts of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS).

129 omotes the lipid exchange of the fused outer leaflets mediated by lipid diffusion.

130 The two calorimetric peaks of the individual leaflets merged into a single peak over time, suggestive

131 a loosely and tightly docked state preceding leaflet merger using arresting point mutations in SNARE

132 Further THV design improvements and leaflet modification strategies are needed to mitigate t

133 ogeneity during postnatal ECM remodeling and leaflet morphogenesis.

134 nuated leaflet thickening (HALT) and reduced leaflet motion (RLM).

135 nuated leaflet thickening (HALT) and reduced leaflet motion observed on 4-dimensional computed tomogr

136 Subclinical leaflet thickening and reduced leaflet motion of bioprosthetic aortic valves have been

137 let-based strategy in preventing subclinical leaflet-motion abnormalities.

138 tic documents, including patient information leaflets, need to state consistently the nature and limi

139 Leaflet numbers in the mutant were increased along the p

140 icago truncatula, a mutant line with altered leaflet numbers was isolated and characterized.

141 nd to redistribute lipids added to the outer leaflet of ATG9 vesicles, thereby enabling growth into a

142 ingomyelin, an abundant lipid of the luminal leaflet of BCV membranes, and normally absent from the c

143 ) or lipooligosaccharides (LOS) and an inner leaflet of glycerophospholipids (GPL).

144 Model LDs emerge on the membrane leaflet of higher coverage, which is improved by the ins

145 probe, Pro12A, stains exclusively the outer leaflet of lipid bilayers of liposomes, as evidenced by

146 The OM is asymmetric and contains an outer leaflet of lipopolysaccharides (LPS) or lipooligosacchar

147 tly demonstrated FGF2 oligomers at the inner leaflet of living cells with a FGF2 dimer being the most

148 ins accumulating at the membrane cytoplasmic leaflet of living DCs, in dynamic coordination with nasc

149 e cell-type-specific components of the outer leaflet of mammalian plasma membranes.

150 sphingolipids that are abundant in the outer leaflet of plant plasma membranes.

151 characterize the phospholipids in the outer leaflet of red blood cells (RBCs) is reported.

152 phagocyte recognition marker, from the outer leaflet of senescent RBCs.

153 oPC is transported across the inner membrane leaflet of the BBB via the major facilitator superfamily

154 equence of a breakdown in the outer membrane leaflet of the BBB, putting them at increased risk for A

155 is gradually translocated into the cytosolic leaflet of the BCV, invariably followed by cytosolic exp

156 unorubicin is stably inserted into the outer leaflet of the bilayer, verapamil dynamically flip flops

157 laterally associate and embed into the upper leaflet of the bilayer.

158 higher probability of transport to the other leaflet of the bilayer.

159 DHA is transported across the outer membrane leaflet of the blood-brain barrier (BBB) via passive dif

160 r PG biogenesis, is synthesized in the inner leaflet of the cytoplasmic membrane and then translocate

161 ivIVA/GpsB proteins associate with the inner leaflet of the cytosolic membrane and act as scaffolds f

162 , phospholipid synthesis "refills" the outer leaflet of the endoplasmic reticulum (ER) membrane to ma

163 lipid A-binding motif along the periplasmic leaflet of the inner membrane.

164 tentially sense lateral tension on the inner leaflet of the lipid bilayer caused by changes in turgor

165 lateral gate, which is open toward the inner leaflet of the membrane but closes upon drug binding.

166 proteins, phospholipids can migrate from one leaflet of the membrane to the other.

167 rophilic groove of YidC located in the inner leaflet of the membrane until it is translocated to the

168 P2 lipids were being desorbed from the outer leaflet of the membrane.

169 ocalized glycerophospholipids from the outer leaflet of the OM and return them to the inner membrane

170 The inner leaflet of the outer membrane contains phospholipids, wh

171 The negative surface charge of the outer leaflet of the outer membrane of Gram-negative bacteria

172 ore lipopolysaccharides in the extracellular leaflet of the outer membrane.

173 enzyme with the former anchored to the inner leaflet of the outer membrane.

174 G proteins largely function at the inner leaflet of the plasma membrane (PM) using covalently att

175 induced translocation of ASMase to the outer leaflet of the plasma membrane and reduced SM levels in

176 Our data indicate that the inner leaflet of the plasma membrane is most negative, with a

177 showed that sphingomyelin (SM) in the outer leaflet of the plasma membrane is responsible for mainta

178 ne (PE) are usually sequestered to the inner leaflet of the plasma membrane of the healthy eukaryotic

179 l Gag polyproteins are targeted to the inner leaflet of the plasma membrane through their N-terminal

180 is a glycosphingolipid residing on the outer leaflet of the plasma membrane, and acetylcholine recept

181 ining lipids typically enriched in the inner leaflet of the plasma membrane, such as phosphatidylinos

182 explain the behavior of PIP(2) on the inner leaflet of the plasma membrane, where it is involved in

183 important class of lipids found in the outer leaflet of the plasma membrane.

184 charged phosphatidylserine (PS) on the outer leaflet of the plasma membrane.

185 h forms a dense protein lattice on the inner leaflet of the plasma membrane.

186 lls, PS is actively sequestered to the inner leaflet of the PM, but PS redistributes to the outer lea

187 o anchor a synthetic transducer in the outer leaflet of the vesicles, and when the protein was displa

188 d lipids in the aGUVs are found in the outer leaflet of these asymmetric vesicles.

189 catalyze the movement of lipids between both leaflets of a bilayer.

190 formation and then acts to engage the distal leaflets of each membrane and promote stalk widening, cu

191 monocyte accumulation at the aortic side of leaflets of explanted aortic valves.

192 ips between object features (e.g., the three leaflets of poison ivy leaves) and outcomes (e.g., rash)

193 as a general enrichment within the cytosolic leaflets of the Golgi complex, peroxisomes, and outer mi

194 dae tendineae that are attached to specified leaflets of the mitral valve and, subsequently, MC impla

195 eral domains and between the inner and outer leaflets of the plasma membrane.

196 g technique was designed to uncouple the two leaflets of the SLB.

197 cent dyes to monitor the inner and the outer leaflets of the unsupported aGUVs.

198 In the anterior leaflets of those animals, we investigated maladaptation

199 lar barrier formed by the lipopolysaccharide leaflet on the cell surface.

200 brief health behaviour change intervention (leaflet) on self-reported screening uptake, and previous

201 -glycero-3-phospho-rac-glycerol in the outer leaflet only was quantified by zeta-potential measuremen

202 lesterol analogue was localized to the outer leaflet only, the fast diffusion of cholesterol disappea

203 Exclusion criteria included anterior leaflet or commissural prolapse, as well as a mixed caus

204 tments that are directed to the mitral valve leaflets or their supporting structures (eg, cardiac res

205 /No) and randomly allocated to intervention (leaflet) or 'usual care' control (no leaflet).

206 PD discharge bundle including PR information leaflet) or usual care plus the codesigned education vid

207 e that is either primary (a problem with the leaflets) or secondary (chamber dilatation in the settin

208 mplex, including helix 8 burial in the inner leaflet, ordered lysine and arginine side chains in the

209 if its partitioning free energy prefers one leaflet over the other, the resulting distribution bias

210 n bioprosthesis dysfunction, 14 had abnormal leaflet pathology on CT, and 24 demonstrated (18)F-fluor

211 5% CI: 57%, 70%) (151 of 237) (P < .001) and leaflet perforation detection, 81% (95% CI: 71%, 88%) (7

212 ed as abscess or pseudoaneurysm, vegetation, leaflet perforation, and paravalvular leakage), and (c)

213 s superior results for vegetation detection, leaflet perforation, and paravalvular leakage.Supplement

214 mmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysacchari

215 The supra-annular leaflet position and tall stent frame of the self-expand

216 l dynamically flip flops between the bilayer leaflets, possibly rendering its net transport futile.

217 16%, and 1.9+/-2.6% for those who underwent leaflet preservation (n=50).

218 leaflet resection and 8.3+/-3.3 mm Hg after leaflet preservation (P=0.43).

219 leaflet resection versus 481+/-95 m for the leaflet preservation group (P=0.27).

220 in the leaflet resection group and 2 in the leaflet preservation group.

221 al prolapse with either leaflet resection or leaflet preservation was associated with similar transmi

222 mitral gradients after leaflet resection and leaflet preservation, respectively.

223 ecies with compound leaves, the positions of leaflet primordium initiation are associated with local

224 ears; 70.4% men) had MV repair for MR due to leaflet prolapse and were followed prospectively for a m

225 etramer dissociates, binds a single membrane leaflet, recruits AhlB promoting soluble to pore transit

226 ated with phenotype dominated by MAD, marked leaflet redundancy, and repolarization abnormalities.

227 dependently associated with presence of MAD, leaflet redundancy, and T-wave inversion/ST-segment depr

228 ed with male sex, bileaflet prolapse, marked leaflet redundancy, mitral annulus disjunction (MAD), a

229 main formation in the SM+PC-containing outer leaflet relative to ordered domain stability in choleste

230 nd 1.4+/-2.8% for those who were assigned to leaflet resection (n=54), and 66.3+/-10.8 years, 16%, an

231 ot support the hypothesis that a strategy of leaflet resection (versus preservation) is associated wi

232 ring peak exercise was 9.1+/-5.2 mm Hg after leaflet resection and 8.3+/-3.3 mm Hg after leaflet pres

233 +/-1.1 mm Hg; P=0.67) mitral gradients after leaflet resection and leaflet preservation, respectively

234 Equipoise exists between the use of leaflet resection and preservation for surgical repair o

235 urgitation was observed in 3 subjects in the leaflet resection group and 2 in the leaflet preservatio

236 trial, repair of mitral prolapse with either leaflet resection or leaflet preservation was associated

237 regurgitation surgically amenable to either leaflet resection or preservation were randomized at 7 s

238 ng distance was 451+/-147 m for those in the leaflet resection versus 481+/-95 m for the leaflet pres

239 ranscatheter mimic of surgical chord-sparing leaflet resection.

240 rm an ensemble, with the native mitral valve leaflets secured in between, thereby abolishing MR.

241 Nucleobase pairs in the hydrophobic leaflet separate when mechanical force is applied, expos

242 frame, SEV, 18.6%; BEV, 6.9%; P=0.01; valve leaflet, SEV, 23.9%; BEV, 38.5%; P=0.01).

243 e, we observe MBP to insert into its bilayer leaflet side in case of the diseased lipid mixture, wher

244 lipid bilayers of liposomes, as evidenced by leaflet-specific fluorescence quenching with a viologen

245 interstitial cell clusters are apparent with leaflet specificity and differential expression of compl

246 We show that chemometric analysis of peanut leaflet spectra provides accurate identification of diff

247 steps, including docking, merger of proximal leaflets (stalk formation), and formation of a fusion po

248 ated blood flow disturbances and oscillatory leaflet strains.

249 trix (ECM) remodeling during postnatal valve leaflet stratification, but phenotypic and transcription

250 sertion sites at four alleles of the LATERAL LEAFLET SUPPRESSION1 (LLS1) gene, encoding the auxin bio

251 The intervention group's leaflet targeted psychological barriers and provided low

252 /PC inside vesicles, the PC-containing inner leaflet tended to destabilize ordered domain formation i

253 eaflets, it will redistribute to cancel both leaflet tensions almost completely, but if its partition

254 tricle dilates or remodels or as a result of leaflet tethering with impaired coaptation, most commonl

255 so involve opposing lateral stresses in each leaflet that combine to an overall vanishing membrane te

256 logy and surface electrostatics of the outer leaflet, the insertion of ACs, in particular their long-

257 dilatation and tethering of the mitral valve leaflets, there is a linear relationship between LV end-

258 mputed tomographic imaging by hypoattenuated leaflet thickening (HALT) and reduced leaflet motion (RL

259 thrombosis, characterized by hypoattenuated leaflet thickening (HALT) and reduced leaflet motion obs

260 hocardiographic predictors of hypoattenuated leaflet thickening (HALT) in low-risk patients undergoin

261 Subclinical leaflet thickening and reduced leaflet motion of biopros

262 Leaflet thickening was also assessed.

263 development, including mitral valve anterior leaflet thickening, excessive leaflet tip motion, and re

264 adult) and studied the effects of age on PV leaflet thickness, extracellular matrix components, and

265 Subclinical leaflet thrombosis has been reported after bioprosthetic

266 Though rare, leaflet thrombosis is an important adverse outcome, and

267 Subclinical leaflet thrombosis was more frequent in transcatheter co

268 TV dysfunction, endocarditis, and leaflet thrombosis were uncommon after TTVR.

269 Subclinical leaflet thrombosis, characterized by hypoattenuated leaf

270 concerns about ischemic stroke, subclinical leaflet thrombosis, valve thrombosis, and long-term dura

271 lation and potentially attenuate subclinical leaflet thrombosis.

272 esterol show that oxygen and water transit a leaflet through the DOPC and cholesterol rich boundaries

273 It was found that PIP(2) flipped between the leaflets through a defect-mediated process.

274 valve anterior leaflet thickening, excessive leaflet tip motion, and regurgitation jet length >=2 cm,

275 ved in fibromyxomatous changes in the mitral leaflet tissue have not been elucidated.

276 ntentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstru

277 onal laceration of the anterior mitral valve leaflet to prevent LVOT obstruction (LAMPOON) is a trans

278 ime, mobile PIP(2) species flip from the top leaflet to the bottom leaflet and become trapped.

279 embrane lipids from the lumenal or exofacial leaflet to the cytofacial aspect of the bilayer.

280 nduce cholesterol clustering in the membrane leaflet to which it is bound as well as the opposing lea

281 discontinuity displaced the anterior mitral leaflet toward the apex in most young patients, was sign

282 Leaflet traversal and laceration were technically succes

283 The lymphatic system contains intraluminal leaflet valves that function to bias lymph flow back tow

284 perfusion of multiscale vasculature and tri-leaflet valves.

285 At echocardiography, the anterior mitral leaflet was longer in patients with than those without d

286 Thickening of at least one leaflet was observed in 12 of 97 patients (12.4%) in the

287 of the PM, but PS redistributes to the outer leaflet when the cell is damaged or at the onset of apop

288 these phospholipids move to the cell's outer leaflet where they are recognized by so-called PS recept

289 kely cause is a stiffening of the compressed leaflet, which appears to be related to its gel transiti

290 es a site on KCNQ1 within the inner membrane leaflet, which triggers a large conformational change th

291 he hydrophilic headgroup zone of the lipid A leaflet, which was confirmed by the potential of mean fo

292 xtract phospholipids from the membrane outer leaflet, while delivering lipids to the cell to maintain

293 patients with at least one prosthetic valve leaflet with grade 3 or higher motion reduction (i.e., i

294 At least one prosthetic valve leaflet with grade 3 or higher motion reduction was foun

295 The control group received a leaflet with information on smoking cessation.

296 ost abundant phospholipids in the RBCs outer leaflet with PC 34:1 and SM 34:1 being the most abundant

297 ow restricted diffusion of IMPs of the outer leaflet, with our simulations, we conjectured the existe

298 ting for cholesterol sorting in both bilayer leaflets, with a compositional asymmetry of 0.63 +/- 0.0

299 the diffusion of TMPs and IMPs of the inner leaflet within the membrane skeleton corrals.

300 redicted that the position of the pinned THV leaflets would hinder future coronary access in up to 78