ライフサイエンスコーパス: leucine-rich

1 d rate of enamel regeneration and the use of leucine-rich amelogenin peptide (LRAP), a nonphosphoryla

2 our observation that in mice overexpressing leucine-rich amelogenin peptide (TgLRAP), in which amelo

3 The innate immune cell sensor leucine-rich-containing family, pyrin domain containing

4 the activation of nucleotide binding domain, leucine-rich-containing family, pyrin domain containing

5 sors, such as the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-

6 Recently, the nucleotide-binding domain, leucine-rich family (NLR), pyrin-containing 3 (NLRP3) in

7 ibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP).

8 The leucine-rich G protein-coupled receptor-5 (LGR5) is expr

9 (VGKC)-complex and the associated proteins, leucine-rich glioma inactivated 1 (LGI1) and contactin-a

10 Leucine-rich glioma inactivated 1 (LGI1) is a component

11 Leucine-rich glioma inactivated 1 (LGI1) is a secreted p

12 sitive cells through the production of LGI4 (Leucine-rich Glioma Inactivated 4) and nitric oxide (NO)

13 gamma-aminobutyric acid-B receptor (GABABR), leucine-rich glioma inactivated protein 1 (LGI1), contac

14 d potassium channel (VGKC) complex proteins, leucine-rich glioma-inactivated 1 (LGI1) and contactin-a

15 s, which target the extracellular domains of leucine-rich glioma-inactivated 1 (LGI1) and contactin-a

16 auditory features results from mutations in leucine-rich glioma-inactivated 1 (LGI1), a soluble glyc

17 potassium channel-complex related proteins (leucine-rich glioma-inactivated 1 and contactin-associat

18 iallelic loss-of-function mutations in LGI4 (leucine-rich glioma-inactivated 4).

19 0.7%) had VGKCc (4 of whom were positive for leucine-rich glioma-inactivated protein 1 [LGI1] Ab), an

20 Leucine-rich glioma-inactivated1 (LGI1) encephalitis is

21 Limbic encephalitis with leucine-rich, glioma-inactivated 1 (LGI1) antibodies is

22 ed with the potassium channel, in particular leucine-rich, glioma-inactivated protein 1 (LGI1) and co

23 In this study, we demonstrate that the leucine-rich hydrophobic sequence stretches (with the ce

24 o acids of the TEL [TPP1's glutamate (E) and leucine-rich (L)] patch, the surface of TPP1 that binds

25 paxillin signaling activity is regulated via leucine-rich LD motifs (LD1-LD5) located at the N-termin

26 In this study, we identify a leucine-rich motif at residues 717-724 that bears strong

27 cts with several short motifs, named helical leucine-rich motifs (HLMs), spread in the long C-termina

28 In K17, we defined and validated a leucine-rich NES that mediated CRM1 binding for export.

29 reas release into the cytoplasm requires two leucine-rich nuclear export sequences at the C-terminus.

30 y through the activity of Rev's prototypical leucine-rich nuclear export signal (NES).

31 ates the export of diverse cargos containing leucine-rich nuclear export signals (NESs) through compl

32 Prp40 possesses two leucine-rich nuclear export signals, but little is known

33 This encodes the leucine-rich pentatricopeptide repeat domain protein (LR

34 Here, we found that Drosophila leucine-rich pentatricopeptide repeat domain-containing

35 n as candidate substrates of mOGT, including leucine-rich PPR-containing protein and mitochondrial ac

36 PELP1 (proline, glutamic acid and leucine rich protein 1) is a nuclear receptor coregulato

37 smic localization of proline, glutamic acid, leucine-rich protein 1 (PELP1) is observed in approximat

38 t of ER, PR and the proline-, glutamate- and leucine-rich protein 1 (PELP1) to an estrogen response e

39 ere, we identify proline, glutamic acid, and leucine-rich protein 1 (PELP1), a chromatin-associated f

40 ollagen-associated proteins, including small leucine-rich proteins (SLRPs), but the regulatory mechan

41 ted by a family of collagen-associated small leucine-rich proteins (SLRPs).

42 Lumican, a small leucine rich proteoglycan (SLRP), is a component of extr

43 Decorin (DCN) is a small-leucine rich proteoglycan that mediates collagen fibrill

44 d, at least in part, by members of the small leucine-rich proteoglycan (SLRP) family.

45 We found that the gene encoding the small leucine-rich proteoglycan decorin (DCN) is repressed by

46 ent for glycoproteins, peptides of the small leucine-rich proteoglycan decorin were identified consis

47 -/-) mice shows reduced binding to the small leucine-rich proteoglycan decorin, a known regulator of

48 umor necrosis factor-alpha secrete the small leucine-rich proteoglycan lumican, and that lumican, but

49 Osteoglycin is a small leucine-rich proteoglycan previously described as a mark

50 Decorin, an archetypical small leucine-rich proteoglycan, initiates a protracted autoph

51 Small leucine-rich proteoglycans (SLRPs) are extracellular mat

52 Small leucine-rich proteoglycans interact with other extracell

53 We also found that mutation in the leucine-rich receptor kinase ERECTA and its putative pep

54 On examples of proteins with Leucine Rich Repeat (LRR) domains and other solenoids li

55 The cytosolic nucleotide binding site-leucine rich repeat (NBS-LRR) resistance proteins of pla

56 s nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 (NLRP1

57 a dependent on nucleotide-binding domain and leucine rich repeat containing family, pyrin domain cont

58 The Leucine rich repeat kinase 2 (LRRK2) gene is genetically

59 Leucine rich repeat kinase 2 (LRRK2) has been geneticall

60 Leucine rich repeat kinase 2 is a complex enzyme with bo

61 Pleckstrin homology domain and leucine rich repeat protein phosphatase 1 (PHLPP1) is a

62 resistance genes encoding nucleotide binding-leucine rich repeat proteins and genes encoding pentatri

63 a, encoding a coiled-coil nucleotide-binding leucine-rich repeat (CC-NB-LRR) protein.

64 most N-terminal domain of Reck binds to the leucine-rich repeat (LRR) and immunoglobulin (Ig) domain

65 is repressed by a flanking substrate-binding leucine-rich repeat (LRR) domain when substrate is absen

66 CCR4s contain N-terminal leucine-rich repeat (LRR) motifs that interact with CAF1

67 port isolation and identification of a novel Leucine-Rich Repeat (LRR) protein that directly interact

68 mutants encodes a receptor lacking a single leucine-rich repeat (LRR) within its N-terminus.

69 a ubiquitously expressed gene that encodes a leucine-rich repeat (LRR)-containing protein detected at

70 his study, we identified LRRC25, a member of leucine-rich repeat (LRR)-containing protein family, as

71 After ligand perception, many leucine-rich repeat (LRR)-containing PRRs interact with

72 eotide-binding (NB) domain, and a C-terminal leucine-rich repeat (LRR).

73 ition, plants use the nucleotide-binding and leucine-rich repeat (NB-LRR) domain-containing resistanc

74 Several plant nucleotide-binding, leucine-rich repeat (NB-LRR) immune receptors carry fusi

75 Nucleotide-binding leucine-rich repeat (NB-LRR, or NLR) receptors mediate p

76 ition of XopQ 1 (Roq1), a nucleotide-binding leucine-rich repeat (NLR) protein with a Toll-like inter

77 ical to VICTR, encoding a nucleotide-binding leucine-rich repeat (NLR) protein(3).

78 med RPS5, which encodes a nucleotide-binding leucine-rich repeat (NLR) protein.

79 Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are a diverse family

80 Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for th

81 Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable cells to respo

82 Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable plants to reco

83 Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable the immune sys

84 Nucleotide-binding domain leucine-rich repeat (NLR) proteins function as cytosolic

85 stance genes encoding for nucleotide-binding leucine-rich repeat (NLR) proteins hampers their predict

86 Nucleotide-binding leucine-rich repeat (NLR) proteins serve as immune recep

87 ted by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins.

88 Intracellular nucleotide-binding leucine-rich repeat (NLR) receptors play central roles i

89 r proteins of the nucleotide-binding domain, leucine-rich repeat (NLR) superfamily to detect many typ

90 OUS MIX2 (DM2) nucleotide-binding domain and leucine-rich repeat (NLR)-encoding locus in A. thaliana.

91 NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]-containing proteins) exhibit d

92 me of Ewing and showed unexpectedly that the leucine-rich repeat and Ig domain protein 1 (LINGO1) is

93 Leucine-rich repeat and Ig-like domain-containing Nogo r

94 We previously demonstrated that leucine-rich repeat and Ig-like domain-containing Nogo r

95 LRIG1 (leucine-rich repeat and immunoglobulin-like domain conta

96 d nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NRLP3

97 ng and oligomerization domain-like receptor, leucine-rich repeat and pyrin domain-containing 3 (NLRP3

98 nase kinases (MKKs) and rodent NLRP1B (NACHT leucine-rich repeat and pyrin domain-containing protein

99 the emerging concept that nucleotide-binding leucine-rich repeat and pyrin domain-containing receptor

100 evious predictions of a chitinase domain and leucine-rich repeat but also revealed a putative carbohy

101 Both nucleotide-binding domain and leucine-rich repeat caspase recruitment domain 4 and nuc

102 long to the coiled-coil, nucleotide-binding, leucine-rich repeat class of intracellular immune recept

103 Recently, several leucine-rich repeat containing (LRRC) proteins have been

104 mation through nucleotide-binding domain and leucine-rich repeat containing (NLRP3) inflammasome, whi

105 nical events except stroke, the LRRC3B gene (leucine-rich repeat containing 3B) with myocardial infar

106 Leucine-rich repeat containing 8A (LRRC8A) is an ubiquit

107 showing that multimers derived from LRRC8A (leucine-rich repeat containing 8A) gene are structural c

108 iversal beta-catenin target gene expression, leucine-rich repeat containing G protein-coupled recepto

109 Leucine-rich repeat containing G-protein-coupled recepto

110 tly characterized nucleotide-binding domain, leucine-rich repeat containing protein (NLR) that negati

111 Here, we report that leucine-rich repeat containing protein 25 (LRRC25) is a

112 he expression and physiological functions of leucine-rich repeat containing protein 26 (LRRC26) in ar

113 re the role of the nucleotide-binding domain leucine-rich repeat containing receptor family member Nl

114 he role of the nucleotide-binding domain and leucine-rich repeat containing receptor NLRP10 in diseas

115 1 component (S519C16) of S519 with the first leucine-rich repeat domain (L1) of the insulin receptor.

116 alpha dissociation and unfolds the GPIbalpha leucine-rich repeat domain (LRRD) and juxtamembrane mech

117 Scribble consists of a leucine-rich repeat domain and four PDZ domains, with th

118 through two identified binding sites in its leucine-rich repeat domain and regulating collagen fibri

119 The tyrosine-sulfated domain and the leucine-rich repeat domain both bound to three specific

120 The isolated leucine-rich repeat domain inhibited the fibril formatio

121 flammasome required NEK7, which bound to the leucine-rich repeat domain of NLRP3 in a kinase-independ

122 otide binding oligomerization domain and the leucine-rich repeat domain of NLRP3 were the intracellul

123 ocytes, GPSM3 associates with the C-terminal leucine-rich repeat domain of NLRP3.

124 The leucine-rich repeat domain of PP32 is composed of five b

125 They are composed of an extracellular leucine-rich repeat domain responsible for detecting pat

126 domain gene product containing an N-terminal leucine-rich repeat domain, followed by a likely posttra

127 e plant can evolve nucleotide-binding domain-leucine-rich repeat domain-containing proteins to recogn

128 Proteins with nucleotide binding and leucine-rich repeat domains (NLRs) serve as immune recep

129 transmembrane proteins characterized by six leucine-rich repeat domains and one immunoglobulin-like

130 g because the N-terminal Pyrin or C-terminal leucine-rich repeat domains were dispensable.

131 Moreover, the leucine-rich repeat domains, and specifically four amino

132 We show that Drosophila leucine-rich repeat G protein-coupled receptor 3 (Lgr3)

133 Here, we show that Leucine-rich repeat kinase (Lrrk), the Drosophila melano

134 The leucine-rich repeat kinase (LRRK)-2 protein contains non

135 Our studies identify leucine-rich repeat kinase 1 (LRRK1), a key regulator of

136 Mutations in leucine-rich repeat kinase 2 (LRRK2) and alpha-synuclein

137 Mutations in leucine-rich repeat kinase 2 (LRRK2) are a common cause

138 Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are a common geneti

139 Mutations in leucine-rich repeat kinase 2 (LRRK2) are associated with

140 Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common

141 Mutations in leucine-rich repeat kinase 2 (Lrrk2) are the most common

142 Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common

143 Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) can cause Parkinson

144 Mutations in leucine-rich repeat kinase 2 (LRRK2) cause autosomal-dom

145 Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Par

146 Mutations in leucine-rich repeat kinase 2 (LRRK2) cause late-onset, a

147 Mutations in leucine-rich repeat kinase 2 (LRRK2) contribute to devel

148 Mutations in the kinase domain of leucine-rich repeat kinase 2 (LRRK2) follow Parkinson's

149 Although the Leucine-rich repeat kinase 2 (LRRK2) G2019S missense mut

150 Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most c

151 Missense mutations in the leucine-rich repeat kinase 2 (LRRK2) gene can cause late

152 Genetic variation in the leucine-rich repeat kinase 2 (LRRK2) gene is associated

153 Leucine-rich repeat kinase 2 (LRRK2) has been associated

154 Parkinson's disease gene leucine-rich repeat kinase 2 (LRRK2) has been implicated

155 Leucine-rich repeat kinase 2 (LRRK2) has been linked to

156 Multiple missense mutations in Leucine-rich repeat kinase 2 (LRRK2) have been linked to

157 emical studies implicate alpha-synuclein and leucine-rich repeat kinase 2 (LRRK2) in late-onset PD.

158 Leucine-rich repeat kinase 2 (LRRK2) is a large, multido

159 Leucine-rich repeat kinase 2 (LRRK2) is a large, multido

160 Leucine-rich repeat kinase 2 (LRRK2) is a multi-domain e

161 Leucine-rich repeat kinase 2 (LRRK2) is a multidomain pr

162 Leucine-rich repeat kinase 2 (LRRK2) is the single most

163 Mutations in leucine-rich repeat kinase 2 (LRRK2) lead to late-onset,

164 Leucine-rich repeat kinase 2 (LRRK2) mutation 6055G-->A

165 Leucine-rich repeat kinase 2 (LRRK2) mutations are the m

166 The leucine-rich repeat kinase 2 (LRRK2) protein has been ge

167 tions in Park8, encoding for the multidomain Leucine-rich repeat kinase 2 (LRRK2) protein, comprise t

168 issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of

169 LRRK2, encoding the multifunctional protein leucine-rich repeat kinase 2 (LRRK2), are a common cause

170 nes linked to genetic forms of PD, including leucine-rich repeat kinase 2 (LRRK2), functionally conve

171 unknown, but several genetic loci, including leucine-rich repeat kinase 2 (LRRK2), have been identifi

172 ociated gene for leucine-rich repeat kinase, leucine-rich repeat kinase 2 (LRRK2), is highly expresse

173 Mutations in leucine-rich repeat kinase 2 (LRRK2), such as G2019S, ar

174 encoding a-synuclein (SNCA), tau (MAPT), and leucine-rich repeat kinase 2 (LRRK2).

175 se of Parkinson's disease (PD), mutations in leucine-rich repeat kinase 2 (LRRK2).

176 al effects of a common PD-linked mutation of leucine-rich repeat kinase 2 in the mouse hippocampus, a

177 LRRK2 (leucine-rich repeat kinase) mutations constitute the mos

178 The common PD-associated gene for leucine-rich repeat kinase, leucine-rich repeat kinase 2

179 Mutations in the leucine-rich repeat kinase-2 (LRRK2) gene cause autosoma

180 Alpha-synuclein (SNCA) and Leucine-rich repeat kinase2 (LRRK2) have been implicated

181 idues on the concave surfaces of neighboring leucine-rich repeat modules assists in stabilizing the o

182 hibit caspase-1 activation by the NLR family leucine-rich repeat protein (NLRP)1 and NLRP3 inflammaso

183 r matrix component proline/arginine-rich end leucine-rich repeat protein (PRELP) is a novel antibacte

184 he EMT inducer Twist1 by enhancing F-box and leucine-rich repeat protein 14 (FBXL14)-mediated polyubi

185 Here, we show that Fbxl17 (F-box and leucine-rich repeat protein 17) targets Sufu for proteol

186 is capable of triggering NLRP3 (NLR-family, leucine-rich repeat protein 3) inflammasome activation a

187 usly unrecognized role for the transmembrane leucine-rich repeat protein Lapsyn in regulating mng dev

188 We show that the phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP) downstre

189 we show that the pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP) suppress

190 n this study, we demonstrated that PH domain leucine-rich repeat protein phosphatase (PHLPP), a novel

191 we identified pleckstrin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) as a

192 co-localization of Akt and PHLPP1 (PH domain leucine-rich repeat protein phosphatase isoform 1), a Se

193 tion of the translation of the PH domain and leucine-rich repeat protein phosphatases 1 (PHLPP1), a p

194 1.2 encodes a coiled-coil nucleotide-binding leucine-rich repeat protein that in addition to potato a

195 rice gene Xa1, encoding a nucleotide-binding leucine-rich repeat protein, confers resistance against

196 Surprisingly, a single transmembrane leucine-rich repeat protein, DMA-1, plays a major role i

197 c map of the entire folding landscape of the leucine-rich repeat protein, pp32 (Anp32), obtained by c

198 Nucleotide binding domain and leucine-rich repeat proteins (NLRs) are important recept

199 Nucleotide-binding leucine-rich repeat proteins (NLRs) serve as intracellul

200 enes encoding coiled-coil nucleotide-binding leucine-rich repeat proteins designated CNL3 and CNL13.

201 Small leucine-rich repeat proteoglycan (SLRP) family proteins

202 t domain 4 and nucleotide-binding domain and leucine-rich repeat pyrin domain 3 are simultaneously pr

203 ulators of the nucleotide-binding domain and leucine-rich repeat pyrin domain containing 3 inflammaso

204 and activate the nucleotide-binding domain, leucine-rich repeat pyrin domain-containing 3 (NLRP3) in

205 ovo assembly of complete nucleotide-binding, leucine-rich repeat receptor (NLR) genes, their regulato

206 patterns by a nucleotide-binding domain and leucine-rich repeat receptor (NLR) or absent in melanoma

207 Floral abscission is controlled by the leucine-rich repeat receptor kinase (LRR-RK) HAESA and t

208 Phytosulfokine (PSK) is perceived by the leucine-rich repeat receptor kinase PSKR1 and promotes g

209 by direct binding to the membrane-localized leucine-rich repeat receptor kinases, PEP RECEPTOR1 (PEP

210 termined that BAM1, which is a member of the leucine-rich repeat receptor-like kinase (LRR-RLK) famil

211 that the constitutive activation of NIK1, a leucine-rich repeat receptor-like kinase (LRR-RLK) ident

212 d resistance to GPA that is dependent on the leucine-rich repeat receptor-like kinase BRASSINOSTEROID

213 roid insensitive 1 (BRI1) is a member of the leucine-rich repeat receptor-like kinase family.

214 n of the plasma membrane-localized, atypical leucine-rich repeat receptor-like kinase POLLEN-SPECIFIC

215 d to a shoot receptor complex containing the leucine-rich repeat receptor-like kinase SUNN, triggerin

216 liana plant architecture, ERECTA, encoding a leucine-rich repeat receptor-like kinase.

217 Leucine-rich repeat receptor-like kinases (LRR RLKs) for

218 st to G protein activation in animals, plant leucine-rich repeat receptor-like kinases (LRR RLKs), no

219 nases expanded massively in land plants, and leucine-rich repeat receptor-like kinases (LRR-RLK) cons

220 Cell signaling pathways mediated by leucine-rich repeat receptor-like kinases (LRR-RLKs) are

221 the CLE family interacting with CLAVATA1 and leucine-rich repeat receptor-like kinases (LRR-RLKs).

222 hamiana, which also involves the Arabidopsis leucine-rich repeat receptor-like protein SOBIR1 (for SU

223 BPG1), an Arabidopsis (Arabidopsis thaliana) leucine-rich repeat receptor-like protein, AtRLP42, that

224 i, including proteins putatively involved in leucine-rich repeat recognition activity, second messeng

225 Nucleotide-binding site leucine-rich repeat resistance genes (NLRs) allow plants

226 Shoc2 is a leucine-rich repeat scaffold protein that acts as a posi

227 ike mechanism that employs flanking variable leucine-rich repeat sequences as templates in associatio

228 PR library targeting the immunity-associated leucine-rich repeat subfamily XII genes, heritable mutat

229 rs designated "nucleotide-binding domain and leucine-rich repeat" (NLR) proteins that translate patho

230 1 does so via the nucleotide-binding domain, leucine-rich repeat, pyrin domain containing protein 3 (

231 NLR, nucleotide binding and oligomerization, leucine-rich repeat, pyrin domain-containing 3 (NLRP3),

232 LAT); B-cell CLL/lymphoma 11B (BCL11B); RGD, leucine-rich repeat, tropomodulin domain, and proline-ri

233 The nucleotide binding domain and leucine-rich repeat-containing (NLR) family of proteins

234 Leucine-rich repeat-containing 8 (LRRC8) proteins have b

235 In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, apoptosis inhibit

236 IPs) activate the nucleotide-binding domain, leucine-rich repeat-containing family, CARD domain-conta

237 We show here that the orphan receptor leucine-rich repeat-containing G protein-coupled recepto

238 Here, we report on Lgr5 and Lgr6 (leucine-rich repeat-containing G protein-coupled recepto

239 eins and their cognate receptors, members of leucine-rich repeat-containing G protein-coupled recepto

240 s receptor, DLGR2, the ortholog of mammalian leucine-rich repeat-containing G protein-coupled recepto

241 Leucine-rich repeat-containing G protein-coupled recepto

242 , we report a pivotal role for the R-spondin/leucine-rich repeat-containing G protein-coupled recepto

243 rkers, epithelial cell adhesion molecule and leucine-rich repeat-containing G protein-coupled recepto

244 ified Wnt environment leads to activation of leucine-rich repeat-containing G-protein coupled recepto

245 Leucine-rich repeat-containing G-protein coupled recepto

246 rapidly growing adenomas containing LGR5(+) (leucine-rich repeat-containing G-protein coupled recepto

247 g lineage tracing to mark cells derived from leucine-rich repeat-containing G-protein coupled recepto

248 Herein we report that leucine-rich repeat-containing G-protein-coupled recepto

249 re we report that the abundant expression of leucine-rich repeat-containing G-protein-coupled recepto

250 duced inhibition of Wnt signaling depends on leucine-rich repeat-containing G-protein-coupled recepto

251 Leucine-rich repeat-containing G-protein-coupled recepto

252 Here we show that the leucine-rich repeat-containing G-protein-coupled recepto

253 The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, freque

254 o the B-family (or secretin-like), and 2 are leucine-rich repeat-containing GPCRs.

255 Nucleotide-binding domain, leucine-rich repeat-containing protein (NLR)P3 inflammas

256 cing mRNA expression of the BK gamma subunit leucine-rich repeat-containing protein 26 (LRRC26) and i

257 nted by a trait-associated SNP and encodes a leucine-rich repeat-containing protein.

258 are sensed by nucleotide binding domain and leucine-rich repeat-containing proteins (NLRs), which tr

259 a member of the LRIG family of transmembrane leucine-rich repeat-containing proteins, is a negative r

260 KINASE3, which is a key regulator of several leucine-rich repeat-containing PRRs.

261 eotide-binding oligomerization domain (Nod), leucine-rich repeat-containing receptors (NLRs), and pyr

262 creased glomerular nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyr

263 eceded presence of nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyr

264 es with pyrin and nucleotide-binding domain, leucine-rich repeat/pyrin domain-containing 3.

265 ique among the nucleotide-binding-domain and leucine-rich-repeat (NLR) proteins in its mitochondrial

266 tf13, defining it as an F-box protein of the leucine-rich-repeat family, and demonstrates how a novel

267 Mutation in leucine-rich-repeat kinase 2 (LRRK2) is a common cause o

268 s in the expansion of nucleotide-binding and leucine-rich-repeat proteins (NLRs), the major disease-r

269 Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell

270 ules neurexin-1beta, neuroligin-1 (Nlg1) and leucine-rich-repeat transmembrane protein 2 (LRRTM2) in

271 tor (TLR) and nucleotide-binding domain- and leucine-rich-repeat-containing receptor (NLR) pathway ge

272 activation of the nucleotide-binding domain, leucine-rich-repeat-containing receptor (NLR), pyrin-dom

273 st these factors using mutant LRRK2(R1441G) (leucine-rich-repeat-kinase-2) knockin mice.

274 , Epithelial cell adhesion molecule (EpCAM), Leucine-rich repeated-containing G-protein coupled recep

275 scaffold protein composed almost entirely by leucine-rich repeats (LRRs) and having an N-terminal reg

276 d cytoplasmic protein that contains multiple leucine-rich repeats (LRRs) and interacts with integrin-

277 c screen for genes encoding proteins bearing leucine-rich repeats (LRRs) and nucleotide-binding domai

278 usly expressed transmembrane protein with 17 leucine-rich repeats (LRRs) at its C-terminal end and is

279 TLR4 interactor with leucine-rich repeats (TRIL) is a brain-enriched accessor

280 ng a high affinity interaction involving the leucine-rich repeats and a predicted lower affinity inte

281 large extracellular domain consisting of 10 leucine-rich repeats and an N-terminal low density lipop

282 ses an additional 33 amino acids between the leucine-rich repeats and carboxy-terminal low-complexity

283 Leucine-rich repeats and immunoglobulin-like domains 1 (

284 Here, we found that leucine-rich repeats and immunoglobulin-like domains 1 (

285 Leucine-rich repeats and immunoglobulin-like domains pro

286 es contained heparanase 1, heparanase 2, and leucine-rich repeats and immunoglobulin-like domains-2 (

287 (CITA), NLRC5 [nucleotide-binding domain and leucine-rich repeats containing (NLR) family, caspase ac

288 n VRACs was obtained by the discovery of the leucine-rich repeats containing 8A (LRRC8A) gene.

289 Finally, we find that the Prf leucine-rich repeats domain also binds the N-terminal re

290 complex, composed of the nucleotide-binding leucine-rich repeats protein Prf and the protein kinase

291 NLRs (nucleotide-binding domain and leucine-rich repeats) belong to a large family of cytopl

292 a central nucleotide binding and C-terminal leucine-rich repeats).

293 domain of the NAIPs, rather than within the leucine-rich repeats, as was anticipated.

294 e substrate-binding domain of Dia2 comprises leucine-rich repeats, but Dia2 also has a TPR domain at

295 hocyte receptors (VLRs) composed of variable leucine-rich repeats, which are differentially expressed

296 ng on the NLRX1 (nucleotide-binding, lots of leucine-rich repeats-containing protein member X1)-TUFM

297 ibited by intramolecular binding to the Vms1 leucine-rich sequence (LRS).

298 also found that Lys-714 was located within a leucine-rich stretch, which resembles a nuclear export s

299 Here, we determined that fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsiv

300 eurons in Caenorhabditis elegans through the leucine-rich transmembrane receptor DMA-1/LRR-TM express