ライフサイエンスコーパス: leucocyte

1 sequently confirmed by enzyme measurement on leucocytes.

2 s differ quite radically from those in other leucocytes.

3 heir ability to bind and recruit circulating leucocytes.

4 y to induce migration of specific subsets of leucocytes.

5 lysis of reverse transcribed mRNA from blood leucocytes.

6 ve better imaging results than radiolabelled leucocytes.

7 howed the same Y-chromosome deletion seen in leucocytes.

8 WGS was performed in tumour and leucocytes.

9 odern studies on eosinophils and other blood leucocytes.

10 us-induced ER stress and type I IFN in human leucocytes.

11 erism of recipient-derived and donor-derived leucocytes.

12 ely via its inhibitory effects on phagocytic leucocytes.

13 d to vascular endothelial cells and invading leucocytes.

14 mopoietic cells, including immune-modulating leucocytes, a prerequisite of the tolerance induction st

15 About 25% of the generated leucocytes acquired MHC class II and costimulatory molec

16 ors play a key role in the transmigration of leucocytes across the blood-brain barrier (BBB).

17 y contribute to the increased trafficking of leucocytes across the blood-brain barrier as seen in cer

18 c factors, since they are also implicated in leucocyte activation, angiogenesis, and antimicrobial fu

19 terized by reduced plasma leakage, decreased leucocyte adhesion and ameliorated lung pathology, culmi

20 ition of PATs attenuates barrier leakage and leucocyte adhesion induced by endothelial junction hyper

21 dep) display blunted barrier dysfunction and leucocyte adhesion, whereas leucocytes from these mice d

22 hages that have engulfed erythrocytes and/or leucocytes and can harbour Salmonella in mice.

23 e detection of HHV-7 DNA in peripheral blood leucocytes and donorrecipient CMV serostatus.

24 ounts of emerin of normal size were found in leucocytes and lymphoblastoid cell lines.

25 Thanks to phagocytic leucocytes and other host defenses, the vast majority of

26 vascular endothelial cells, and circulating leucocytes and platelets.

27 isease bound twice as many polymorphonuclear leucocytes and U937 cells as endothelial cells from unin

28 assessed HIMEC binding to polymorphonuclear leucocytes and U937 cells by means of an adhesion assay.

29 lood eosinophil count (<2% vs >/=2% of blood leucocytes) and whether or not patients had received inh

30 890) and telomere length in peripheral blood leucocytes, and assessed their associations with chronic

31 re regulated general metabolism processes in leucocytes, and miRNA altered in remission are involved

32 current study was to investigate whether dog leucocyte antigen (DLA) class II alleles and haplotypes

33 ansplant in the UK are sensitised with human leucocyte antigen (HLA) antibodies.

34 4 and SACM2L) and a thus far unnoticed human leucocyte antigen (HLA) class II pseudogene, termed HLA-

35 cell exhaustion, and downregulation of human leucocyte antigen (HLA) class II.

36 A human leucocyte antigen (HLA) distribution analysis was also p

37 the strongest signal deriving from the human leucocyte antigen (HLA) gene HLA-DQA1.

38 Genetic variation at the Human Leucocyte Antigen (HLA) genes is associated with many au

39 genetic defect, which is linked to the human leucocyte antigen (HLA) locus.

40 s been active debate about the role of human leucocyte antigen (HLA) matching in kidney allograft sur

41 L2 receptor gamma chain knockout (NSG) human leucocyte antigen (HLA)-DQ8 transgenic animals.

42 ls were used to evaluate the effect of human leucocyte antigen (HLA)-DR2 (DRB1*1501, DQB1*0602) on cl

43 Human leucocyte antigen (HLA)-G, an immunosuppressive molecule

44 ation, and de novo donor-specific anti-human leucocyte antigen antibodies (dnDSAs) have been associat

45 s with the DRB1 and DQB alleles of the human leucocyte antigen class II region.

46 ce of the role of environmental and nonhuman leucocyte antigen genetic factors in coeliac disease.

47 Multiple gene polymorphisms and human leucocyte antigen haplotype associations with primary sc

48 isms and ulcerative colitis associated human leucocyte antigen haplotypes are not associated with pri

49 which was indirectly supported by the human leucocyte antigen-Cw6 disease association.

50 1 psoriasis is strongly linked to the human leucocyte antigen-Cw6, recent genetic studies have sugge

51 Human leucocyte antigen-G (HLA-G) is a non-classical HLA class

52 urvivals of 65-75% are achievable with human leucocyte antigen-matched related and unrelated donors.

53 ed with comparable survival to that of human leucocyte antigen-matched URD transplantation in childre

54 nd resistance are associated with both human leucocyte antigen-related and unrelated genetic factors.

55 ptors that recognize aberrantly folded human leucocyte antigen.

56 atients with circulating antibodies to human leucocyte antigens (anti-HLA) are highly sensitised agai

57 t their differentiated progeny express human leucocyte antigens (HLAs) that will probably cause graft

58 nd no increase in the frequency of the human leucocyte antigens associated with narcolepsy.

59 ibutable to variants in genes encoding human leucocyte antigens, only about a quarter of reported her

60 While endothelial cells and leucocytes are widely accepted as critical players in th

61 ation can promote heart failure, positioning leucocytes as central protagonists and potential therape

62 immunoglobulin-like receptor B1 (LILRB1) or leucocyte-associated immunoglobulin-like receptor 1 (LAI

63 Enhanced leucocyte binding by HIMEC from chronically inflamed tis

64 We investigated whether this enhanced leucocyte binding is a primary or an acquired defect.

65 ammatory bowel disease--display an increased leucocyte-binding capacity in vitro.

66 ced pleurisy, dominated by polymorphonuclear leucocytes, but may aid resolution at the later, mononuc

67 xpression could readily be detected in blood leucocytes by PCR analysis in all control samples but no

68 Techniques involving radiolabelled leucocytes can pinpoint the site of inflammation.

69 CD45, the leucocyte common antigen, is a haemopoietic cell-specifi

70 The leucocyte common antigen-related receptor tyrosine phosp

71 ory of heart failure (OR, 1.43 [1.01-2.03]), leucocyte count </=72 hours after TAVI (OR, 1.05 [1.02-1

72 s 158 [25%] in the control group), decreased leucocyte count (103 [16%] vs 74 [20%]), fatigue (81 [13

73 ate analysis, means of parameters like total leucocyte count, urea, bilirubin, alanine transaminase,

74 iodontal therapy on arterial blood pressure, leucocyte counts, fibrinogen, tissue necrosis factor-a,

75 recombinant IL-1beta in primary head kidney leucocyte cultures and RTS-11 cells, a macrophage cell l

76 The gram stain and acridine-orange leucocyte cytospin test (AOLC) is rapid (30 min), inexpe

77 transcriptomic analysis of peripheral blood leucocytes defines two distinct sepsis response signatur

78 Leucocyte depletion studies confirmed that this differen

79 5-mC content was measured in leucocyte DNA by use of a combination of high-performanc

80 th was calculated by in-gel hybridisation to leucocyte DNA from 56 normal individuals aged 0-96 years

81 %5-mC was measured in leucocyte DNA from 775 cases and 397 controls.

82 leucocyte DNA were detected, we also tested leucocyte DNA from the individuals' fathers, and in one

83 ave shown in a large case-control study that leucocyte DNA hypomethylation is associated with increas

84 er mL, we detected Y-chromosome deletions in leucocyte DNA similar in location to those previously re

85 he two men in whom Y-chromosome deletions in leucocyte DNA were detected, we also tested leucocyte DN

86 By PCR, we tested leucocyte DNA, from 35 men who presented at infertility

87 Screening this library for binding to human leucocyte elastase identified sequences with a strong co

88 Human leucocyte elastase is known to have a substrate preferen

89 Testing of the human leucocyte elastase-selected sequences as inhibitors of p

90 isozymes in monocytes and polymorphonuclear leucocytes ex vivo.

91 Anx-1-/- polymorphonuclear leucocytes exhibited increased spontaneous migratory beh

92 When selected growth factors were added, leucocytes expressing CD45 were generated and released i

93 undamental role in the tissue recruitment of leucocytes following exposure to allergens.

94 0 expression in human cell lines and primary leucocytes following treatment with rhinovirus.

95 that the RNA sequences in high abundance in leucocytes from chronic granulocytic leukaemias differ q

96 dysfunction and leucocyte adhesion, whereas leucocytes from these mice did not show altered adhesive

97 cells, the interaction of the beta2 integrin leucocyte function-associated antigen-1 (LFA-1) with its

98 We assayed peripheral blood leucocyte global gene expression for a prospective disco

99 Comparison between 99mTc Infecton and leucocyte imaging gave sensitivities of 84% and 81%, and

100 ound that a subset of RIFINs binds to either leucocyte immunoglobulin-like receptor B1 (LILRB1) or le

101 by lipopolysaccharide (LPS) stimulated human leucocytes in order to provide an initial structure-acti

102 f up to about 3000 compared to the number of leucocytes in the blood.

103 at form virological synapses with uninfected leucocytes in the lymph node of living mice.

104 Specifically, OSM, expressed by CD45(+) leucocytes in the stromal vascular fraction, induced pho

105 endritic cells (DCs), recruited inflammatory leucocytes, including APCs in mice, and promoted antigen

106 arge vessel disease that is characterized by leucocyte infiltration and lipid deposition in the wall

107 e disease in MRL-lpr mice is associated with leucocyte infiltration into the choroid plexus, brain ce

108 Leucocyte infiltration with vascular leakage and express

109 promoting matrix destruction, angiogenesis, leucocyte infiltration, and apoptosis.

110 iated with a marked reduction in ICH-induced leucocyte infiltration, microglia/macrophage activation

111 negative breast cancer (TNBC) often exhibits leucocyte infiltrations that correlate with favorable pr

112 sion of proinflammatory molecules, decreased leucocyte inflammation, and significantly improved graft

113 le-1 (ICAM-1) functions via its ligands, the leucocyte integrins, in adhesion of immune cells to endo

114 ytokines seem able to attract HIV-1-infected leucocytes into the amniotic cavity and to increase repl

115 by the migration of HIV-1-infected maternal leucocytes into the amniotic cavity.

116 se interaction between endothelial cells and leucocytes is a key regulatory step in the inflammatory

117 n regulates responses by respiratory mucosal leucocytes isolated from nasal polyps.

118 icating genes involved in the 'regulation of leucocyte/lymphocyte activity' and also 'cytokine-mediat

119 active oxygen species from polymorphonuclear leucocytes may be potential inducers of the RprY regulon

120 te airway smooth muscle cell contraction and leucocyte migration and proliferation.

121 tic-like response: bronchial-alveolar lavage leucocyte numbers, Muc5ac and Muc5b mRNA levels, and Cla

122 OAT mRNA was isolated from peripheral blood leucocytes of 1 patient and analyzed.

123 to distinguish clearly the peripheral blood leucocytes of chronic granulocytic leukaemias from other

124 g a sensitive KIT mutation analysis of blood leucocytes or measurement of urinary histamine metabolit

125 genome-wide studies in ARDS use total blood leucocytes; our study is the first, to our knowledge, to

126 ecreased FMRP expression in peripheral blood leucocytes over the same repeat range, despite a slight

127 ion has been noted in human peripheral blood leucocytes (PBL).

128 -documented impairments in polymorphonuclear leucocyte (PMN) function.

129 Granulocyte [polymorphonuclear leucocyte (PMN)] migration to sites of infection and sub

130 CMV pp65 antigen positive polymorphonuclear leucocytes (PMNLs) per 200 000 cells previously reported

131 we demonstrated that blood polymorphonuclear leucocytes (PMNs) in ARDS are basally activated, and exh

132 mRNA from human polymorphonuclear neutrophil leucocytes (PMNs) was probed with cDNA encoding human sk

133 aired defense functions of polymorphonuclear leucocytes (PMNs), increased patient susceptibility to i

134 d RNAs of a variety of normal and neoplastic leucocyte populations showed that the RNA sequences in h

135 To compare peripheral blood leucocyte populations using flow cytometry at baseline a

136 epresenting the RNAs of normal and leukaemic leucocyte populations were sufficiently different to dis

137 before and after treatment, and in purified leucocyte populations.

138 pithelial barrier and may then interact with leucocytes, potentially inducing proinflammatory respons

139 or their ability to inhibit murine and human leucocyte proliferation and TNF-alpha secretion by lipop

140 Secretory leucocyte protease inhibitor (SLPI) is a 107-amino acid

141 clude PLC-gamma2, Syk, SH2-domain-containing leucocyte protein of 76 kDa (SLP-76), Lyn, linker for ac

142 NE and Cat G selective inhibitor, secretory leucocyte proteinase inhibitor, reduction of the enhance

143 hide core domain proteins, such as secretory leucocyte proteinase-1 (SLP-1), but the Trichuris protei

144 We used the mixed leucocyte reaction (MLR), stimulating one partner's peri

145 tor cells), cytochemical staining, and mixed leucocyte reactions to determine the functional capacity

146 novirus-induced ORMDL3 expression in primary leucocytes required cell-cell contact, and induction was

147 These hES-derived, MHC class II+ leucocytes resembled dendritic cells and macrophages, an

148 ing eosinophil counts of 2% or more of blood leucocytes respond better to inhaled corticosteroids tha

149 uantum yield (approximately 0.98), and human leucocyte-specific monoclonal antibodies (CD3, CD4, and

150 ese patients with those from a radiolabelled leucocyte study.

151 ich could favour the recruitment of distinct leucocyte subsets into the skin.

152 Leucocyte telomere length (LTL) shortening is associated

153 Mean leucocyte telomere length is a predictor of future coron

154 Our aim was to determine whether mean leucocyte telomere length is a predictor of the developm

155 Shorter leucocyte telomere lengths are associated with worse sur

156 estigate whether patients with various blood leucocyte telomere lengths had different overall surviva

157 Eosinophils are immunomodulatory leucocytes that contribute to the pathogenesis of Th2-dr

158 muscle use can stimulate muscle invasion by leucocytes that have the potential to increase tissue da

159 latelets and other cells (endothelial cells, leucocytes) that contribute to an inflammatory response,

160 o-immunized with their partners' mononuclear leucocytes to prevent spontaneous recurrent abortion.

161 AM-1 mediates adhesion and transmigration of leucocytes to the vascular endothelial wall, a step prop

162 remission dynamics of MS in peripheral blood leucocytes, to shed light on the molecular and regulator

163 g events play additional functional roles in leucocyte trafficking.

164 mutant resulted in reduced polymorphonuclear leucocyte transepithelial migration and mitogen-activate

165 rotein kinase pathways and polymorphonuclear leucocyte transepithelial migration associated with Shig

166 ORMDL3, HSPA5 and IFNB1 expression varied by leucocyte type and 17q21 genotype, with the highest expr

167 Anaplastic lymphoma kinase (Alk) and leucocyte tyrosine kinase (Ltk) were identified as "orph

168 of the activity of the sodium pump of human leucocytes was used to test each fraction for the presen

169 s from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6.

170 ukin 1 and cytokine mRNA in peripheral-blood leucocytes were not raised, but amounts of interleukin 1

171 inoma patients' peripheral blood mononuclear leucocytes were stimulated in vitro with autologous tumo

172 inant cells at 2 hours are polymorphonuclear leucocytes, whereas mononuclear cells dominate from 24 h

173 , followed by tissue destruction mediated by leucocytes which clinically cause significant destructio

174 lated by stimulation of isolated head kidney leucocytes with lipopolysaccharide (LPS).

175 also induced following stimulation of kidney leucocytes with lipopolysaccharide for 4 h.