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1 a central nucleotide binding and C-terminal leucine-rich repeats).
2 461, which are located on the convex face of leucine-rich repeats 16 and 17 of the mTLR4 ectodomain,
3 s nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 (NLRP1
4 me of Ewing and showed unexpectedly that the leucine-rich repeat and Ig domain protein 1 (LINGO1) is
8 d nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NRLP3
9 ng and oligomerization domain-like receptor, leucine-rich repeat and pyrin domain-containing 3 (NLRP3
10 nase kinases (MKKs) and rodent NLRP1B (NACHT leucine-rich repeat and pyrin domain-containing protein
11 the emerging concept that nucleotide-binding leucine-rich repeat and pyrin domain-containing receptor
12 lies are determined for the F-box-containing leucine-rich repeat and WD40 repeat families, but not fo
13 ng a high affinity interaction involving the leucine-rich repeats and a predicted lower affinity inte
14 large extracellular domain consisting of 10 leucine-rich repeats and an N-terminal low density lipop
15 ses an additional 33 amino acids between the leucine-rich repeats and carboxy-terminal low-complexity
19 es contained heparanase 1, heparanase 2, and leucine-rich repeats and immunoglobulin-like domains-2 (
22 evious predictions of a chitinase domain and leucine-rich repeat but also revealed a putative carbohy
23 e substrate-binding domain of Dia2 comprises leucine-rich repeats, but Dia2 also has a TPR domain at
24 with the unstructured amino-terminal and the leucine-rich repeat carboxy-terminal domains of Tmod.
27 long to the coiled-coil, nucleotide-binding, leucine-rich repeat class of intracellular immune recept
28 a dependent on nucleotide-binding domain and leucine rich repeat containing family, pyrin domain cont
29 e identify the nucleotide-binding domain and leucine rich repeat containing family, pyrin domain cont
31 mation through nucleotide-binding domain and leucine-rich repeat containing (NLRP3) inflammasome, whi
32 nical events except stroke, the LRRC3B gene (leucine-rich repeat containing 3B) with myocardial infar
34 showing that multimers derived from LRRC8A (leucine-rich repeat containing 8A) gene are structural c
36 iversal beta-catenin target gene expression, leucine-rich repeat containing G protein-coupled recepto
38 tly characterized nucleotide-binding domain, leucine-rich repeat containing protein (NLR) that negati
40 he expression and physiological functions of leucine-rich repeat containing protein 26 (LRRC26) in ar
42 re the role of the nucleotide-binding domain leucine-rich repeat containing receptor family member Nl
43 he role of the nucleotide-binding domain and leucine-rich repeat containing receptor NLRP10 in diseas
45 subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) pr
46 (CITA), NLRC5 [nucleotide-binding domain and leucine-rich repeats containing (NLR) family, caspase ac
50 In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, apoptosis inhibit
51 es include the nucleotide-binding domain and leucine-rich repeat-containing family, calcium channel s
52 IPs) activate the nucleotide-binding domain, leucine-rich repeat-containing family, CARD domain-conta
53 ndependent of the nucleotide-binding domain, leucine-rich repeat-containing family, pyrin domain-cont
56 eins and their cognate receptors, members of leucine-rich repeat-containing G protein-coupled recepto
57 s receptor, DLGR2, the ortholog of mammalian leucine-rich repeat-containing G protein-coupled recepto
59 , we report a pivotal role for the R-spondin/leucine-rich repeat-containing G protein-coupled recepto
60 rkers, epithelial cell adhesion molecule and leucine-rich repeat-containing G protein-coupled recepto
61 rapidly growing adenomas containing LGR5(+) (leucine-rich repeat-containing G-protein coupled recepto
62 g lineage tracing to mark cells derived from leucine-rich repeat-containing G-protein coupled recepto
64 ified Wnt environment leads to activation of leucine-rich repeat-containing G-protein coupled recepto
66 re we report that the abundant expression of leucine-rich repeat-containing G-protein-coupled recepto
67 duced inhibition of Wnt signaling depends on leucine-rich repeat-containing G-protein-coupled recepto
69 ate that TLR4 induces ER stress within Lgr5 (leucine-rich repeat-containing G-protein-coupled recepto
73 ) and conditional (Vil-CreER;Adam10(f/f) and Leucine-rich repeat-containing GPCR5 [Lgr5]-CreER;Adam10
76 cing mRNA expression of the BK gamma subunit leucine-rich repeat-containing protein 26 (LRRC26) and i
78 are sensed by nucleotide binding domain and leucine-rich repeat-containing proteins (NLRs), which tr
79 a member of the LRIG family of transmembrane leucine-rich repeat-containing proteins, is a negative r
82 eotide-binding oligomerization domain (Nod), leucine-rich repeat-containing receptors (NLRs), and pyr
83 otein of the NLR (nucleotide-binding domain, leucine-rich repeat-containing) superfamily or the PYHIN
84 creased glomerular nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyr
85 eceded presence of nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyr
86 , Epithelial cell adhesion molecule (EpCAM), Leucine-rich repeated-containing G-protein coupled recep
87 ng on the NLRX1 (nucleotide-binding, lots of leucine-rich repeats-containing protein member X1)-TUFM
88 Here we found that the nucleotide-binding, leucine-rich-repeat-containing protein, NLRC3, reduced S
89 tor (TLR) and nucleotide-binding domain- and leucine-rich-repeat-containing receptor (NLR) pathway ge
90 activation of the nucleotide-binding domain, leucine-rich-repeat-containing receptor (NLR), pyrin-dom
91 1 component (S519C16) of S519 with the first leucine-rich repeat domain (L1) of the insulin receptor.
92 alpha dissociation and unfolds the GPIbalpha leucine-rich repeat domain (LRRD) and juxtamembrane mech
94 through two identified binding sites in its leucine-rich repeat domain and regulating collagen fibri
97 flammasome required NEK7, which bound to the leucine-rich repeat domain of NLRP3 in a kinase-independ
98 otide binding oligomerization domain and the leucine-rich repeat domain of NLRP3 were the intracellul
101 This work demonstrates that changes in the leucine-rich repeat domain of the TIR1 auxin coreceptor
103 domain gene product containing an N-terminal leucine-rich repeat domain, followed by a likely posttra
104 e plant can evolve nucleotide-binding domain-leucine-rich repeat domain-containing proteins to recogn
107 transmembrane proteins characterized by six leucine-rich repeat domains and one immunoglobulin-like
111 tf13, defining it as an F-box protein of the leucine-rich-repeat family, and demonstrates how a novel
114 coccum is a coiled-coil, nucleotide-binding, leucine-rich repeat gene that confers near immunity to U
115 RenSeq is a NB-LRR (nucleotide binding-site leucine-rich repeat) gene-targeted, Resistance gene enri
116 inct protein domains, including glycosidase, leucine-rich repeat, hybrid Ig, carbohydrate binding mod
149 emical studies implicate alpha-synuclein and leucine-rich repeat kinase 2 (LRRK2) in late-onset PD.
161 tions in Park8, encoding for the multidomain Leucine-rich repeat kinase 2 (LRRK2) protein, comprise t
162 issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of
163 LRRK2, encoding the multifunctional protein leucine-rich repeat kinase 2 (LRRK2), are a common cause
164 nes linked to genetic forms of PD, including leucine-rich repeat kinase 2 (LRRK2), functionally conve
165 unknown, but several genetic loci, including leucine-rich repeat kinase 2 (LRRK2), have been identifi
166 ociated gene for leucine-rich repeat kinase, leucine-rich repeat kinase 2 (LRRK2), is highly expresse
170 al effects of a common PD-linked mutation of leucine-rich repeat kinase 2 in the mouse hippocampus, a
179 most N-terminal domain of Reck binds to the leucine-rich repeat (LRR) and immunoglobulin (Ig) domain
181 is repressed by a flanking substrate-binding leucine-rich repeat (LRR) domain when substrate is absen
183 ly (IgSF), fibronectin type III (FnIII), and leucine-rich repeat (LRR) families, which are known to b
185 port isolation and identification of a novel Leucine-Rich Repeat (LRR) protein that directly interact
188 3 (CLV3), and its perception by cell surface leucine-rich repeat (LRR) receptors, including the CLV1
190 a ubiquitously expressed gene that encodes a leucine-rich repeat (LRR)-containing protein detected at
191 his study, we identified LRRC25, a member of leucine-rich repeat (LRR)-containing protein family, as
192 r that developing and mature HCs express the leucine-rich repeat (LRR)-containing protein netrin-G li
196 NLR (nucleotide-binding domain [NBD]- and leucine-rich repeat [LRR]-containing) proteins mediate i
197 scaffold protein composed almost entirely by leucine-rich repeats (LRRs) and having an N-terminal reg
198 d cytoplasmic protein that contains multiple leucine-rich repeats (LRRs) and interacts with integrin-
199 c screen for genes encoding proteins bearing leucine-rich repeats (LRRs) and nucleotide-binding domai
200 usly expressed transmembrane protein with 17 leucine-rich repeats (LRRs) at its C-terminal end and is
201 vo design of capping structures, we designed leucine-rich repeats (LRRs) from the ribonuclease inhibi
202 ained interaction between A1 and the central leucine-rich repeats (LRRs) of GPIbalpha, previously sho
203 idues on the concave surfaces of neighboring leucine-rich repeat modules assists in stabilizing the o
204 ition, plants use the nucleotide-binding and leucine-rich repeat (NB-LRR) domain-containing resistanc
209 by members of the nucleotide binding domain leucine-rich repeat (NLR) protein family that respond to
210 ition of XopQ 1 (Roq1), a nucleotide-binding leucine-rich repeat (NLR) protein with a Toll-like inter
219 stance genes encoding for nucleotide-binding leucine-rich repeat (NLR) proteins hampers their predict
223 r proteins of the nucleotide-binding domain, leucine-rich repeat (NLR) superfamily to detect many typ
224 OUS MIX2 (DM2) nucleotide-binding domain and leucine-rich repeat (NLR)-encoding locus in A. thaliana.
225 ique among the nucleotide-binding-domain and leucine-rich-repeat (NLR) proteins in its mitochondrial
226 rs designated "nucleotide-binding domain and leucine-rich repeat" (NLR) proteins that translate patho
227 overexpression down-regulated PH domain and leucine-rich repeat phosphatase (PHLPP) and that PHLPP o
229 hibit caspase-1 activation by the NLR family leucine-rich repeat protein (NLRP)1 and NLRP3 inflammaso
230 r matrix component proline/arginine-rich end leucine-rich repeat protein (PRELP) is a novel antibacte
231 he EMT inducer Twist1 by enhancing F-box and leucine-rich repeat protein 14 (FBXL14)-mediated polyubi
233 ulators, casein kinase 1 (CKI) and F-box and leucine-rich repeat protein 3 (FBXL3), modulate the stab
234 is capable of triggering NLRP3 (NLR-family, leucine-rich repeat protein 3) inflammasome activation a
235 The hemerythrin-like domain of F-box and leucine-rich repeat protein 5 (FBXL5), an E3 ubiquitin l
236 te that reovirus binds Nogo receptor NgR1, a leucine-rich repeat protein expressed in the CNS, to inf
237 usly unrecognized role for the transmembrane leucine-rich repeat protein Lapsyn in regulating mng dev
239 we show that the pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP) suppress
240 n this study, we demonstrated that PH domain leucine-rich repeat protein phosphatase (PHLPP), a novel
241 we identified pleckstrin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) as a
242 tion of two splice variants of PH domain and Leucine-rich repeat Protein Phosphatase 1 (PHLPP1), PHLP
243 co-localization of Akt and PHLPP1 (PH domain leucine-rich repeat protein phosphatase isoform 1), a Se
245 tion of the translation of the PH domain and leucine-rich repeat protein phosphatases 1 (PHLPP1), a p
246 1.2 encodes a coiled-coil nucleotide-binding leucine-rich repeat protein that in addition to potato a
247 rice gene Xa1, encoding a nucleotide-binding leucine-rich repeat protein, confers resistance against
249 c map of the entire folding landscape of the leucine-rich repeat protein, pp32 (Anp32), obtained by c
250 complex, composed of the nucleotide-binding leucine-rich repeats protein Prf and the protein kinase
251 resistance genes encoding nucleotide binding-leucine rich repeat proteins and genes encoding pentatri
254 proteins interacted with nucleotide binding-leucine-rich repeat proteins and effector proteins, sugg
255 enes encoding coiled-coil nucleotide-binding leucine-rich repeat proteins designated CNL3 and CNL13.
256 Variable lymphocyte receptors (VLRs) are leucine-rich repeat proteins that mediate adaptive immun
257 s in the expansion of nucleotide-binding and leucine-rich-repeat proteins (NLRs), the major disease-r
259 The mouse nucleotide-binding domain and leucine rich repeat pyrin containing 1b (NLRP1b) inflamm
260 t domain 4 and nucleotide-binding domain and leucine-rich repeat pyrin domain 3 are simultaneously pr
261 ulators of the nucleotide-binding domain and leucine-rich repeat pyrin domain containing 3 inflammaso
262 and activate the nucleotide-binding domain, leucine-rich repeat pyrin domain-containing 3 (NLRP3) in
263 1 does so via the nucleotide-binding domain, leucine-rich repeat, pyrin domain containing protein 3 (
264 NLR, nucleotide binding and oligomerization, leucine-rich repeat, pyrin domain-containing 3 (NLRP3),
266 endocytosis of transferrin, FM-4-64, and the leucine rich repeat receptor like protein LeEix2, an eff
267 ovo assembly of complete nucleotide-binding, leucine-rich repeat receptor (NLR) genes, their regulato
268 patterns by a nucleotide-binding domain and leucine-rich repeat receptor (NLR) or absent in melanoma
270 Phytosulfokine (PSK) is perceived by the leucine-rich repeat receptor kinase PSKR1 and promotes g
271 by direct binding to the membrane-localized leucine-rich repeat receptor kinases, PEP RECEPTOR1 (PEP
272 termined that BAM1, which is a member of the leucine-rich repeat receptor-like kinase (LRR-RLK) famil
273 that the constitutive activation of NIK1, a leucine-rich repeat receptor-like kinase (LRR-RLK) ident
274 d resistance to GPA that is dependent on the leucine-rich repeat receptor-like kinase BRASSINOSTEROID
276 SR-related) peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase is expressed in
277 n of the plasma membrane-localized, atypical leucine-rich repeat receptor-like kinase POLLEN-SPECIFIC
278 d to a shoot receptor complex containing the leucine-rich repeat receptor-like kinase SUNN, triggerin
281 st to G protein activation in animals, plant leucine-rich repeat receptor-like kinases (LRR RLKs), no
282 nases expanded massively in land plants, and leucine-rich repeat receptor-like kinases (LRR-RLK) cons
283 , mitogen-activated protein kinases (MAPKs), leucine-rich repeat receptor-like kinases (LRR-RLKs) and
285 the CLE family interacting with CLAVATA1 and leucine-rich repeat receptor-like kinases (LRR-RLKs).
286 d BAK1(SERK3) in the natural habitat of both leucine-rich repeat receptor-like kinases using comparat
287 hamiana, which also involves the Arabidopsis leucine-rich repeat receptor-like protein SOBIR1 (for SU
288 BPG1), an Arabidopsis (Arabidopsis thaliana) leucine-rich repeat receptor-like protein, AtRLP42, that
290 Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell
291 i, including proteins putatively involved in leucine-rich repeat recognition activity, second messeng
294 ike mechanism that employs flanking variable leucine-rich repeat sequences as templates in associatio
295 PR library targeting the immunity-associated leucine-rich repeat subfamily XII genes, heritable mutat
296 e that cooperativity requires the N-terminal leucine-rich repeat-targeting domain and is transduced t
297 ules neurexin-1beta, neuroligin-1 (Nlg1) and leucine-rich-repeat transmembrane protein 2 (LRRTM2) in
299 LAT); B-cell CLL/lymphoma 11B (BCL11B); RGD, leucine-rich repeat, tropomodulin domain, and proline-ri
300 hocyte receptors (VLRs) composed of variable leucine-rich repeats, which are differentially expressed
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