ライフサイエンスコーパス: leg ulcer

1 oriasis, atopic dermatitis, hand eczema, and leg ulcers.

2 (four-layer compression bandages) for venous leg ulcers.

3 implemented to improve management of venous leg ulcers.

4 th sickle cell anaemia to promote healing of leg ulcers.

5 atients with sickle cell disease and chronic leg ulcers.

6 it is equally as effective at healing venous leg ulcers.

7 ality of treatment received by patients with leg ulcers.

8 efit and harm when applied to chronic venous leg ulcers.

9 ted with or accompany avascular necrosis and leg ulcers.

10 Venous disease is the most common cause of leg ulcers.

11 in chronic, nonhealing wounds such as venous leg ulcers.

12 e functions in chronic wounds such as venous leg ulcers.

13 ds were diabetic foot ulcers (19.0%), venous leg ulcers (26.1%), and pressure ulcers (16.2%).

14 ts were aged 18 years or older with a venous leg ulcer and an ankle brachial pressure index of at lea

15 ient weight to the treatment cues of type of leg ulcer and pain.

16 Exclusion criteria included the presence of leg ulcers and receiving microsclerotherapy or foam scle

17 pain syndromes including avascular necrosis, leg ulcers, and intractable pain.

18 tory of relatively severe hemolysis, chronic leg ulcers, and mild pulmonary hypertension presented wi

19 mited evidence suggests that hydroxyurea and leg ulcers are not associated in patients with sickle ce

20 at keratinocyte migration may be impaired in leg ulcers because of a reduced availability of intact p

21 ted with elevated TRV, microalbuminuria, and leg ulcers, but these vascular complications are not ind

22 argets in the promotion of healing of venous leg ulcers, by acting at least in part through distinct

23 INTERPRETATION: Venous leg ulcers can be healed with a spray formulation of all

24 Venous leg ulcers can be very hard to heal and represent a sign

25 Wound fluid collected from chronic venous leg ulcers (chronic wound fluid (CWF)) has been shown to

26 teams or services, family doctor practices, leg ulcer clinics, tissue viability clinics or services,

27 socio-economic factors to the development of leg ulcers, despite the social patterning of many underl

28 A socio-economic gradient in venous leg ulcer disease was observed.

29 Many patients with venous leg ulcers do not heal with standard care.

30 bstantial proportion of patients with venous leg ulcers do not receive adequate compression therapy.

31 lts suggest that serine protease activity in leg ulcer fluid degrades plasminogen and support the hyp

32 issue provides a clinical overview of venous leg ulcers, focusing on prevention, diagnosis, treatment

33 crobial agents associated with better venous leg ulcer healing compared with usual care (dressings an

34 These surrogate markers for venous leg ulcer healing may allow for early clinical trials to

35 ics as candidate surrogate markers of venous leg ulcer healing using the Curative Health Services pop

36 emic antibiotic therapy with improved venous leg ulcer healing.

37 fibroblasts to evaluate their role in venous leg ulcers healing.

38 Hypertensive leg ulcer (HLU) is an inflammatory disease characterized

39 f 58,038 wounds met our definition of venous leg ulcer; however, 1550 wounds were excluded based on s

40 effective treatments are needed for chronic leg ulcers in sickle cell anaemia.

41 and with elevated TRV, microalbuminuria, and leg ulcers in SS-Sbeta(0) adults, but these associations

42 albuminuria in the whole population and with leg ulcers in SS-Sbeta(0) adults.

43 adult patients with sickle cell anaemia and leg ulcers into our trial.

44 Management of venous leg ulcers is based on understanding pathophysiologic ab

45 The evaluation of therapies for venous leg ulcers is challenged by the prolonged observation pe

46 widespread prescription, treatment of venous leg ulcers is often prolonged and recurrence rates high.

47 Patients diagnosed with incident venous leg ulcers living in the most deprived areas were less l

48 Venous leg ulcer management in the UK varies significantly.

49 es in two key areas of guideline recommended leg ulcer management, arterial Doppler assessment and co

50 One condition-specific measure, the Venous Leg Ulcer Measure, matched most closely conceptually, bu

51 entry, was present in all cases, especially leg ulcers (n = 3).

52 icular uses, such as treatment of refractory leg ulcers or reconstruction after skin cancer excision.

53 ion defects of fibroblasts from human venous leg ulcer patients can be reversed by ultrasound, demons

54 suggest that the inequalities experienced by leg ulcer patients may be exacerbated by reduced access

55 Using a large cohort of diverse venous leg ulcer patients, we demonstrate that after only 4 wk

56 were further investigated, 11 had attended a leg ulcer/podiatry clinic.

57 culopathy, including pulmonary hypertension, leg ulcers, priapism, chronic kidney disease, and large-

58 gitant jet velocity [TRV], microalbuminuria, leg ulcers, priapism, stroke, and osteonecrosis) by clin

59 We recorded a dose-dependent decrease in leg ulcer size (p=0.0012) and pain (p<0.0001).

60 Hydroxyurea induces painful leg ulcers that are usually difficult to treat and requi

61 plasminogen is degraded by fluid from venous leg ulcers to a number of fragments, including kringle d

62 fferences in the incidence and prevalence of leg ulcers using negative binomial regression.

63 Patients with venous leg ulcers (VLUs) have calf muscle pump dysfunction, whi

64 ted at the epidermal wound margins of venous leg ulcers (VLUs).

65 ound to be upregulated in non-healing venous leg ulcers (VLUs).

66 GS: In wound edge biopsies from human venous leg ulcers we found a striking upregulation of dermal N-

67 14 patients with extremely painful leg ulcers were identified.

68 from biopsies of the edge of chronic venous leg ulcers, were compared with normal fibroblasts grown

69 The overall rates of people with venous leg ulcers who were documented as receiving guideline re

70 esda, MD, USA) with sickle cell anaemia with leg ulcers (with a surface area of 2.5-100 cm(2)) persis