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1 the correlation of CF with impedance during left atrial 3-dimensional electroanatomical mapping and
2 ce of stroke occurred in those with baseline left atrial abnormality (incidence rate per 1,000 person
3 We found an association between ECG-defined left atrial abnormality and subsequent nonlacunar ischem
4 th nonlacunar stroke, given that we expected left atrial abnormality to reflect the risk of thromboem
5 d for potential confounders and incident AF, left atrial abnormality was associated with incident isc
7 V1 , an electrocardiographic (ECG) marker of left atrial abnormality, and incident ischemic stroke su
11 ngs add to the hypothesis that the posterior left atrial adipose tissue mass contributes to structura
14 ry disease), each gram increase of posterior left atrial adipose tissue was associated with 1.32 odds
17 Systems biology and multifeature profiles of left atrial anatomy and physiology should be used to ass
19 yzed according to 11 predefined areas in the left atrial and 6 segments around the ipsilateral pulmon
20 ESI >3.7 g/day was associated with larger left atrial and left ventricular dimensions (p < 0.05).
22 nificant improvement in AF symptoms, o2peak, left atrial and ventricular function, lipid levels, and
27 er the empirical electrical isolation of the left atrial appendage (LAA) could improve success at fol
29 the characterization of left atrial (LA) and left atrial appendage (LAA) flow dynamics in patients wi
35 with nonvalvular atrial fibrillation (NVAF), left atrial appendage (LAA) occlusion was noninferior to
37 l as premature atrial contractions, from the left atrial appendage at a coupling interval of 200 ms i
39 dy sought to assess composite data regarding left atrial appendage closure (LAAC) in 2 randomized tri
42 Atrial Fibrillation) trial demonstrated that left atrial appendage closure (LAAC) with the Watchman d
45 an updated overview of current transcatheter left atrial appendage closure devices and review the res
47 dverse outcomes associated with percutaneous left atrial appendage closure is higher in the real-worl
51 vices and review the results associated with left atrial appendage closure, focusing on procedural an
54 rm follow-up continues to support a role for left atrial appendage exclusion from the central circula
56 tting typically results from thrombus in the left atrial appendage has led to the development of mech
57 AF the intramyocardial blood vessels of the left atrial appendage have an increased CML presence and
58 significantly higher in blood vessels of the left atrial appendage in AF patients as compared to cont
59 mly assigned to undergo empirical electrical left atrial appendage isolation along with extensive abl
60 ng the effectiveness of empirical electrical left atrial appendage isolation for the treatment of LSP
62 ring repeat procedures, empirical electrical left atrial appendage isolation was performed in all pat
63 ups were novel oral anticoagulants, Watchman left atrial appendage occlusion device (DEVICE), and war
64 of stroke, site-specific therapy directed at left atrial appendage occlusion has been now studied for
67 ) of follow-up from the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in P
68 rawn predominantly from PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in P
71 ar) follow-up of Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Preven
72 tral annulus along the posterior base of the left atrial appendage visualized by selective angiograph
73 ctural parameters of the left atrium and the left atrial appendage which have been shown to be associ
82 itus had a greater left ventricular mass and left atrial area than patients without diabetes mellitus
83 c AF (66% paroxysmal AF; age, 58+/-10 years; left atrial area, 27+/-7 cm(2)) underwent preprocedure C
84 adjustments for left ventricular mass index, left atrial area, and interim heart failure events parti
86 ial LGE signal intensity divided by the mean left atrial blood pool intensity was calculated for each
87 s were analyzed using left ventricle cavity, left atrial cavity, or inferior vena cava as the IDIF.
88 We sought to examine the association between left atrial conduction velocity and LGE in patients with
90 -up of 976.5 days between patients with LAE (left atrial diameter > 45 mm; LAE group) and those witho
91 ber of AF episodes in the previous year, and left atrial diameter (adjusted hazard ratio, 0.35 [95% C
95 rdless of MS status, as evidenced by greater left atrial diameter and left ventricular mass although
96 ears; mean CHA2DS2-VASc score was 4.1+/-1.4; left atrial diameter averaged 4.7+/-0.8 cm; and 48% had
97 P=0.015) scores as well as persistent AF and left atrial diameter were significant predictors for ERA
98 confidence interval, 2.070-7.143; P<0.001), left atrial diameter>/=50 mm (hazard ratio 2.083; 95% co
99 nts (18 women; mean age, 61+/-11 years; mean left atrial diameter, 43+/-5 mm) with paroxysmal (36 of
101 ug use, previous use of diuretics, increased left atrial diameter, increased left ventricular end-dia
104 astolic, longitudinal systolic function, and left atrial dilatation compared with asymptomatic patien
106 , LV hypertrophy, concentric remodeling, and left atrial dilatation when corrected for indices of AS
109 PO in MT1-MMP reduced expression reduced left atrial dimension (19%), LTBP-1 hydrolysis (40%), an
110 ydrolysis (18%), collagen content (60%), and left atrial dimension (19%; indicative of LV diastolic d
111 o [HR] per decade, 1.55; 95% CI, 1.11-2.15), left atrial dimension (HR per centimeter diameter, 1.43;
112 wall thickness, LV diastolic dimension, and left atrial dimension (P<0.01 for all; n=2392; mean age,
113 had associated cardiovascular disease, mean left atrial dimension was 46+/-6 mm, and median CHA2DS2-
115 al pathophysiology), cause and effect (i.e., left atrial dynamics impute disease events as consequenc
117 s also exhibited a signi fi cant increase in left atrial ejection fraction at 2 months after gene del
118 Left ventricular adaptation was similar; left atrial ejection fraction improved by +3.17% (P < 0.
124 ive physiology, characterized by progressive left atrial enlargement and diastolic dysfunction with p
125 d age, female sex, greater right atrial than left atrial enlargement and lower systolic pulmonary art
127 traditionally have been used as markers for left atrial enlargement, and both have been associated w
128 alls, decreased left ventricular dimensions, left atrial enlargement, and hyperdynamic left ventricul
129 , including left ventricular hypertrophy and left atrial enlargement, in addition to pulmonary hypert
131 r hypercontractility, diastolic dysfunction, left-atrial enlargement and left ventricular fibrosis, a
134 sted overall hazard ratio per 1% increase in left atrial fibrosis was 1.06 (95% CI, 1.03-1.08; P < .0
135 ent, were predominantly found in the lateral left atrial free wall, and likely acted as drivers.
138 , elevated post-bypass Fontan (>20 mm Hg) or left atrial (>13 mm Hg) pressures, prolonged chest tube
139 sure was </=15 mm Hg in 54%, indicating that left atrial hypertension was absent in a majority of pat
142 ntricular (LV) dysfunction, ischemic MR, and left atrial infarction (LAI); and 2) to analyze how LA r
143 n FEV1/FVC ratio was associated with smaller left atrial internal dimension (beta = -0.038 cm per SD
144 luded pulmonary vein isolation in 50 (100%), left atrial isthmus line in 47 (94%), anterior line in 4
145 imaging was used for the characterization of left atrial (LA) and left atrial appendage (LAA) flow dy
149 ht to determine the prognostic importance of left atrial (LA) dilation in patients with type 2 diabet
152 agnetic resonance (CMR) signal intensity and left atrial (LA) endocardial voltage after LA ablation.
153 oncentric left ventricular (LV) hypertrophy, left atrial (LA) enlargement and dysfunction, and LV dia
171 sought to (1) identify reference values for left atrial (LA) volumes and phasic function indices by
172 inium enhancement MRI (LGE-MRI) can identify left atrial (LA) wall structural remodeling (SRM) and st
173 Prior studies have demonstrated regional left atrial late gadolinium enhancement (LGE) heterogene
178 ickness and image intensity ratio defined as left atrial myocardial LGE signal intensity divided by t
181 clinical in vivo study, we demonstrate that left atrial myocardium with increased gadolinium uptake
182 In vitro I-1c gene transfer in isolated left atrial myocytes from both pigs and rats increased c
186 l voltage amplitude (right atrial, P=0.0005; left atrial, P=0.0001), slower conduction velocities (ri
187 conduction velocities (right atrial, P=0.02; left atrial, P=0.0002), and higher prevalence of electro
188 tudy was to test the hypothesis that reduced left atrial passive emptying function (LAPEF) as determi
189 clustering (i.e., commonality of underlying left atrial pathophysiology), cause and effect (i.e., le
191 th was delivered to the left atrium, and the left atrial port was closed using an off-the-shelf nitin
192 e relationship between the esophagus and the left atrial posterior wall is variable, and the esophagu
193 +/- 44 mm Hg to 12 +/- 6 mm Hg; p = 0.007), left atrial pressure (29 +/- 11 mm Hg to 20 +/- 8 mm Hg;
194 systemic hypotension occurred with a fall in left atrial pressure and little change in left ventricul
195 evice is feasible, seems to be safe, reduces left atrial pressure during exercise, and could be a new
197 rt failure, interventions to reduce elevated left atrial pressure improve symptoms and reduce the ris
198 nd we describe the design of REDUCE Elevated Left Atrial Pressure in Heart Failure (REDUCE LAP-HF I),
204 nt device that allows shunting to reduce the left atrial pressure provides clinical and hemodynamic b
205 EF is complex but characterised by increased left atrial pressure, especially during exertion, which
207 a heterogeneous clinical syndrome, elevated left atrial pressure-either at rest or with exertion-is
209 reath-hold to the atrioventricular junction, left atrial pulmonary vein junction, and freewall left v
212 sus -6.5 [-46.2 to 28.9] degrees C, P<0.001; left atrial-PV junction: -6.7 [-20.0 to 21.4] versus 15.
213 procedural rivaroxaban administration during left atrial radiofrequency ablation (RFA) in comparison
216 ents (mean age, 63+/-10 years) who underwent left atrial RFA procedures between February 2012 and May
220 ventricular ejection fraction (P = 0.67), or left atrial size (P = 0.43) after SAVR on echocardiograp
222 he author reviews the methods used to assess left atrial size and function and discusses their role i
224 g clinical predictors with the evaluation of left atrial size by echocardiography serving as the sole
225 and 10 cm/s, respectively), whereas E/e' and left atrial size demonstrated good agreement with guidel
226 N-terminal pro-brain natriuretic peptide and left atrial size suggest that the angiotensin receptor n
227 ptide levels, C-reactive protein levels, and left atrial size were associated with arrhythmia recurre
228 (tissue Doppler imaging [TDI] e', E/e', and left atrial size) with concomitant N-terminal pro-brain
229 alysis, only RV fractional area change, age, left atrial size, diabetes, and previous coronary artery
230 mated glomerular filtration rate, and larger left atrial size, left ventricular volume, and mass.
231 imary outcome after correction for age, sex, left atrial size, nonsustained ventricular tachycardia,
237 s (namely segmental left ventricular strain, left atrial strain, and right ventricular strain) are al
243 Basket electrodes were within 1 cm of 54% of left atrial surface area, and a mean of 31 electrodes pe
245 t an underlying atrial cardiopathy may cause left atrial thromboembolism in the absence of recognized
246 rs of stroke, CHADS2 score and CHA2DS2-Vasc, left atrial thrombus (LAT), the five-grades of LASEC and
248 lude axial flow pumps, such as Impella((R)); left atrial to femoral artery bypass pumps, specifically
251 s a disease of variable interactions between left atrial triggers and substrate most commonly of left
252 [apnea-hypopnea index <5]), right atrial and left atrial voltage distribution, conduction velocities,
254 astolic dysfunction (P = .003) and increased left atrial volume (57 +/- 11 vs 46 +/- 12 mL/m(2), P =
258 Global ECV significantly correlated with left atrial volume (P = .002) and with the grade of dias
260 tion rate was higher (51.9%/y) in those with left atrial volume above the median value of 73.5 mL.
263 ta are sufficient to recommend evaluation of left atrial volume in certain populations, and although
264 elocities >2, RAP >10 mm Hg, sPAP >40 mm Hg, left atrial volume index >33 ml/m(2), ratio of mitral in
266 versus 268+/-62 ms; P<0.0001), and increased left atrial volume index (49+/-18 versus 42+/-15 mL/m2;
267 ricular global longitudinal strain (GLS) and left atrial volume index (LAVI) have been recently propo
268 interval, 1.04-1.43; P=0.015) and increased left atrial volume index (LAVi; adjusted hazard ratio/un
269 end-systolic volume index (r=0.62, P<0.01), left atrial volume index (r=0.41, P<0.05) but lower left
270 ing mitral inflow velocities, RAP, sPAP, and left atrial volume index was 90% accurate in distinguish
271 ft ventricular end-systolic volume index and left atrial volume index were independent predictors of
272 d diastolic function (based on e', E/e', and left atrial volume index) were each independently and ad
273 sis, LV mass index, relative wall thickness, left atrial volume index, and deceleration time were sti
274 rate, older age, elevated creatinine, larger left atrial volume index, and larger left ventricular en
275 e, including carotid intima-media thickness, left atrial volume index, monocyte count and serum YKL-4
277 with greater left ventricular (LV) mass and left atrial volume indexed to height(2.7) in both men an
278 nal pro B-type natriuretic peptide; however, left atrial volume reduction varied by baseline level of
280 sue inhibitor of matrix metalloproteinase 1, left atrial volume), myocardial stretch (NT-proBNP [N-te
281 (medial E/e', 16; deceleration time, 185 ms; left atrial volume, 44 mL/m(2)) and increased arterial l
282 V end-systolic volume, LV ejection fraction, left atrial volume, and LV dyssynchrony at 1-year in CRT
284 analysis identified age, diabetes mellitus, left atrial volume, and mean gradient as independent pre
285 s, mass, maximal wall thickness, morphology, left atrial volume, and mitral valve leaflet lengths (al
286 ection fraction, relative wall thickness and left atrial volume, and worse New York Heart Association
287 sed left ventricular end-diastolic pressure, left atrial volume, N-terminal propeptide of brain natri
293 1 +/- 36 ml to 122 +/- 30 ml; p < 0.001) and left atrial volumes (106 +/- 36 ml to 69 +/- 24 ml; p <
294 systolic circumferential strain (PSCS), and left atrial volumes and function, whereas phosphorus-31
295 ventricular (LV) systolic function, LV mass, left atrial volumes, and blood pressure response did not
298 sis, clustered by patient, and adjusting for left atrial wall thickness, conduction velocity was asso
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