ライフサイエンスコーパス: lesion

1 ed procedure, capsule retention, or a missed lesion.

2 The child underwent total excision of the lesion.

3 quency of primer synthesis downstream of the lesion.

4 whether they had PCI of an SVG or a non-SVG lesion.

5 least 3 months, and at least one measurable lesion.

6 ged telencephalon, mostly suddenly after the lesion.

7 in 21 (88%) LM or LMM and in 3 (77%) benign lesions.

8 y of shear wave propagation (QSWP) in breast lesions.

9 g scene discrimination following hippocampal lesions.

10 monstrated longitudinally extensive myelitic lesions.

11 to accurately visualize and target prostate lesions.

12 reased significantly in hyperplastic and SCC lesions.

13 onography, many of which were flat, serrated lesions.

14 markedly upregulated in human psoriatic skin lesions.

15 of 12 months or longer for the remaining 140 lesions.

16 ial diagnosis of malignant and benign breast lesions.

17 ess the stability of Treg function in ocular lesions.

18 g potential overtreatment of suspicious skin lesions.

19 stabilization and exclusion of Rad9 from DNA lesions.

20 model of imiquimod-induced psoriasiform skin lesions.

21 of spontaneous choroidal neovascularization lesions.

22 number within widespread erythrokeratodermic lesions.

23 K-Ras(G12V) induced lung tumors and gastric lesions.

24 om 157 (64.1%) underwent PD for nonmalignant lesions.

25 phase ensues where 30% develop severe heart lesions.

26 thological images of papillomavirus infected lesions.

27 bition points to R-loops as precursors for R-lesions.

28 multifocal disease with genetically distinct lesions.

29 reduced glandular secretory activity of the lesions.

30 e misreplication of structurally diverse DNA lesions.

31 hageal adenocarcinoma (EAC) and precancerous lesions.

32 ic tumours versus normal skin or benign skin lesions.

33 deregulated miRNAs shared by both neoplastic lesions.

34 tion were demonstrated in the core of FCD-II lesions.

35 ty was correctly identified in 87% of atrial lesions.

36 spectively) than those without frontal brain lesions (1/11, P's < 0.05).

37 Results A total of 654 lesions (420 in the PZ) were detected.

38 r both brain and spinal gadolinium-enhancing lesions (62.5pg/ml, IQR = 42.7-71.4) had higher sNfL tha

39 we randomly assigned 1398 patients with 2030 lesions; 703 patients with 1037 lesions were assigned to

40 mice manifested increased mitochondrial DNA lesions (8-oxoguanine) exclusively localized to glomerul

41 oups with a total of 151 local recurrent HCC lesions abutting the diaphragm.

42 This study shows that focal lesions affect the brain's ability to represent stimuli

43 d nephropathy, the classic HIV-driven kidney lesion among individuals of African descent, has largely

44 In a voxel-based lesion analysis, the difference between erectile dysfunc

45 Complex target-lesion anatomy is associated with increased ischemic eve

46 current treatment options affect the dynamic lesion and exercise hemodynamics in general.

47 herogenesis in Apoe (-/-) mice by regulating lesion and systemic inflammation.

48 erial/A total of 100 patients with no breast lesions and a total of 100 patients with malignant breas

49 s have also been detected in atherosclerotic lesions and arterial thrombi in humans and mice.

50 of high-risk (hr) HPV-associated high-grade lesions and carcinomas in the anogenital region and orop

51 proinflammatory CD11c(+) macrophages within lesions and controlling the expansion of the necrotic co

52 d postoperative detection of prostate cancer lesions and have high potential for future clinical tran

53 ions that are seen within later precancerous lesions and in established malignancy can also occur in

54 study was to assess microglial activation in lesions and in normal-appearing white matter (NAWM) of m

55 s in mRNA abundance in healthy lung and lung lesions and in the lymphoid tissues bronchial lymph node

56 tus in human ductal carcinoma in situ (DCIS) lesions and invasive breast cancers as well as with incr

57 ression of Claudin-2 in EAC and precancerous lesions and its association with VDR and TGR5 expression

58 y of the various ischemic fundus and retinal lesions and of the optic disc during the acute phase sho

59 We examined multiple sclerosis lesions and other central nervous system pathologies wit

60 ging characteristics of inflammatory NTZ-PML lesions and PML-IRIS to determine differentiating and ov

61 o adjacent skin, thus leading to larger skin lesions and satellite lesions in IL-1R1(-/-) mice.

62 V alone, effectively tracks metastatic tumor lesions and significantly prolongs the survival of brain

63 ere the change in the mean number of mucosal lesions and the number of subjects with large erosions a

64 (SWATC) display for the diagnosis of breast lesions and to identify factors associated with the qual

65 ions enhanced on T1-weighted MRI ["enhancing lesions"], and cumulative combined number of unique lesi

66 he occurrence of macrophage-like SMCs in the lesions, and impaired cholesterol efflux.

67 Our results suggest that lesions appeared due to changes in the coral pathobiome

68 During active disease, the CC-slab lesion area was larger than both the ONL-slab and fundus

69 oth the ONL-slab and fundus autofluorescence lesion areas.

70 -) mice showed reduced aortic arch and sinus lesion areas.

71 Here we characterize the different lesions arising from each Cas9 variant and the resulting

72 US revealed hypoechoic lesions around the mediastinum testis with hypervascular

73 Incidence of atrophic lesions as determined by fundus autofluorescence.

74 f C. difficile flagella in eliciting mucosal lesions as long as the toxins exert their action on the

75 of (18)F-FMISO kinetic parameters for NSCLC lesions as well as for normal lung and muscle.

76 Reduction in size of lesions as well as subjective improvement of symptoms.

77 Among the multitude of lesions associated with disease, the most common seem to

78 Wider midsagittal tissue bridges and smaller lesions at 1 month post-injury were associated with neur

79 multifocal cancer in the right breast, with lesions at 1:00 and 4:00, the largest measuring approxim

80 Consistent with this idea, some structural lesions at both E402 and R404 produced signaling behavio

81 primary end point was the detection of bone lesions at diagnosis by MRI versus PET-CT.

82 dal neovascularization, acquired vitelliform lesions (AVLs), and geographic atrophy (GA); and ultrast

83 ity may have prevented its identification in lesion-based studies of auditory comprehension.

84 e (2 papers, sensitivity of DOTATOC on a per-lesion basis was 100%, for (111)In-octreotide it was 78.

85 Secondarily, progeny lesions became ossified (n = 7) while at the same time f

86 Qualitative and quantitative analyses on lesion boundary and area using a semi-automated MATLAB a

87 on), lesion contrast (after reconstruction), lesion boundary sharpness (average normalized gradient a

88 ry sharpness (average normalized gradient at lesion boundary), and contrast-to-noise ratio (CNR) were

89 of CCM3 loss in vivo, significantly reducing lesion burden and extending longevity.

90 of animals with CI developed pre-neoplastic lesions, but cancer was not observed in any TP53(+/+) an

91 ry T cell subset in vitro that mainly drives lesions, but not regulatory T cells.

92 we demonstrate a mechanism by which a single lesion can cause a complex neuropsychiatric syndrome bas

93 oma, spontaneous or orthotopically implanted lesions can be imaged, and tumor morphology and size can

94 RNS-induced DNA lesions cause genomic instability in the absence of Brca

95 In the cortex, focal lesion changes might precede diffuse atrophy with cortic

96 2 score to better understand false-negative lesion characteristics.

97 gh ASCUS, low-grade squamous intraepithelial lesions, CIN1, and CIN2 (18%-25%), up to 41%-47% for CIN

98 tric gliomas present as benign, slow-growing lesions classified as grade I or II by the WHO classific

99 the characterization of small (1-4 cm) renal lesions compared with conventional attenuation measureme

100 etected 95% of malignant/severely dysplastic lesions, compared with 35% and 50% for carcinoembryonic

101 ite treatment improvements, associated renal lesions - congenital dysplasia, acquired scarring or bot

102 The remaining 390 lesions constituted the ITT population.

103 Image noise (pixel standard deviation), lesion contrast (after reconstruction), lesion boundary

104 How a single brain lesion could cause such a complex disorder is unclear, l

105 henomena and thus to understand how the same lesion could produce two opposite effects on body temper

106 as9 was developed such that targeted genomic lesions could be introduced in vivo with unprecedented e

107 performed to determine whether age and brain lesion count were associated with adrenal findings in pa

108 (SUVmax, r(2) = 0.97; SUVmean, r(2) = 0.88; lesion count, r(2) = 0.97).

109 lesion synthesis opposite the UV-induced DNA lesion cyclobutane pyrimidine dimer and was recently fou

110 The individual lesion detection algorithms were combined using a partia

111 nt clinical setting, abrupt cutoff of a skin lesion determined by an examination of a dermatologist.

112 Patients with or without linear lesions did not differ significantly with respect to sex

113 MRI brain lesion distribution criteria were able to distinguish RR

114 We revealed that the central retinal lesions either do not impair motion detection or even re

115 on T2-weighted MRI, cumulative number of new lesions enhanced on T1-weighted MRI ["enhancing lesions"

116 ount for the marked axonal growth across the lesion epicenter.

117 y reducing macrophage-mediated injury at the lesion epicenter.

118 g a precise localization of nonpalpable DCIS lesions even more important.

119 Cells facing the lesion exhibited increased filamentous actin staining, i

120 n and chitin accumulation in hyphal tips and lesion expansion on wounded hosts, but significantly pro

121 n in the bone marrow and enhanced osteolytic lesion formation, irrespective of HIF-1 Conversely, sile

122 the bone marrow and tumor-driven osteolytic lesion formation.

123 isms that are at least partly independent of lesion formation.

124 l samples (n = 10), as well as fibrotic skin lesions from localized scleroderma and uninvolved skin (

125 Interestingly, histological analysis of lung lesions from Muc4(ko)/NDL mice revealed a reduced associ

126 In skeletal lesions from patients with metastatic PCa, histological

127 ision repair that preferentially removes DNA lesions from the template strand that block translocatio

128 Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (

129 s inactivation during the induction of a DNA lesion, generate abnormal oscillatory SPB movements that

130 Compared with controls, monkeys with VS lesions had deficits in learning to select rewarding ima

131 formed by Rad3/ATR checkpoint kinase at DNA lesions; however, the putative scaffold interactions inv

132 ed the effects of five carboxymethylated DNA lesions, i.e. O6-CMdG, N6-CMdA, N4-CMdC, N3-CMdT and O4-

133 etabolic activity at FDG PET in the residual lesion identified at brain MR imaging and survival time

134 high (99m)Tc-PSMA-I&S uptake in all suspect lesions identified in previous (68)Ga-HBED-CC-Ahx-KuE ((

135 h CCM, 9 (75%) had a single Zabramski type 2 lesion in a supratentorial location.

136 nation of a focal, lysolecithin-demyelinated lesion in adult male mice.

137 Tumors were the second most common lesion in both groups.

138 aoperative findings, followed by parathyroid lesion in the inferior position and parathyroid lesion s

139 the temporal pole is not commonly completely lesioned in stroke survivors and this heterogeneity may

140 Of 65 animals evaluated, we identified lesions in 20 animals (30.7%).

141 Twenty-two lesions in 3 patients were identified.

142 ned based on detection of Marsh 2 or greater lesions in biopsy specimens or persistent high levels of

143 e to LPS, we studied rats with small thermal lesions in different parts of the DMH.

144 d medium-wavelength UV light can cause photo-lesions in DNA origami.

145 leading to larger skin lesions and satellite lesions in IL-1R1(-/-) mice.

146 successful visualization of prostate cancer lesions in men using (68)Ga-NeoBOMB1 and PET/CT.

147 uated in their ability to generate cutaneous lesions in mice.

148 To detect and quantify peripheral nerve lesions in multiple sclerosis (MS) by magnetic resonance

149 based on segmentation of bones in CT and of lesions in PET.

150 we evaluated the severity of myelin deficit lesions in rhesus monkey brain induced by experimental a

151 tical neurons transplanted immediately after lesions in the adult mouse motor cortex restored damaged

152 A clinical examination revealed nodular lesions in the ears and a lump in the subcutaneous tissu

153 ects in anatomy result in defined functional lesions in the larval heart, implicating mechanical sign

154 discovered, however, that small electrolytic lesions in the midbrain severely impair a chicken's abil

155 Eleven patients (26%) had a combination of lesions in the posterior pole.

156 Abscesses were the most common lesions in the prevertebral space.

157 mal skinfold microbiota were associated with lesions independently of gender, duration and familial h

158 st quantitative human genome-wide map of DNA lesions induced by ultraviolet (UV) radiation, the ubiqu

159 Because lesion-induced symptoms can come from sites connected to

160 , psychiatric disease, dementia, or a second lesion is required.

161 ery of antifungals to hyphae within necrotic lesions is thought to contribute to therapeutic failure

162 ity in a region of motor cortex that, before lesions, is not essential for manual skills, but becomes

163 microenvironment of precancerous pancreatic lesions, known as pancreatic intraepithelial neoplasms (

164 had diabetes mellitus, 41% were women, mean lesion length was 8.3 cm, and 44% were severely calcifie

165 sensitive for quantitative measurements and lesion localization.

166 ymptoms can come from sites connected to the lesion location and not just the lesion location itself,

167 cTnT levels on admission were not related to lesion location anywhere within the anterior circulation

168 cted to the lesion location and not just the lesion location itself, we also identified brain regions

169 brain regions functionally connected to each lesion location.

170 brain regions functionally connected to the lesion locations.

171 logic examination, 80 clinically unimportant lesions (<5 mm; Gleason score, 3+3) were excluded.

172 propose that targeted delivery of GD1a to MS lesions may act as a potential novel molecular tool to b

173 air protein counteracting oxidative promoter lesions may modulate gene expression.

174 of progression using the growth of atrophic lesions measured by fundus autofluorescence.

175 coinciding with secondary energy failure, in lesioned mice compared to controls.

176 Lesioned mice showed normal motor coordination, balance,

177 ed, repetitive behaviors were exacerbated in lesioned mice.

178 Those lesions might stabilize intermediate receptor conformati

179 ethane (AOM)-induced precancerous colorectal lesion model in rats.

180 Second, lesion network mapping was used to identify brain region

181 "], and cumulative combined number of unique lesions [new enhancing lesions on T1-weighted MRI plus n

182 ncluding incubation period, lesion size, and lesion number.

183 h a number of similar observations of healed lesions observed in trilobites.

184 monitored oxidatively induced clustered DNA lesions (OCDL), DNA double-strand breaks (DSB), apoptosi

185 In addition, lesions of the amygdala reduce cataplexy.

186 and unilateral Bdnf knockdown accompanied by lesions of the contralateral amygdala impede goal-direct

187 Lesions of the RMTg reduced both the number of DA neuron

188 Cystic lesions of the transplant pancreas developed in 22 patie

189 n part the heterogeneous fates of metastatic lesions often observed in the clinic post-therapy.

190 f rhesus macaques with ventral striatum (VS) lesions on a two-arm bandit task that had randomly inter

191 redominant perivascular gadolinium enhancing lesions on magnetic resonance imaging that were discrimi

192 e factors associated with missed parathyroid lesions on preoperative 4D-CTs and to investigate patter

193 ting cases of small foci suspicious of lytic lesions on skull radiographs, seen as arachnoid granulat

194 ined number of unique lesions [new enhancing lesions on T1-weighted MRI plus new and newly enlarged l

195 T1-weighted MRI plus new and newly enlarged lesions on T2-weighted MRI]).

196 ve scarring, more than 10 lesions, or active lesions on the face, hands, or feet.

197 was applied topically to a designated target lesion once per day for 4 consecutive days on days 1 thr

198 and dystonia involves the placement of focal lesions or the application of deep brain stimulation (DB

199 also required to have scarring, more than 10 lesions, or active lesions on the face, hands, or feet.

200 ssociation of ART with longitudinal cervical lesion outcomes.

201 njury, scar elements and vessels entered the lesions over the next 7 d, as did large numbers of axons

202 ver, promoted efficient tracer uptake in PCa lesions over time and led to steadily increasing lesion-

203 AF is associated with specific WMH lesion pattern among patients with embolic stroke aetiol

204 evaluating the predictive value of acute MRI lesion patterns for discriminating clinical outcome in t

205 et reactivity (HPR) in SVG PCI versus native lesion PCI is unknown.

206 our DNA is challenged with at least 100,000 lesions per cell on a daily basis.

207 In ACS, FFR was performed in 1.4 lesions per patient, mostly in left anterior descending

208 ly known about how the carboxymethylated DNA lesions perturb DNA replication in human cells.

209 , later scans may be beneficial because most lesions present with higher uptake and contrast.

210 Here, for the first time, we report carious lesions preserved in specimens of A. simus, recovered fr

211 activation at the site of focal inflammatory lesions, presumably by preventing leukocyte trafficking

212 Following brain lesions, previously normal patients sometimes exhibit cr

213 It provides lesion quantification equivalent to that of visual asses

214 A high correlation between bone lesion quantity as determined visually and automatically

215 ompound 49 displayed oral efficacy in 6-OHDA lesioned rat model of Parkinson diseases.

216 e reader exceeded 75% for each reader at the lesion, region, and subject levels.

217 riving BRAFV600E(+) LCH cell accumulation in lesions remain unknown.

218 escent material gravitated within the larger lesions, resulting in typical curvilinear deposits chara

219 Clinically driven target lesion revascularization occurred for 77 DCS and 136 BMS

220 MVO was a strong predictor of target lesion revascularization occurrence (P=0.017 for log-ran

221 activated by peripheral stimulation and LHb lesions reversed the inhibitory effects on cocaine locom

222 ntiating between malignant and benign breast lesions, RTE findings were compared with histopathology

223 plex neuropsychiatric syndrome based on that lesion's unique pattern of functional connectivity, with

224 he remaining 16 patients without obvious MRA lesions showed neither TTP nor TSA time delay.

225 ely unaffected, although repopulation of the lesion site by astrocytes was delayed significantly.

226 he biosynthesis of SPM is not induced in the lesion site up to 2 weeks after injury.

227 ore and after stroke was correlated with the lesion site using t-test statistics.

228 availability of neurotrophic factors in the lesion site, thereby promoting axonal regeneration and l

229 Clinical lesion size and area, LM and LMM area based on HRCM-RV f

230 in MGAS315 synergistically reduced the skin lesion size and GAS burden in the liver and spleen.

231 s followed by type I IFN treatment increased lesion size and parasite burden, quantitatively reproduc

232 ion in the inferior position and parathyroid lesion size of 10 mm or less.

233 No such difference in bacterial load or lesion size was detected in galectin-3(-/-) mice, which

234 ost resistance, including incubation period, lesion size, and lesion number.

235 tors such as baseline performance, hand use, lesion size, mood, fatigue, or whether distraction was t

236 in-3(-/-) mice, which overall showed smaller lesion sizes than the galectin-3(+/+) animals.

237 ance status (0 v >/= 1), size of the largest lesion (smaller), and KIT mutation (exon 11) were signif

238 determined in skin biopsy specimens from all lesions stained with hematoxylin-eosin and immunohistoch

239 Little is known about which lesion subtypes may serve as CRC precursors in young adu

240 mbined voxel-based-and structural connectome-lesion symptom mapping approach, since cortical dysfunct

241 se carotid arteries with established intimal lesions tailored to resemble the substrate of human erod

242 criminate high-risk versus low-risk coronary lesions than [(18)F]FDG.

243 e highly-expressed in EAC, SCC and glandular lesions than in SE and more in EAC than in BE and CM.

244 We report that, after a chemical lesion that ablates inner retinal neurons, regenerated r

245 ggered by a distinct type of atherosclerotic lesion that displays features of impaired inflammation r

246 We find that Rh-PPO binding induces a lesion that triggers the DNA damage response (DDR).

247 s neoplasias (IPMNs) are precancerous cystic lesions that can develop into pancreatic ductal adenocar

248 ting that the closer a region is to a stroke lesion, the more it would be affected during functional

249 Concurrent with the appearance of "egg-yolk lesions," the OCT showed a cleft in the outer retina, cr

250 deposits within the brain and the spongiform lesions they induce.

251 d along this dimension and applied a virtual lesion to the left anterior temporal lobe.

252 More specifically, we found ReRh lesions to produce (1) a pronounced and long-lasting dec

253 ons over time and led to steadily increasing lesion-to-background ratios up to 21 h after injection.

254 en global cognitive and fluency performance, lesion topography, and ultrastructural damage were asses

255 Lesion transmurality was correctly identified in 87% of

256 These lesions typically appear first in the perifoveal macula,

257 g HRCM-RV, and 22 patients with 23 LM or LMM lesions underwent staged surgery and contributed to the

258 lesions, which may contribute to an impaired lesion vascularization and growth.

259 The first evidence of prostate cancer lesion visualization in men using (68)Ga-NeoBOMB1 and PE

260 devices, but there was a correlation between lesion volume and neurocognitive decline (p = 0.0022).

261 g white matter distribution volume ratio, T2 lesion volume and normal-appearing white matter magnetiz

262 g (MRI) at 6 months and 24 months (change in lesion volume on T2-weighted MRI, cumulative number of n

263 lained over 90% of the variance in enlarging lesion volume over the subsequent 1 year.

264 and cognitive performances, with cerebellar lesion volume, cerebellar Lobules VI, Crus I and VIIIa a

265 as correlated with enlarging T2-hyperintense lesion volumes over the subsequent year (rho = 0.59, P =

266 Using the SWATC display, the QSWP of each lesion was assigned to a two-point scale: score 1 (low q

267 daily for 8 to 12 weeks, when the nonculprit lesion was reimaged and intervention performed.

268 etection for PI-RADS category 2, 3, 4, and 5 lesions was 15.7%, 33.1%, 70.5%, and 90.7%, respectively

269 The median SUVmax of 94 tumor lesions was 7.3 (range, 1.6-59.5).

270 lower limbs without pain, swelling, or skin lesions was noted at physical examination.

271 inction between symptomatic and asymptomatic lesions was suggested.

272 lat colorectal polyps or laterally spreading lesions, we associated rectosigmoid location, combined P

273 ity and specificity for diagnosing malignant lesions were 86% (CI 95%; 70-95) and 76% (CI 95%; 60-87)

274 Selected lesions were also examined by scanning and transmission

275 ts with 2030 lesions; 703 patients with 1037 lesions were assigned to MiStent, of whom 697 received t

276 e index procedure, and 695 patients with 993 lesions were asssigned to Xience, of whom 690 received t

277 Results A total of 210 lesions were benign, 43 were GS 6, and 90 were GS >/=7.

278 A total of 701 lesions were concordantly detected on both (64)Cu-DOTATA

279 However, more advanced right-sided lesions were detected at follow-up CT colonography, many

280 ke were quantified using SUVmaxPSMA-positive lesions were detected in 12 of 12 prostate cancer patien

281 s were followed for >80 weeks and pancreatic lesions were evaluated histologically and immunohistoche

282 TATOC PET/CT scans, whereas an additional 68 lesions were found by only one of the scans.

283 with SPMS (35%) than RRMS (23%), but active lesions were found in all patients, including those on h

284 MRI features were the following: all lesions were hypointense on T2- and hyperintense (n=12)

285 Choroidal lesions were identified and analyzed in four of six eyes

286 A higher proportion of lesions were inactive in patients with SPMS (35%) than R

287 total of 100 patients with malignant breast lesions were included in the study.

288 rficial femoral artery stenotic or occlusive lesions were randomized to treatment with plain balloon

289 er repair of tetralogy of Fallot and similar lesions were studied echocardiographically (n=23) and by

290 One hundred fifteen patients with lung lesions were then prospectively included and assessed wi

291 ridization at 1, 4, 7, and 15 days after the lesion, were increased in the damaged telencephalon, mos

292 y low in tissue and myelin at 3-5 days after lesion when axons regenerate.

293 was seen except in the case of parotid space lesions where female predominance was seen.

294 tuosity increased significantly in high-risk lesions, whereas diameter decreased significantly in hyp

295 2 suppresses vasculogenesis in endometriotic lesions, which may contribute to an impaired lesion vasc

296 Distinct spectral profiles were observed for lesions with IDH-mutated genotypes, between astrocytoma

297 ere included as a representation of indolent lesions with limited invasive capacity.

298 Skin lesions with pruritic vesicles on an erythematous base w

299 Two readers correlated mapped lesions with reports of prospectively read MP MR images.

300 eks of treatment, and clinical resolution of lesions within 2 months.