ライフサイエンスコーパス: leucyl-tRNA synthetase

1 e mechanochemical motions in T. thermophilus leucyl-tRNA synthetase.

2 nate amino acids that can be misactivated by leucyl-tRNA synthetase.

3 he ser-tRNACAG and preventing binding of the leucyl-tRNA synthetase.

4 editing of mischarged tRNA similar to other leucyl-tRNA synthetases.

5 out mischarging by glycyl-, glutaminyl-, and leucyl-tRNA synthetases.

6 use HSPE71, Rat RhoGAP protein, S cerevisiae leucyl tRNA synthetase and S cerevisiae chromosome II OR

7 Binding of gold-labeled tRNA(Leu) places leucyl-tRNA synthetase and the bifunctional glutamyl-/pr

8 y a constitutive protein complex composed of leucyl-tRNA-synthetase and folliculin, which regulates m

9 ein, different mutations in Escherichia coli leucyl-tRNA synthetase are combined to unmask the pretra

10 of onychomycosis, inhibits yeast cytoplasmic leucyl-tRNA synthetase by formation of a stable tRNA(Leu

11 he collective motion in Thermus thermophilus leucyl-tRNA synthetase by studying the low frequency nor

12 gnment we have analyzed the Candida albicans leucyl-tRNA synthetase (CaLeuRS) gene (CaCDC60).

13 We present structures of leucyl-tRNA synthetase complexed with analogs of the dis

14 These mutations that altered or abolished leucyl-tRNA synthetase editing were introduced into comp

15 overcome this limitation, we have adapted a leucyl-tRNA synthetase from Methanobacterium thermoautot

16 n identified a mutation in the mitochondrial leucyl-tRNA synthetase gene (lrs-2) that impaired mitoch

17 Leucyl-tRNA synthetases have a hydrolytic active site th

18 d mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase: homozygous c.1565C>A (p.Thr522As

19 Human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) achieves high amino

20 ell, Bonfils et al. and Han et al. implicate leucyl-tRNA synthetase in this evolving story.

21 is activated by methionyl-, isoleucyl-, and leucyl-tRNA synthetases in vivo.

22 A point mutation in CP1 of class I leucyl-tRNA synthetase inactivates deacylase activity an

23 rving cells of leucine or treating them with leucyl-tRNA synthetase inhibitors did not elicit nuclear

24 ted that the transfer of human mitochondrial leucyl-tRNA synthetase into the cybrid cells carrying th

25 er the overexpression of human mitochondrial leucyl-tRNA synthetase (LARS2) in the cytoplasmic hybrid

26 Escherichia coli leucyl-tRNA synthetase (LeuRS) aminoacylates up to six d

27 Yeast mitochondrial leucyl-tRNA synthetase (LeuRS) binds to the bI4 intron a

28 c and editing activities of Escherichia coli leucyl-tRNA synthetase (LeuRS) demonstrate that the enzy

29 Leucyl-tRNA synthetase (LeuRS) has been identified as a

30 Leucyl-tRNA synthetase (LeuRS) has evolved an editing fu

31 Mitochondrial leucyl-tRNA synthetase (LeuRS) in the yeast Saccharomyce

32 Leucyl-tRNA synthetase (LeuRS) is a class I enzyme, whic

33 Leucyl-tRNA synthetase (LeuRS) is an essential RNA splic

34 In one case, Mycoplasma mobile leucyl-tRNA synthetase (LeuRS) is uniquely missing its e

35 Leucyl-tRNA synthetase (LeuRS) misactivates non-leucine

36 Leucyl-tRNA synthetase (LeuRS) performs dual essential r

37 Leucyl-tRNA synthetase (LeuRS) relies on its editing fun

38 this biocontrol agent targets A. tumefaciens leucyl-tRNA synthetase (LeuRS), an essential enzyme for

39 In leucyl-tRNA synthetase (LeuRS), editing activities that

40 Leucyl-tRNA synthetase (LeuRS), isoleucyl-tRNA synthetas

41 Leucyl-tRNA synthetase (LeuRS), isoleucyl-tRNA synthetas

42 a unique tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase (LeuRS), while the TM84-producer

43 thanogenesis, protein-modifying factors, and leucyl-tRNA synthetase (LeuRS).

44 synthetase (GluRS):tRNA(Glu) and an archaeal leucyl-tRNA synthetase (LeuRS):tRNA(Leu) complex.

45 lpha was found to form a stable complex with leucyl-tRNA synthetase (LeuRS; K(D) = 0.7 microM).

46 erminal domain extension is required by most leucyl-tRNA synthetases (LeuRS) for aminoacylation.

47 cluding a complex between prolyl-(ProRS) and leucyl-tRNA synthetases (LeuRS) in Methanothermobacter t

48 Aminoacylation and editing by leucyl-tRNA synthetases (LeuRS) require migration of the

49 Leucyl-tRNA synthetases (LeuRSs) have an essential role

50 Mycoplasma leucyl-tRNA synthetases (LeuRSs) have been identified in

51 ing pocket within the editing active site of leucyl-tRNA synthetases (LeuRSs).

52 ulting from cancer-associated MTOR mutations.Leucyl-tRNA synthetase (LRS) is a leucine sensor of the

53 Leucyl-tRNA synthetase (LRS) is known to function as leu

54 carboxy-terminal domain (Cterm) of human mt-leucyl tRNA synthetase rescues the pathologic phenotype

55 cid editing active site for Escherichia coli leucyl-tRNA synthetase resides within the CP1 domain tha

56 hreonine-rich region of the Escherichia coli leucyl-tRNA synthetase's CP1 domain that is hypothesized

57 tational analysis within yeast mitochondrial leucyl-tRNA synthetase showed that the enzyme has mainta

58 4-Azaleucine, a competitive inhibitor of leucyl-tRNA synthetase, surprisingly triggered the heat

59 ed conformational changes of T. thermophilus leucyl-tRNA synthetase upon substrate binding and analyz

60 red the refolding of the human mitochondrial leucyl-tRNA synthetase variant H324Q to that of wild typ

61 be aminoacylated by the human mitochondrial leucyl-tRNA synthetase, we examined the aminoacylation k

62 The yeast mitochondrial leucyl-tRNA synthetase (ymLeuRS) performs dual essential