ライフサイエンスコーパス: leptotene

1 R-specific events, not SC formation, at late leptotene.

2 ted by Spo11-dependent DSBs that form during leptotene.

3 pt that in this case Rad51 was detectable at leptotene.

4 n of AtMSH5 to meiotic chromosomes occurs at leptotene and is dependent on DNA double-strand break fo

5 irth when type A and B spermatogonia and pre-leptotene and leptotene spermatocytes are present.

6 Spo11 localizes to discrete foci during leptotene and to homologously synapsed chromosomes.

7 Leptotene and zygotene (L/Z) spermatocytes are not compe

8 ated extensively with chromatin loops during leptotene and zygotene and showed preferential binding i

9 became particularly enriched during meiotic leptotene and zygotene in germline chromatin of Tetrahym

10 forming synaptonemal complexes (SCs) during leptotene and zygotene of meiosis.

11 The number of DNA breaks detected rose as leptotene and zygotene spermatocytes populate the testis

12 wed us to further localize cyclin B3 mRNA to leptotene and zygotene spermatocytes.

13 nscription of genes that are markers for the leptotene and zygotene stages, but not genes that are ma

14 tages of germ cells at early meiotic stages (leptotene and zygotene) but lower percentages at later s

15 found in wild type (WT) meiosis during late leptotene and zygotene, was missing in the ask1-1 mutant

16 oposal: Group II organisms use the repair of leptotene breaks to promote synapsis by generating doubl

17 taposition of homologous chromosomes at late leptotene/early zygotene are essential steps before chro

18 lustering) at the nuclear periphery in early leptotene, leading to formation of the telomere bouquet.

19 is expressed solely in germ cells during the leptotene-pachytene stages of spermatogenesis.

20 of the endogenous ldhc gene is restricted to leptotene/pachytene primary spermatocytes.

21 vealed that when chromosomes condense during leptotene, Rad51 is diffuse within the nucleus.

22 g" of the BTB above a migrating preleptotene/leptotene spermatocyte and the "resealing" of the barrie

23 ccommodate the migration of preleptotene and leptotene spermatocytes across the BTB during spermatoge

24 A and B spermatogonia and pre-leptotene and leptotene spermatocytes are present.

25 stis barrier (BTB) to migrating preleptotene/leptotene spermatocytes at stage VIII of the epithelial

26 enesis in the mammalian testis, preleptotene/leptotene spermatocytes differentiate from type B sperma

27 is to facilitate the transit of preleptotene/leptotene spermatocytes is not known.

28 o their depletion and formation of fewer pre-leptotene spermatocytes.

29 to accommodate the migration of preleptotene/leptotene spermatocytes.

30 rogrammed DSB induction is defective in Mei1 leptotene spermatocytes.

31 mble their AEs, and arrested as early as the leptotene stage of prophase I, demonstrating that cohesi

32 ormation of DSBs, which are initiated at the leptotene stage.

33 osis but fail to progress beyond zygotene or leptotene stage.

34 and is manifest at spermatogonia and/or pre-leptotene-stage cells, which facilitates PRDM9 binding a

35 matogenesis with an onset at preleptotene or leptotene stages of meiosis.

36 At the end of leptotene, telomeres clustered de novo at the nuclear pe

37 e course of meiosis showed that the onset of leptotene, the first stage of prophase I, frequently occ

38 At the onset of leptotene, the replicated sister chromatids are organize

39 assed through premeiotic interphase and into leptotene, there was an increase in the frequency of lar

40 By leptotene, there was no obvious evidence of telomere gro

41 is associated with meiotic chromosomes from leptotene through to early pachytene.

42 estis with a peak at day 14 postpartum, when leptotene, zygotene, and early pachytene spermatocytes a

43 it regulates the transition through a novel leptotene-zygotene checkpoint, a key step in early meiot

44 rly meiotic prophase I when it regulates the leptotene-zygotene progression.

45 e II activity that are initially detected in leptotene-zygotene spermatocytes just preceding the form

46 Telomeres associate with the NE during the leptotene-zygotene transition but cluster slowly if at a

47 tromeres vs. telomeres in the nucleus at the leptotene-zygotene transition is the same in mutant and

48 BR2(-/-) spermatocytes were arrested between leptotene/zygotene and pachytene and died through apopto

49 matogenesis of normal mice, where only a few leptotene/zygotene spermatocytes I with clustered telome

50 nes and proteins in enriched preparations of leptotene/zygotene spermatocytes, prepubertal and adult

51 -biotin nick end labeling, and Rad51) at the leptotene/zygotene stages of spermatocytes.

52 ope to transiently form a cluster during the leptotene/zygotene transition (bouquet arrangement).

53 with the maintenance of homolog bias at the leptotene/zygotene transition of meiotic prophase.