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1 by integrin-dependent sickle-red blood cell-leukocyte adhesion.
2 m by which LA1-activated CD11b/CD18 mediates leukocyte adhesion.
3 and is critical for firm integrin-dependent leukocyte adhesion.
4 t captures CTCs while minimizing nonspecific leukocyte adhesion.
5 LFA-1 also mediates leukocyte adhesion.
6 of mobility for the onset of LFA-1 mediated leukocyte adhesion.
7 the inhibition of exocytosis, and suppresses leukocyte adhesion.
8 othelium (P = 0.03) matching the increase in leukocyte adhesion.
9 lammatory signals with those associated with leukocyte adhesion.
10 microglial activation, and reduced cerebral leukocyte adhesion.
11 ed ICAM-1 in endothelial cells (EC) promotes leukocyte adhesion.
12 ation into plaques through platelet-mediated leukocyte adhesion.
13 s an important regulator of CX3CL1-dependent leukocyte adhesion.
14 a preceding activation step to trigger firm leukocyte adhesion.
15 for antithrombotic therapy based on blocking leukocyte adhesion.
16 on and digestion to regulating bacterial and leukocyte adhesion.
17 lar adhesion molecule-1 dependent intestinal leukocyte adhesion.
18 finity triggering mediates chemokine-induced leukocyte adhesion.
19 tion of HC-HA cable structures and abolishes leukocyte adhesion.
20 ry factor, which inhibits integrin-dependent leukocyte adhesion.
21 the markers of thrombosis, inflammation, and leukocyte adhesion.
22 onal change in beta2 integrins, facilitating leukocyte adhesion.
25 ional biology: a mechanics-based modeling of leukocyte adhesion (adhesive dynamics) and signal transd
26 and partly prevented increases in VCAM-1 and leukocyte adhesion after treatment with tumour necrosis
27 creased permeability, ICAM-1 expression, and leukocyte adhesion, all of which are features of an infl
28 ated a crucial role for CatG during arterial leukocyte adhesion, an effect not found during venular a
29 uorescence microscopy, we observed excessive leukocyte adhesion and accelerated atherosclerotic plaqu
33 clerosis in ApoE(-/-) mice, there is reduced leukocyte adhesion and decreased CD18 expression on Gr1(
34 9)/L platelets, showing reduced signaling in leukocyte adhesion and diapedesis and increased compleme
35 DPA and RvD5n-3 DPA decreased the extent of leukocyte adhesion and emigration following ischemia-rep
36 ntified role for Panx1 channels in promoting leukocyte adhesion and emigration through the venous wal
37 ade body secretion, and in the regulation of leukocyte adhesion and extravasation during inflammation
38 ion in the genetic absence of Coro1A impairs leukocyte adhesion and extravasation in inflamed cremast
39 muscle venules revealed severely compromised leukocyte adhesion and extravasation in MK(-/-) mice com
40 control endothelial cell (EC) permeability, leukocyte adhesion and inflammation are pivotal for athe
43 ligands and their ability to intervene with leukocyte adhesion and migration across brain endothelia
44 CX3CR1 is a chemokine receptor involved in leukocyte adhesion and migration and hence a mediator of
45 egment of the microvasculature that supports leukocyte adhesion and migration expands through remodel
47 l antibody against alpha4 integrin, inhibits leukocyte adhesion and migration into inflamed tissue.
48 The finding that Cdk inhibitors can block leukocyte adhesion and migration may expand the clinical
49 t human fetal HSCs employ mechanisms used in leukocyte adhesion and migration to mediate HSC self-ren
52 dothelial activation manifested as increased leukocyte adhesion and plasma extravasation in response
53 ta2-integrin activation is indispensable for leukocyte adhesion and recruitment to sites of infection
55 new role of fibrinogen in integrin-mediated leukocyte adhesion and suggest that this mechanism may p
56 tify alpha 4 integrin/CD49d as a mediator of leukocyte adhesion and the resultant early signature abn
57 protein I (beta2GPI) induce endothelial cell-leukocyte adhesion and thrombus formation via unknown me
58 ould be used as a therapeutic tool to reduce leukocyte adhesion and thus reduce neuroinflammation.
59 or investigation of lymphatic involvement in leukocyte adhesion and trafficking during the immune res
60 the effects of hemodynamics and cytokines on leukocyte adhesion and trans-endothelial migration (TEM)
61 t human JAM-C to determine its role in human leukocyte adhesion and transendothelial cell migration u
62 ion of endothelial ABPs to the regulation of leukocyte adhesion and transendothelial migration remain
65 l in vivo, elastic laminae were resistant to leukocyte adhesion and transmigration compared with the
66 synthase and fibrinolytic activity, decrease leukocyte adhesion and transmigration, and enhance resis
69 F-induced proliferation and thrombin-induced leukocyte adhesion and triggers a STAT3-dependent increa
70 dase is positively correlated with increased leukocyte adhesion and vascular leakage in diabetes and
73 is, cell growth and apoptosis, angiogenesis, leukocyte adhesion, and cytokine activation and inhibiti
74 hamber protein concentration, retinal vessel leukocyte adhesion, and protein leakage were measured 24
76 cells is essential for platelet aggregation, leukocyte adhesion, and transmigration through endotheli
77 a-AR stimulation can promote both SS RBC and leukocyte adhesion as well as vaso-occlusion, suggesting
79 sing IVM, we could detect instant changes in leukocyte adhesion behavior in the synovial vessels of t
80 ies in the murine inflamed microcirculation (leukocyte adhesion being the readout) and in skin traffi
81 , the retinas were extracted and assayed for leukocyte adhesion; blood-retinal barrier breakdown; VEG
82 hoG by small interfering RNA does not affect leukocyte adhesion but decreases cup formation and inhib
83 tyrosine phosphatase 1 (Shp1) show increased leukocyte adhesion, but the interpretation of these data
84 of the immunoglobulin superfamily, supports leukocyte adhesion by binding alpha4beta1 integrins and
85 3 cells, suggesting that these miRs regulate leukocyte adhesion by modulating the expression of adhes
88 These data provide unique insights in the leukocyte adhesion cascade and the potential for time-ba
91 tion in vivo and add additional steps to the leukocyte adhesion cascade that supports leukocyte traff
92 be used for real-time studies of the entire leukocyte adhesion cascade, including rolling, adhesion,
93 N-glycans contributing to all aspects of the leukocyte adhesion cascade, O-glycans only being importa
96 In view of the capacity of FKN to mediate leukocyte adhesion, chemoattraction, and transmigration,
97 neally) resulted in a three-fold increase in leukocyte adhesion, compared with ischemia/reperfusion a
100 s in this disappearance, a dog having canine leukocyte adhesion deficiency (CLAD) or CLAD dogs who ha
103 umans, mutations in beta(2) integrin lead to leukocyte adhesion deficiency (LAD) syndrome and mutatio
104 activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans,
109 autosomal recessive disease characterized by leukocyte adhesion deficiency as well as severe neurolog
110 ontrasts with the phenotype seen in type III leukocyte adhesion deficiency caused by the absence of k
111 nd identify CF as a new, cell type-selective leukocyte adhesion deficiency disease, providing new ins
112 The protein kindlin 3 is mutated in the leukocyte adhesion deficiency III (LAD-III) disorder, le
116 SCs, and thus lack of CD18 expression in the leukocyte adhesion deficiency patients may predispose th
117 ivation on leukocytes is the hallmark of the leukocyte adhesion deficiency syndrome in humans, charac
118 f young dogs with the genetic disease canine leukocyte adhesion deficiency that were treated with a n
120 e the contribution of CD18 on neutrophils to leukocyte adhesion deficiency type I (LAD-I), a complex
121 se), severe congenital neutropenia (SCN) and leukocyte adhesion deficiency type I confer a predisposi
123 hypofucosylated in PMNs from a patient with leukocyte adhesion deficiency type II, suggesting that i
124 lts imply that the immunodeficiency found in leukocyte adhesion deficiency type III patients, in addi
125 accumulation of HSPCs in the circulation of leukocyte adhesion deficiency type III patients, who lac
126 hat is mutated in the rare genetic disorder, leukocyte adhesion deficiency type III, a disorder chara
127 n-3 is mutated in the rare genetic disorder, leukocyte adhesion deficiency type III, which is charact
129 enital origin (e.g., congenital neutropenia, leukocyte adhesion deficiency, and Chediak-Higashi syndr
130 cell activity is impaired, but not absent in leukocyte adhesion deficiency, may lead to the developme
131 which die perinatally of severe bleeding and leukocyte adhesion deficiency, mice expressing as little
135 adhesion deficiency-I; prenatal diagnosis of leukocyte adhesion deficiency-I; and association of auto
136 e adhesion deficiency-I; transplantation for leukocyte adhesion deficiency-I; prenatal diagnosis of l
137 herapy for chronic granulomatous disease and leukocyte adhesion deficiency-I; transplantation for leu
140 Patients with Glanzmann thrombasthenia or Leukocyte Adhesion Deficiency-III syndrome (LAD-III or L
144 E) abolished the inhibitory effect of gAd on leukocyte adhesion, demonstrating the obligatory role of
146 electin, ICAM-1, and EphB4 and were sites of leukocyte adhesion during lipopolysaccharide-induced acu
152 molecules, including interleukin (IL)-6, the leukocyte adhesion factor ICAM1, and chemokines that att
154 explain the shear threshold effect, in which leukocyte adhesion goes through a maximum with increasin
161 eceptors in endothelial cells also increased leukocyte adhesion in mesenteric venules and increased t
163 rteriogenesis, thrombosis, inflammation, and leukocyte adhesion in patients with intermittent claudic
165 Insulin decreased VCAM-1 expression and leukocyte adhesion in quiescent tumour endothelial cells
166 1INH significantly inhibit selectin-mediated leukocyte adhesion in several in vitro and in vivo model
167 This article discusses the importance of leukocyte adhesion in sickle cell disease, and how this
168 ]-3-methyl-cyclohexanol), greatly attenuated leukocyte adhesion in surface pial vessels and in deep a
172 d protein content in the aqueous fluid, firm leukocyte adhesion in the retinal vessels, and the numbe
177 pproximately 33 mumol) mitigated LPS-induced leukocyte adhesion in WT and AnxA1-null animals without
178 h soluble fibrinogen exerts its influence on leukocyte adhesion indicated that it did not block integ
179 studied endothelial permeability, intravital leukocyte adhesion, involvement of the Akt/WNT/beta-cate
187 platelet dysfunction in addition to impaired leukocyte adhesion, is now known to be due to absence of
188 m from obese mice expressed higher levels of leukocyte adhesion markers and lower levels of cell-cell
189 ignificantly increased the expression of the leukocyte adhesion markers LFA-1 and VLA-4, consistent w
192 macrophage-1 antigen complex, which mediates leukocyte adhesion, migration and phagocytosis as part o
193 and functions in diverse capacities such as leukocyte adhesion, migration, and cell survival on liga
194 dose of natalizumab, an antibody against the leukocyte adhesion molecule alpha4 integrin, in patients
195 this report, we have determined that the EC-leukocyte adhesion molecule E-selectin is a key target f
197 irectly suppressed endothelial activation of leukocyte adhesion molecule expression and inflammation.
199 ical surface, where JAM-A played a role as a leukocyte adhesion molecule participating in transendoth
202 observed elevated expression of endothelial leukocyte adhesion molecule-1, a human glaucoma marker,
204 ulatory role in cytokine induction of the EC-leukocyte adhesion molecules (ELAM) E-selectin and vascu
206 eta2 integrins (CD11/CD18) are heterodimeric leukocyte adhesion molecules expressed on hematopoietic
209 t, Rho GTPases affect the expression of some leukocyte adhesion molecules on endothelial cells, such
211 esion, and extravasation by up-regulation of leukocyte adhesion molecules such as E-selectin and P-se
212 e-inducible, NF-kappaB-dependent endothelial-leukocyte adhesion molecules that participate in the leu
213 tigated the role of p75 in TNF-alpha-induced leukocyte adhesion molecules using cultured ECs derived
215 ir ability to regulate the expression of key leukocyte adhesion molecules, on both leukocytes and end
216 capillaries enlarged into venules expressing leukocyte adhesion molecules, sprouting angiogenesis and
217 that the phenolic content of RW may modulate leukocyte adhesion molecules, whereas both ethanol and p
218 T cells (Tn) are expanded in mice that lack leukocyte adhesion molecules, which have neutrophilia an
219 associated with endothelial upregulation of leukocyte adhesion molecules, which persist even after i
221 or IL-6, and their retinas were analyzed for leukocyte adhesion or for the expression and localizatio
222 a(2+)]i in endothelial cells does not affect leukocyte adhesion or locomotion but selectively blocks
225 ndogenous inhibitors, as well as the role of leukocyte adhesion-promoting molecules) has provided new
227 matory markers, neutrophil chemoattractants, leukocyte adhesion proteins, and matrix metalloproteases
230 We report that in addition to supporting leukocyte adhesion, provision of specific substrate to V
231 shear stress responses, and TNFalpha-induced leukocyte adhesion rates characteristic of arterial endo
232 y increases in endothelial expression of the leukocyte adhesion receptor E-selectin and in microvascu
236 Pases are activated by engagement of several leukocyte adhesion receptors and contribute to both earl
237 lls (LECs), leading to expression of the key leukocyte adhesion receptors intercellular adhesion mole
240 tivity C-reactive protein, osteopontin), and leukocyte adhesion (soluble vascular cell adhesion molec
241 addressed this problem, two key features of leukocyte adhesion, such as cell deformation and rolling
242 n endothelial cells and, in turn, to augment leukocyte adhesion, thus exacerbating S1P-mediated proad
243 chronic inflammatory disease associated with leukocyte adhesion to and extravasation through vascular
245 a inhibition in vivo substantially decreased leukocyte adhesion to brain endothelium under inflammato
249 ich SS RBCs act via LW and CD44 to stimulate leukocyte adhesion to endothelium, and suggest that RBC
252 is study investigated the regulation of firm leukocyte adhesion to human brain endothelium by two dif
253 igation rapidly activated integrin-dependent leukocyte adhesion to immobilized ICAM-1 and fibronectin
254 in multiple leukocyte populations, impaired leukocyte adhesion to inflamed vessels, and accumulation
256 ation of AnxA1(2-50) markedly reduced (>60%) leukocyte adhesion to postcapillary venules in wild type
257 e blockade of NAD(P)H oxidase in turn blocks leukocyte adhesion to retinal vessels during diabetes an
258 tent with these findings, we found increased leukocyte adhesion to sdc-1 knock-out endothelial cells
259 rst description of a mechanism that prevents leukocyte adhesion to the endothelium by a parasite and
263 dose-dependently inhibited TNF-alpha-induced leukocyte adhesion to the murine cremasteric arterioles
265 ET-1-treated PbN-infected mice displayed leukocyte adhesion to the vascular endothelia and petech
266 ology of diabetic retinopathy is mediated by leukocyte adhesion to the vascular endothelium of the di
271 dition of heavy chains to HA cables enhanced leukocyte adhesion to these cables, but it also had seve
273 to nude mice promotes both SS RBC and murine leukocyte adhesion to vascular endothelium in vivo.
277 nd hemorrhagic shock did not further amplify leukocytes adhesion to intestinal venules compared with
278 oxemia and hemorrhagic shock did not amplify leukocytes adhesion to the endothelium further than eith
279 Furthermore, hemorrhagic shock triggered leukocytes adhesion to the venular endothelium to the sa
281 y for rapid activation of integrin-dependent leukocyte adhesion, triggered by toll-like receptor (TLR
282 the essential role for TXNIP in mediating EC-leukocyte adhesion under d-flow, as well as define a nov
286 ppressed the LPS-induced increase in retinal leukocyte adhesion; vascular leakage; NF-kappaB, HIF-1al
287 r contributed to activation of NF-kappaB and leukocyte adhesion via the EC induction of intercellular
294 ferase FUT9 played an important role because leukocyte adhesion was reduced by 50-60% in FUT9-HL-60,
296 expression on retinal neovascularization and leukocyte adhesion were abolished in mice lacking TNF-al
298 hyaluronan production or hyaluronan-mediated leukocyte adhesion when treated with the viral mimic pol
299 rolling phase resulting in the transition to leukocyte adhesion, which appear to contribute to chemok
300 tion of CatG specifically abrogated arterial leukocyte adhesion without affecting myeloid cell adhesi
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