ライフサイエンスコーパス: lessen

1 racial disparities in clinic attendance were lessened.

2 er injury the adverse effects of obesity are lessened.

3 CCL2/MCP-1, hMMP7, and hTNF-alpha, were also lessened.

4 exchanging with strangers are substantially lessened.

5 rtened and the inhibition of EC migration is lessened.

6 -Asp19Gly, although the antiviral effect was lessened.

7 .0005), and secondary astigmatism (P < .005) lessened.

8 ivation of 5-HT1A autoreceptors, which would lessen 5-HT neuron firing, contributes to cocaine-seekin

9 presented in an accompanying appendix do not lessen a paper's impact.

10 p of the beta-hairpin, was attributable to a lessened ability of these variants to insert into membra

11 e results indicate that silver ion sinks may lessen AgNP impacts on natural microbial ecology relativ

12 in levels, reduced bacterial overgrowth, and lessened alcoholic steatohepatitis.

13 Blockade of OX40L significantly lessened allergic responses to HDM or peanut.

14 uld be an additional therapeutic strategy to lessen alpha-synuclein burden in synucleinopathies.

15 A30P is known to lessen alpha-synuclein/membrane affinity and, consistent

16 sis services in India and South Africa could lessen, although not eliminate, the catastrophic financi

17 targeted genetic selections were employed to lessen and finally eliminate B protein-dependence.

18 imit genetic growth potential appear to have lessened, and variation in height by socioeconomic posit

19 almitoylation and ERK phosphorylation, while lessening apoptosis in HPHG treated ECs.

20 is compressed into the last years of life or lessened as people age.

21 Shared genetic influence lessened as the distance between depth measurements was

22 as in NIHSS scores was observed but this has lessened as the documentation of NIHSS has improved in r

23 on in turn was limited as a consequence of a lessened availability of nuclear-localized signal transd

24 inding motif or Atp8b1 gene transfer in mice lessened bacteria-induced lung injury and improved survi

25 To lessen barriers and facilitate renal transplantation, bl

26 , whereas removal of just iron significantly lessens binding.

27 tillation ameliorated bladder hyperactivity, lessened bladder mucosa damage, and decreased interstiti

28 n, diminished tumor-mediated osteolysis, and lessened bone density decrement in mice injected with br

29 e progression of cerebrovascular disease and lessen both the frequency and impact of ischemic events.

30 ockdown improved brain function recovery and lessened brain contusion volume after trauma.

31 These barriers may be lessened by greater education of the public and health c

32 strated that this "dynamic range problem" is lessened by neural adaptation, whereby neurons adjust th

33 The pain of chronic pancreatitis may be lessened by operative intervention and possibly radiatio

34 quasi-reversible, and that it can be greatly lessened by simple modifications of the solar cell opera

35 trogenic hypoglycemia in T1D humans could be lessened by targeting metabolic pathway(s) associated wi

36 hibitory effects of the DeltaH proteins were lessened by the coexpression of the internal scaffolding

37 The strength of these findings is lessened by the lack of systematically collected data us

38 the SNP for response or side effects was not lessened by the presence of cognitive impairment.

39 ogenesis by sulfate-reducing bacteria may be lessened by the presence of large labile DOC pools that

40 these regions the degree of inflammation is lessened by widespread concurrent infection with gastroi

41 y increased median survival of mice with HF, lessened cardiac fibrosis, reduced gene expression of se

42 lessens the severity of the HF phenotype by lessening cardiac fibrosis, improving molecular and stru

43 In wild-type cells, Jak1 degradation lessens CD4+ cell sensitivity to cytokines during TCR st

44 Moreover, depletion of fibrinogen lessened cerebral amyloid angiopathy pathology and reduc

45 ecent studies indicate that mild hypothermia lessens cerebral palsy risk in term infants with moderat

46 choline supplementation might significantly lessen cognitive dysfunction in DS and reduce cognitive

47 abnormalities in this region could result in lessened concern (frequently ascribed to minimization an

48 on was not better than either agent alone in lessening confirmed Expanded Disability Status Scale pro

49 advantages of an AV fistula attempt strategy lessened considerably among older patients, particularly

50 B influenza preexposure, and the correlation lessened considerably over time.

51 d postoperatively may improve acute pain and lessen conversion to chronic pain.

52 outcomes, improves future independence, and lessens costs from provincial and societal perspectives.

53 an prevent ROS release from the active site, lessen damage to the protein, and produce higher total t

54 that reducing greenhouse gas emissions could lessen damages by $1.3 billion this century.

55 ss of compound is worthy of further study to lessen diabetes complications but that dosage needs cons

56 at lower but not higher doses, significantly lessens diabetes-associated atherosclerosis with reducti

57 Recent show line selection might have lessened differences in impulsivity between breeds.

58 necrosis factor receptor, has been shown to lessen disease severity in adult patients with psoriasis

59 ment with an antibiotic and CC-3052 not only lessened disease but also improved bacterial clearance f

60 Interventions that lessen disparities in adherence may be more effective in

61 ities in suppression than interventions that lessen disparities in constancy.

62 for both attendance measures, the impact of lessening disparities in adherence may be overstated.

63 Lessening disparities in adherence or constancy lowered

64 P values can be reframed to lessen distortions by presenting them without reference

65 resulted in increased bacterial efflux pumps lessening drug concentrations, up-regulated enzymes modi

66 riceal eradication as rapidly as possible to lessen early rebleeding while minimizing ligation-induce

67 he relative collagen portion of the lesions; lessened elastin fragmentation, increased the total elas

68 Results suggest lessened enthusiasm for genetic information that maintai

69 m prophylaxis after a first manic episode to lessen episode recurrence, allow cognition to recover to

70 Rising temperatures and lessening fresh water supplies are threatening agricultu

71 Our results suggest that insulin resistance lessens fuel toxicity in the stressed heart.

72 missions offers an additional opportunity to lessen future climate change.

73 lt in improved glucose tolerance and notably lessened hepatic steatosis in the mouse model.

74 dhesion and reduced chemotaxis in vitro, and lessened homing to lymph nodes in vivo.

75 st controversial as the risk of pathology is lessened, however the risk of vesicoureteral reflux and

76 accompanying mitochondrial superoxide levels lessens hyperalgesia and LTP induction.

77 that portal (Po) vein insulin delivery would lessen hypoglycemia.

78 ferential insulin analogs), should therefore lessen hypoglycemia.

79 The Dexmedetomidine to Lessen ICU Agitation (DahLIA) study was a double-blind,

80 Blockade of type 1 interferon significantly lessens IL-10 and PD-1/PD-L1, allows normal secondary ly

81 countermeasures to preserve muscle function, lessen illness, and hasten the recovery of critically il

82 Furthermore, repression was significantly lessened in a mutant unable to produce propionyl-CoA, wh

83 change in vessel diameter following FUS was lessened in amyloid coated vessels.

84 n and liver lipid accumulation were markedly lessened in Lcn2(-/-) mice.

85 m aggregate growth rate decreased due to the lessening in the available surface of the HemNPs that CN

86 ntervention can have broad consequences that lessen inequalities in achievement and health.

87 genetic inhibition of apoptosis and necrosis lessens infarct size and improves cardiac function in th

88 whether the inhibition of JAK function might lessen inflammation in murine models of the disease.

89 depletion therapy for joint arthritis flares lessens inflammation by increasing lymphatic drainage an

90 ng and extensive degradation of PG fragments lessen inflammatory responses and may be advantageous fo

91 he capacity of the collateral circulation to lessen injury in occlusive vascular disease depends on t

92 onstantly intervening God in the Middle Ages lessened interest in the inherent features of nature tha

93 trate aerosols would improve air quality and lessen interference with the hydrologic cycle, but lead

94 ptic nerve head morphology and significantly lessened intraocular pressure elevation.

95 that constitutive activation results from a lessened intrinsic barrier that restrains spontaneous co

96 detectable analytes and has the potential to lessen ionization matrix effects in ADI-MS analyses.

97 They lessen ischemic tissue injury by serving as endogenous b

98 enhance this effect, and might have actually lessened it.

99 this potential bias and suggest methods for lessening it.

100 ation and development of an active phase and lessen its intensity.

101 vent LID and very few drugs are available to lessen its severity, thus representing a major clinical

102 est in new automation that could potentially lessen labor demands for specimen processing.

103 del, not BMSCs but adult HCs transplantation lessened liver injury, recovered liver function and resc

104 indicated that soy protein with isoflavones lessened lumbar spine bone loss in midlife women.

105 all had reduced demyelination accompanied by lessened microglial and polydendrocyte cellular reactivi

106 A subtle intervention to lessen minority students' psychological threat related t

107 vailable, reducing violence in drug markets, lessening misuse of legal pharmaceuticals, preventing dr

108 wn of myosin IIA enhances cell spreading and lessens motility.

109 ng an inverse agonist of these receptors may lessen motor symptoms.

110 C5a receptor deficiency, which also lessens myeloid-derived suppressor cells in the premetas

111 cial distress in conjunction with efforts to lessen myocardial ischemia.

112 Erythropoietin (Epo) has potential to lessen neurologic sequelae due to hypoxia-ischemia.

113 ot be the best strategy for reducing pain or lessening neuronal degeneration because it also disrupts

114 ablative conditioning, with the exception of lessened nonrelapse mortality (hazard ratio, 0.50; P = .

115 tial task-related activation was followed by lessening of activation in prefrontal cortex, premotor c

116 y restored the WT phenotype, which suggested lessening of amino acid clashes in heterotetrameric chan

117 These defects reflect a true lessening of associative memory strength, as distortions

118 se in astrogliosis was also witnessed in the lessening of severity of EAE clinical scoring, indicatin

119 stration that SMN2 trans-splicing leads to a lessening of the severity of the SMA phenotype and provi

120 in the SHUV pigment is attributed to the (i) lessening of the steric restraints near the beta-ionone

121 IOL Master software version 5 upgrade should lessen operator variability and further enhance signal a

122 Although decision regret appears to lessen or dissipate with time, study on larger numbers o

123 eficial to the macaques, which in return may lessen or extinguish the remarkable foraging technology

124 nockdown of delta-opioid receptors (DOR) can lessen or prevent development of tolerance and dependenc

125 fect with a resultant diagnostic work-up can lessen or prevent tumor burden, improve screening for po

126 P retention might be lessened, or reversed, depending on the kinetics and siz

127 c patterns at broad scales; this interaction lessens our ability to confidently ascertain native vs.

128 to autoxidize in vitro did not substantially lessen overall H(2)O(2) formation.

129 e long been known to buffer ROS activity and lessen oxidative perturbations during exercise.

130 xidant defenses is an important mechanism to lessen oxidative stress and inflammation.

131 ted in significant increases in survival and lessened pathology.

132 t medium dose, the measured LBW protocol may lessen patient-to-patient enhancement variability while

133 tical as we attempt to better understand and lessen persistent child asthma disparities.

134 This lessened perturbations in expression of endothelial biol

135 ng Akt1 expression specifically in VSMCs may lessen plaque progression.

136 osclerosis throughout the vascular tree, and lessened plaque inflammation.

137 berry intake improved antioxidant status and lessened plasma interleukin (IL)-6 (0.3-fold of control,

138 as-phase conversion of large molecules while lessening possible memory effects.

139 Synergistic drug combinations can lessen potential toxic side effects through lower dosing

140 rs previously (RR 0.29), with risk reduction lessening progressively as the time since the last birth

141 eactive oxygen species with N-acetylcysteine lessened protein aggregation and decreased apoptosis, su

142 The intervention aimed to lessen psychological perceptions of threat on campus by

143 This finding was driven primarily by the lessened psychological value that more conservative indi

144 GSK3beta might serve as a unique strategy to lessen pulmonary inflammation.

145 ligases might serve as a unique strategy for lessening pulmonary inflammation.

146 nsitive interventions are being developed to lessen racial/ethnic health disparities.

147 lockade of the N- and L-type calcium channel lessens renal injury in kidney disease patients.

148 We speculate that this lessens repression of dpp dorsally, and thus creates a p

149 The lessened response after repeated exposure, likely driven

150 osure to noise could lead to a heightened or lessened response.

151 Tumor-associated edema and necrosis were lessened, resulting in increased perfusion and reduced d

152 ight be amenable to interventions that could lessen risks and help to prevent future child deaths.

153 once a diagnosis has been made, not only to lessen risks for comorbidities, but also to avoid aggrav

154 Melatonin supplementation has been shown to lessen SCI, but its use has been limited by its side eff

155 yramidal cells and interneurons considerably lessens seizure severity by decreasing cortical excitabi

156 eased the robustness of the oscillator, with lessened sensitivity to changes in cyclin synthesis rate

157 inhibitor targeting Fbxo3 was sufficient to lessen severity of cytokine-driven inflammation in sever

158 Vaccination can reduce illness and lessen severity of infection.

159 tant because many immunosuppressive regimens lessen severity.

160 However, although BICR lessens some potential biases, it does not remove all bi

161 gical causes increased treatment support and lessened stigma.

162 diminishes myelin basic protein abundance by lessening stimulation of the exchange protein directly a

163 This reduction lessened subsequently, to 0.18 mm(3), by month 9.

164 rojections of future climate change have not lessened substantially in past decades.

165 around the world to improve cancer care and lessen suffering for patients worldwide.

166 , a majority of fathers and mothers reported lessening suffering as the primary goal.

167 Parent disagreement about the goal of lessening suffering at the EOL appears to impact how par

168 parents did not agree on the primary goal of lessening suffering, both parents were more likely to re

169 Serving as decoys, receptor mimics may lessen symptoms while avoiding the use of antibiotics.

170 These pectin structural changes may lessen the ability of the cell wall to undergo stress re

171 c acid receptor antagonist (AGN193109) could lessen the anterior transformation phenotype and rescue

172 n, an impaired endothelial NO response could lessen the benefit of RAS inhibition in diabetic renal d

173 function presents an exciting opportunity to lessen the burden of disease in these patients.

174 t in developing accurate prediction tools to lessen the burden of experimental work and cope with the

175 more research is urgently needed in order to lessen the burden of macrovascular complications of type

176 interactions may lead to innovative ways to lessen the burden of this common childhood disease.

177 ovaries at doses greater than 5 Gy seems to lessen the carcinogenic effects of breast irradiation, m

178 It would also lessen the chances of exposing patients to treatments th

179 mes between such segments may be expected to lessen the chances of swapping events.

180 ancy-based ventilation have the potential to lessen the climate impact of surgical services without c

181 here is no effective treatment to prevent or lessen the consequences of neonatal H-I.

182 r encephalopathies of other etiologies-would lessen the controversy considerably, as the attribution

183 cle system provide a promising new avenue to lessen the debilitating motor symptoms of HD.

184 treatment of mice with established HF could lessen the detrimental phenotype associated with pressur

185 Here we explore ways to lessen the divide between LMICs and high-income countrie

186 , possibly mediated by hydrogen bonding, can lessen the effect of electrostatic repulsions.

187 elty and/or oral beta-adrenergic agonists to lessen the effects of Abeta accumulation during aging.

188 sistance are the two ways in which hosts can lessen the effects of infection.

189 Countermeasures that lessen the effects of unloading include physical activit

190 tumor response and frequently contributes to lessen the efficacy of immunotherapeutic approaches.

191 Additional resources were perceived to lessen the impact of lost earnings, help offset costs as

192 in C supplementation to pregnant smokers can lessen the impact of maternal smoking on offspring pulmo

193 pain, foot conditions and interventions that lessen the impact of rheumatic diseases.

194 nhibiting COX-2 during lactation weaning may lessen the incidence of breast cancer metastasis.

195 nterventions with translational potential to lessen the incidence of these deleterious immune respons

196 -5p may serve as a compensatory mechanism to lessen the increase in FGF9 and prevent aberrant lung de

197 ly, and consider the importance of timing to lessen the inherent risks of each procedure.

198 liver would increase hepcidin expression and lessen the iron loading in both models.

199 rence to evidence-based recommendations will lessen the morbidity and mortality associated with febri

200 ourse regimen has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, bu

201 ourse regimen has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, bu

202 These results do not lessen the need for further studies, continuous self-reg

203 e as a whole, these true 'genomic medicines' lessen the need for precision approaches to individualiz

204 ent blood management need to be developed to lessen the need for transfusion--eg, by early identifica

205 beetroot and beetroot juice, are reported to lessen the oxygen cost of exercise, increase efficiency,

206 atory T cells can be used therapeutically to lessen the pathogenicity of virus-specific immune cells

207 Reduced drug exposure might lessen the possibility of drug-related adverse events an

208 eptable by adopting risk-managed routes that lessen the potential to adversely impact high-quality gr

209 lacement of transgenes in the chloroplast to lessen the probability of 'escape' to weedy relatives ha

210 testing of each specimen may be advisable to lessen the probability of underestimating an individual

211 c and probiotic therapy has the potential to lessen the public health burden of antimicrobial-associa

212 erence, greater hip circumference appears to lessen the risk of diabetes and CHD.

213 than invasive biopsy is important as it will lessen the risk of infection and other stresses, while r

214 Presence of immune recovery may lessen the risk of postoperative ocular complications.

215 o therapeutic interventions are available to lessen the risk of the development of the haemolytic ura

216 xpayer dollars in biomedical research and to lessen the risk required for industry partners to make s

217 posure to bleaching in 1998 and 2002 did not lessen the severity of bleaching in 2016.

218 s, should it become achievable, would likely lessen the severity of nephrotic syndrome in patients ca

219 To lessen the severity of recurrent hepatitis C virus (HCV)

220 gies to control the USA300 SSTI epidemic may lessen the severity of the concurrent USA300 BSI epidemi

221 ay negatively regulate VSMC proliferation to lessen the severity of the lesion.

222 ough associated with larger economic losses, lessen the social-psychological impact of job loss.

223 s to California's flammability standards may lessen the use of other flame retardants and similarly r

224 ound C or AMP-activated protein kinase siRNA lessened the activation of Jun N-terminal kinase, extrac

225 s well as antibody incubations significantly lessened the background compared with including only the

226 e JAK1/2 inhibitor ruxolitinib significantly lessened the clinical and laboratory manifestations of H

227 3T3-L1 adipocytes, knockdown of PFKFB3/iPFK2 lessened the effect of PPARgamma activation on stimulati

228 red to far-red ratio, unlike cold treatment, lessened the effects of FLC despite continued FLC expres

229 The exogenous GSH treatment clearly lessened the HT stress by increasing the above variables

230 and mineralocorticoids neither augmented nor lessened the hypertrophic response.

231 vide pain relief (over avoid analgesic risk) lessened the likelihood that parents would withhold the

232 , transplantation of WT BM into N1(+/-) mice lessened the myocardial injury observed in N1(+/-) mice.

233 Medication then reduced symptoms and lessened the need for compensation, thereby normalizing

234 50%, decreased the number of dying neurons, lessened the number of activated microglial cells, prote

235 ween GPIbalpha and GPIbbeta subunits further lessened the restraint of GPIbbeta on GPIbalpha shedding

236 ptotic and inflammatory effects of IL-33 and lessened the severity of lung injury in mouse models of

237 h a reactive oxygen species scavenger, which lessened the severity of the blood phenotype.

238 The Fbxo3 inhibitors effectively lessened the severity of viral pneumonia, septic shock,

239 Endotoxemia lessened the tyramine-induced reduction in leg vascular

240 ofessional oncology society, is committed to lessening the burden of cancer and as such will promote

241 ncer disparities is critically important for lessening the burden of cancer.

242 , promiscuous self-assembly may be possible, lessening the dependence on a particular set of oligomer

243 rs2294918 E434K decreased PNPLA3 expression, lessening the effect of the I148M variant on the predisp

244 otransmitter release in presynaptic neurons, lessening the effects of demyelination.

245 nded to allow new mutations to accumulate by lessening the effects of purifying selection through the

246 intestinal mucosal inflammation, potentially lessening the extent and severity of injury.

247 naturally occurring reactive metals, thereby lessening the impacts of matrix diffusion on sustaining

248 y be an effective treatment in inhibiting or lessening the inflammatory response mediated through TLR

249 rden of HZ; and to discuss the challenges of lessening the morbidity of the disease.

250 odeling as a triage point at the laboratory, lessening the need for laboratory-based CD4(+) T cell co

251 preoperatively continues to be important in lessening the risk of postoperative inflammation and com

252 ed FBXL2 actions by stabilizing CCTalpha and lessening the severity of inflammatory lung injury.

253 Lessening the structural ambiguity would lead to further

254 e the fracture resistance of lithiated Si by lessening the tensile stress concentrations in Si struct

255 ous modified dosing regimens with the aim of lessening the treatment burden associated with monthly i

256 ous modified dosing regimens with the aim of lessening the treatment burden associated with monthly i

257 erica serovar Typhimurium PhoQ sensor kinase lessens the cytotoxicity of reactive nitrogen species (R

258 Stable knockdown of elevated SENP7L levels lessens the dissemination of highly metastatic BCa cells

259 bly due to a hostile host brain environment, lessens the effectiveness of this approach.

260 orelimb (NPT) following a unilateral infarct lessens the efficacy of rehabilitative training, and red

261 s the robustness of the progenitor state and lessens the impact of unequal, random distribution of mo

262 -yl)-1,2,4-thiadiazolidine-3,5-dione (NP12), lessens the magnitude of adverse myocardial remodeling a

263 motes anorexia and that PACAP preferentially lessens the maintenance of feeding in rats, effects oppo

264 ated with education or vocabulary knowledge) lessens the negative impact of brain disease on cognitio

265 Inhibiting this self-propagating pathway lessens the overall inflammatory burden, which may alter

266 tamin D/high-calcium (2%)/lactose (20%) diet lessens the phenotype, and knockout pups fostered to mot

267 a sufficient dose reaches the target tissue, lessens the potential for off-target side effects, and c

268 sociation of toluene with the catalyst which lessens the relative importance of the uncatalyzed backg

269 iconductor-insulator-metal interface greatly lessens the scattering loss, and more importantly, effic

270 hemoglobin (HbF, alpha(2)gamma(2)) in adults lessens the severity of sickle cell disease (SCD) and th

271 ratrol treatment of mice with established HF lessens the severity of the HF phenotype by lessening ca

272 ebral-ventricular space in SMA neonates also lessens the severity of the SMA phenotype in a severe SM

273 arents who exercise good smoking hygiene can lessen their child's risk of developing plaque.

274 rmation, whereas numbers needed to treat can lessen their understanding.

275 d support from local leaders, which may have lessened their success.

276 ces for promotion and tenure, and ultimately lessening their own job security and feeling of accompli

277 ntensive perioperative steroid treatment can lessen these complications.

278 riate devices and supporting services) might lessen these concerns.

279 To lessen these effects, we have encapsulated an anti-cance

280 rs, because the Rho inhibitor C3 transferase lessened these effects.

281 Prior experience in adult day care may lessen this association.

282 ontinuation of immunosuppressive drugs could lessen this burden, but the safety, applicability, and c

283 ant that cannot translocate within dendrites lessened this activity-dependent synaptic plasticity.

284 HIT and identifies potential new targets for lessening this risk.

285 nal damage and the use of blue-blocking IOLs lessens this damage.

286 PA, attenuated ICH, lowered plasma d-dimers, lessened thrombocytopenia, and improved neurologic outco

287 activities, biweekly treatment with NPI-0052 lessened total white blood cell (WBC) burden over 35 day

288 Although this difference lessened toward term, overall, mothers of maternally inh

289 ighlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibili

290 ss in obese men and dietary modification can lessen urgency, nocturia, and incontinence.

291 es during warm seasons, which is removal and lessening versus enhancement of air pollution.

292 activity levels through young adulthood may lessen weight gain as young adults transition to middle

293 t different subtypes of influenza viruses by lessening weight loss and lowering viral loads.

294 This tedious and time-consuming work can be lessened with automatic Question Answering (QA) systems,

295 trade-offs are expected to be significantly lessened with CNF manufacturing maturity.

296 th dexmedetomidine but the occurrence may be lessened with low dose.

297 These limitations might be lessened with next-generation RNA sequencing (RNA-seq).

298 uence of predisposing factors for second AMI lessened with time after the initial event.

299 In patients, muscle stiffness lessens with exercise, a change known as the warmup phen

300 using us to speculate that T-cell activation lessens with time.