ライフサイエンスコーパス: leucine

1 th a 9-hour primed constant infusion of 13C6-leucine.

2 tivity but can also cleave efficiently after leucine.

3 nce of Val or Ile but not in the presence of leucine.

4 rystal structure of Sestrin2 in complex with leucine.

5 ines and glycines, and negative selection of leucines.

6 Leucine-10g, but not leucine-5g, increased plasma insuli

7 g mutations, which result in substitution of leucine-115 with an arginine (L115R) or deletion of the

8 nine (L115R) or deletion of the neighbouring leucine-116 (L116) in the cysteine-string domain cause C

9 raise important questions about the role of leucine 138 in supporting key protein interactions and t

10 OsMTP11 harbouring a substitution of leucine 150 to a serine fully rescued pmr1 Mn-sensitivit

11 stituting the ubiquitously conserved residue leucine 29 to alanine in the pore-forming region increas

12 ine (57.6%), phenylalanine+tyrosine (32.6%), leucine (45.7%) and isoleucine (68%) are found less in h

13 how that polymer nanoparticles encapsulating leucine(5)-enkephalin hydrochloride (LENK) are able to t

14 Leucine-10g, but not leucine-5g, increased plasma insulin and C-peptide AUCs

15 untamine-140 at the (137)P-X-P-X(140) motif, leucine-66, proline-67, and asparagine-176 may account f

16 Strikingly, replacement of leucine(973) in the juxtamembrane region of IR to phenyl

17 orlaudanosine with 1 equiv of (-)-N-acetyl-l-leucine afforded the leucinate salt (+)-13 (99:1 dr).

18 n markedly extend CWD latency when the minor leucine allele (132L) is present.

19 Exogenous leucine also inhibits Lrp-mediated tos operon positive r

20 ate that ultrafast reorientation dynamics of leucine amino acids at interfaces can be recorded in sit

21 antibody against a hepatic surface protein, leucine amino peptidase (LAP).

22 pathways: beta-alanine; valine, leucine, iso-leucine; aminoacyl-tRNA; and alanine, aspartate, glutama

23 -1-carboxylic acid ((18)F-fluciclovine) is a leucine analog radiotracer that depicts amino acid trans

24 We identify ERG240 as a leucine analogue that blocks BCAT1 activity.

25 stribution and uptake of three (18)F-labeled leucine analogues via LAT1 mediated transport in several

26 Previous analysis of leucine and alanine substitutions at the Val-65-equivale

27 se results suggest that multiple patterns of leucine and arginine can support spontaneous membrane tr

28 ructure of two protected amino acids, FMOC-l-leucine and FMOC-l-valine, and a dipeptide, N-acetyl-l-v

29 smembrane proteins consisting exclusively of leucine and isoleucine (called LIL traptamers) that spec

30 In healthy subjects, both leucine and isoleucine reduced blood glucose in response

31 of all hypothetical isomer pairs, including leucine and isoleucine, whereas their stereoisomers (d-

32 uding baseline resolution of isomers such as leucine and isoleucine.

33 c plants such as aspartate, lysine, glycine, leucine and threonine with no changes in the amounts of

34 Both leucine and TSC1 deletion blocked nesfatin-1-induced up-

35 We found that isoleucine, leucine and tyrosine levels were significantly higher in

36 cine levels and one SNP associated with both leucine and valine levels at genome-wide significance.

37 ding branched chain amino acids (isoleucine, leucine and valine) that have been identified previously

38 set of aliphatic side chains such as valine, leucine, and isoleucine of putative substrates.

39 reased storage reserves, elevated valine and leucine, and reduced germination rates.

40 f the branched-chain amino acids isoleucine, leucine, and valine are associated with Alzheimer's dise

41 for the resolution of the BCAAs isoleucine, leucine, and valine, as well as 13 other amino acids, in

42 D) were 400, 200, and 100 nM for isoleucine, leucine, and valine, respectively.

43 The leucine- and valine-raising allele was not associated wi

44 orporates the methionine surrogate azido-nor-leucine (ANL) into newly generated proteins.

45 gh they, like the three B69 isolates, have a leucine at position 226 in the hemagglutinin (HA) recept

46 equence variant, causing the substitution of leucine at position 752 to phenylalanine, in PLAA, which

47 /- 2%), with no difference in whole-body net leucine balance (P = 0.27).

48 Whole-body fluxes of leucine, before and after the meal, were determined with

49 We find that leucine, but not arginine, disrupts the Sestrin2-GATOR2

50 leucine) and seed development was limited to leucine catabolism.

51 is known to be involved in drug binding, the leucine cluster region of betaIII-tubulin contains a uni

52 Leucine co-ingestion with lower-protein (LP)-containing

53 We examined the impact of leucine co-ingestion with mixed macronutrient meals on i

54 we create a Salmonella with 1557 synonymous leucine codon replacements across 176 genes, the largest

55 A major ribosome pause at CTC leucine codons in the native gene of FVIII HC was elimin

56 tion constant of 20 micromolar, which is the leucine concentration that half-maximally activates mTOR

57 Plasma leucine concentrations and exogenous phenylalanine appea

58 using peptide libraries that substituted its leucine core with each natural amino acid.

59 We found that leucine, cysteine and tryptophan are inserted during W12

60 Ingestion of protein, but not leucine, decreased insulin-stimulated glucose disposal (

61 We identified compounds that inhibit the leucine-dependent mTORC1 pathway by specifically inhibit

62 een carried out in the presence of an l-tert-leucine-derived squaramide as organocatalyst.

63 combinant ALD1 transaminates l-methionine, l-leucine, diaminopimelate, and several other amino acids

64 ed protonated C-terminally methyl esterified leucine enkephalin [YGGFL-OMe+H](+).

65 s highlighted the importance of a C-terminal leucine for function.

66 encing a homozygous missense substitution of leucine for serine at codon 31 in ZNHIT3 was identified

67 tudied using a stable isotope infusion of D3-leucine, gas chromatography/mass spectrometry, and multi

68 SLC38A9 is necessary for leucine generated via lysosomal proteolysis to exit lyso

69 even of those polar metabolites (L-serine, L-leucine, glucose, fructose, myo-inositol, citric acid an

70 s depletion decreased incorporation of [(3)H]leucine in K-Ras-expressing cells, suggesting that Golgi

71 ity is associated lower serum isoleucine and leucine in peripubertal girls, independent of BMI, which

72 ske domain and substitution of tyrosine with leucine in the mononuclear iron center differentiate oxy

73 acids (P < 0.01), a lower entry rate of meat leucine in the plasma (P < 0.01), and a lower contributi

74 nt partition coefficients (phenylalanine and leucine) in emulsions.

75 l-[ring-(2)H5]-phenylalanine and l-[1-(13)C]-leucine infusions and ingested 25 g intrinsically l-[1-(

76 s l-[ring-(2)H5]phenylalanine and l-[1-(13)C]leucine infusions and performed a single bout of resista

77 Neither protein nor leucine ingestion altered plasma adiponectin or NEFA con

78 ound that during the HECP without protein or leucine ingestion, the grand mean +/- SEM plasma 3-HIB c

79 h RM than with FCM (40% compared with 56% of leucine intake, respectively; P < 0.01).Whereas meat coo

80 l amino acid, branched-chain amino acid, and leucine intakes are associated with improved survival an

81 , were determined with the use of a [1-(13)C]leucine intravenous infusion.

82 Leucine is of particular importance and activates mTORC1

83 r metabolism pathways: beta-alanine; valine, leucine, iso-leucine; aminoacyl-tRNA; and alanine, aspar

84 on of the branched-chain amino acids (BCAAs) leucine, isoleucine (Ile), and valine (Val) in the mitoc

85 Branched-chain amino acids (BCAAs; leucine, isoleucine and valine) are elevated in the bloo

86 hways for biosynthesis of histidine, valine, leucine, isoleucine, lysine and proline pre-determines t

87 The serum levels of valine, leucine, isoleucine, tyrosine, and phenylalanine were me

88 he highest levels of glucose at 120 min, and leucine, isoleucine, valine and proline at 90 and 120 mi

89 (alanine, glycine, histidine, phenylalanine, leucine, isoleucine, valine, and tyrosine) were assessed

90 a virus F TM domain revealed a heptad repeat leucine-isoleucine zipper motif (LIZ).

91 els of the branched chain amino acids (BCAs) leucine/isoleucine and their deaminated metabolites, and

92 m amino acid signature composed of arginine, leucine/isoleucine, phenylalanine, tyrosine, valine and

93 samples were collected to assess whole-body leucine kinetics, intramuscular signaling, and myofibril

94 In this process, E6 binds to a short leucine (L)-rich LxxLL consensus sequence within the cel

95 y l-[1-(13)C]-phenylalanine- and l-[1-(13)C]-leucine-labeled whey protein.

96 ipants consumed intrinsically l-[5,5,5-(2)H3]leucine-labeled whole eggs (18 g protein, 17 g fat) or e

97 e discrimination of isobaric residues (Xle): leucine (Leu) and isoleucine (Ile).

98 e have found a new potent activator, benzoyl-leucine-leucine (Bz-LL), that binds with higher affinity

99 In addition, isoleucine and leucine levels increased significantly ( 15%) from child

100 e NMR to specifically characterize the bound leucine ligand and probe the number of binding sites in

101 the necessity of unsubstituted triazoles and leucine linker to obtain maximal growth inhibition of th

102 S/MS), called mass defect-based N,N-dimethyl leucine (mdDiLeu) labeling.

103 nds, combinatorially perturbed in histidine, leucine, methionine and uracil biosynthesis.

104 lerated including those for alanine, valine, leucine, methionine, lysine, phenylalanine, tyrosine, an

105 Arginine, lysine, isoleucine, leucine, methionine, phenylalanine, valine, GABA, glutam

106 d a cell permeant fluorescent analogue of di-leucine methyl ester.

107 ntal conditions there is only one detectable leucine molecule bound to LeuT.

108 -valine, and a dipeptide, N-acetyl-l-valyl-l-leucine (N-Ac-VL), were studied via one- and two-dimensi

109 ngthening of lifetimes required two specific leucines on the C-terminal tail of microR.

110 sures, and branched-chain amino acids (e.g., leucine OR = 2.94, 2.51-3.44).

111 for C932R, whereas replacement of C932 with leucine or phenylalanine, the latter of a size comparabl

112 Total plasma availability of leucine over the 300-min postprandial period was similar

113 Mutation of the invariant proline to leucine (P838L) caused dominant restrictive cardiomyopat

114 Leucine protected knee extensor peak torque (CON compare

115 position 10 amino acid from phenylalanine to leucine, reduces protein expression by approximately hal

116 imerization and that mutation of a conserved leucine residue abolishes self-association.

117 associating protein with a high frequency of leucine residues (Daple) interacts with PCP and cell-int

118 modified these trimer designs by introducing leucine residues at V3 positions 306 and 308 to create h

119 ly, we investigated the methyl groups of two leucine residues that belong to the hydrophobic core (L1

120 cally, the introduction of helix-stabilizing leucine residues within the TMD region spanning the vesi

121 butions from conserved aromatic, acidic, and leucine residues.

122 Leucine restriction (LR) replicates some, but not all, o

123 delity, but replacements with isoleucine and leucine resulted in lower-fidelity phenotypes.

124 Lumican, a small leucine rich proteoglycan (SLRP), is a component of extr

125 Decorin (DCN) is a small-leucine rich proteoglycan that mediates collagen fibrill

126 The cytosolic nucleotide binding site-leucine rich repeat (NBS-LRR) resistance proteins of pla

127 s nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 (NLRP1

128 d rate of enamel regeneration and the use of leucine-rich amelogenin peptide (LRAP), a nonphosphoryla

129 ibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP).

130 The leucine-rich G protein-coupled receptor-5 (LGR5) is expr

131 d potassium channel (VGKC) complex proteins, leucine-rich glioma-inactivated 1 (LGI1) and contactin-a

132 s, which target the extracellular domains of leucine-rich glioma-inactivated 1 (LGI1) and contactin-a

133 auditory features results from mutations in leucine-rich glioma-inactivated 1 (LGI1), a soluble glyc

134 potassium channel-complex related proteins (leucine-rich glioma-inactivated 1 and contactin-associat

135 iallelic loss-of-function mutations in LGI4 (leucine-rich glioma-inactivated 4).

136 0.7%) had VGKCc (4 of whom were positive for leucine-rich glioma-inactivated protein 1 [LGI1] Ab), an

137 Leucine-rich glioma-inactivated1 (LGI1) encephalitis is

138 cts with several short motifs, named helical leucine-rich motifs (HLMs), spread in the long C-termina

139 y through the activity of Rev's prototypical leucine-rich nuclear export signal (NES).

140 Prp40 possesses two leucine-rich nuclear export signals, but little is known

141 Here, we found that Drosophila leucine-rich pentatricopeptide repeat domain-containing

142 n as candidate substrates of mOGT, including leucine-rich PPR-containing protein and mitochondrial ac

143 smic localization of proline, glutamic acid, leucine-rich protein 1 (PELP1) is observed in approximat

144 Decorin, an archetypical small leucine-rich proteoglycan, initiates a protracted autoph

145 most N-terminal domain of Reck binds to the leucine-rich repeat (LRR) and immunoglobulin (Ig) domain

146 is repressed by a flanking substrate-binding leucine-rich repeat (LRR) domain when substrate is absen

147 CCR4s contain N-terminal leucine-rich repeat (LRR) motifs that interact with CAF1

148 mutants encodes a receptor lacking a single leucine-rich repeat (LRR) within its N-terminus.

149 his study, we identified LRRC25, a member of leucine-rich repeat (LRR)-containing protein family, as

150 eotide-binding (NB) domain, and a C-terminal leucine-rich repeat (LRR).

151 ition of XopQ 1 (Roq1), a nucleotide-binding leucine-rich repeat (NLR) protein with a Toll-like inter

152 ical to VICTR, encoding a nucleotide-binding leucine-rich repeat (NLR) protein(3).

153 Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable the immune sys

154 Nucleotide-binding domain leucine-rich repeat (NLR) proteins function as cytosolic

155 ted by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins.

156 OUS MIX2 (DM2) nucleotide-binding domain and leucine-rich repeat (NLR)-encoding locus in A. thaliana.

157 We previously demonstrated that leucine-rich repeat and Ig-like domain-containing Nogo r

158 Leucine-rich repeat and Ig-like domain-containing Nogo r

159 d nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NRLP3

160 ng and oligomerization domain-like receptor, leucine-rich repeat and pyrin domain-containing 3 (NLRP3

161 nase kinases (MKKs) and rodent NLRP1B (NACHT leucine-rich repeat and pyrin domain-containing protein

162 nical events except stroke, the LRRC3B gene (leucine-rich repeat containing 3B) with myocardial infar

163 Leucine-rich repeat containing 8A (LRRC8A) is an ubiquit

164 Leucine-rich repeat containing G-protein-coupled recepto

165 tly characterized nucleotide-binding domain, leucine-rich repeat containing protein (NLR) that negati

166 Here, we report that leucine-rich repeat containing protein 25 (LRRC25) is a

167 re the role of the nucleotide-binding domain leucine-rich repeat containing receptor family member Nl

168 he role of the nucleotide-binding domain and leucine-rich repeat containing receptor NLRP10 in diseas

169 Scribble consists of a leucine-rich repeat domain and four PDZ domains, with th

170 The tyrosine-sulfated domain and the leucine-rich repeat domain both bound to three specific

171 domain gene product containing an N-terminal leucine-rich repeat domain, followed by a likely posttra

172 e plant can evolve nucleotide-binding domain-leucine-rich repeat domain-containing proteins to recogn

173 Moreover, the leucine-rich repeat domains, and specifically four amino

174 We show that Drosophila leucine-rich repeat G protein-coupled receptor 3 (Lgr3)

175 Mutations in leucine-rich repeat kinase 2 (LRRK2) and alpha-synuclein

176 Mutations in leucine-rich repeat kinase 2 (LRRK2) are associated with

177 Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common

178 Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common

179 Mutations in leucine-rich repeat kinase 2 (LRRK2) contribute to devel

180 Genetic variation in the leucine-rich repeat kinase 2 (LRRK2) gene is associated

181 Leucine-rich repeat kinase 2 (LRRK2) is a large, multido

182 Mutations in leucine-rich repeat kinase 2 (LRRK2) lead to late-onset,

183 unknown, but several genetic loci, including leucine-rich repeat kinase 2 (LRRK2), have been identifi

184 Mutations in leucine-rich repeat kinase 2 (LRRK2), such as G2019S, ar

185 r matrix component proline/arginine-rich end leucine-rich repeat protein (PRELP) is a novel antibacte

186 he EMT inducer Twist1 by enhancing F-box and leucine-rich repeat protein 14 (FBXL14)-mediated polyubi

187 Here, we show that Fbxl17 (F-box and leucine-rich repeat protein 17) targets Sufu for proteol

188 is capable of triggering NLRP3 (NLR-family, leucine-rich repeat protein 3) inflammasome activation a

189 usly unrecognized role for the transmembrane leucine-rich repeat protein Lapsyn in regulating mng dev

190 We show that the phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP) downstre

191 n this study, we demonstrated that PH domain leucine-rich repeat protein phosphatase (PHLPP), a novel

192 we identified pleckstrin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) as a

193 1.2 encodes a coiled-coil nucleotide-binding leucine-rich repeat protein that in addition to potato a

194 rice gene Xa1, encoding a nucleotide-binding leucine-rich repeat protein, confers resistance against

195 c map of the entire folding landscape of the leucine-rich repeat protein, pp32 (Anp32), obtained by c

196 Nucleotide binding domain and leucine-rich repeat proteins (NLRs) are important recept

197 enes encoding coiled-coil nucleotide-binding leucine-rich repeat proteins designated CNL3 and CNL13.

198 and activate the nucleotide-binding domain, leucine-rich repeat pyrin domain-containing 3 (NLRP3) in

199 by direct binding to the membrane-localized leucine-rich repeat receptor kinases, PEP RECEPTOR1 (PEP

200 roid insensitive 1 (BRI1) is a member of the leucine-rich repeat receptor-like kinase family.

201 Cell signaling pathways mediated by leucine-rich repeat receptor-like kinases (LRR-RLKs) are

202 i, including proteins putatively involved in leucine-rich repeat recognition activity, second messeng

203 Nucleotide-binding site leucine-rich repeat resistance genes (NLRs) allow plants

204 ike mechanism that employs flanking variable leucine-rich repeat sequences as templates in associatio

205 PR library targeting the immunity-associated leucine-rich repeat subfamily XII genes, heritable mutat

206 rs designated "nucleotide-binding domain and leucine-rich repeat" (NLR) proteins that translate patho

207 LAT); B-cell CLL/lymphoma 11B (BCL11B); RGD, leucine-rich repeat, tropomodulin domain, and proline-ri

208 In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, apoptosis inhibit

209 IPs) activate the nucleotide-binding domain, leucine-rich repeat-containing family, CARD domain-conta

210 , we report a pivotal role for the R-spondin/leucine-rich repeat-containing G protein-coupled recepto

211 rkers, epithelial cell adhesion molecule and leucine-rich repeat-containing G protein-coupled recepto

212 Leucine-rich repeat-containing G protein-coupled recepto

213 Here we show that the leucine-rich repeat-containing G-protein-coupled recepto

214 Herein we report that leucine-rich repeat-containing G-protein-coupled recepto

215 The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, freque

216 o the B-family (or secretin-like), and 2 are leucine-rich repeat-containing GPCRs.

217 are sensed by nucleotide binding domain and leucine-rich repeat-containing proteins (NLRs), which tr

218 eotide-binding oligomerization domain (Nod), leucine-rich repeat-containing receptors (NLRs), and pyr

219 es with pyrin and nucleotide-binding domain, leucine-rich repeat/pyrin domain-containing 3.

220 scaffold protein composed almost entirely by leucine-rich repeats (LRRs) and having an N-terminal reg

221 c screen for genes encoding proteins bearing leucine-rich repeats (LRRs) and nucleotide-binding domai

222 usly expressed transmembrane protein with 17 leucine-rich repeats (LRRs) at its C-terminal end and is

223 (CITA), NLRC5 [nucleotide-binding domain and leucine-rich repeats containing (NLR) family, caspase ac

224 hocyte receptors (VLRs) composed of variable leucine-rich repeats, which are differentially expressed

225 ng on the NLRX1 (nucleotide-binding, lots of leucine-rich repeats-containing protein member X1)-TUFM

226 ibited by intramolecular binding to the Vms1 leucine-rich sequence (LRS).

227 also found that Lys-714 was located within a leucine-rich stretch, which resembles a nuclear export s

228 Here, we determined that fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsiv

229 Limbic encephalitis with leucine-rich, glioma-inactivated 1 (LGI1) antibodies is

230 the activation of nucleotide binding domain, leucine-rich-containing family, pyrin domain containing

231 ique among the nucleotide-binding-domain and leucine-rich-repeat (NLR) proteins in its mitochondrial

232 tf13, defining it as an F-box protein of the leucine-rich-repeat family, and demonstrates how a novel

233 s in the expansion of nucleotide-binding and leucine-rich-repeat proteins (NLRs), the major disease-r

234 Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell

235 st these factors using mutant LRRK2(R1441G) (leucine-rich-repeat-kinase-2) knockin mice.

236 Here, we demonstrate that the leucine sensor function for mTORC1 activation of LRS can

237 catalytic activity, and demonstrate that the leucine sensor function of LRS can be a new target for m

238 RNA synthetase (LRS) is known to function as leucine sensor in the mammalian target of rapamycin comp

239 mutations.Leucyl-tRNA synthetase (LRS) is a leucine sensor of the mTORC1 pathway.

240 Sestrin2 interacts with GATOR2 and is a leucine sensor.

241 d monosulfate 2, uridine, and gamma-glutamyl-leucine, showed independent associations with all-cause

242 liminates intramembrane proteolysis, as does leucine substitution of residues that overlap or are imm

243 report that methionine substitution, but not leucine substitution, results in increased open state st

244 s of both valine-to-methionine and valine-to-leucine substitutions at this position in both Kir6.1 an

245 Leucine supplementation may partially protect muscle hea

246 ivation of the mTOR pathway in response to L-leucine supplementation was retained, suggesting a possi

247 il domains through introduction of the bulky leucine surrogate homoisoleucine.

248 ngestion of protein (n = 15) or an amount of leucine that matched the amount of protein (n = 15).

249 f branched-chain amino acids (BCAA), such as leucine, thereby providing macromolecule precursors; how

250 s a novel point mutation in Btr1, changing a leucine to a proline in the protein product.

251 e show that A. pernix undergoes constitutive leucine to methionine mistranslation at low growth tempe

252 .305T>C alteration in exon 3, which causes a leucine to serine substitution at codon 102 (Human Genom

253 Mutation of these leucines to alanines decreased the magnitude of arrestin

254 addition of reaction precursors (glucose and leucine) to follow Maillard and caramelization reactions

255 Previously, a SCA5 mutation resulting in a leucine-to-proline substitution (L253P) in the actin-bin

256 ite, with a preference for lysine, arginine, leucine, tyrosine, and phenylalanine residues.

257 ched-chain amino acid degradation (named for leucine, valine and isoleucine) and seed development was

258 em proteins with stable isotopically labeled leucine was performed, and kinetics of Abeta40 and Abeta

259 s.Plasma appearance rates of protein-derived leucine were more rapid after the consumption of egg whi

260 , glutamate, isoleucine, and valine, but not leucine, were increased in NAFLD-NO subjects compared to

261 Mutation of talin2 S339 to leucine, which can cause Fifth Finger Camptodactyly, a h

262 tial amino acids out of lysosomes, including leucine, which mTORC1 senses through the cytosolic Sestr

263 on factor (MITF) is a basic helix-loop-helix leucine zipper (bHLH-Zip) DNA-binding protein.

264 components identified to date, HY5, a basic leucine zipper (bZIP) transcription factor, has been inv

265 elease a cytosolic domain containing a basic leucine zipper (bZIP) transcriptional activator.

266 n at serine 211 and expression of GC-induced leucine zipper (GILZ) were significantly reduced in ASM

267 The gamma-clade of class I homeodomain-leucine zipper (HD-Zip I) transcription factors (TFs) co

268 uxin levels activating class III homeodomain leucine zipper (HD-ZIP III) transcription factors (TFs).

269 ow that scaffold assembly requires conserved leucine zipper (LZ) and Cnn-motif 2 (CM2) domains that c

270 -terminal coiled-coil domain (CC) and/or the leucine zipper (LZ) domain of the myosin light-chain pho

271 osphotyrosine interacting with PH domain and leucine zipper 1 (APPL1) signaling endosomes and MYO6+ e

272 a regulatory pathway in which spermatogenic leucine zipper 1 (SPZ1) promotes EMT through its transac

273 he DNA binding activity of protagonist basic leucine zipper 53 (bZIP53) transcription factor and its

274 ent of a full-length myosin-X construct with leucine zipper at the C-terminal end of the tail (M10(Fu

275 After vaccination, both migratory basic leucine zipper ATF-like transcription factor 3 (BatF3)-d

276 ranscription factors in hematopoiesis is the leucine zipper CCAAT-enhancer binding protein alpha (C/E

277 VCCs when the NC domain was replaced with a leucine zipper dimerization motif that promotes Gag mult

278 lish SiMPull in plants using the HOMEODOMAIN LEUCINE ZIPPER III (HD-ZIPIII) and LITTLE ZIPPER (ZPR) i

279 ronal stress response controlled by the Dual Leucine Zipper Kinase (DLK) and contributes to DLK-media

280 Dual leucine zipper kinase (DLK) has been implicated in cell

281 Dual leucine zipper kinase (DLK) is required for stress-induc

282 The dual leucine zipper kinase (DLK)/c-Jun-N-terminal kinase (JNK

283 on is only partially protective, we identify leucine zipper kinase (LZK) as cooperating with DLK to a

284 The Maternal Embryonic Leucine Zipper Kinase (MELK) has been reported to be a g

285 ment of a novel selective maternal embryonic leucine zipper kinase (MELK) inhibitor HTH-01-091, CRISP

286 The protein kinase maternal and embryonic leucine zipper kinase (MELK) is critical for mitotic pro

287 se selectivity of type II maternal embryonic leucine zipper kinase inhibitors by applying these two c

288 that an evolutionarily conserved, truncated leucine zipper motif near the N terminus as well as a st

289 e transcription of three related Homeodomain leucine zipper protein (HD-ZIP)-encoding genes: HOMEOBOX

290 rl gene, encoding for Neural retina-specific leucine zipper protein, a rod fate determinant during ph

291 The basic leucine zipper transcription factor nuclear factor (eryt

292 abidopsis (Arabidopsis thaliana) homeodomain-leucine zipper transcription factor that participates in

293 This correlated inversely BATF (basic leucine zipper transcription factor, ATF-like) and IRF4

294 erized in depth the NLSs of a P. sojae basic leucine zipper transcription factor, PsbZIP1.

295 Leucine zipper transcription factor-like 1 (LZTFL1) was

296 M1-linked) di-ubiquitin to its coiled-coil 2-leucine zipper ubiquitin binding domain.

297 GILZ (glucocorticoid-induced leucine zipper) is inducible by glucocorticoids and play

298 de sequence attached to N-terminal of bZIP53 leucine zipper.

299 poE binding to ApoE receptors activates dual leucine-zipper kinase (DLK), a MAP-kinase kinase kinase

300 tial and sequence-specific approach by basic leucine-zipper transcriptional factors.