ライフサイエンスコーパス: leukosis

1 e and the causative agent of enzootic bovine leukosis.

2 us work characterizing ALV-J-induced myeloid leukosis.

3 is virus, and the chickens developed myeloid leukosis and hemangiomas within 2 months after hatching.

4 The transmembrane subunit (TM) of the avian leukosis and sarcoma virus (ALSV) envelope glycoprotein

5 tely defective in mediating subgroup A avian leukosis and sarcoma virus (ALSV-A) entry.

6 s the cellular receptor for subgroup A avian leukosis and sarcoma virus (ALSV-A).

7 The avian leukosis and sarcoma virus long terminal repeat (LTR) en

8 nown function with possible roles in myeloid leukosis associated with ALV-J.

9 eron and IL-10 and the progression of bovine leukosis in animals that develop more advanced disease s

10 ages may influence the progression of bovine leukosis in animals that develop persistent lymphocytosi

11 bgroups, ALV-J predominantly induces myeloid leukosis in meat-type chickens.

12 Pathogenicity and myeloid leukosis induction map to the env gene of ALV-J.

13 in chicken B-cell lymphomas induced by avian leukosis proviral integrations.

14 ne cis-acting determinants involved in avian leukosis sarcoma virus packaging RNA binding to Gag prot

15 ice that express TVA, the receptor for avian leukosis sarcoma virus subgroup A (ALSV-A), under the co

16 We are using avian leukosis-sarcoma virus (ALSV) vectors to generate mouse

17 The avian leukosis-sarcoma virus (ALV) group of retroviruses provi

18 t the amino acid level) to that of the avian leukosis-sarcoma virus family, it retains several sequen

19 portant for the efficient packaging of avian leukosis-sarcoma virus RNA.

20 In avian leukosis-sarcoma virus, however, we have shown that the

21 ed with infection by subgroups B and D avian leukosis-sarcoma viruses (ALVs).

22 substrates that are derivatives of the avian leukosis/sarcoma virus nucleocapsid-protease cleavage si

23 D cells were engineered to express the avian leukosis subtype A receptor, tv-a, to permit infection b

24 We have analyzed pol- mutants of avian leukosis virus (ALV) and murine leukemia virus (MuLV) fo

25 ind CCAAT/enhancer elements within the avian leukosis virus (ALV) and Rous sarcoma virus (RSV) LTR en

26 The avian leukosis virus (ALV) entry mechanism is controversial, w

27 d chicken embryos with the recombinant avian leukosis virus (ALV) EU-8 induces a high incidence of ra

28 Avian leukosis virus (ALV) has been used as a model system to

29 Avian leukosis virus (ALV) has endogenized prior to chicken do

30 ovide new evidence for the presence of avian leukosis virus (ALV) in both CEF supernatants and vaccin

31 Avian leukosis virus (ALV) induces bursal lymphoma in chickens

32 Avian leukosis virus (ALV) induces bursal lymphoma in tumor-su

33 Avian leukosis virus (ALV) induces tumors by integrating its p

34 cken strains are highly susceptible to avian leukosis virus (ALV) induction of bursal lymphoma, invol

35 Avian leukosis virus (ALV) infection induces bursal lymphomas

36 e factors that mediate alpharetroviral avian leukosis virus (ALV) integration are unknown.

37 Avian leukosis virus (ALV) is detrimental to poultry health an

38 The avian leukosis virus (ALV) long terminal repeat (LTR) contains

39 h different regions of the RSV and the avian leukosis virus (ALV) LTRs.

40 In this study, we identified avian leukosis virus (ALV) proviral integration sites in rapid

41 omosome-transgenic mice expressing the avian leukosis virus (ALV) receptor TVB, fused to monomeric re

42 ated that bridge proteins comprised of avian leukosis virus (ALV) receptors fused to epidermal growth

43 A new subgroup of avian leukosis virus (ALV) that includes a unique env gene, de

44 An avian leukosis virus (ALV) was found in some chicken embryos a

45 A new subgroup of avian leukosis virus (ALV), designated subgroup J, was identif

46 cteristics of a eukaryotic retrovirus, avian leukosis virus (ALV), offers a robust, eukaryotic versio

47 Avian leukosis virus (ALV), previously shown to be noninfectio

48 ficient retroviral vector based on the avian leukosis virus (ALV), we inserted into the chicken genom

49 An avian leukosis virus (ALV)-based retroviral vector system was

50 erence experiments have indicated that avian leukosis virus (ALV)-E may utilize a cellular receptor r

51 common retroviral integration site in avian leukosis virus (ALV)-induced B-cell lymphomas originally

52 n virus (EAV) family or to the avian sarcoma-leukosis virus (ALV)-related subgroup E endogenous virus

53 or the cytopathic subgroups B and D of avian leukosis virus (ALV-B and ALV-D), as a tumor necrosis fa

54 an retrovirus (EAV) and the endogenous avian leukosis virus (ALV-E), which originate from the chicken

55 Subgroup J avian leukosis virus (ALV-J) is a recently identified avian on

56 a cellular receptor of the subgroup J avian leukosis virus (ALV-J).

57 equence of 5'-ACGACAACA-3' for avian sarcoma-leukosis virus (ASLV) and 5'-AACA(A/C)AGCA-3' for human

58 ent of sites of integration of avian sarcoma-leukosis virus (ASLV) and human immunodeficiency virus (

59 the viral entry process of avian sarcoma and leukosis virus (ASLV) and human immunodeficiency virus t

60 model for the avian retrovirus avian sarcoma/leukosis virus (ASLV) and the filovirus ebolavirus Zaire

61 protein (Env) of the oncovirus avian sarcoma/leukosis virus (ASLV) contains an internal fusion peptid

62 The retrovirus avian sarcoma and leukosis virus (ASLV) enters cells via pH-independent me

63 een single virions bearing avian sarcoma and leukosis virus (ASLV) envelope glycoprotein (Env) and th

64 The fusion peptide of the avian sarcoma/leukosis virus (ASLV) envelope protein (Env) is internal

65 The entry process of the avian sarcoma and leukosis virus (ASLV) family of retroviruses requires fi

66 a previous study, we found avian sarcoma and leukosis virus (ASLV) gag genes in 19 species of birds i

67 ian retroviruses, we found avian sarcoma and leukosis virus (ASLV) gag genes in 26 species of gallifo

68 The avian sarcoma/leukosis virus (ASLV) is activated for fusion by a two-s

69 een with some subgroups of avian sarcoma and leukosis virus (ASLV) is associated with viral Env activ

70 vian or mammalian cells by avian sarcoma and leukosis virus (ASLV) or EnvA-pseudotyped murine leukemi

71 or entry of the retrovirus avian sarcoma and leukosis virus (ASLV) predicts that upon binding cell su

72 defect associated with an avian sarcoma and leukosis virus (ASLV) receptor resistance allele, tvb(r)

73 the other hand, integration of avian sarcoma-leukosis virus (ASLV) shows little preference either for

74 Binding of avian sarcoma and leukosis virus (ASLV) to its cognate receptor on the cel

75 and LTR expression from an avian sarcoma and leukosis virus (ASLV) vector.

76 Some retroviruses, such as avian sarcoma/leukosis virus (ASLV), employ a two-step mechanism in wh

77 has been proposed for the avian sarcoma and leukosis virus (ASLV), whereby interaction with specific

78 id-dependent fusion of the avian sarcoma and leukosis virus (ASLV), with endosomes.

79 o extend the host range of the avian sarcoma/leukosis virus (ASLV)-based RCASBP vectors produced two

80 iral infection mediated by the avian sarcoma-leukosis virus (ASLV-A) envelope glycoproteins can be ne

81 ar receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A), in viral entry.

82 he receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A), induces conformational changes

83 VA receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A), the five cell lines were resist

84 coprotein of the subtype A avian sarcoma and leukosis virus (ASLV-A).

85 ar receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A).

86 ar receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A).

87 he interactions between the subgroup A avian leukosis virus [ALV(A)] envelope glycoproteins and solub

88 ed the interactions between subgroup A avian leukosis virus [ALV(A)] envelope glycoproteins and Tva,

89 this hypothesis, the requirements for avian leukosis virus A (ALV-A) infection were examined.

90 e encoding the receptor for subgroup A avian leukosis virus and controlled by the astrocyte-specific

91 The budding of avian sarcoma leukosis virus and HIV-1 Gag virus-like particles contai

92 fecting both clones and subclones with avian leukosis virus and using a PCR-based assay to determine

93 viral replication by using avian sarcoma and leukosis virus as a model retrovirus.

94 action was found for HIV-1 and avian sarcoma/leukosis virus but not murine leukemia virus, suggesting

95 The avian leukosis virus DeltaLR-9 causes a high frequency of B-ce

96 The avian sarcoma and leukosis virus envelope glycoproteins, trimers composed

97 cell lymphomas induced by the nonacute avian leukosis virus EU-8.

98 ain of the TVB receptor for subgroup B avian leukosis virus fused to epidermal growth factor (EGF).

99 rovirus, subgroup A of the Avian Sarcoma and Leukosis Virus genus (ASLV-A), was studied by examining

100 ments (dr1) of avian sarcoma virus (ASV) and leukosis virus have the properties of constitutive trans

101 Avian leukosis virus induces lymphoma in chickens after provir

102 -1, murine leukemia virus, and avian sarcoma/leukosis virus integrations.

103 The fusion protein of avian sarcoma and leukosis virus is likely to fold into a six-helix bundle

104 etroviral [i.e., replication-competent avian leukosis virus long terminal repeat with splice acceptor

105 g the retroviral replication-competent avian leukosis virus long terminal repeat, splice acceptor (RC

106 g the A1 CCAAT/enhancer motif from the avian leukosis virus long terminal repeat.

107 us RCAS (replication-competent avian sarcoma-leukosis virus LTR splice acceptor)-mediated somatic gen

108 ed selection from a subgroup B avian sarcoma-leukosis virus of an extended-host-range variant (LT/SI)

109 in does not associate with the avian sarcoma leukosis virus or the HIV-1 budding complexes when ISG15

110 -a, to permit infection by recombinant avian leukosis virus produced by the replication-competent avi

111 We have adapted the avian leukosis virus RCAS (replication-competent avian sarcoma

112 e-lineage expression of the subgroup A avian leukosis virus receptor, TVA.

113 urthermore, later steps of avian sarcoma and leukosis virus reverse transcription were stimulated by

114 (tva), which encodes the receptor for avian leukosis virus subgroup A (ALV/A), we provide direct evi

115 Avian sarcoma and leukosis virus subgroup A (ASLV-A) entry is mediated by

116 ptad repeat domains of the avian sarcoma and leukosis virus subgroup A (ASLV-A) TM subunit of the env

117 envelope protein (Env) of avian sarcoma and leukosis virus subgroup A folds into a bundle during low

118 and its specific receptor for avian sarcoma leukosis virus subgroup A or B) system allow cell type-s

119 Cell killing by avian leukosis virus subgroup B (ALV-B) in cultures has been e

120 Avian leukosis virus subgroup J (ALV-J) is a simple retrovirus

121 egion, termed the E element or XSR, of avian leukosis virus subgroup J (ALV-J), a member of avian ret

122 ferrin, a serine/threonine kinase, and avian leukosis virus subgroup J glycoprotein.

123 ences in receptor usage among the many avian leukosis virus subgroups.

124 nvelope glycoprotein (EnvA) of avian sarcoma/leukosis virus subtype A (ASLV-A) binds to liposomes at

125 internal fusion peptide of the avian sarcoma/leukosis virus subtype A (ASLV-A) Env (EnvA) are importa

126 The receptor for avian sarcoma/leukosis virus subtype A (ASLV-A), Tva, is the simplest

127 murine leukemia virus (A-MLV), avian sarcoma/leukosis virus type A (ASLV-A), and influenza A virus.

128 lineages by infection with subgroup A avian leukosis virus vectors in lines of transgenic mice that

129 ransfer of genes carried by subgroup A avian leukosis virus vectors.

130 roviral vector derived from an avian sarcoma/leukosis virus which has been modified so that it uses t

131 Moloney murine leukemia virus, avian sarcoma leukosis virus, and foamy virus.

132 us, murine leukemia virus, and avian sarcoma-leukosis virus, and found that a statistical palindromic

133 human immunodeficiency virus, avian sarcoma leukosis virus, and influenza virus was independent of t

134 erminal domain of the alpharetrovirus, avian leukosis virus, revealing a previously undetected evolut

135 two new replication-competent avian sarcoma/leukosis virus-based retroviral vectors with amphotropic

136 ing mice susceptible to infection with avian leukosis virus-derived gene vectors.

137 common retroviral integration site in avian leukosis virus-induced lymphomas and has been implicated

138 novel envelope gene of the subgroup J avian leukosis virus.

139 on site in B cell lymphomas induced by avian leukosis virus.

140 lar receptors for subgroup B, D, and E avian leukosis viruses (ALV) encoded by the s1 allele of the c

141 susceptibility to subgroup B, D, and E avian leukosis viruses (ALV) is determined by specific alleles

142 , the cellular receptor for subgroup A avian leukosis viruses (ALV-A) can mediate viral entry when ex

143 ain of the TVA receptor for subgroup A avian leukosis viruses (ALV-A), fused to the MR1 single-chain

144 Subgroups B, D, and E avian leukosis viruses (ALV-B, -D, and -E) share the same chic

145 ning RNA of both subgroup E endogenous avian leukosis viruses (ALV-E) and endogenous avian viruses (E

146 d genomic RNAs of wild-type and mutant avian leukosis viruses (ALVs) in an attempt to (i) better unde

147 D and noncytopathic subgroup E of the avian leukosis viruses (ALVs).

148 Avian sarcoma and leukosis viruses (ASLV) are unusual among retroviruses i

149 Receptor specificity in avian sarcoma and leukosis viruses (ASLV) maps to the central region of th

150 sceptibility to subgroup A avian sarcoma and leukosis viruses (ASLV-A) was recently identified by a g

151 r for subgroup B, D, and E avian sarcoma and leukosis viruses (ASLVs) is a tumor necrosis factor rece

152 eceptor for the subgroup A avian sarcoma and leukosis viruses [ASLV(A)] is the cellular glycoprotein

153 he receptor for subgroup C avian sarcoma and leukosis viruses [ASLV(C)], i.e., Tvc, a protein most cl

154 r region of the subgroup A avian sarcoma and leukosis viruses envelope glycoproteins, SUATM129 produc