ライフサイエンスコーパス: lectin receptor

1 l antibody or delivered via DC-SIGN, another lectin receptor.

2 esting stimulation via a dendritic cell (DC) lectin receptor.

3 t spores and depends upon Dectin-1, a C-type lectin receptor.

4 inding is mediated by a porcine Kupffer cell lectin receptor.

5 ens to dendritic cells (DCs) through various lectin receptors.

6 tein-specific N-glycan ligand for pancreatic lectin receptors.

7 2p13.1 to p13.2) which contains genes for NK lectin receptors.

8 r integrin and minor roles for scavenger and lectin receptors.

9 us expression of sucrase-isomaltase and most lectin receptors.

10 c expression pattern was observed for C-type lectin receptors.

11 n and, thus, likely to be mediated by C-type lectin receptors.

12 The interaction of C-type lectin receptor 2 (CLEC-2) on platelets with Podoplanin

13 TLRA/C-type lectin receptor agonist combinations were screened for e

14 at distinct combinations of TLRAs and C-type lectin receptor agonists may enhance Th1 responses of ne

15 s the simplest, single domain, type I C-type lectin receptor and showed it was expressed mainly on th

16 y unrecognized link between a myeloid C-type lectin receptor and Th2 immunity.

17 n the signaling cascade downstream of C-type lectin receptors and as critical mediators of the anti-f

18 strated that although mannose-binding C-type lectin receptors and CD4 are the principal receptors for

19 ptors, including Toll-like receptors, C-type lectin receptors and NOD-like receptors.

20 exhibited a restricted repertoire of C-type lectin receptors and relied on CD4 for uptake of Env.

21 d member of the "Dectin-2 cluster" of C-type lectin receptors and was originally thought to be expres

22 [IL]-10, IL-1RA, CD163, scavenger and C-type lectin receptors) and collagen genes, whereas they were

23 ti-fungal innate immune signaling via C-type lectin receptors, and several immune-related disorders a

24 Although C-type lectin receptor- and Toll-like receptor-induced signalin

25 In this context, endocytic C-type lectin receptors are attractive targeting molecules.

26 tionalized with antibody, ss-DNA, aptamer or lectin receptors, are particularly useful for direct det

27 activity and parasite growth involved C-type lectin receptors, because mannose injection decreased ar

28 The C-type lectin receptor blood dendritic cell Ag 2 (BDCA2) is exp

29 ractions with CD4 and mannose-binding C-type lectin receptors, but not with the chemokine receptors C

30 Our results demonstrate that lectin receptors can potentially function as eNAD(+)-bin

31 f the chemokine receptor CCR5 and the C-type lectin receptor CD161, both implicated in regulating tis

32 y an 18-fold higher expression of the C-type lectin receptor CD209a, a murine homolog of human DC-spe

33 Here, we show that the C-type lectin receptor CD69 controls tTreg cell development and

34 CLEC-2 is a member of new family of C-type lectin receptors characterized by a cytosolic YXXL downs

35 The C-type lectin receptor CLEC-2 activates platelets through Src a

36 The C-type lectin receptor CLEC-2 signals through a pathway that is

37 during development by activating the C-type lectin receptor, CLEC-2, on platelets.

38 Here, we identified functions of one C-type lectin receptor, CLEC12A, in facilitating DC binding and

39 he genes most upregulated in pDC were C-type lectin receptor CLEC4E, IL-1Rs (IL-1R1 and -2), proinfla

40 We investigated the role of the C-type lectin receptor, CLEC5A, in macrophage activation and pu

41 Here, we have identified the C-type lectin receptor CLECSF8 (CLEC4D, MCL) as a key molecule

42 ycans that support recognition by the C-type lectin receptor (CLR) DC-specific intercellular adhesion

43 Members of the C-type lectin receptor (CLR) family stand out among the special

44 , trehalose dimycolate, activates the C-type lectin receptor (CLR) Mincle.

45 al infection stimulates the canonical C-type lectin receptor (CLR) signaling pathway via activation o

46 C-type lectin receptors (CLRs) are essential in shaping the imm

47 C-type lectin receptors (CLRs) comprise a heterogeneous group o

48 everal spleen tyrosine kinase-coupled C-type lectin receptors (CLRs) have emerged as important patter

49 owever, the role of TRAF6 and TAK1 in C-type lectin receptors (CLRs) in response to fungal infection

50 C-type lectin receptors (CLRs) represent a family of pattern re

51 C-type lectin receptors (CLRs) such as Dectin-2 function as pat

52 Dendritic-cell (DC)-associated C-type lectin receptors (CLRs) take up antigens to present to T

53 The innate pattern recognition C-type-lectin receptors (CLRs), including mannose receptor (MRC

54 attern recognition receptors, such as C-type lectin receptors (CLRs), on dendritic cells (DCs).

55 C-type lectin receptors (CLRs), the carbohydrate-recognizing mo

56 recognition receptors (PRRs) known as C-type lectin receptors (CLRs).

57 kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for invasion and persistence wit

58 (DCs), including cells expressing the C-type lectin receptor DC-SIGN, persisted at sites of HSV-2 rea

59 nt antibodies 2G12 and PGT123, or the C-type lectin receptor DC-SIGN.

60 g transfected cell lines, the type II C-type lectin receptor DC-specific ICAM-3-grabbing nonintegrin

61 ndritic cells (DCs) via targeting the C-type lectin receptor DC-specific intercellular adhesion molec

62 e, we found that the FcRgamma-coupled C-type lectin receptor DCAR (dendritic cell immunoactivating re

63 port intradermally injected mAbs against the lectin receptor DEC-205/CD205 in vivo.

64 d pulmonary dendritic cells express a C-type lectin receptor, DEC-205 (CD205), which mediates antigen

65 The C-type lectin receptor dectin-1 functions as a pattern recognit

66 tic cells (DCs) and macrophages via a C-type lectin receptor dectin-1 pathway.

67 The Syk-coupled C-type lectin receptor Dectin-1 was the first non-Toll like rec

68 The myeloid C-type lectin receptor Dectin-2 directs the generation of Th2 a

69 n (Mn), an Mn (sugar) polymer, by the C-type lectin receptor Dectin-2 on host macrophages leads to a

70 sonization but appears to require the C-type lectin receptor Dectin-3, a receptor not previously eval

71 we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially modula

72 Previously we identified the novel type II lectin receptor, dectin-1, that is expressed preferentia

73 Conversely, signaling via other C-type lectin receptors did not alter disease course.

74 mannose-dependent ligands for innate immune lectin receptors, disrupting the phylogenic basis of thi

75 toll-like receptors (TLRs) and fungal C-type lectin receptors (e.g., dectin-1).

76 molecule-3-grabbing nonintegrin) is a C-type lectin receptor expressed on macrophages and dendritic c

77 Previously, we identified dectin-2, a C-type lectin receptor expressed selectively by LC-like XS cell

78 ectin receptor with high homology to type II lectin receptors expressed by natural killer (NK) cells.

79 urthermore, common unique patterns of C-type lectin receptor expression were identified between these

80 ytes, macrophages, and DC; determined C-type lectin receptor expression; and tested the contribution

81 GR-1 is replaced by that of unrelated C-type lectin receptors fail to promote cross-presentation.

82 been the parallel discoveries in the C-type lectin receptor family and the Th effector arms of immun

83 known to interact with members of the C-type lectin receptor family of pattern recognition proteins,

84 Many members of the C-type lectin receptor family serve as pattern recognition rece

85 primarily mediated by members of the C-type lectin receptor family.

86 Dectin-1 is a lectin receptor for beta-glucan that is important for in

87 n profile of all KIR family genes and C-type lectin receptor genes using RNA sequencing on NKTCL case

88 More recently, ATVs targeted to C-type lectin receptors have been exploited for induction of po

89 PAR)-2, Toll-like receptor (TLR), and C-type lectin receptors have been suggested to be important for

90 singly high affinities toward Concanavalin A lectin receptor in comparison to their homomultivalent a

91 Increasingly, roles are emerging for C-type lectin receptors in immune regulation.

92 ike receptor, the characterization of C-type lectin receptors in innate immunity requires the identif

93 eptors, receptor tyrosine kinase, and C-type lectin receptors in the context of recent progress in th

94 s blockade of CD4 and mannose-binding C-type lectin receptors including dendritic cell-specific inter

95 In particular, C-type lectin receptors, including the mannose receptor (MR), f

96 Thus, targeting glycosylation-dependent lectin-receptor interactions may increase the efficacy o

97 CLEC9A is a recently discovered C-type lectin receptor involved in sensing necrotic cells.

98 ate recognition domain of Langerin, a C-type lectin receptor involved in the host defense against vir

99 ach is that structural information about the lectin/receptor is not required to obtain a multivalent

100 Here, we identify a lectin receptor kinase (LecRK), LecRK-I.8, as a potentia

101 not Respond to Nucleotides 1), defective in lectin receptor kinase I.9 (Arabidopsis Information Reso

102 demonstrate that the BABA-responsive L-type lectin receptor kinase-VI.2 (LecRK-VI.2) contributes to

103 evealed that a member of the A4 subfamily of lectin receptor kinases (LecRKs) of Arabidopsis (Arabido

104 human and murine forms of the myeloid C-type lectin receptor langerin for simple and complex ligands

105 ans cells (eLCs) uniquely express the C-type lectin receptor langerin in addition to the HIV entry re

106 al Langerhans cells (LCs) express the C-type lectin receptor langerin that functions as a pattern rec

107 This notably depends on the C-type lectin receptor, langerin or DC-SIGN, involved in gp120

108 utrophils elicited in the presence of C-type lectin receptor ligands have an increased ability to pro

109 Lectin receptor-like kinases (LecRLKs) are class of memb

110 Lectin receptor-like kinases (LecRLKs) are members of RL

111 Lectin receptor-like kinases (Lectin RLKs) are a large f

112 lose-6,6-dibehenate (TDB) bind to the C-type lectin receptors macrophage-inducible C-type lectin (Min

113 ual activation of newborn DCs via the C-type lectin receptor, macrophage-inducible C-type lectin (tre

114 damaged epithelium via expression of C-type lectin receptors, many of which signal through the Syk s

115 onintegrin (DC-SIGN), mannose binding C-type lectin receptors (MCLR), and heparan sulfate proteoglyca

116 f B cells binds gp120 through mannose C-type lectin receptors (MCLRs).

117 ewis(X) (Le(X)) re-directs OVA to the C-type lectin receptor MGL1.

118 previously uninvestigated role of the C-type lectin receptor Mincle in pneumonic sepsis caused by K.

119 alose dimycolate (cord factor) by the C-type lectin receptor mincle partially explains this CARD9 req

120 In rodents, the C-type lectin receptors Mincle and Mcl bind TDB/TDM and activat

121 r immunoglobulinlike receptor (KIR) and CD94 lectin receptor negative.

122 vely recognized by Mincle (Clec4e), a C-type lectin receptor of the innate immune system that is stro

123 accharide-coated beads, indicating selective lectin receptor/oligosaccharide interactions mediating c

124 responsible for this interaction involves a lectin receptor on the surface of the porcine Kupffer ce

125 have previously shown that different C-type lectin receptors on DCs play a major role in allergen re

126 tochastic activation of toll-like and c-type lectin receptors on macrophages causes neuroprotection o

127 Clec9a (C-type lectin receptor) or DNGR-1 (dendritic cell NK lectin gro

128 We sought to analyze C-type lectin receptor pathways as an alternative or a coactiva

129 C-type lectin receptors play important roles in immune cell int

130 functional engagement of an inhibitory host lectin receptor promotes bacterial innate immune evasion

131 ined the mechanism by which Mincle, a C-type lectin receptor, regulates NET formation.

132 n (cis infection), whereas binding to C-type lectin receptors results both in cis replication, as wel

133 rt, we demonstrate that expression of C-type lectin receptor scavenger receptor-AI (SR-AI) is crucial

134 C-type lectin receptors sense a diversity of endogenous and exo

135 Therein, the endocytic C-type lectin receptors serve as pattern recognition receptors,

136 ene expression, particularly of TLRs, C-type lectin receptors, several complement components, as well

137 CD33-related sialic acid binding Ig-like lectin receptors (Siglecs) have been implicated in the c

138 alic acid-binding immunoglobulin superfamily lectin receptors (Siglecs) provide negative regulation.

139 s residing in the lymph node medulla use the lectin receptor SIGN-R1 to capture lymph-borne influenza

140 illustrate the complexity of myeloid C-type lectin receptor signaling, and how an activating hemITAM

141 We propose that a C-type lectin receptor, SIGNR-1 (also called Cd209b), helps to

142 G2D reveals close homology with other C-type lectin receptors such as CD94, Ly49A, rat MBP-A and CD69

143 hway of ER quality control consists of a two-lectin receptor system consisting of Yos9p and Htm1/Mnl1

144 DNGR-1 is a C-type lectin receptor that binds F-actin exposed by dying cell

145 Dectin-1 (Clec7a) is a paradigmatic C-type lectin receptor that binds Syk through a hemITAM motif a

146 Mincle is a C-type lectin receptor that is critical in the immune response

147 Langerin is a C-type lectin receptor that recognizes glycosylated patterns on

148 occurs upon engagement of Dectin-1, a C-type lectin receptor that signals via spleen tyrosine kinase

149 ese findings place Dectin-2 among the C-type lectin receptors that activate arachidonic acid metaboli

150 ber of spleen tyrosine kinase-coupled C-type lectin receptors that have been implicated not just in f

151 rate that human NK cells also express C-type lectin receptors that influence recognition of polymorph

152 specific compartments is regulated by C-type lectin receptors that recognize glycan structures.

153 tly higher induction of CD23, a novel C-type lectin receptor, through NFATc1-mediated regulation of t

154 ed to DC surface receptors (including C-type lectin receptors, TLRs, and galectins).

155 us, CLEC9A functions as a SYK-coupled C-type lectin receptor to mediate sensing of necrosis by the pr

156 in DCs bound and internalized Env via C-type lectin receptors, whereas blood DC subsets, including CD

157 . albicans infection via signals from C-type lectin receptors, which signal through the adaptor CARD9

158 CLEC4M is a lectin receptor with a polymorphic extracellular neck re

159 DECTIN-1 is a type II lectin receptor with high homology to type II lectin rec