ライフサイエンスコーパス: left-handed

1 age, 65 [54-81] years; 3 of 9 male [33%]; 0 left-handed).

2 reclassified into 2 groups: right-handed and left-handed.

3 They were less likely to smoke or to be left-handed.

4 on these peptides in chloroform indicated a left-handed 10/12-helix, while the CD spectrum in methan

5 mixture of polyproline II (PPII) and a novel left-handed 2.5(1)-helical conformation, which is an ext

6 74 [67-76] years; 1 of 5 male [20%]; 1 of 5 left-handed [20%]; and nfvPPA-CBD group: mean [IQR] age,

7 b predominantly sampled the right-handed and left-handed 3(10)-helix region and to a minor extent the

8 ity inversion of poly(BBPFA) proceeds from a left-handed 31 helix via multistate free energy pathways

9 ation is predicted to be almost a contracted left-handed 4-fold helix; i.e. similar to that observed

10 cal forms, right-handed all-cis (Form I) and left-handed all-trans (Form II), were determined in the

11 c carboxy termini are uniquely arranged in a left-handed alpha-helical bundle, directly interacting w

12 Non-Gly residues located near the left-handed alpha-helical region (L-alpha) of the Ramach

13 s for interacting with a molecular target, a left-handed alpha-helix.

14 to adopt compact right-handed (alpha(R)) and left-handed (alpha(L)) helical conformations.

15 some achiral and chiral substituents such as left-handed amino acids have been used.

16 Strikingly, the twisting is always left-handed and is not due to underlying cytoskeletal sk

17 a cubane iron-sulfur cluster indicates both left-handed and right-handed folds could exist and have

18 i is by the propagation of kinks, separating left-handed and right-handed helical waves.

19 we design a protein complex containing both left-handed and right-handed helices, with peptides of D

20 cus depth is significantly different between left-handed and right-handed individuals as determined b

21 a protein chain where the N-terminal half is left-handed and the C-terminal half right-handedly folde

22 are antiparallel, the global architecture is left-handed and the two component DNA strands are orient

23 ree broad categories namely "right-handed", "left-handed", and "M-shape".

24 patients were right handed, nine (15%) were left handed, and six (10%) had indeterminate hand domina

25 ctions in the DNA origami structures adopt a left-handed antiparallel conformation.

26 trast, soluble beta-helices, both right- and left-handed, are usually "capped" on each end by one or

27 han normal and exhibited a counterclockwise (left-handed) axial rotation bias.

28 Both right- and left-handed batters performed better in years dominated

29 emonstrate that this metamaterial exhibits a left-handed behaviour, and we directly observe the Chere

30 d a shared second domain predicted to form a left-handed beta helix are all critical for interprotein

31 extensive interactions between the PLDs and left-handed beta helix domains that form the eIF2Bgammae

32 ver, poor sequence homology between PglD and left-handed beta helix enzymes with existing structural

33 analysis predicts PglD to be a member of the left-handed beta helix family of enzymes.

34 equence of PrP is compatible with a parallel left-handed beta-helical fold.

35 Moreover, the parallel left-handed beta-helical model for PrP(Sc) may provide i

36 Our parallel left-handed beta-helical model provides a coherent frame

37 imeric or hexameric arrangement of right- or left-handed beta-helical models.

38 Left-handed beta-helices readily form trimers, providing

39 nstruct nanotubes using building blocks from left-handed beta-helices which are commonly occurring re

40 The left-handed beta-helix (LHBH) is an intriguing, rare str

41 This revealed an unusual left-handed beta-helix domain, with the phosphorylation

42 cterial acetyltransferase is a member of the left-handed beta-helix family and forms a homotrimer as

43 nit of the trimeric enzyme is dominated by a left-handed beta-helix motif with 11 turns.

44 erB, an N-acetyltransferase belonging to the left-handed beta-helix superfamily of proteins.

45 The C-terminal domain consists of a left-handed beta-helix, which has nearly seven turns.

46 beta-strands, 23 of which form the canonical left-handed beta-helix.

47 t these fibrils are composed of conventional left-handed beta-sheets, but that packing stresses betwe

48 l enantiomeric excess (EE) between right and left-handed biomolecules.

49 phenotype in POMT mutant embryos that shows left-handed body torsion.

50 The enzyme relaxes positive supercoils and left-handed braids 20 times faster, and with greater pro

51 Electrostatic stabilization of left-handed braids may stand behind the chiral selectivi

52 The filaments formed with ATP are left-handed, but surprisingly these filaments exert no t

53 propyzamide, which normally causes enhanced left-handed CFR and right skewing.

54 Twenty-seven left-handed children (17 boys, 10 girls) and 54 age- and

55 dence of atypical language lateralization in left-handed children in this study was similar to that r

56 values for the temporo-parietal ROI for the left-handed children were 18 (67%) left-dominant, 6 (22%

57 Until some decades ago, left-handed children who attended German schools were fo

58 and splenium) and for overall CC size, with left-handed chimpanzees exhibiting significantly smaller

59 In particular, for a left-handed chiral tip, transverse forces are attractive

60 Electron tomography revealed a left-handed chirality in the spiral tubes, double-wall t

61 Here, we demonstrate that left-handed chirality of the MreB cytoskeleton in the ro

62 Some of these tubes spontaneously form with left-handed chirality.

63 and TM (transverse magnetic) as well as LCP (left-handed circular polarization) and RCP (right-handed

64 dispersions of racemic CdTe NPs with right- (left-)handed circularly polarized light (CPL) induces th

65 were examined by five right-handed and five left-handed clinicians.

66 ed by L-enantiomers of Asp and Glu, whereas 'left-handed' (clockwise) morphology is induced by D-enan

67 tral standing dimer and form both right- and left-handed clusters on a conducting substrate.

68 The structure presented forms a left-handed coiled coil with an average helix tilt of 13

69 e NMR structure of the zetazeta(TM) dimer, a left-handed coiled coil with substantial polar contacts.

70 y that these proteins can adopt conventional left-handed coiled coils.

71 with the transmembrane domains arranged in a left-handed coiled-coil configuration, crossing the bila

72 . coli subunit b-dimer can stably exist as a left-handed coiled-coil.

73 ide chains, like those found in conventional left-handed coiled-coils, and this packing governs the c

74 t the proteins all are capable of packing as left-handed coiled-coils.

75 E. coli ATP synthase could pack into stable left-handed coiled-coils.

76 s follows a heptad repeat pattern typical of left-handed coiled-coils.

77 er than the expected +20 degrees for typical left-handed coiled-coils.

78 tructural models, including right-handed and left-handed coiled-coils.

79 enantiopure CTVs and mixtures of right- and left-handed columns from racemic by mixture, racemic by

80 encies and pave the way towards magnetic and left-handed components for visible optics.

81 We demonstrate that the bound DNA is in the left-handed conformation and identify key interactions f

82 ference of H3/H4 to form negative coils (the left-handed conformation).

83 14-Cys 38 disulfide bond between right- and left-handed conformations.

84 the N-terminus preferentially stabilized the left-handed conformer (DNA negatively supercoiled), and

85 These domains recognize the left-handed conformer of dsDNA and dsRNA known as Z-DNA/

86 d a mixed effect, i.e., when at serines, the left-handed conformer, and at threonines, a mixture of b

87 Variant H3.3 promoted only the left-handed conformer, and H3.1 tended to maintain both

88 ree molecular entities: the right-handed and left-handed conformers and a nonhelical domain.

89 tructure features such as split beta-sheets, left-handed connections, and crossing loops.

90 are Gly, Ala, and Ser, and that helices with left-handed crossing angles are more tightly packed on a

91 rfaces of helices that have either right- or left-handed crossing angles, and either parallel or anti

92 rientations and with similar right-handed or left-handed crossing angles.

93 were distorted relative to the WT and showed left-handed crossing of their helices.

94 due to its geometrical preference to act on left-handed crossings, Topo IV can specifically unknot s

95 freshly replicated sister DNA molecules form left-handed crossings.

96 ransition from a parallel TM helix pair to a left-handed crossover arrangement.

97 ed by the topological challenge of forming a left-handed crossover connection between beta-strands S2

98 central beta-sheet and alpha-helix C in the left-handed crossover connection between beta-strands tw

99 crossovers by groove-backbone interaction or left-handed crossovers by groove-groove juxtaposition.

100 Surprisingly, left-handed crossovers, assembled by sequence-independen

101 otably, molecular dynamics revealed that the left-handed dimer gets tilted en bloc, whereas conformat

102 for subunit b can be accommodated by classic left-handed, dimeric coiled-coil quaternary structures.

103 tablished heptad-repeat packing exhibited by left-handed, dimeric coiled-coils by employing simulated

104 d DNA helix is translocated and rotated in a left-handed direction.

105 ting subunits, and 2- to 5-fold enhanced for left-handed distal subunits.

106 lfide orientation and 5 exhibiting an "R" or left-handed disulfide orientation.

107 Interest to the left-handed DNA conformation has been recently boosted b

108 R solution and X-ray crystal structures of a left-handed DNA G-quadruplex.

109 The left-handed DNA structure, Z-DNA, is believed to play im

110 nucleosomes are octameric with conventional left-handed DNA wrapping, in contrast to other recent pr

111 dard histone H3-containing nucleosome with a left-handed DNA writhe at a nonfunctional STB.

112 [Co(NH(3))(6)](3+), (dm(5)C-dG)(4) assumes a left-handed double helical structure (Z-DNA), whereas th

113 olves formation of a bipolar spindle made of left-handed double-helical actin-like ParM filaments.

114 have high potential to form the nonclassical left-handed double-helical Z-DNA structure.

115 step, a clear preference of R-BINAS for the left-handed enantiomer of Au(38)(2-PET)(24) is observed

116 In the left-handed epilepsy population, there was high posttest

117 icantly different mean PD between right- and left-handed examiners (unadjusted P<0.05; differences at

118 in the measurement of PDs between right- and left-handed examiners at various locations in the mouth

119 easurements were compared between right- and left-handed examiners using analysis of variance (ANOVA)

120 record slightly higher PD measurements than left-handed examiners, but this difference did not reach

121 acid residues existed in a solvent-exposed, left-handed extended helical or poly (L-proline)-type (P

122 xtended conformational states: unordered and left-handed extended helical or poly (L-proline)-type II

123 Here, we report an unusually wide left-handed filament structure for an archaeal MCM, as d

124 four-helix bundle, and a pentameric parallel left-handed five-helix bundle.

125 Both right- and left-handed forms crystallized in the trigonal space gro

126 s the comparison with the rare but important left-handed forms.

127 ix 3 (PAH3) domain in the complex adopts the left-handed four-helix bundle structure characteristic o

128 residues of Zuo1 fold into an autoinhibitory left-handed four-helix bundle.

129 the disease-related human lysozyme, can form left-handed giant ribbons, closing into nanotubes.

130 These results also suggest that a left-handed Gly heptad repeat motif can drive membrane h

131 Left-handed gold nanoparticle double helices were prepar

132 nd simultaneously direct their assembly into left-handed gold nanoparticle double helices.

133 Based on the frontal ROI, in the left-handed group, 23 participants (85%) demonstrated le

134 rhm1 mutant roots also display left-handed growth.

135 lidated closed alpha-solenoid repeats with a left-handed helical architecture that--to our knowledge-

136 interactions in a fashion characteristic of left-handed helical coiled coils.

137 Although the left-handed helical conformation is not favorable for th

138 ibit a right-handed helical C terminus and a left-handed helical conformation toward the N-terminus,

139 selectivity filter, Gly-77 in KcsA, is in a left-handed helical conformation.

140 d-state NMR and found that it forms a stable left-handed helical dimer.

141 opic studies showed that ICP8 will form long left-handed helical filaments.

142 as right and noncoronary fusion gave rise to left-handed helical flow with left-posterior flow jets (

143 HAMNOSE BIOSYNTHESIS 1 (RHM1) cause dramatic left-handed helical growth of petal epidermal cells, lea

144 structural elements are consistent with two left-handed helical models: 2 residues/turn (2(4) helix)

145 n (DD) complex, which surprisingly reveals a left-handed helical oligomer that consists of 6 MyD88, 4

146 membrane-soluble peptides with a Gly-based, left-handed helical packing motif would associate.

147 ional units is found to form both right- and left-handed helical structures.

148 crystal lattice, 2a further assembles into a left-handed helical superstructure aligned along the cry

149 e resulting family of structures exhibited a left-handed helical twist, in agreement with the twisted

150 s of polyproline II, beta-strand, right- and left-handed helical, and gamma-turn-like conformations.

151 f regular secondary structure are preferred: left-handed helices with cis-peptide bonds and right-han

152 s than are currently recognized in right- or left-handed helices, spirals, and in antidistorted struc

153 e show that each virion contains two nested, left-handed helices: an outer helix of matrix protein M

154 configurations of which are denoted Lambda (left handed helix) or Delta (right handed helix).

155 in, harbors nucleic acid-binding domains for left-handed helix (Z-form) and receptor-interacting prot

156 de, amylose crystallizes as a regular single left-handed helix from a propanol, butanol, or iodine so

157 ight-handed helix in the subendocardium to a left-handed helix in the subepicardium.

158 rboxylate positions along the reported G2(+) left-handed helix of alpha-(2,8)-polysialic acid.

159 nvestigated homopeptides in that it adopts a left-handed helix which at acid pD is in part stabilized

160 The NC within the virion forms a left-handed helix with an inner nucleoprotein layer deco

161 in omega2 binds to parS DNA, forming a short left-handed helix wrapped around the full parS, and inte

162 The axes are coiled around each other as a left-handed helix, and AFD1 showed a bilaterally symmetr

163 corresponding oligo adopts a right-handed or left-handed helix, or a nonhelical motif.

164 odel were predicted to polymerize Bicc1 in a left-handed helix.

165 n which flagellin monomers are arranged in a left-handed helix.

166 ce suggested that polycytidylic acid forms a left-handed helix.

167 rongly argues in favour of the presence of a left-handed hetero-oligomer with an orientation compatib

168 o have reduced visuomotor skills relative to left-handed hitters.

169 lical DNA can be modeled to wrap around this left-handed HUalphabeta multimer.

170 his advantage of the left arm disappeared in left-handed human participants.

171 ) and common marmosets (Callithrix jacchus), left-handed individuals are less likely than right-hande

172 "Converted" left-handers are innately left-handed individuals forced as children to write with

173 Left-handed individuals have a deeper central sulcus in

174 An independent sample of right- and left-handed individuals showed that hand dominance affec

175 which can be either right-handed (Delta) or left-handed (Lambda).

176 ts, twist the ligand's pyridine rings into a left-handed (M) propeller (circular dichroism spectrosco

177 At large positive fields, both right- and left-handed magnon and two-magnon-like excitations are o

178 Although H3 nucleosomes wrap DNA in a left-handed manner and induce negative supercoils, we sh

179 In accordance with these hypotheses, left-handed marmosets were slower to explore novel foods

180 He proposed that a flat slab of left-handed material possessing an isotropic refractive

181 e direction of moving charged particles in a left-handed material.

182 Left-handed materials do not occur naturally, and it has

183 ue to the absence of both suitable all-metal left-handed materials for beam transport and suitable co

184 Left-handed materials require negative permeability micr

185 on a new class of smart materials--so-called left-handed media--that exhibit highly unusual electroma

186 gnetic polarization responses would yield a 'left-handed' medium in which light propagates with oppos

187 previously that electromagnetic waves inside left-handed metamaterials produce negative radiation pre

188 the Earth's prebiotic organic inventory with left-handed molecules before the origin of life.

189 NA are wrapped around the core histones in a left-handed, negative superhelix.

190 In the left-handed nonepileptic subjects, there was high postte

191 a, which appears to lack the ability to bind left-handed nucleic acids.

192 are inconsistent with in vitro evidence for left-handed octameric CenH3 nucleosomes.

193 omes that display properties consistent with left-handed octamers.

194 ely 90%) preferred right-handed helices over left-handed ones, with a helix radius of approximately 0

195 bsence of ATP, MCM2-7 spontaneously adopts a left-handed, open-ring structure.

196 exists on whether subunit b adopts a classic left-handed or a presumed right-handed dimeric coiled-co

197 ules with a significant excess of either the left-handed or right-handed enantiomer.

198 eraction can be adjusted to stabilize either left-handed or right-handed Neel walls, or non-chiral Bl

199 Snail shells can be left-handed or right-handed, sometimes within one specie

200 bers, consists of an antiparallel motif with left-handed packing angles, and it is frequently stabili

201 The two transmembrane helices form a left-handed packing arrangement with a crossing angle of

202 mann fold and the C-terminal domain adopts a left-handed parallel beta helix that is involved in coop

203 75 kDa hexamer displaying the characteristic left-handed parallel beta-helix (LbetaH) structural doma

204 s of an N-terminal uridine-binding region, a left-handed parallel beta-helix (LbetaH), and a C-termin

205 cts, revealed that LpxA contains an unusual, left-handed parallel beta-helix fold.

206 ors, revealed that LpxA contains an unusual, left-handed parallel beta-helix fold.

207 ) to GlcNAc-1-PO(4) and displays the longest left-handed parallel beta-helix observed to date.

208 n the near zero-index passband, or the right/left-handed passband.

209 ortantly, this tendency was also seen in the left-handed patients, while it was not statistically sig

210 sue and separately analyzed right-handed and left-handed patients.

211 icult to separately analyze right-handed and left-handed patients.

212 we numerically examine optical forces inside left-handed photonic crystals demonstrating negative ref

213 isted, ribbon-like, helical filaments with a left-handed pitch and protomer nucleotide binding pocket

214 tetrameric state, the H3-H3 interface has a left-handed pitch prior to binding DNA.

215 a relatively long (approximately 1 microm), left-handed pitch that is insensitive to myosin concentr

216 the predictions of this hypothesis, however, left-handed pitchers were more successful when they were

217 Our findings reveal a novel source of left-handed plant growth caused by changes in cell wall

218 s have a significant propensity to adopt the left-handed polyproline II (P(II)) helical conformation.

219 demonstrate that urea promotes formation of left-handed polyproline II (P(II)) helical structures in

220 The left-handed polyproline II (P(II)) helix is a structure

221 The collagen triplex is made of three left-handed polyproline II (PPII) helices with each PPII

222 that (phi, psi) values corresponding to the left-handed polyproline II helix (P(II)) are preferred f

223 re reveals the presence of a surface-exposed left-handed polyproline II helix that is closely packed

224 ses a right-handed bundle of three parallel, left-handed polyproline II-type helices.

225 ndicate this small fusion module comprises a left-handed polyproline type II (PPII) helix flanked by

226 ' and the following loop up to the distorted left-handed PP(II) helix, is located at a unique positio

227 fAFP molecule is made up of six antiparallel left-handed PPII helixes, stacked in two sets of three,

228 The ribonucleocapsids were left-handed, randomly oriented, and curved inside the vi

229 Left-handed residents had fewer complications compared w

230 smonic waveguides, yields an omnidirectional left-handed response for transverse magnetic polarizatio

231 Scaling the left-handed response to higher frequencies, such as infr

232 implementation of a bulk metamaterial with a left-handed response to ultraviolet light.

233 s only recently become possible to achieve a left-handed response using metamaterials, that is, elect

234 e fabrication of resonant metamaterials with left-handed responses at frequencies beyond the visible.

235 So far, left-handed responses have typically been implemented us

236 p in d(pGpG) results in stabilization of one left-handed Rh(2)(OAc)(2) [d(pGpG)] HH1 L conformer, due

237 4 tasks, and chimpanzees were classified as left-handed, right-handed, or ambidextrous.

238 attached histidine kinase domains undergo a left handed rotation within microseconds.

239 ationary at FASs, the motor complex powers a left-handed rotation of the cell around its long axis.

240 f the structures forms spiral filaments with left-handed rotations.

241 id body rather than the proposed 140 degrees left-handed screw motion.

242 s at the N-terminus of the oligomer induce a left-handed screw sense, while quaternary L-amino acids

243 ses from energetic determinants (adoption of left-handed single-residue conformations by Gly 68, and

244 The structure consists of a left-handed, six-stranded beta-barrel capped at one end

245 d molecular dynamics predict a tightly wound left-handed solenoid fold in which the cysteines form a

246 antea and on the left side in the sinistral (left-handed) species Biomphalaria glabrata.

247 These show that Cdt1 stabilizes MCM in a left-handed spiral open at the Mcm2-5 gate.

248 id residue critical for the formation of the left-handed spiral protein in the crystal was defective

249 d) reported herein, T-ag obd monomers form a left-handed spiral with an inner channel of 30 angstroms

250 protomers") further assemble into a low-rise left-handed staircase.

251 ate termed "P-RNA," and a highly underwound, left-handed state denoted "L-RNA." Beyond these similari

252 he right-handed bundle is in contrast to the left-handed structures obtained in previous modelling ef

253 -coil and their carboxy termini arrayed in a left-handed super-helical coiled-coil.

254 opies of the Cse4 protein and wraps DNA in a left-handed supercoil, similar to the canonical H3 nucle

255 ability of a sequence to assume the required left-handed superhelical conformation.

256 r resist uptake in nucleosomes along various left-handed superhelical pathways and to deduce the feat

257 ded DNA is tightly packed in the capsid as a left-handed superhelix and held in place by the interact

258 cognizes the chiral crossings imposed by the left-handed superhelix of a (+) supercoiled DNA, rather

259 octameric nucleosomes that organize DNA in a left-handed superhelix.

260 , the molecule multimerizes in the form of a left-handed superhelix.

261 f neighboring TPR proteins generates a novel left-handed suprahelical TPR assembly.

262 duces a right-handed helix that enriches the left-handed SWNTs for all suspended (n,m) species.

263 burn", causes diameter dilation of only the left-handed SWNTs, whose improved intermolecular interac

264 A 28yo semi-professional left handed tennis player was complaining about pain in

265 Only a left-handed tetrameric model was compatible with the exp

266 s more balanced (e.g., 67% right-handed, 33% left-handed), these cognitive representations are less e

267 solutions reveal distinguishing features for left-handed three-residue per turn PPII helices: the lac

268 Both structures are left-handed three-stranded helical filaments, revealing

269 cal twist sense changes from right-handed to left-handed through an achiral liquid-crystal phase, whe

270 The 20 lowest-energy structures show a left-handed tilt of TM3 relative to TM2 with a tilting a

271 This left-handed TM2-TM3 arrangement ensures a neatly packed

272 a moving discontinuity in a composite right/left-handed transmission line loaded with varactors when

273 We report the stereoselective synthesis of a left-handed trefoil knot from a tris(2,6-pyridinedicarbo

274 unusually consists of an extended, rod-like left-handed trimeric coiled-coil.

275 ich is at variance with the earlier reported left-handed turn structure.

276 A2 filaments with 4.4 dimers per 120 A pitch left-handed turn.

277 around which DNA wraps tightly in almost two left-handed turns.

278 olved long central domain with 90 degrees of left-handed twist and near 2-fold symmetry.

279 Most of the CC structure has a left-handed twist with heptad repeats, but both coil 1B

280 monomer, the two screw-like pathways have a left-handed twist, undergoing a counter-clockwise rotati

281 ion indicates that normal VCD fibrils have a left-handed twist, whereas reversed VCD fibrils are flat

282 a helical pitch of approximately 410 A and a left-handed twist.

283 light (CPL) induces the formation of right- (left-)handed twisted nanoribbons with an enantiomeric ex

284 tinuum electrostatics reproduce the distinct left-handed twisted ion pathways for K(+) and Cl(-) exte

285 growth of petal epidermal cells, leading to left-handed twisted petals.

286 f WVD2-overexpressing rosette leaves exhibit left-handed twisting.

287 Each repeat forms a left-handed, two-helix bundle that presents an RVD-conta

288 nus: the tertiary amino acid L-Val induces a left-handed type II beta-turn in both the solid state an

289 Ent-DDI is a left-handed wedge-shaped spirocyclic molecule whose agly

290 an colony-stimulating factor 1 gene into the left-handed Z-conformation.

291 Since its discovery in 1979, left-handed Z-DNA has evolved from an in vitro curiosity

292 s in solution, (ii) the self-organization of left-handed Z-DNA with alternating [dC-dG] sequences in

293 res, such as the four-stranded G-quadruplex, left-handed Z-DNA, cruciform and others.

294 a transition between right-handed B-form and left-handed Z-form DNA under controlled supercoiling.

295 The sequence crystallizes as a left-handed Z-form double helix with Watson-Crick base p

296 similar to those of the naturally occurring left-handed Z-form of DNA.

297 sion of multiple regions of genomic DNA into left-handed Z-form.

298 same duplex DNA between right-handed B- and left-handed Z-forms leads to a diode-like switch in spin

299 two alternative configurations, including a left-handed Z-RNA conformation and a compact purine Trip

300 NA conformation and a destabilization of the left-handed Z-RNA.