ライフサイエンスコーパス: left-right axis

1 of nervous systems are asymmetric about the left-right axis.

2 ymmetry in nodal family signaling across the left-right axis.

3 eral somite formation is regulated along the left-right axis.

4 e plays a key role in establishing the avian left-right axis.

5 rn correlates with normal development of the left-right axis.

6 gastrulation for proper establishment of the left-right axis.

7 hat mature GDF1 is sufficient to reverse the left-right axis.

8 terning events that establish the vertebrate left-right axis.

9 ms that allow embryos to reliably orient the left-right axis.

10 eages and birth positions with regard to the left-right axis.

11 o is initially broken to define a consistent left-right axis.

12 d AVSDs only concurrently with heterotaxy, a left/right axis abnormality.

13 LIC is required for the establishment of the left-right axis and for normal expression of Nodal, and

14 tinoic-acid signalling is uniform across the left-right axis and occurs in node ectoderm but not node

15 rically, neurons must be specified along the left-right axis, assigned left-side versus right-side id

16 ared co-receptor Cryptic to specify visceral left-right axis asymmetry.

17 xes, it is symmetrically expressed along the left-right axis at early stages of embryonic and cardiac

18 own to be asymmetrically expressed along the left-right axis before the development of organ asymmetr

19 manipulations in any vertebrate by which the left-right axis can be reliably controlled.

20 d homeobox gene, plays a crucial role in the left-right axis determination and dextral looping of the

21 ctivation of KIF3A produces abnormalities of left-right axis determination and embryonic lethality.

22 rate that Pitx2c plays a crucial role in the left-right axis determination and rightward heart loopin

23 l patterning of the spinal cord, a defect in left-right axis determination and severe polydactyly (ex

24 Dyneins have been implicated in left-right axis determination during embryonic developme

25 When errors in left-right axis determination happen, they almost always

26 nge of biological responses, from control of left-right axis determination in embryonic development t

27 ese genes was not associated with defects in left-right axis determination in humans or zebrafish.

28 f8 and Sonic Hedgehog genes are required for left-right axis determination in the mouse embryo, but t

29 imately govern gut formation and patterning, left-right axis determination, and development of the ce

30 ardiac development and upstream processes of left-right axis determination, and to consider how pertu

31 Furthermore, left-right axis determination, neural induction and somi

32 ole in several mammalian processes including left-right axis determination, sperm motility, and photo

33 PHP to PKD, to primary cilia function and to left-right axis determination.

34 Pitx2 also has a postulated role in left-right axis determination.

35 nr-1 expression per se is a causal factor in left-right axis determination.

36 ermore, PCSK6 is a protease that cleaves the left-right axis determining protein NODAL.

37 te genes have emerged from recent studies of left-right axis development in chick, frog and mouse, wh

38 genes required for the establishment of the left-right axis during early development.

39 Specification of the left-right axis during embryonic development is critical

40 node have been implicated in initiating the left-right axis during embryonic development, but how ci

41 ole of EGF-CFC genes and Nodal signalling in left-right axis formation is conserved from fish to huma

42 Defects in embryonic left-right axis formation represent a significant portio

43 e exhibited a spectrum of defects related to left-right axis formation, including visceral situs inve

44 al roles in embryonic development, including left-right axis formation.

45 m induction and asymmetric expression during left-right axis formation.

46 ated in dorsoanterior development, initiates left-right axis formation.

47 Abnormal left-right-axis formation results in heterotaxy, a multi

48 onal patterning, providing new insights into left/right axis formation.

49 rrhage, structural cardiac defects, abnormal left-right axis, hepatorenal and pancreatic cysts, and e

50 ellite symposium on 'Making and breaking the left-right axis: implications of laterality in developme

51 l organs are consistently oriented along the left-right axis in all vertebrates, and perturbations of

52 ligands, and are involved in regulating the left-right axis in chick, mouse and zebrafish.

53 Furthermore, the orientation of the left-right axis in conjoined twins is dependent upon whi

54 ght asymmetries, or can "rescue" a perturbed left-right axis in conjoined twins to normal orientation

55 Nodal flow orients the left-right axis in some vertebrates, and is generated by

56 ile cilia and is required for patterning the left-right axis in vertebrates.

57 hat its activity is necessary to specify the left-right axis in Xenopus and zebrafish embryos.

58 specification program that occurs across the left/right axis in the nervous system of the nematode C.

59 Formation of the left-right axis involves a symmetry-breaking signal orig

60 Development of asymmetry along the left-right axis is a critical step in the formation of t

61 of internal organs asymmetrically along the left-right axis is critical for their proper adult funct

62 Establishment of the left-right axis is essential for normal organ morphogene

63 three-dimensional vertebrate body plan, the left-right axis is linked to the dorsoventral and anteri

64 Functional diversification across the left/right axis is a common feature of many nervous syst

65 Human mutations in ZIC3 are associated with left-right axis malformations (MIM 306955, 208530, 20710

66 ne pitx2 isoform, pitx2c, in determining the left-right axis of amphibian embryos, we examined the he

67 integrin receptor in the development of the left-right axis of asymmetry in vertebrates.

68 ogy leading to a failure in establishing the left-right axis of asymmetry.

69 interactions regulate the development of the left-right axis of asymmetry; however, the identities of

70 known about molecular cues that specify the left-right axis of the body, fashioning the asymmetric m

71 tions with other molecular components of the left-right axis pathway.

72 ctions of cilia in diverse processes such as left-right axis pattern formation, cerebrospinal fluid f

73 in associated with cystic kidney disease and left-right axis patterning defects in the mouse.

74 Dawid focus on the role of FGF signaling on left-right axis patterning, showing that FGF functions a

75 ed, the embryonic mechanism that orients the left-right axis relative to the dorsoventral and anterop

76 pression of Vg1 protein can fully invert the left-right axis (situs inversus), can randomize left-rig

77 how the cilia protein Arl13b is required for left right axis specification as its absence results in

78 the mouse node is instrumental in initiating left-right axis specification and identify Nodal as the

79 ncanonical Wnt signaling with the control of left-right axis specification, and provide an entry poin

80 y central roles in mesendoderm induction and left-right axis specification, but the mechanisms regula

81 ide spectrum of phenotypes, including random left-right axis specification, polycystic kidney disease

82 mesoderm formation, anterior patterning, and left-right axis specification.

83 ion, anterior-posterior axis orientation and left-right axis specification.

84 terior-posterior axis, neural patterning and left-right axis specification.

85 rates develop distinct asymmetries along the left-right axis, which are consistently aligned with the