ライフサイエンスコーパス: leukotriene A

コーパス検索結果 (１語後でソート)

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1 We also show that the LTB(4) precursors leukotriene A(4) (LTA(4)) and 5-hydroperoxyeicosatetreno

2 meras generated from 5-lipoxygenase(-/-) and leukotriene A(4) (LTA(4)) hydrolase(-/-) mice, we demons

3 nes is the conversion of arachidonic acid to leukotriene A(4) (LTA(4)) in two successive reactions ca

4 ntitate the major product in the reaction of leukotriene A(4) (LTA(4)) with deoxyguanosine (dGuo).

5 iene biosynthesis, the addition of exogenous leukotriene A(4) (LTA(4); the precursor of LTB(4)) to re

6 such as the prostaglandin endoperoxides and leukotriene A(4) epoxide of mammalian biology and the al

7 We studied leukotriene A(4) hydrolase (LTA(4)H) as a relevant targe

8 Leukotriene A(4) hydrolase (LTA(4)H) is a proinflammator

9 The leukotriene A(4) hydrolase (LTA(4)H) protein is regarded

10 Modulation of the leukotriene A(4) hydrolase (LTA4H) locus, which controls

11 peripheral blood neutrophils contained both leukotriene A(4) hydrolase and 5-lipoxygenase exclusivel

12 results demonstrate for the first time that leukotriene A(4) hydrolase can be accumulated in the nuc

13 In this study, we asked if leukotriene A(4) hydrolase co-localizes with 5-lipoxygen

14 The finding of abundant leukotriene A(4) hydrolase in the soluble nuclear fracti

15 ipoxygenase, the subcellular distribution of leukotriene A(4) hydrolase is cell-specific and dynamic,

16 uited into inflamed appendix tissue, whereas leukotriene A(4) hydrolase remained cytosolic.

17 s rapidly imported into the nucleus, whereas leukotriene A(4) hydrolase remained cytosolic.

18 Leukotriene A(4) hydrolase was also found to accumulate

19 emistry and immunofluorescence revealed that leukotriene A(4) hydrolase, like 5-lipoxygenase, was mos

20 ible mutant maps to the lta4h locus encoding leukotriene A(4) hydrolase, which catalyzes the final st

21 generated by the enzymes 5-lipoxygenase and leukotriene A(4) hydrolase.

22 al action of two enzymes: 5-lipoxygenase and leukotriene A(4) hydrolase.

23 step transformation of arachidonic acid into leukotriene A(4), leading to the synthesis of various le

24 shows similarity to the N-terminal domain of leukotriene A-4 hydrolase.

25 ls and augmented transcellular conversion of leukotrienes, a disturbance in platelet-leukocyte intera

26 ominent among such signals are the cysteinyl leukotrienes, a family of potent proinflammatory lipid m

27 on of an arachidonic acid hydroperoxide to a leukotriene A (LTA) type epoxide by specific lipoxygenas

28 ,13trans,15cis-C18.omega3, an epoxide of the leukotriene A type.

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