ライフサイエンスコーパス: lethal gene

1 ied in a recent screen for A. aegypti larval lethal genes.

2 can be used to uncover neuronal defects for lethal genes.

3 tations reveals a group of 130 synthetically lethal genes.

4 ss likely to be disease genes than postnatal lethal genes.

5 are also discussed relative to other hybrid lethal genes.

6 years, identifying perhaps 250-350 embryonic lethal genes.

7 cterium-phage combination, given a universal lethal gene and an inducible promoter which is triggered

8 erference screen to search for Myc-synthetic lethal genes and uncovered a role for the SUMO-activatin

9 s of "conserved, essential" and "young, RNAi-lethal" genes and broadly confirmed the lethality of the

10 to the two RBDs found in the Drosophila sex-lethal gene are each encoded in two exons, whereas the t

11 strains (TSS) that carry conditional female lethal genes are advantageous for genetic control progra

12 -acting factors encoded by the male-specific lethal genes are required for this process.

13 achine learning methods that predicted known lethal genes as well as an additional 1970 likely essent

14 ting engineered constructs that both carry a lethal gene, but suppress each other.

15 n of cells by the controlled expression of a lethal gene can be used to engineer plant traits such as

16 s designated as NTL T-DNA vectors (non-T-DNA lethal gene-containing T-DNA vectors).

17 0 knockout mouse lines, here we identify 410 lethal genes during the production of the first 1,751 un

18 Programmable transcription factors drive lethal gene expression in hybrid offspring following und

19 ciency analysis places the locus between the lethal genes extra organs (eo) and lethal B20 (lB20).

20 pplications such as extracting synthetically lethal genes from the cancer literature.

21 instance the identification of synthetically lethal genes from the literature.

22 A detailed examination of the Drosophila Sex-lethal gene has led to two significant discoveries-the r

23 One histone synthetic-lethal gene, HSL1, encodes a putative protein kinase tha

24 n of Wilms tumor 1 (Wt1) as a Kras synthetic-lethal gene in a mouse model of lung adenocarcinoma.

25 We identify BUD31 as a MYC-synthetic lethal gene in human mammary epithelial cells, and demon

26 yme and potential use as a novel conditional lethal gene in plants are discussed.

27 the pehA gene as a heterologous conditional lethal gene in plants is discussed.

28 ability for our reference list of synthetic lethal gene interactions (R = 0.159).

29 cumulation of mutations can expose synthetic lethal gene interactions and oncogene-driven cellular re

30 The lethal gene of the suicide system consists of the three-

31 ows characterization of effects of recessive lethal genes on adult phenotypes and here enabled identi

32 e contains approximately 3479-4825 embryonic lethal genes, or about 13.7%-19% of all genes.

33 ried out novel predictions of synthetic sick/lethal gene pairs at a genome-wide scale.

34 on networks are available and synthetic sick/lethal gene pairs have been extensively identified.

35 those that characterize the known synthetic lethal gene pairs.

36 Among the strongest synthetic lethal genes, polarity defects are more apparent in par-

37 ypes after RNA interference of 147 embryonic lethal genes previously identified in a systematic scree

38 anscription factor to regulate a selectively lethal gene product.

39 n mosquitoes carrying a conditional dominant lethal gene (release of insects carrying a dominant leth

40 ty, and, in association with a conditionally lethal gene (SacB) permit efficient, high-fidelity trans

41 These results represent the first report of lethal gene silencing in Schistosoma.

42 The paternal-effect embryonic-lethal gene, spe-11, is required for normal development

43 Transmission of lethal genes such as associated with Huntington's diseas

44 both; the release of Aedes carrying dominant lethal genes, such as the OX513A strain of A. aegypti; a

45 for a dominant, repressible, female-specific lethal gene system are used.

46 of transgenic mosquitoes harboring dominant lethal genes, the introduction of arbovirus-blocking mic

47 Interestingly, embryonic lethal genes, the most essential genes in mouse, were le

48 ranzymes A and B also survived the otherwise lethal gene transfer.

49 t included use of sterile males, conditional lethal genes, translocations, compound chromosomes, and

50 The lethal gene used here is a CaMV 35S-barnase gene with an

51 ase was evaluated in plants as a conditional lethal gene useful for cell ablation and negative select

52 A lethal gene was incorporated into the non-T-DNA portion

53 te that the B. subtilis skin element carries lethal genes, which are induced by the depletion of sknR