ライフサイエンスコーパス: learning and memory

1 ion thought to provide the cellular basis of learning and memory.

2 ve stress that also exhibit impaired spatial learning and memory.

3 lasticity and are thought to be the basis of learning and memory.

4 ushroom body, a brain structure required for learning and memory.

5 s, altered DG cell composition, and impaired learning and memory.

6 on (LTP) shapes neural circuits and mediates learning and memory.

7 iation, an electrophysiological correlate of learning and memory.

8 ehaviors, and impaired hippocampus-dependent learning and memory.

9 stem cells in vivo, which leads to impaired learning and memory.

10 ive" toward dorsal striatum-based "habitual" learning and memory.

11 most extensively studied cellular model for learning and memory.

12 d with improvements in hippocampal-dependent learning and memory.

13 ces synaptic plasticity that is required for learning and memory.

14 progression, mitochondrial respiration, and learning and memory.

15 plasticity, which is a process important for learning and memory.

16 MKII), a key synaptic signaling molecule for learning and memory.

17 Neuroplastins are essential for learning and memory.

18 ant for synaptic plasticity and, ultimately, learning and memory.

19 rvation of the basal ganglia is important in learning and memory.

20 unctions, such as perception, attention, and learning and memory.

21 ocin and vasopressin are known to facilitate learning and memory.

22 nesis, synapse formation and plasticity, and learning and memory.

23 aptic plasticity and is widely implicated in learning and memory.

24 e the impact of GIRK channels on associative learning and memory.

25 stic, a property thought to be necessary for learning and memory.

26 ritic spines are thought to be essential for learning and memory.

27 ed social behaviour, locomotor activity, and learning and memory.

28 neural pathways that mediate natural reward learning and memory.

29 the hippocampus, a brain area essential for learning and memory.

30 itive-stereotyped behavior, social behavior, learning and memory.

31 tion with AD, but is known to play a role in learning and memory.

32 s synaptic plasticity, neurodevelopment, and learning and memory.

33 ation in the hippocampus and is critical for learning and memory.

34 ions between neurons, is thought to underlie learning and memory.

35 neurocognitive deficits, including those in learning and memory.

36 ) activation, a critical pathway involved in learning and memory.

37 circuitry-brain areas that are important for learning and memory.

38 e associated with severe deficits in spatial learning and memory.

39 ptic plasticity and for the consolidation of learning and memory.

40 egulatory RNAs, and how each might influence learning and memory.

41 regarded as a cellular mechanism underlying learning and memory.

42 ved in many forms of synaptic plasticity and learning and memory.

43 naptic plasticity, a major cellular model of learning and memory.

44 d profound deficits in hippocampus-dependent learning and memory.

45 strength of synaptic changes associated with learning and memory.

46 play important roles in synaptic plasticity, learning and memory.

47 ffects of N. apis or N. ceranae on honey bee learning and memory.

48 ein synthesis, in common with other forms of learning and memory.

49 in synaptic plasticity, which is crucial for learning and memory.

50 t mediate synaptic transmission and underpin learning and memory.

51 and prefrontal cortex (PFC) are critical for learning and memory.

52 tional plasticity of spines and, ultimately, learning and memory.

53 in the mammalian brain and is implicated in learning and memory.

54 e intensity was associated with variation in learning and memory.

55 with cognitive functioning, including verbal learning and memory.

56 fferential effects on spatial and contextual learning and memory.

57 l is crucial for understanding mechanisms of learning and memory.

58 ocampus is thought to play a central role in learning and memory.

59 dendrite morphogenesis, and impairs spatial learning and memory.

60 le proper attention selection and successful learning and memory.

61 nceptualized at a basic level as maladaptive learning and memory.

62 mpal dentate gyrus is critically involved in learning and memory.

63 a brain region of fundamental importance in learning and memory.

64 ntiation (LTP) is critical for understanding learning and memory.

65 A, eCB form a bidirectional system to encode learning and memory.

66 sticity is a cardinal cellular mechanism for learning and memory.

67 ntribute to high cognitive processes such as learning and memory.

68 pression in the complex processes underlying learning and memory.

69 iation and deficits in hippocampus-dependent learning and memory.

70 Drosophila mushroom body, a brain center for learning and memory.

71 d maintenance are of critical importance for learning and memory.

72 ong-term potentiation, which is critical for learning and memory.

73 n dramatic deficits in hippocampal-dependent learning and memory.

74 might influence cognitive functions, such as learning and memory.

75 in locomotion, depression-like behavior, or learning and memory.

76 cade within the brain is crucial for optimal learning and memory.

77 t mechanisms are known to play a key role in learning and memory.

78 processes ranging from muscle contraction to learning and memory.

79 ich provides a compelling cellular model for learning and memory.

80 has been appreciated since early studies on learning and memory.

81 fications in PV+ cells that are required for learning and memory.

82 ong been considered a cellular correlate for learning and memory.

83 icity, is accepted as the cellular basis for learning and memory.

84 portant roles in neurogenesis, as well as in learning and memory.

85 e signal to the nucleus that is critical for learning and memory.

86 erations and, thus, developmental changes in learning and memory.

87 property not limited to neurons involved in learning and memory.

88 an important layer of gene regulation during learning and memory.

89 l for understanding functional mechanisms of learning and memory.

90 ng-dependent LTP (t-LTP), a cellular form of learning and memory.

91 hat modulates neuronal plasticity underlying learning and memory.

92 ssful events have a powerful effect on human learning and memory.

93 tergic neurons and serves a critical role in learning and memory.

94 pus, a vulnerable brain region implicated in learning and memory.

95 ies have yet to examine its function in fear learning and memory.

96 ronal excitability, synaptic plasticity, and learning and memory.

97 CE STATEMENT The hippocampus is required for learning and memory.

98 yed a social behavioral deficit and impaired learning and memory.

99 s) are glycoproteins in the brain central to learning and memory.

100 of the major cellular mechanisms underlying learning and memory.

101 xiety-like behavior, but not the deficits in learning and memory.

102 glutamatergic synapses and is important for learning and memory.

103 s important for reward, motivation, emotion, learning, and memory.

104 NS) and are essential for brain development, learning, and memory.

105 rength necessary for long-term potentiation, learning, and memory.

106 ain and are involved in synaptic plasticity, learning, and memory.

107 g perception, attention, task consolidation, learning, and memory.

108 ion will play a vital role in communication, learning, and memory.

109 including nociception, synaptic plasticity, learning, and memory.

110 ain function, affecting selective attention, learning, and memory.

111 itive pathways regulating neuronal survival, learning, and memory.

112 t solely be explained by general deficits in learning and memory, 2) that there is no uniform decline

113 els of experience-dependent V1 plasticity in learning and memory [6].

114 es inappropriate social behavior with intact learning and memory, a profile reminiscent of high-funct

115 ltrasound stimulation significantly improved learning and memory abilities and morphology in rats wit

116 F344 rats in late middle-age having similar learning and memory abilities were chosen and treated wi

117 DE4B inhibition has the potential to improve learning and memory ability and overall functioning for

118 Dementia is characterized by the loss of learning and memory ability.

119 Verbal learning and memory and attention are most consistently

120 ntered losartan's capacity to rescue spatial learning and memory and blocked losartan's benefits on d

121 al pre-frontal cortex (mPFC) and hippocampal learning and memory and caused increased microglial acti

122 DL is implicated in learning and memory and considered homologous to medial

123 hile allowing for plasticity associated with learning and memory and contribute to regeneration and d

124 ehavior, hyperhedonia, hyperphagia, impaired learning and memory and exaggerated startle responses.

125 nt behaviors in adulthood, including spatial learning and memory and fear conditioning.

126 ronal protein synthesis rates, essential for learning and memory and for neuronal survival.

127 show clear deficits in hippocampus-dependent learning and memory and hippocampal synaptic plasticity.

128 kinase II alpha (CaMKIIalpha) is critical in learning and memory and is synthesized locally in neuron

129 t brain function in the essential process of learning and memory and may be compromised in degenerati

130 hat lithium in therapeutic doses may improve learning and memory and modify the risk of developing de

131 n the dentate gyrus are critical for spatial learning and memory and other hippocampal functions.

132 dle-aged mice enhances hippocampal-dependent learning and memory and restores it to normal performanc

133 status of Robo3.1 in brain regions governing learning and memory and reward.

134 synapse formation provides insight into both learning and memory and the etiology of neurodegenerativ

135 ng-term impairment in specific components of learning and memory and to have differential effects on

136 portant for cell growth and differentiation, learning, and memory and immune cell functions.

137 ds glutamate (excitatory neurotransmitter in learning and memory) and phenylalanine (neurotransmitter

138 s complex results in hyperactivity, impaired learning and memory, and abnormal maturation and mainten

139 the FAD mutation impairs synaptic function, learning and memory, and age-dependent neuronal survival

140 euronal plasticity is the cellular basis for learning and memory, and it is crucial for the refinemen

141 el role for GLRA2 in synaptic plasticity and learning and memory, and link altered glycinergic signal

142 tween hippocampal neurons is associated with learning and memory, and LTP dysfunction is thought to u

143 Theta oscillations are essential for learning and memory, and their generation requires GABAe

144 uences of heightened BLA activation for fear learning and memory, and to specifically identify a mech

145 behavioural phenotype showing impairments in learning and memory, anxiety-like behaviour and sensorim

146 Thus, brain homeostasis is maintained and learning and memory are assured.

147 These results suggest that spatial learning and memory are energized by the release of dopa

148 els to other forms of neuroplasticity and to learning and memory are not known.

149 Learning and memory are severely compromised in dementia

150 As a result, adult learning and memory are thought to result from specific

151 -adrenergic receptors (betaARs), facilitates learning and memory as well as the induction of synaptic

152 AMPAR) trafficking, a molecular substrate of learning and memory, as a probable mechanism for the ant

153 vented anesthesia-induced deficit in spatial learning and memory, as measured by Morris water maze ta

154 -DHA treatment markedly improved the spatial learning and memory, as measured by Morris water maze te

155 found an exacerbation of deficits in spatial learning and memory, as well as in working and associati

156 mitochondrial abnormalities, impairments in learning and memory, as well as synaptic plasticity at a

157 reduces synaptic strength and is relevant to learning and memory, autism, and sensitization to cocain

158 to regulate hippocampal circuit activity and learning and memory behaviors.

159 Neuronal ApoE receptors are linked to learning and memory, but the pathways governing their ab

160 ses for understanding the synaptic basis for learning and memory, but the underlying molecular mechan

161 aloxone/naltrexone are involved in improving learning and memory, but their cellular and molecular me

162 ted that drug tolerance represents a form of learning and memory, but this has not been experimentall

163 Sleep is an essential process that supports learning and memory by acting on synapses through poorly

164 OR) regulates long-term synaptic plasticity, learning, and memory by controlling dendritic protein sy

165 ), salience detection (anterior insula), and learning and memory (caudate and parahippocampal gyrus).

166 Mushroom bodies are the iconic learning and memory centers of insects.

167 ould guide future functional studies of this learning and memory centre.

168 chamber to further investigate the nature of learning and memory changes.

169 23aIN/23aIN mice showed specific deficits in learning and memory compared with Nf1+/+ mice.

170 late synaptic strength and are implicated in learning and memory, consist of several subtypes with di

171 ognitive enhancement across several tests of learning and memory, consistent with synaptic changes in

172 multifaceted functions in brain development, learning and memory consolidation by selectively elimina

173 ocampus, a brain region that is critical for learning and memory, contains a large number of neurons

174 e indicating that exposure to stress affects learning and memory, decision making and emotional respo

175 nd risk-taking behaviors, hyperactivity, and learning and memory defects.

176 ippocampus and cortex neurodegeneration, and learning and memory defects.

177 Hippocampus-based learning and memory deficits are key symptoms of FASD.

178 out mice, we show that hippocampal-dependent learning and memory deficits in CDKL5 deficiency have or

179 We find spatial learning and memory deficits in FE65-KO and FE65L1-KO mi

180 letion in the dorsal hippocampus resulted in learning and memory deficits in fear conditioning, where

181 mple sizes to make these assays sensitive to learning and memory deficits in humans with MCI-AD and i

182 ntiation (LTP) and aged mice display spatial learning and memory deficits that are absent from young

183 erneurons that correlated with the extent of learning and memory deficits, as determined by Morris wa

184 atively regulates spine numbers resulting in learning and memory deficits, possibly as a result of it

185 e adult brain prevents hippocampus-dependent learning and memory deficits, restores motor function af

186 e brain Abeta, leading to aggravated spatial learning and memory deficits, thus emphasizing the impor

187 dent hilar GABAergic interneuron decline and learning and memory deficits, when examined at 16 month

188 disease, neprilysin overexpression improves learning and memory deficits, whereas neprilysin deficie

189 disease (AD) patients with the emergence of learning and memory deficits, yet a clear understanding

190 itory effects on neurogenesis and associated learning and memory deficits.

191 or 4 weeks before and during MWM rescued the learning and memory deficits.

192 , enhances long-term depression, and induces learning and memory deficits.

193 sible for synapse damage, neurodegeneration, learning, and memory deficits in AD.

194 Learning and memory depend on the ability of synapses to

195 SIGNIFICANCE STATEMENT: Learning and memory depend on the ability of synapses to

196 , without affecting performance in a spatial learning- and memory-dependent task.

197 naptic plasticity, and hippocampal-dependent learning and memory due to a failure in learning-induced

198 s a potential therapeutic to reverse chronic learning and memory dysfunction and deficits in hippocam

199 ally active and are thought to contribute to learning and memory, especially during their maturation

200 nitially spared in this syndrome, the subtle learning and memory features of PPA and their neuropatho

201 9, and 12 months of age to evaluate spatial learning and memory, followed by histologic assessment o

202 Morris water maze (a common test of spatial learning and memory for rodents) that is designed for us

203 he honeybee is a model organism for studying learning and memory formation and its underlying molecul

204 unction, including cortical contributions to learning and memory formation, require appropriate exper

205 to all aspects of brain function, including learning and memory formation.

206 Here, we investigated the learning and memory function of CaMK2N1 by knocking-down

207 rcuit of temporal lobe areas associated with learning and memory function.

208 in T1R3KO mice together with alterations in learning and memory functions as well as sociability def

209 gh regulation of cofilin-1, and in executing learning and memory functions.

210 The neurobiology of learning and memory has been mainly studied by focusing

211 In many animal species, learning and memory have been found to play important ro

212 to address the question of how variation in learning and memory impacts their performance in natural

213 itor BAY60-7550 (BAY) affected Abeta-induced learning and memory impairment in two classic rodent mod

214 ice; however, the bEKO mice did not have the learning and memory impairment observed in ApoE KO mice.

215 (KI) mice, human apoE4 causes age-dependent learning and memory impairments and degeneration of GABA

216 Learning and memory impairments are common in traumatic

217 ultimately reveal a key mechanism underlying learning and memory impairments of PNN-associated neurod

218 E4 in GABAergic interneurons, which prevents learning and memory impairments, rescued SWR-associated

219 WRs critically contributes to apoE4-mediated learning and memory impairments.

220 effective treatments to improve TBI-induced learning and memory impairments.

221 strated preserved hippocampus-dependent fear learning and memory, improved motor function recovery, a

222 and impaired synaptic plasticity and spatial learning and memory in 3-mo-old mice.

223 ejuvenate adult brain plasticity and restore learning and memory in a variety of cognitive disorders.

224 and caused selective alterations in spatial learning and memory in adult mice.

225 rations in various brain regions, as well as learning and memory in adults.

226 When EI balance is disturbed during learning and memory in animal models, it can be restabil

227 y identified neuropathologic associations of learning and memory in autopsy-confirmed cases of PPA.

228 sociated with pronounced deficits in spatial learning and memory in context-dependent fear conditioni

229 ttenuate ketamine-induced deficits in verbal learning and memory in humans.

230 cently shown to rescue hippocampus-dependent learning and memory in Mecp2(+/-) (Rett) mice, also resc

231 t-term synaptic plasticity, LTP, and spatial learning and memory in mice.

232 for fine-tuning Ras/ERK signaling as well as learning and memory in mice.

233 frequently used behavioral assay of spatial learning and memory in rodents - translates to humans.

234 t commonly used techniques to assess spatial learning and memory in rodents.

235 ing development and for synaptic plasticity, learning and memory in the adult.

236 a4(-/-) mice displayed prominent deficits in learning and memory in the contextual fear-conditioning

237 ression of synaptic proteins associated with learning and memory in the DG.

238 ue synaptic loss, it does completely restore learning and memory in the mice, suggesting that both CN

239 alleviated deficits in synaptic plasticity, learning, and memory in diabetic mice.

240 plants, neonicotinoids can affect foraging, learning, and memory in worker bees.

241 c plasticity, the major neural substrate for learning and memory, in various brain areas.

242 ne is critical for many processes that drive learning and memory, including motivation, prediction er

243 utamatergic synaptic plasticity required for learning and memory, includingN-methyl-d-aspartate recep

244 tudied in caste differentiation, its role in learning and memory is not clear in honeybees.

245 structure known to be critical in processing learning and memory, is one of the first and most heavil

246 , the postnatal loss of Mef2c did not impact learning and memory, long-term potentiation, or social a

247 timulating the neural circuits that underlie learning and memory might provide a more promising route

248 amental problem of the science of human fear learning and memory, namely whether fear learning via ex

249 initiation factor 2, which is implicated in learning and memory, neurodegenerative diseases, and can

250 ss, implying that DNA methylation can affect learning and memory of honeybees by regulating other epi

251 nefits of the neurotrophic agent LM11A-31 on learning and memory outcomes after traumatic brain injur

252 unit in neuronal circuits, are critical for learning and memory, perception, thinking, and reaction.

253 decline in social functioning, lower verbal learning and memory performance, slower speed of process

254 Learning and memory plays an important role in host pref

255 echanisms that normally serve reward-related learning and memory, primarily by evoking changes in glu

256 These cues are formed by normal learning and memory principles, and the understanding of

257 ide DNA methylation changes during olfactory learning and memory process in A. mellifera using whole

258 ent of DNA methylation in honeybee olfactory learning and memory process.

259 c are critically involved in reward-relevant learning and memory processes and that nuclear HDAC5 lim

260 local dendritic translation, participates in learning and memory processes as well as in mechanisms u

261 ations, as repeated stress generally impairs learning and memory processes unrelated to stressful exp

262 xcitability have been shown to underlie many learning and memory processes, little is known about the

263 en accorded an important role in hippocampal learning and memory processes.

264 REB), a transcriptional factor involved with learning and memory processes.

265 ighly expressed in brain regions involved in learning and memory processes.

266 scape may cause impairments in regulation of learning and memory-related genes within the aged hippoc

267 Learning and memory rely on dopamine and downstream cAMP

268 g forms of synaptic plasticity that underlie learning and memory require new transcription and transl

269 olinergic and GABAergic systems during taste learning and memory retrieval.

270 h OSAS, which correlates with a lower verbal learning and memory score.

271 g microcircuit mechanism underlying impaired learning and memory.SIGNIFICANCE STATEMENT Cyclin-depend

272 well as activity, anxiety-related behavior, learning and memory, socialization, and depressive-like

273 s associated with feeding, courtship, sleep, learning and memory, stress, addiction, and social inter

274 se DMGs, many are critical genes involved in learning and memory, such as Creb, GABA B R and Ip3k, in

275 associated with extreme deficits in spatial learning and memory, suggesting that TRIM9-directed neur

276 tion of spine numbers with a dissociation of learning and memory, synaptic plasticity, and measures o

277 tressor-induced behavior, and performance in learning and memory tasks.

278 of hippocampus, a region involved in spatial learning and memory, tau pathology is associated with sp

279 performed a dual-task paradigm and a verbal learning and memory test during and out of symptomatic a

280 outperform wild-type controls in associative learning and memory tests.

281 s performance on behavioral tasks of spatial learning and memory that are impaired by isoflurane expo

282 ith lower mean performance on one measure of learning and memory that requires mental control and cog

283 and how they relate to general processes of learning and memory, the review discusses how aging affe

284 ave shown that three brain areas involved in learning and memory--the hippocampus, amygdala and prefr

285 ke and sleep SWRs both contribute to spatial learning and memory, thought to be mediated by the coord

286 campal subgranular zone (SGZ) is involved in learning and memory throughout life but declines with ag

287 he potential epidemiological consequences of learning and memory to a largely speculative extent.

288 Learning and memory, to a large extent, depend on functi

289 In human adults, learning and memory under acute stress are characterized

290 e beneficial effect of naltrexone on spatial learning and memory under normal conditions appears to b

291 ctioning, attention, verbal and visuospatial learning and memory, visuospatial perception, inhibitory

292 is thought to be the cellular equivalent of learning and memory, was impaired.

293 Spatial learning and memory were assessed using Morris water maz

294 n, deficits in hippocampal-dependent spatial learning and memory were exaggerated in E4 mice.

295 ed and information processing, attention and learning and memory were examined with the Trail Making

296 hippocampus is a brain region essential for learning and memory, which has been involved in the mech

297 halamus is involved in a form of nutritional learning and memory, which is critical for determining r

298 evidence suggests that dopamine may modulate learning and memory with important implications for unde

299 ide exposure can have appreciable impacts on learning and memory, with potential implications for ess

300 global cognition, attention, working memory, learning, and memory, with the exception of nonverbal me