ライフサイエンスコーパス: lectin

1 ely 26kDa) was purified and characterized as lectin.

2 cytes are also recruited in response to this lectin.

3 terial Fap2, which functions as a Gal-GalNAc lectin.

4 first biosensor for this application using a lectin.

5 ng side chains that might bind this class of lectin.

6 o the carbohydrate recognition domain of the lectin.

7 lar basis for the strict specificity of this lectin.

8 differentiation marker lotus tetragonolobus lectin.

9 argely absent in the double-domain bulb-type lectins.

10 ed those usually measured for GlcNAc-binding lectins.

11 related to certain eukaryotic fucose-binding lectins.

12 nd subsequent binding assays with label-free lectins.

13 otein belonging to the superfamily of C-type lectins.

14 libraries of free (unmodified) HMOs against lectins.

15 d 18 (PARC), and sialic acid-binding Ig-like lectin 14 (SIG14) were significantly modulated in all th

16 omplement activation through mannose-binding lectin 2.

17 ocus at SIGLEC5 (sialic acid binding Ig-like lectin 5) and a chromosomal region downstream of the DEF

18 ysis of glycan-array data, we found that the lectin AAL had higher binding where fucose groups are di

19 for the single- and double-domain bulb-type lectins abundant in plant genomes.

20 OS-9, an ER-resident lectin, acts downstream of Grp94 to further recognize mi

21 eparable components: the pathogenic agent, a lectin/adhesin and a glycan ligand.

22 were enriched by detergent phase separation, lectin affinity chromatography, and SDS-PAGE.

23 mitation, we developed an approach that uses lectin affinity chromatography, ion-exchange chromatogra

24 olyethylene glycol precipitation followed by lectin affinity chromatography.

25 E1E2 can be purified using Galanthis nivalis lectin agarose (GNA), but this technique is suboptimal f

26 ssed classic germinal center markers, peanut lectin (agglutinin) and GL-7.

27 he nascent phagosomes that harbor Gal/GalNAc lectin and actin.

28 H) exert a tight regulation of the classical/lectin and alternative pathways of complement activation

29 lectin (Gal)-3 is a beta-galactoside-binding lectin and currently intensely studied as a biomarker in

30 Here we report the structure of the lectin and EGF domains of L-selectin bound to a fucose m

31 on with only modest architectural changes in lectin and esterase domains; and (iii) a single, inconsp

32 Knowledge of lectin and glycosidase specificities is fundamental to t

33 the precise determination and description of lectin and glycosidase specificities.

34 When the lectin and pilin domains are separated under shear stres

35 C activation via Macrophage-inducible C-type lectin and TLR7/8 representing a novel approach to enhan

36 nowledge of glycan binding of human pathogen lectins and adhesins.

37 ell-defined glycan-binding proteins, such as lectins and antibodies that recognize specific determina

38 ion causes deficiencies in intestinal C-type lectins and antimicrobial peptides, which leads to dysbi

39 proteins, promotes their association with ER lectins and associated chaperones, and prevents prematur

40 Lectins and chitin are secreted to form the cyst wall, a

41 vation pathways (classical, alternative, and lectin) and a terminal cytolytic pathway common to all.

42 nitiating mechanisms known as the classical, lectin, and alternative pathways.

43 t is activated by three pathways: classical, lectin, and alternative.

44 Hvt alone or in combination with onion leaf lectin are resistant to Phenacoccus solenopsis (cotton m

45 The active states of most bulb-type lectins are dimeric and it is thus important to elucidat

46 sidues at the interface of dimeric bulb-type lectins are largely absent in the double-domain bulb-typ

47 The bulb-type lectins are proteins consist of three sequential beta-sh

48 A yet unidentified IgE-binding lectin associated with A549 EC is implicated after disco

49 The serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice c

50 rect cleavage of native C3 by mannan-binding lectin-associated serine protease-2 bound to LP-activati

51 ectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native

52 e is dependent on LP-specific mannan-binding lectin-associated serine protease-2.

53 Moreover, a lectin-based nanoprobe was designed by noncovalent assem

54 r fast in situ peptide MALDI sequencing; the lectin-based protein chips showed the ability to enrich

55 ttributable to disease-associated mutations, lectin binding and mass spectrometry analysis revealed t

56 In contrast, in the case of lectin binding on glycopolymer brushes (3.4 nm thick), w

57 Thus, a glycan-lectin binding pair of SugarBindDB can lead to the ident

58 A new algorithm to evaluate changes in lectin binding upon treatment with exoglycosidases ident

59 ria-chips were developed for the analysis of lectin-binding kinetics and affinity.

60 Intelectins (X-type lectins), broadly distributed throughout chordates, have

61 Although the FimH lectin can adopt three distinct conformations, the evalu

62 we have demonstrated how the closely related lectins can be discerned and quantified in a single assa

63 Notably, for each lectin, CaR-ESI-MS screening required <1 h to complete a

64 omplex natural glycosaminoglycans (GAG), and lectins/carbohydrate binding proteins using matrix-assis

65 lude the discovery of an unexpected role for lectin CD22 as a B-cell homing receptor GALT, and identi

66 hat gut DCs express mRNA encoding for C-type lectin (CLEC) 7A, CLEC9A, CLEC12A, and CLEC4N.

67 thepsins, and the natural killer (NK)/C-type lectin (CLEC) complex [6-12].

68 We show that the group 14 C-type lectins CLEC14A, CD93 and CD248 directly bind to MMRN2 a

69 molecular function of the cartilage-specific lectin CLEC3A and show that CLEC3A binds to plasminogen

70 described how the recently discovered C-type lectin collectin-11 (CL-11, also known as CL-K1 and enco

71 Given these results, we conclude that lectin complement pathway activation triggered by ligand

72 at sites of ischemic stress, activating the lectin complement pathway and directing the innate immun

73 revealed that cell-bound CL-11 required the lectin complement pathway-associated protease MASP-2 to

74 cules can however activate the classical and lectin complement pathways, rendering this species still

75 r, we propose a potential mechanism for this lectin complex formation where coevolving polar residues

76 abels were recognized by the mannose-binding lectin, Con A, and the biotin-binding protein avidin-per

77 ion level on their surfaces was probed using lectin concanavalin A (Con A) from Canavalia ensiformis.

78 , antibody-conjugated SiO2 nanoparticles and lectin-conjugated magnetic Fe3O4 nanoparticles, to achie

79 Likewise, this lectin controls T cell and B cell compartments by modula

80 An association between mannose-binding lectin deficiency and anti-Saccharomyces cerevisiae anti

81 Here, we report that C-type lectin dendritic cell (DC) immunoreceptor (DCIR), a key

82 These findings point to a lectin-dependent activation of basophil requiring IgE bu

83 ct to mutant CALR function, we show that its lectin-dependent function is required for binding to MPL

84 vel QCM approach involves capture of NTHi on lectin-derivatized chips followed by formaldehyde fixati

85 Cells not expressing the lectin discoidin I or moving on discoidin I-coated subst

86 s, we generated mutants of the isolated FimH lectin domain and characterized their thermodynamic, kin

87 n a predicted long-loop region in the C-type lectin domain and is abrogated by mutation within the do

88 o-state model in which ligand binding to the lectin domain closes loop 83-89 around the Ca(2+) coordi

89 -glycosylation, consist of a catalytic and a lectin domain connected by a flexible linker.

90 The C-type lectin domain containing group 14 family members CLEC14A

91 ure; p=2.3x10-7) and was annotated to C-Type Lectin Domain Family 11, Member A (CLEC11A), which funct

92 C-type lectin domain family 3 member A (CLEC3A) is a poorly cha

93 oluble beta-glucans, which antagonize C-type lectin domain family 7 member A (CLEC7A or DECTIN1) sign

94 de shows that the GalNAc-binding site of its lectin domain is rotated relative to the homologous GalN

95 The extracellular lectin domain of LecRK-I.8 binds NAD(+) with a dissociat

96 al for the allosteric propagation within the lectin domain that would otherwise be conformationally r

97 teric control over binding of the N-terminal lectin domain to mannosylated ligands on host cells.

98 ther in the absence of CD45 or when the CD22 lectin domain was mutated.

99 flexible linker dictates the rotation of the lectin domain, thus modulating the GalNAc-Ts' long-range

100 erized a novel Cryptosporidium parvum C-type lectin domain-containing mucin-like glycoprotein, CpClec

101 lNAc-O-Ser/Thr) preferences modulated by the lectin domain.

102 We evaluated the extrinsic effect of lectin domains (beta-trefoil fold) of polypeptide GalNAc

103 rfhSP-D, containing homotrimeric neck and lectin domains, was expressed in Escherichia coli BL21(l

104 vity), irrespective of linker length between lectin domains.

105 he immune inhibitory role of this endogenous lectin during Y. enterocolitica infection.

106 Consistent with a regulatory role for this lectin during Y. enterocolitica pathogenesis, mice lacki

107 without triggering allostery that opens the lectin/EGF domain hinge.

108 is triggers further allostery that opens the lectin/EGF domain hinge.

109 ycosites with a deeper coverage (compared to lectin enrichment) and improves large-scale N-glycoprote

110 this study suggest that HMO specificities of lectins established using microarrays may not accurately

111 Collectin-11, a soluble C-type lectin expressed in renal tissue, has been implicated as

112 Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells.

113 rker sialic acid-binding immunoglobulin-like lectin F and overproduced TNF and IL-6 through increased

114 e demonstrated that mice deficient in C-type lectin family 14 member A (CLEC14A) display enhanced ang

115 alNAc) on cancer cells using a fusobacterial lectin, Fap2.

116 es in the UPR signature included chaperones, lectins, foldases, and N-linked glycosylation enzymes.

117 herefore, Cyt-CVNH may qualify as a valuable lectin for potential microbicidal use.

118 Thus, UEA-I and PNA appear to be excellent lectins for pancreatic acinar cell purification.

119 st to the dimer complex of two single-domain lectins formed via protein-protein interactions, the dou

120 arbohydrate-binding module, a fucose-binding lectin from Ralstonia solanacearum, and human norovirus

121 The discovery that two aspects of lectin functionality (trans- versus cis-activity) respon

122 This novel assay format involves using lectin functionalized magnetic nanoparticles for capture

123 antage of the cell-specific aptamer, and the lectin-functionalized gold nanoparticles acting as both

124 tein-protein interactions, the double-domain lectin fuses two single-domain proteins into one protein

125 We found that dectin 1 can ligate the lectin galectin 9 in mouse and human PDA, which results

126 The beta-galactoside-binding animal lectin galectin-3 is predominantly expressed by activate

127 se factors become upregulated, including the lectin galectin-3.

128 number tandem repeats (VNTRs) that bind the lectin galectin-3; galectin-3 siRNA but not galectin-1 s

129 -1BB also can bind to the tandem repeat-type lectin galectin-9 (Gal-9), and signaling through mouse (

130 specific glycan sulfation in modulating this lectin-glycan interaction, and will enable the rational

131 ated protein-protein interaction, that is, a lectin-glycoprotein interaction, via substructure search

132 ectin receptor) or DNGR-1 (dendritic cell NK lectin group receptor-1) is preferentially expressed by

133 Ulex Europaeus Agglutinin I (UEA-I) lectin has been used to label and isolate acinar cells f

134 iomimetic carbohydrate receptors ("synthetic lectins") have potential as agents for biological resear

135 ctivatable probes, antibodies, peptides, and lectins, have been administered in preclinical and clini

136 CD169, a sialic acid-binding lectin, helps retain the cells within the sinus, prevent

137 serum glycopattern and the maackia amurensis lectin-II binding glycoproteins (MBGs) in 65 children wi

138 e HMOs of known concentration for binding to lectins in vitro.

139 -web spider) neurotoxin (Hvt) and onion leaf lectin, in tobacco (Nicotiana tabacum).

140 or comprehensive and quantitative studies of lectin interactions with glycolipids in native-like, mem

141 human galectin-3, a beta-galactoside-binding lectin involved in immune regulation and antimicrobial d

142 for screening carbohydrate libraries against lectins is described.

143 ation of immune cells (but not B cells) with lectins is widely known.

144 cognate CTLR keratinocyte-associated C-type lectin (KACL) selectively expressed by human keratinocyt

145 rks were visualized with FITC conjugated BSI-lectin labeling and arteriole diameters were compared be

146 ctions were at the core of the transition in lectin ligand and esterase substrate specificity; (ii) i

147 Two lectin-like "head" domains of CD23 bind to IgE-Fc with a

148 tors include members of the NKRP1 and C-type lectin-like 2 (CLEC2) gene families, which constitute ge

149 It possesses a C-type lectin-like domain (CTLD) followed by a poorly character

150 Chemically induced shedding of the lectin-like domain of TBM resulted in significantly incr

151 n effect that appears to be dependent on the lectin-like domain of TBM.

152 The TIP peptide, a mimic of the lectin-like domain of TNF, activates ENaC by binding to

153 dditional antiparallel beta-sheet carrying a lectin-like domain that could be responsible for EPS bin

154 first characterization of the orphan C-type lectin-like molecule Clr-a encoded by the Clec2e gene in

155 dant function of these highly related C-type lectin-like molecules in the context of intestinal immun

156 nvolves NK gene complex (NKC)-encoded C-type lectin-like molecules such as NKG2D and Nkrp1 receptors.

157 perties of cardiomyocytes in relation to the lectin-like oxidized LDL receptor (LOX-1).

158 hown to activate platelets via its receptor, lectin-like oxidized LDL receptor-1 (LOX-1), and alphabe

159 Lectin-like oxidized low-density lipoprotein receptor-1

160 teomic analyses of mucus have identified the lectin-like protein ZG16 (zymogen granulae protein 16) a

161 NKp65 is an activating human C-type lectin-like receptor (CTLR) triggering cellular cytotoxi

162 C-type lectin-like receptor 2 (CLEC-2) is a platelet receptor t

163 Platelet C-type lectin-like receptor 2 (CLEC-2) is known to maintain the

164 latelet formation by interaction with C-type lectin-like receptor 2 (CLEC-2).

165 ein VI (GPVI) and podoplanin receptor C-type lectin-like receptor 2 (CLEC2) are receptors implicated

166 igh expression of the inhibitory killer cell lectin-like receptor G1 (KLRG1) in individuals >70 y.

167 The mouse C-type lectin-like receptor Nkrp1g was previously shown to form

168 Rhodocytin, an agonist of the C-type lectin-like receptor-2 (CLEC-2), elicits powerful platel

169 gene complex-encoded immunomodulatory C-type lectin-like receptors include members of the NKRP1 and C

170 ogen recognition receptors, including C-type lectin-like receptors, TLRs, and nucleotide oligomerizat

171 udy was to reveal a possible role of NKR-P1A/lectin-like transcript 1 (LLT1) interaction in NK cell-m

172 The innate lectin-like transcript 1 (LLT1) is known to be expressed

173 LLT1 (lectin-like transcript 1), the ligand for CD161a, was ov

174 planin and collagen/fibrin receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI), respe

175 The L-type lectin LMAN2 (also known as VIP36) appears to be specifi

176 In the initial step of colonization, FimH, a lectin located at the tip of bacterial type 1 pili, inte

177 were determined for the first time using the lectins MAA and SNA-I.

178 sialidases (neuraminidase and sialidase S), lectins (Maakia amurensislectin andSambucus nigralectin)

179 ere compared by using lectin microarrays and lectin-magnetic particle conjugate-assisted LC-MS/MS ana

180 elium in human dysplasia suggests that these lectins may enable more sensitive detection of disease i

181 Measurement of mannan binding lectin (MBL) antigenic level and activity revealed MBL d

182 ogenous complement inhibitor, mannan-binding lectin (MBL)-associated protein (MAp)44, in regulating t

183 was shown that mice lacking mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1) and M

184 C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2) gene polymorphisms of liver donors were si

185 to MBL protects DENV against mannose-binding lectin-mediated neutralization by the lectin pathway of

186 (Man) headgroups, a known routing signal for lectin-mediated transport processes, was constructed via

187 The macrophage galactose-type lectin (MGL) is a C-type lectin that binds to glycoprote

188 eloping (TD) children were compared by using lectin microarrays and lectin-magnetic particle conjugat

189 Identification of the C-type lectin Mincle as one of the receptors underlying the rem

190 r results reveal a pathway by which a C-type lectin modulates the equilibrium between infection-drive

191 ted on a series of covalent linkages between lectin molecules and a cysteine layer immobilized over g

192 gut microbiome in mosquitoes utilizes C-type lectins (mosGCTLs) to evade the bactericidal capacity of

193 ce, and characterized as an l-fucose-binding lectin, named P. luminescens lectin (PLL).

194 ain-selective binding of three innate immune lectins, namely, surfactant protein D, human galectin-8,

195 The lectin nanoelectrode showed a good repeatability (1.24%

196 Furthermore, lotus tetragonolobus lectin-negative/p-Creb-positive cyst segments (re)-expre

197 vestigated whether sCD93, a group XIV c-type lectin of the endosialin family, plays a role in metabol

198 Ebulin f and SELfd are two lectins of Sambucus ebulus L. that show different stabil

199 Dectin-2, a C-type lectin on macrophages and other cells of the innate immu

200 d galectin-3 and in causing retention of the lectin on the epithelial cell surface.

201 al substrate, offering opportunities for new lectin or enzyme inhibitors.

202 ecognition receptors or carbohydrate binding lectins or biomachinery enzymes.

203 native or exposed features using a panel of lectins or glycan-binding reagents.

204 Sialic acid-recognizing Ig superfamily lectins or Siglecs are a family of cell surface proteins

205 tion of the complement system via classical, lectin, or alternative pathways generates anaphylatoxins

206 he nature of physiologically relevant glycan/lectin pairing.

207 inding parameters obtained for selected NTHi-lectin pairs provide further insights into the interacti

208 loped and profiled for glycosylation using a lectin panel with a wide range of carbohydrate specifici

209 thway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central even

210 attern recognition molecules (PRMs) from the lectin pathway bind CC and function as an upstream innat

211 Lectin pathway effector enzyme mannan-binding lectin-ass

212 inly by the alternative pathway, whereas the lectin pathway is also activated in those with wild-type

213 ive complement pathways, but the role of the lectin pathway is unknown.

214 inding lectin-mediated neutralization by the lectin pathway of complement activation.

215 SP-2 and MASP-1 have a greater effect on the lectin pathway than the more potent inhibition of only C

216 n in vivo, especially for activation via the lectin pathway.

217 vation through the classical and the related lectin pathway.

218 The classical and lectin pathways are initiated by the C1r/C1s (classical)

219 mportant for the classical, alternative, and lectin pathways of complement activation, and its cleava

220 that negatively regulates the classical and lectin pathways of complement to protect human tissue fr

221 ion of the complement system's classical and lectin pathways, which are important constituents of inn

222 ing no inhibitory effect on the classical or lectin pathways.

223 omplement pathway but not the alternative or lectin pathways.

224 s activated by a non-LPS stimulus, the plant lectin PHA.

225 Lectins play important roles in infections by pathogenic

226 -fucose-binding lectin, named P. luminescens lectin (PLL).

227 nd structural analyses of the P. luminescens lectin PllA have disclosed the structural basis for PllA

228 sidues, blocking interaction with the midgut lectin PpGalec, thereby leading to parasite detachment a

229 sidue ancestral motifs that form five-bladed lectin propellers via oligomeric assembly.

230 y the C1r/C1s (classical) and MASP-1/MASP-2 (lectin) proteases.

231 Moreover, network analysis on bulb-type lectin proteins show that these same polar residues have

232 , trehalose dimycolate, activates the C-type lectin receptor (CLR) Mincle.

233 TLRA/C-type lectin receptor agonist combinations were screened for e

234 Here, we show that the C-type lectin receptor CD69 controls tTreg cell development and

235 e, we found that the FcRgamma-coupled C-type lectin receptor DCAR (dendritic cell immunoactivating re

236 Many members of the C-type lectin receptor family serve as pattern recognition rece

237 n profile of all KIR family genes and C-type lectin receptor genes using RNA sequencing on NKTCL case

238 Here, we identify a lectin receptor kinase (LecRK), LecRK-I.8, as a potentia

239 human and murine forms of the myeloid C-type lectin receptor langerin for simple and complex ligands

240 utrophils elicited in the presence of C-type lectin receptor ligands have an increased ability to pro

241 vely recognized by Mincle (Clec4e), a C-type lectin receptor of the innate immune system that is stro

242 rt, we demonstrate that expression of C-type lectin receptor scavenger receptor-AI (SR-AI) is crucial

243 occurs upon engagement of Dectin-1, a C-type lectin receptor that signals via spleen tyrosine kinase

244 Clec9a (C-type lectin receptor) or DNGR-1 (dendritic cell NK lectin gro

245 Here, we identified functions of one C-type lectin receptor, CLEC12A, in facilitating DC binding and

246 we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially modula

247 ual activation of newborn DCs via the C-type lectin receptor, macrophage-inducible C-type lectin (tre

248 ined the mechanism by which Mincle, a C-type lectin receptor, regulates NET formation.

249 tly higher induction of CD23, a novel C-type lectin receptor, through NFATc1-mediated regulation of t

250 Although C-type lectin receptor- and Toll-like receptor-induced signalin

251 t spores and depends upon Dectin-1, a C-type lectin receptor.

252 everal spleen tyrosine kinase-coupled C-type lectin receptors (CLRs) have emerged as important patter

253 In this context, endocytic C-type lectin receptors are attractive targeting molecules.

254 Our results demonstrate that lectin receptors can potentially function as eNAD(+)-bin

255 PAR)-2, Toll-like receptor (TLR), and C-type lectin receptors have been suggested to be important for

256 have previously shown that different C-type lectin receptors on DCs play a major role in allergen re

257 C-type lectin receptors play important roles in immune cell int

258 C-type lectin receptors sense a diversity of endogenous and exo

259 Therein, the endocytic C-type lectin receptors serve as pattern recognition receptors,

260 specific compartments is regulated by C-type lectin receptors that recognize glycan structures.

261 activity and parasite growth involved C-type lectin receptors, because mannose injection decreased ar

262 damaged epithelium via expression of C-type lectin receptors, many of which signal through the Syk s

263 c expression pattern was observed for C-type lectin receptors.

264 ded to an altered ileal expression of C-type lectins Reg3gamma and Reg3beta, and of interleukin 22.

265 l antimicrobial response, such as the C-type lectins Reg3gamma and Reg3beta.

266 at the level of adhesion, the importance of lectins remains unknown.

267 n of synthetic alpha(1-6)mannans gain better lectin's binding affinity.

268 ocumented association, identification of the lectin's physiological ligand and, accordingly, biologic

269 CD22, a sialic acid-binding Ig-type lectin (Siglec) family member, is an inhibitory corecept

270 cell inhibitory sialic acid-binding Ig-like lectin (Siglec) receptors, and enhanced binding to the N

271 is a sialic acid-binding immunoglobulin-like lectin (Siglec) that is highly expressed on B-cells and

272 Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a cell-surface protein expressed se

273 CD22 and sialic acid-binding Ig-like lectin (Siglec)-G are members of the Siglec family of in

274 tain Sialic-acid-binding immunoglobulin-like-lectins (siglecs) are expressed in human pancreatic isle

275 The lectin SNA showed gradations in binding based on the len

276 C. albicans by Dectin-1, a C-type signaling lectin specific for beta-(1,3)-glucan, is important for

277 mass, and approximately 10 pM for the glycan/lectins studied here.

278 In this study, we introduce the lectin Tetragonolobus purpureas agglutinin (TPA) as a no

279 hage galactose-type lectin (MGL) is a C-type lectin that binds to glycoproteins expressing terminal N

280 a ribosome-inactivating protein, and RTB, a lectin that facilitates receptor-mediated uptake into ma

281 sults indicate that CpClec is a novel C-type lectin that mediates C. parvum attachment and infection

282 REM2 mutants are also efficiently bound by a lectin that recognizes O-glycans added in the ER-Golgi i

283 eria floribunda agglutinin (WFA) is a legume lectin that recognizes terminal N-acetylgalactosaminides

284 harbors the gene plu2096, coding for a novel lectin that we named PllA.

285 Galectins are a family of lectins that bind beta-galactosides through their conser

286 to a new group of bacterial fucose-specific lectins that have no similarity to known bacterial fucos

287 rk of a family of adhesion/growth-regulatory lectins, that is, galectins, we tested the hypothesis th

288 el of GDS aggregation by a tetravalent model lectin: the leguminous agglutinin Con A, which is struct

289 a mixture, into PDs and screened against two lectins: the B subunit homopentamer of cholera toxin (CT

290 lectin receptor, macrophage-inducible C-type lectin (trehalose-6,6-dibehenate), and TLR7/8 (R848) gre

291 In vitro, the lectin was secreted and it bound to osteoarthritic chond

292 y for quantifying the affinities of HMOs for lectins was established from the agreement found between

293 Through the use of vegetal lectins, we managed to take advantage of the markedly at

294 of selected bacteria by culture, and C-type lectins were assessed in ileal tissues by reverse transc

295 Both lectins were quantified in a sandwich immunoassay-like s

296 that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes

297 Cratylia mollis is a lectin with high finity to fetuin, and used here to diff

298 tial factors for functional pairing of human lectins with counterreceptors.

299 Galectin-3 (Gal-3) is a carbohydrate binding lectin, with multiple roles in inflammatory diseases and

300 Xenopus laevis embryonic epidermal lectin (XEEL), an intelectin secreted into environmental