ライフサイエンスコーパス: leukocytosis

1 swelling at the site, purulent drainage, and leukocytosis).

2 with lung or colorectal cancer often exhibit leukocytosis.

3 smell, peri-wound erythema, hypotension, and leukocytosis.

4 tion (e.g., serum elastase) accompanies this leukocytosis.

5 s (45%) required either GO or idarubicin for leukocytosis.

6 r in mice, characterized by splenomegaly and leukocytosis.

7 despite the expected induction of peripheral leukocytosis.

8 with fever, arthralgias, conjunctivitis, and leukocytosis.

9 valuable in the evaluation of posttransplant leukocytosis.

10 30% (14/47) of the patients never developed leukocytosis.

11 hritis, granulomatous hepatitis, anemia, and leukocytosis.

12 tested, while causing no adverse symptoms or leukocytosis.

13 E, except for the low levels of BALP and the leukocytosis.

14 larization or obesity-induced adipose tissue leukocytosis.

15 blood myeloid cells in patients with febrile leukocytosis.

16 baboons developed illness (with 1 death) and leukocytosis.

17 as well as the chemokine CXCL12, leading to leukocytosis.

18 Laboratory tests were remarkable for leukocytosis.

19 tive protein level (127 mg/L [1209 nmol/L]), leukocytosis (13 800/mm(3)), and microcytic anemia (hemo

20 r than that for patients who did not develop leukocytosis (2,100 cells/microL; range, 500 to 5,400 ce

21 riate Cox proportional hazards models showed leukocytosis (2.85 [hazard ratio]; P = .02), hypoalbumin

22 ) and significantly better in the absence of leukocytosis (37% v 8%; P = .01); JAK2V617F or cytogenet

23 Leukocytosis (53%) and fever (34%) were the most common

24 the underlying mechanisms of heparin-induced leukocytosis, a side effect occurring in 0.44% of patien

25 osis in hypercholesterolemic mice, displayed leukocytosis, a transplantable myeloproliferative disord

26 Leukocytosis affects CHD through multiple pathologic mec

27 mouse had significantly increased peritoneal leukocytosis after intraperitoneal challenge with thiogl

28 Because hydroxyurea also reduces leukocytosis, an understanding of the impact of this tre

29 27% of the patients and was associated with leukocytosis and a high percentage of bone marrow blast

30 ection of Ptx in mice elicits a long-lasting leukocytosis and a progressive increase in circulating c

31 G-CSF produced a dose-dependent neutrophil leukocytosis and a proportional increase in oxidase acti

32 connect expansion of these populations with leukocytosis and accelerated atherosclerosis.

33 Leukocytosis and activated monocytes are also observed i

34 a dominant-negative p53 construct developed leukocytosis and blastic infiltration of lymph nodes, sp

35 s and CD34(+) HSPCs that was associated with leukocytosis and central nervous system infiltration, bo

36 The aCML defining features of leukocytosis and circulating myeloid precursors, but not

37 pound mutation was associated with increased leukocytosis and disease progression of the patient.

38 rosol exposure, as determined by reduced BAL leukocytosis and eosinophilia, decreased tissue inflamma

39 Three of the four patients presented with leukocytosis and eosinophilia; their leukemia cells carr

40 Lsc-deficient mice have a peripheral leukocytosis and extramedullary hematopoiesis, demonstra

41 Leukocytosis and hemoconcentration were noted in both ca

42 t a chronic inflammatory state manifested by leukocytosis and increased circulating levels of proinfl

43 18, which lack all four CD11 integrins, have leukocytosis and increased susceptibility to bacterial i

44 Novel disease-related determinants such as leukocytosis and JAK2V617F mutational status and/or muta

45 Lab work was significant for leukocytosis and lactic acidosis.

46 IL-10 modestly attenuated neutrophilic leukocytosis and neutrophil degranulation (plasma concen

47 Laboratory evaluation was notable for leukocytosis and neutrophilia.

48 , whereas hematopoietic loss of Ptch2 drives leukocytosis and promotes LKS maintenance and replating

49 that MLL-ENL fusion is sufficient for lethal leukocytosis and proof of genome integrity comes from ge

50 LPS-induced ALI, as indicated by alveolar leukocytosis and protein leak, inhibition of surfactant

51 acute wounds that fail to heal are excessive leukocytosis and reduced matrix deposition.

52 In conclusion, both leukocytosis and renal failure are useful predictors, al

53 mmatory response and modulate the subsequent leukocytosis and secondary tissue damage.

54 p40 expression (IL-12p40(-/-)) resulted in a leukocytosis and splenomegaly that was significantly les

55 tion in nasopharyngeal washes and monitoring leukocytosis and symptoms.

56 s RA and arsenic trioxide is associated with leukocytosis and the RA syndrome.

57 n result in stimulation of both neutrophilic leukocytosis and the release of immature granulocytic po

58 Leukocytosis and thrombocytosis were also detected in in

59 the lung, attributable in part to background leukocytosis and to intravascular sequestration.

60 b72F+AS01B induced better protection against leukocytosis and weight loss, suggesting that the polypr

61 Elevated leukocyte cell numbers (leukocytosis), and monocytes in particular, promote athe

62 mic inflammatory response syndrome of fever, leukocytosis, and a hyperdynamic state is common in trau

63 ormal bone remodeling, elevated CRP level or leukocytosis, and a neutrophilic infiltrate on skin biop

64 otension, edema, hemoconcentration, profound leukocytosis, and absence of fever.

65 ions (arthritis, splenomegaly, hepatomegaly, leukocytosis, and acute-phase reaction) (P<0.01) in grou

66 ith all-trans RA is commonly associated with leukocytosis, and approximately 50% of patients develop

67 arked hepatosplenomegaly, myeloid dysplasia, leukocytosis, and biphenotypic surface markers.

68 was a marked reduction in TNF-alpha levels, leukocytosis, and brain pathology.

69 iated with the APL differentiation syndrome, leukocytosis, and electrocardiographic abnormalities.

70 e syndrome criteria (tachycardia, tachypnea, leukocytosis, and fever) in surgical ICU patients for IC

71 until 2 days after the resolution of fever, leukocytosis, and ileus, with a maximum of 10 days of th

72 d stage, central nervous system involvement, leukocytosis, and LDH >3 times the upper limit of normal

73 acilli from the cerebrospinal fluid, reduced leukocytosis, and less pathology of the brain and lungs

74 vels of tumor necrosis factor-alpha , higher leukocytosis, and more-severe clinical manifestations.

75 tive disease, characterized by splenomegaly, leukocytosis, and myeloid hypercellularity, which progre

76 Nonspecific symptoms included fever, leukocytosis, and neurologic abnormalities.

77 al pathology findings included coagulopathy, leukocytosis, and profound liver destruction as indicate

78 which is characterized by thrombocytopenia, leukocytosis, and rapid onset of respiratory distress ca

79 igen test result, a vaginal pH >4.5, vaginal leukocytosis, and recurrent (vs initial) T. vaginalis in

80 e CDI suggested by recent guidelines (fever, leukocytosis, and renal failure), we used the database o

81 tion of BCR-ABL resulted in neutrophilia and leukocytosis, and the mice became moribund within 29 to

82 Higher bilirubin, coagulopathy, leukocytosis, and thrombocytopenia were independently as

83 risk factors for survival include older age, leukocytosis, and thrombosis, whereas JAK2 mutation in E

84 s characterized in part by recurrent fevers, leukocytosis, anemia, and elevated acute phase proteins

85 ead, patients show progressive organomegaly, leukocytosis, anemia, and thrombocytosis.

86 In many cases, the mechanisms underlying leukocytosis are not known.

87 , including immunodeficiency, and persistent leukocytosis are risk factors for radiological recurrenc

88 Although causes of acute leukocytosis are well-described, chronic environmental d

89 LFA-1-deficient mice exhibit leukocytosis but do not develop spontaneous infections,

90 Stable patients with leukocytosis, but without fever or documented infections

91 ng of onset and awareness of the patterns of leukocytosis can be valuable in the evaluation of posttr

92 ears of life (dactylitis, severe anemia, and leukocytosis) can help to predict the possibility of sev

93 r expression of vIL-10 significantly reduced leukocytosis, cartilage matrix degradation, and levels o

94 Double deficiency yields an extreme leukocytosis characterized by decreased neutrophil turno

95 eloping anemia, thrombocytopenia, and marked leukocytosis compared with other subtypes.

96 lacking non-neuronal serotonin, showed mild leukocytosis compared with wild-type (WT), primarily dri

97 MI-associated blood leukocytosis correlates inversely with patient survival,

98 flow of leukocytes to inflamed tissues, and leukocytosis correlates with cardiovascular mortality.

99 est that leukocytes may play a role, because leukocytosis correlates with clinical severity and early

100 f physiological responses including a marked leukocytosis, disruption of glucose regulation, adjuvant

101 area and reduced lesion size without causing leukocytosis, dry eye, hair loss, or a reduced life span

102 Sustained leukocytosis, due to an increase in neutrophils counts,

103 as well as low-risk patients who experienced leukocytosis during induction.

104 e, the doubly deficient mice present extreme leukocytosis, elevated cytokine levels, and alterations

105 Within minutes of trauma, a comprehensive leukocytosis, elevated serum pro- and anti-inflammatory

106 The fourth patient had leukocytosis, eosinophilia, and a t(5;12) translocation

107 features of MPNs, including thrombocytosis, leukocytosis, Epo-independent colony formation, characte

108 L disease was characterized by splenomegaly, leukocytosis, extramedullary hematopoiesis (EMH) in sple

109 ower incidence of marked anemia (31% v 39%), leukocytosis greater than 25 x 10(9)/L (9% v 13%), and b

110 Twenty patients (50%) had leukocytosis (> 10,000 WBC/microL) during induction ther

111 In summary, leukocytosis has been consistently shown to be an indepe

112 lasm characterized by sustained neutrophilic leukocytosis, hepatosplenomegaly and bone marrow granulo

113 temic inflammation (anemia, thrombocytopenia leukocytosis, high erythrocyte sedimentation rate, eleva

114 urine TNF-alpha, as demonstrated by high CSF leukocytosis, high protein accumulation, severe meningea

115 lude abdominal pain, watery diarrhea, fever, leukocytosis, hypoalbuminemia, and hypovolemia.

116 ligand deficiency is distinguished by blood leukocytosis, impaired leukocyte extravasation in inflam

117 n beta2 subunit of CD11/CD18 integrins, have leukocytosis, impaired transendothelial neutrophil emigr

118 Fifty consecutive episodes of leukocytosis in 47 liver transplant recipients were pros

119 hemokines may be important in the control of leukocytosis in inflammatory disorders of the central ne

120 While investigating the source of leukocytosis in mice, we discovered that stress activate

121 -) mice and show that, apart from anemia and leukocytosis in older mice, the production of mature blo

122 cent confidence interval, 1.14 to 5.33), and leukocytosis in the absence of infection (relative risk,

123 reported that dactylitis, severe anemia, and leukocytosis in very young children with sickle cell dis

124 ditional vcam-1-deficient mice revealed mild leukocytosis, including elevated immature B cell numbers

125 tivariate analysis, severe thrombocytopenia, leukocytosis, increasing marrow blast percentage, unfavo

126 djustment for presence of abscess, fever, or leukocytosis; infection size; diabetes; patient age; and

127 L-12, and transfusion need; IL-2R, IL-8, and leukocytosis; IP-10 and thrombocytopenia; HGF, MIG, IL-1

128 Leukocytosis is associated with increased cardiovascular

129 Leukocytosis is associated with the proliferation of hem

130 ioxide, with minimal chemotherapy to control leukocytosis, is very effective therapy for newly diagno

131 Correlations are emerging between leukocytosis, JAK2(V617F) mutation, BM fibrosis, and dif

132 as found for tenosynovitis (lambda(s) 29.5), leukocytosis (lambda(s) 25), rheumatoid factor (lambda(s

133 at the loss of Ccr7 results in a significant leukocytosis, leading to hypercellularity within the CNS

134 article-enabled in vivo RNAi mitigated blood leukocytosis, limited inflammation in the ischemic heart

135 racterized included impaired erythropoiesis, leukocytosis, loss of early progenitor cells in the bone

136 R, 1.4 [95% CI, 1.1-2.0]), nor does isolated leukocytosis (LR, <1.7).

137 ent monocytosis and is often associated with leukocytosis, lymphoproliferation, and autoimmune phenom

138 accounted for 28% (14/50) of the episodes of leukocytosis; median time to onset was 25 days after tra

139 ng elevation in hemoglobin level/hematocrit, leukocytosis, megakaryocyte hyperplasia, extramedullary

140 istent with an atypical MPN characterized by leukocytosis, monocytosis, splenomegaly, and progressive

141 counting methods do not distinguish between leukocytosis, neutrophil sequestration, and activation.

142 with significantly greater reticulocytosis, leukocytosis, neutrophilia and thrombocytosis, marked ex

143 activation and develop a MPN-phenotype with leukocytosis (neutrophils and monocytes), strong progeni

144 2% (11/50) of the episodes, a characteristic leukocytosis occurred 7-14 days after transplantation (i

145 Leukocytosis of more than 30 x 10(9)/L was found in 26%,

146 dies are needed to assess the true impact of leukocytosis on CHD, compare it with other inflammatory

147 She had no evidence of leukocytosis or anemia and no symptoms of early satiety,

148 fter LT and was infrequently associated with leukocytosis or fever.

149 Infection was defined as leukocytosis or leukopenia, with a positive culture requ

150 The majority of patients with leukocytosis or thrombocytosis at baseline (n = 28 and n

151 r-related sepsis (CRS) was defined as fever, leukocytosis, or hypotension which resolved with cathete

152 graphic infiltrate with at least 2 of fever, leukocytosis, or purulent sputum increases the likelihoo

153 se of postoperative (P < 0.01) or infectious leukocytosis (P < 0.05).

154 ms and signs, with more vomiting (P = .003), leukocytosis (P = .003), and blood in the stool (P = .00

155 ldren were less likely than controls to have leukocytosis (P<.001) and more likely to have isolates w

156 Prevalent at diagnosis were leukocytosis, peripheral blast exceeding marrow blast pe

157 crease as viral latency increased and as the leukocytosis phase of the disease progressed.

158 al or laboratory parameter, including fever, leukocytosis, pleocytosis, or CSF protein and glucose, c

159 sia, and marked thrombocythemia, but without leukocytosis, polycythemia, or marrow fibrosis, displayi

160 erium bovis Ravenel intracisternally induced leukocytosis (predominantly mononuclear cells), high pro

161 NF-alpha in the CSF in association with high leukocytosis, protein accumulation, and severe meningeal

162 use severe disease, manifested as pronounced leukocytosis, pulmonary hypertension, and even death.

163 Deaths relate to leukocytosis, pulmonary hypertension, and pneumonia.

164 ents with a clinical diagnosis of PN (fever, leukocytosis, purulent sputum, and new or changing infil

165 All 8 patients developed leukocytosis (range, 14.5-27.6 x 10(9)/L) with eosinophi

166 sis accompanied by features of MF, including leukocytosis, reduced hematocrit, splenomegaly, and incr

167 Leukocytosis refers to an increase in leukocyte count ab

168 We conclude that heparin-induced leukocytosis requires glucosamine 6-O-sulfation and is c

169 cytotoxic therapy was administered, and the leukocytosis resolved in all cases.

170 ceptibility to the lethal effects of PTX and leukocytosis response were observed.

171 ce susceptibility to the lethal effects, the leukocytosis response, disruption of glucose regulation,

172 This leukocytosis resulted in a significant enhancement of le

173 veloping 24 to 40 h postexposure followed by leukocytosis resulting from a high percentage of neutrop

174 ultiple selectins display varying degrees of leukocytosis, resulting in part from alterations in leuk

175 Quantification of adipose tissue leukocytosis revealed that elimination of Chop during ob

176 (HDL) suppressed the LSK population, reduced leukocytosis, reversed the myeloproliferative disorder,

177 Leukocytosis (risk ratio [RR], 2.29; 95% confidence inte

178 The modest leukocytosis seen during paclitaxel cycles was attributa

179 However, after controlling for age, leukocytosis, sex, laparoscopic approach, and perforatio

180 ML-RAR alpha leukemias were characterized by leukocytosis, similar to human APL with FLT3 mutations.

181 e disorder characterized by myeloid-dominant leukocytosis, splenomegaly, and an increase of hematopoi

182 ythematosus (SLE)-like disease that included leukocytosis, splenomegaly, hypergammaglobulinemia, anti

183 F/P(+) HSC/Ps (IL-5Tg-F/P) developed intense leukocytosis, strikingly high eosinophilia, and eosinoph

184 Leukocytosis strongly correlated with the adrenaline res

185 anifestations included intense inflammation, leukocytosis, synovial hypertrophy and hyperplasia, and

186 PT promoted colonization, leukocytosis, T cell phenotypic changes, systemic pathol

187 SFBL had more severe cecal inflammation and leukocytosis than TG SHAM controls.

188 unknown link between insulin sensitivity and leukocytosis that can affect the predisposition to ather

189 rmosets suggestive of thrombosis, as well as leukocytosis that consisted mostly of granulocytes.

190 epducins selective for CXCR4 cause a massive leukocytosis that does not affect survival.

191 he loss of Ccr7 resulted in an immediate pan-leukocytosis that remained elevated throughout the infec

192 for mortality, like renal insufficiency and leukocytosis, the network identified laboratory markers

193 Among the patients with leukocytosis, there was no observed relation between the

194 Animals that died had profound leukocytosis, thrombocytopenia, and elevated serum creat

195 sive reduction in inflammation (reduction in leukocytosis, thrombocytosis, and circulating interleuki

196 n and hematocrit, increased red blood cells, leukocytosis, thrombocytosis, splenomegaly, reduced seru

197 pidemiologic and clinical studies have shown leukocytosis to be an independent predictor of future ca

198 tachypnea (OR 1.9, P = 0.001), leukopenia or leukocytosis (total white blood cell count of <4500 or >

199 n baseline leukocyte count for patients with leukocytosis was 3,900 cells/microL (range, 1,200 to 72,

200 Peripheral blood leukocytosis was also enhanced in the type-1 but not the

201 Peritoneal leukocytosis was decreased in infected A1-a-deficient mi

202 Leukocytosis was detected with circulating "atypical" ly

203 Leukocytosis was documented in 70% (33/47) of the patien

204 nt mobilization of stem/progenitor cells and leukocytosis was elicited in selectin-deficient mice (L(

205 ore common (P< .01 for both comparisons) and leukocytosis was less common (P< .01) in patients with P

206 Leukocytosis was observed in 15 patients (58%).

207 a trend of shorter survival in patients with leukocytosis was observed.

208 Simultaneously, a prominent leukocytosis was seen; 1 day before being moribund, maca

209 were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertu

210 n of priming with markers of illness such as leukocytosis, weight loss, bacterial proliferation, and

211 Previous TIA and leukocytosis were also independently associated with cli

212 agnosis (specifically immunodeficiency), and leukocytosis were independently associated with reinfarc

213 Patients who developed leukocytosis were significantly more likely to develop t

214 ents with relatively low Alvarado scores and leukocytosis, when physical examination is confusing.

215 evated cytokine expression, and neutrophilic leukocytosis, which augments antilisterial defense.

216 ase for RANKL and TRAP; reduction of OPG and leukocytosis, which were significantly prevented by MRE,

217 Laboratory evaluation revealed leukocytosis (white blood cell count, 15.4 x 10(9)/L; no

218 TEL/PDGFbetaR transplanted mice developed leukocytosis with Gr-1(+) granulocytes, splenomegaly, ev

219 There is leukocytosis with lymphocytosis and apneic episodes.

220 Leukocytosis with lymphocytosis and pneumonia are common

221 sed on culture/polymerase chain reaction and leukocytosis with lymphocytosis.

222 features of human chronic myeloid leukemia: leukocytosis with maturing neutrophils, splenomegaly, he

223 All patients showed prompt leukocytosis with maximum blood neutrophils and lymphocy

224 y findings were elevated C-reactive protein, leukocytosis with neutrophilia, and anemia.

225 iferative disorder manifested by significant leukocytosis with neutrophilia, myeloid hyperproliferati

226 myeloproliferative syndrome characterized by leukocytosis with normal maturation of myeloid lineage c

227 in ligand formation, there was no finding of leukocytosis with these single ST3Gal deficiencies.

228 athy, graft dysfunction, and either fever or leukocytosis within three weeks after transplantation.

229 Leukocytosis without a recognizable etiology often poses

230 ed for adult patients with isolated fever or leukocytosis without considering the pretest probability

231 le phenotypes, including hair loss, dry eye, leukocytosis, xanthomatosis, and a reduced life span.