ライフサイエンスコーパス: level

1 story of prostate cancer with increasing PSA level.

2 s, with concordant findings at the proteomic level.

3 derstanding of the technology at a molecular level.

4 conscious volition down to the single-neuron level.

5 e distinct and resolvable at the subcellular level.

6 are found on the topological and conceptual level.

7 meningeal enhancement at the affected spine level.

8 isingly difficult to obtain at the molecular level.

9 GHT output, indicating modulation at the SCN level.

10 e development of E/I balance at the cellular level.

11 cells orchestrate transcription on a systems level.

12 their discrete voltage regulated operational levels.

13 ptional, post-transcriptional and epigenetic levels.

14 n HCEC, but had no effect on CYP27B1 protein levels.

15 protective, as it reduces lipid peroxidation levels.

16 e extracellular indole to restore tryptophan levels.

17 of the DNA conductance between two discrete levels.

18 alidated 4-point scale, and comparison of E2 levels.

19 the largest potential sources of rising sea levels.

20 e midbrain and hypothalamus exhibit low FMRP levels.

21 No probe was identified for AST levels.

22 gulating cellular NEIL1 steady state protein levels.

23 elated directly with circulating cholesterol levels.

24 Z in the gene body correlate with transcript levels.

25 fluencing angiogenesis within Se nutritional levels.

26 d depletion of topo-II did not change CENP-A levels.

27 who were not, according to circulating mtDNA levels.

28 mentation, cell volume and nuclear cyclin D1 levels.

29 tion was still regulated by extracellular Pi levels.

30 dent reductions in PCSK9 and LDL cholesterol levels.

31 s is associated with their iridoid glycoside levels.

32 duction, thereby elevating plasma fibrinogen levels.

33 expression greater than double the baseline levels.

34 which is associated by increased IL-31 serum levels.

35 l tissues confirmed tissue-specific RD3 mRNA levels.

36 r a stronger association at higher turbidity levels.

37 ion and reduced circulating 17beta-estradiol levels.

38 here is a striking increase in seed dormancy levels.

39 ch reader at the lesion, region, and subject levels.

40 s are strongly influenced by Hrd1 expression levels.

41 o mediate significant decreases in aggregate levels.

42 imiting toxicity analysis set: three at dose level 1 (1 mg/kg), three at dose level 2 (3 mg/kg), six

43 estion or idiopathic liver failure (DT) in a level 1 trauma center and large transplant center.

44 ree at dose level 1 (1 mg/kg), three at dose level 2 (3 mg/kg), six at dose level 3 (10 mg/kg), and s

45 GeneXpert system was available in 14%-41% of level 2 facilities in the 3 countries for which there we

46 atment of Diabetic Retinopathy Study (ETDRS) level 20-35 than in patients with ETDRS level <20 (P = 0

47 three at dose level 2 (3 mg/kg), six at dose level 3 (10 mg/kg), and six at dose level 4 (20 mg/kg).

48 at dose level 3 (10 mg/kg), and six at dose level 4 (20 mg/kg).

49 ed with L. braziliensis and reduced IL-1beta levels after cure.

50 s with significantly higher serum vitamin D3 levels after treatment (P = 0.007) demonstrated increase

51 iving and nonviable systems at the molecular level and has a high potential on early diagnosis.

52 ear how this is orchestrated at the cellular level and how cell fate is affected by severe tissue dam

53 o gather information about the external food level and to ingest food when the conditions are good.

54 Along with educational level and use of internet support groups, uncertain resu

55 found that GnT-III expression regulates the levels and activation of the heavily glycosylated Notch

56 show that Pth4 can alter calcium/phosphorus levels and affect expression of genes involved in phosph

57 Reduced oxygen levels and ATP consumption rates were simulated to chara

58 BAX expression levels and cytosolic conformation regulate sensitivity t

59 molecular link between intracellular Ca(2+) levels and energy homeostasis.

60 nto the relationship between gene transcript levels and HLA ligand presentation.

61 detect interactions between hormonal plasma levels and ocular parameters.

62 vealed a direct correlation between serum E2 levels and pLTF expression in cycling female rats.

63 tantial cell-to-cell variation in expression levels and propagation of this variation between molecul

64 was based on polymorphism-driven expression levels and specificities, we predicted and tested inhibi

65 use of an active site inhibitor reduces Skp2 levels and stabilizes LT, leading to enhanced MCV replic

66 ticulocytes functionally or at the molecular level, and importantly no aberrant protein expression.

67 hildren who outgrew CMA showed miRNA-193a-5p level, and its related targets expression, similar to th

68 saturation, respiratory rate, consciousness level, and other evidence of clinical deterioration.

69 delays in mice varied depending on activity levels, and axonal myelination and conduction velocity e

70 thods of and times of MRD assessment, cutoff levels, and disease subtypes.

71 lysis.SIGNIFICANCE STATEMENT Neuronal energy levels are critical for proper CNS function, but the rel

72 Indeed, high Blimp1 expression levels are detected in invasive p130Cas/ErbB2 cells and

73 The projected increases in sea levels are expected to affect coastal ecosystems.

74 varying FC networks constructed at different levels are fused for eMCI classification.

75 thesizing that higher postchallenge glucagon levels are observed in subjects with impaired glucose to

76 INTERPRETATION: CSF phosphorylated-tau levels are positively associated with cerebral tau burde

77 uilibrative nucleoside transporter 1 (eENT1) levels are reduced in humans at high altitude and in mic

78 Meanwhile, both RanBP9 and tau levels are simultaneously reduced by Hsp90 or Hsc70 inhi

79 tected in serum within 1 day, and serum VEGF levels are suppressed for at least 8 to 12 weeks.

80 Here we show that hydrolase levels between human ALF from healthy and CF patients di

81 PET discovery process, involving expression level (Bmax) and biodistribution determination, a PET-sp

82 ntify changes in projected ranges and threat level by the years 2061-2080, for 12 European forest tre

83 cific findings were confirmed at the protein level by Western blot.

84 he deficits, whereas down-regulation of P311 levels by lentiviral RNA interference reproduced the def

85 abidopsis thaliana), OR increases carotenoid levels by posttranscriptionally regulating phytoene synt

86 s rates are determined, at the translational level, by properties of the transcript's sequence.

87 probing depth (PD), and clinical attachment level (CAL).

88 ture sickness absence and disability pension levels can be used by patients when planning their work,

89 maternal age, country of origin, educational level, cohabitation with a partner, height, early pregna

90 l pro-B-type natriuretic peptide (NT-proBNP) levels compared with usual care alone.

91 Finally, endogenous MSK1 levels concomitantly increased to regulate MOR gene expr

92 In mice, subcutaneous AT Tshb expression levels correlated directly with circulating cholesterol

93 closely with levels of S100A4, whereas MMP9 levels correlated more closely with the S100 family memb

94 lled for patient-, surgeon-, and institution-level covariates.

95 Only 8% monitored their blood glucose levels daily, 15% monitored weekly, and 10% reported che

96 nsitive epilepsy, alpha-related blood oxygen level-dependent signal changes demonstrated lower decrea

97 identification relatively easy, but species-level diversity of Pseudotrichonympha is understudied.

98 s can elevate dissolved organic matter (DOM) levels due to ash input and algal growth in source water

99 und that B. microti reaches high parasitemia levels during the first week of infection in all three m

100 Among the patients (n = 19) whose HBsAg levels ever dropped below 10 IU/mL, only one and three p

101 resistance resulting in the lower detectable level for AFB1 quantification.

102 CCR4-Not deadenylase complex, restored mRNA levels for a class of downregulated, H3K36me3-rich genes

103 ere carried out at 5, 50 and 500microgkg(-1) levels for rapeseed, sunflower seeds and soybean.

104 respiratory epithelium, with very low silver levels found in blood and no detectable silver measured

105 tural waters with millimolar sodium chloride level (freshwater, drinking water, and aquarium water, a

106 n several species, and also at the aggregate level (G); however, there is ambiguous evidence for the

107 e-specific super-enhancer, resulting in high-level gene activation.

108 ic adenocarcinoma cells generated micromolar level H2O2 during just 1 min of direct CAP treatment on

109 genome-wide investigation of DNA methylation levels has been limited to reference transposable elemen

110 paediatric donor-recipient pairs with allele-level HLA matching who received a single unit umbilical

111 has a conspicuous body plan that makes genus-level identification relatively easy, but species-level

112 ut, crucially, some differences in biomarker levels (IL-1beta and sRANKL) and bacterial species betwe

113 Bycatch mortality has high population-level impacts in all three species, with shearwaters hav

114 Reduced p62 levels impair interaction of p62 with Keap1, which furth

115 ion values lower than the maximum admissible level in this matrix ([Hg]=1mg/kgwet weight,ww).

116 Decreased Sesn2 levels in aging lead to a blunted ischemic AMPK activati

117 ion of thermogenesis linked to increased HDL levels in APOE*3-Leiden.CETP mice.

118 mportantly, selinexor decreased AXL and GAS6 levels in CAL62 and HTH83 cells and suppressed the phosp

119 investigate associations of n-3 and n-6 PUFA levels in colostrum and breast milk with allergic diseas

120 ially recruited to fine-tune gene expression levels in each cardiac chamber.

121 Both TmELO genes were expressed at various levels in eggs, 1(st) and 2(nd) instar larvae, mature la

122 1,25(OH)2D3 increased CYP27B1 mRNA levels in HCEC, but had no effect on CYP27B1 protein lev

123 at transcriptional and post transcriptional levels in OA chondrocytes.

124 examined differences in individual cytokine levels in patients with chronic liver disease, but compr

125 Finally, we confirmed low 25D plasma levels in patients with IBD with active inflammation.

126 We aimed to investigate urinary NP and BPA levels in relation to biomarkers of oxidative/nitrative

127 us to DRN-driven serotonergic control of CRF levels in the amygdala may contribute to the transition

128 he duodenal crypt-villus axis and buffers Cu levels in the cytosol of enterocytes.

129 shown to have an additive effect on FEV1/FVC levels in the genetic risk score analysis; were associat

130 from MRN-driven serotonergic control of CRF levels in the hypothalamus to DRN-driven serotonergic co

131 ne greatly increase HS content and sulfation levels in the lateral hypothalamus and that HS contribut

132 ed a classifier based on the gene expression levels in the non-infected cells, and demonstrated reaso

133 creased to 6045 ng h/ml (P=0.03), and trough levels increased to 218 ng/ml (P=0.03), above the 90th p

134 Organization-level Independent Practice and Support subscale, an NP-P

135 We created zip code level indicators of happiness, food, and physical activi

136 RI when subjects shift thoughts between high-level internally directed cognitive states, when thinkin

137 as led to the development of several service-level interventions intended to improve care quality.

138 1, and 33, were separated at semipreparative level into their pure enantiomers.

139 ncrease in NMS with lower baseline Abeta1-42 level is an important finding that will have to be repli

140 COS, DHT exposure led to reduced adiponectin levels, larger adipocyte size, and reduced insulin sensi

141 such that patterned disorder at the cellular level leads to the emergence of organism-level order.

142 in UK beef cattle, but it is unclear at what levels liver fluke burdens cause production losses.

143 DRS) level 20-35 than in patients with ETDRS level <20 (P = 0.005).

144 and Fermi arcs live entirely above the Fermi level, making them inaccessible to conventional angle-re

145 ate how heterogeneity at the transcriptional level manifests in the physiologic profile of individual

146 Measurement of lactate levels may have utility in early risk stratification of

147 ption, smoking, and urinary sodium excretion levels measured at recruitment.

148 Here we developed a population-level microsatellite profiling approach, SID (Saccharomy

149 uman fetuses in utero and found that systems-level neural functional connectivity was diminished in f

150 We furthermore show how the level of added noise can be continuously adapted even to

151 The SF bread, characterized by highest level of alcohols, received the highest score for aroma

152 t contractile function to compensate for the level of available energy.

153 ntravascular bacterial cell numbers (ie, the level of bacteremia), in patients at the time of clinica

154 mble-encoded CS-US association predicted the level of behavioural conditioning in each mouse.

155 s associated with college completion vary by level of childhood disadvantage for depression and metab

156 Given the current level of childhood obesity, the models predicted that a

157 edelic phenomenology constitutes an elevated level of consciousness - as measured by neural signal di

158 esponses to TAF mutations correlate with the level of downstream, rather than overall, Taf1 cross-lin

159 ression phenotypes were also affected at the level of epithelial-to-mesenchymal transition and the ER

160 mmendations from moderate, low, and very low level of evidence on the topics of: communication with f

161 ESCd display a high level of expression of genes implicated in migration and

162 age to have a lower CpG content and a higher level of expression.

163 oefficient of gene differentiation (Gst) and level of gene flow (Nm) revealed by ISSR were 0.4498, 0.

164 However, their arguments are based on a level of generality that fails to appreciate the specifi

165 The level of IFNAR1*557Gluext*46 mutant protein expressed in

166 zation methods to improve separation and the level of information obtained from a single analytical s

167 ffect of vasopressin is not dependent on the level of maturation (depolarizing vs. hyperpolarizing) o

168 The level of nitrogen (N), phosphorus (P), zinc (Zn), iron (

169 r functionalities that provide a therapeutic level of NO necessary to promote angiogenesis and to pro

170 er, the optimal solutions depend on both the level of noise and how it impacts a particular computati

171 e transcriptomic and genomic analysis at the level of one single plant cell type, the root hair cell,

172 An appropriate level of process description is crucial to constructing

173 Increased level of proinflammatory cytokine interleukin (IL)-12 co

174 otection against the same natural enemy, the level of protection corresponded to the higher of the tw

175 city and translucency of surfaces arise at a level of representation where 3D shape is made explicit.

176 In this study, the level of sanitation access of surrounding households was

177 piriform cortex, with robust effects at the level of single trials.

178 ingly, C. cohnii was characterised by a high level of sulfur compounds (dimethyl sulfide, ethanethiol

179 to high and low concentrations of CO2 at the level of transcripts, proteins and enzyme activity.

180 protocols which allow to achieve increasing levels of accuracy, it is relatively simple to implement

181 nd showed that these cells expressed reduced levels of B-lineage transcription factors and B cell rec

182 Env-mediated membrane fusion and had higher levels of binding affinity with NHR peptide N46.

183 genetic models in fact well predict observed levels of both intra- and interhost variability.

184 ecruited at the diseased tissue produce high levels of CCL-2 and IL-8 and contribute to the inflammat

185 ified miR-449b could regulate the expression levels of CDK6, c-MYC, HDAC1 and BCL-2.

186 thout microglial activation, and reduced the levels of cerebellar ATXN2.

187 nhibited pharmacologically, the steady-state levels of circular RNAs increased while expression of th

188 dystrophy, exhibit a substantial decrease in levels of circulating exosomal miRNAs.

189 Increased CPB duration yielded in higher levels of circulating mitochondrial (mt)DNA, soluble thr

190 creased forcing of the climate by increasing levels of CO2 and CH4.

191 these assemblies is a result of significant levels of cooperative binding that is present in both so

192 EMD provides highest levels of CRC; however, the addition of CM increases gin

193 One-third of CSU patients had elevated levels of CRP.

194 tions at room temperature proceeds with high levels of diastereocontrol, leading to beta-amino ketone

195 y, and this efficiency was consistent across levels of difficulty of the same task.

196 r of circulating HIV strains exhibiting high levels of diversity and recombination.

197 nd redundancy to generate cell type-specific levels of dve expression and stable photoreceptor fate.

198 s, which account for the observed trends and levels of enantioselectivity, are presented.

199 e from IL5tg mice, including 800-fold higher levels of eotaxin-1.

200 One of four radiologists with different levels of expertise (1-9 years) first reviewed only a fr

201 in cell culture was inversely related to the levels of expression of GRP78 and that both proteins int

202 etabolism is brought about by changes in the levels of expression of relatively few genes, but this i

203 1 is essential for maintaining physiological levels of Fe/S cluster biogenesis proteins during iron d

204 enic indices, markers of inflammation, serum levels of fibroblast growth factor 21 (FGF21), and activ

205 signature measuring the relative expression levels of four host messenger RNAs, was developed to dis

206 en accompanied by dyslipidemia with elevated levels of free fatty acids (FFAs).

207 our objectives were to determine and compare levels of glutathione, as well as ergothioneine, in diff

208 e observed that in drought-responsive genes, levels of H2A.Z in the gene body correlate with transcri

209 arasite virulence and genetically determined levels of host-plant resistance and tolerance.

210 IL-10 were significantly decreased, and the levels of IL-2 in the serum of AOM rats increased after

211 mosterol in the HSV envelope support similar levels of infectivity.

212 ced insulin sensitivity, and low circulating levels of insulin and insulin-like growth factor 1 (IGF-

213 Levels of interleukin 23 (IL23) and T-helper (Th) 17 cel

214 Indeed, RIMA knockdown reduces the nuclear levels of IYO and prevents its prodifferentiation activi

215 Increased levels of leukocytes, platelets, and tissue factor-posit

216 We examined levels of liver fat, lipogenic indices, markers of infla

217 In individual tumors, levels of MMP2 and MMP13 correlated more closely with le

218 led to high expansion activity and elevated levels of MutSbeta complex, indicating that MutSbeta abu

219 Cellular and secreted levels of OEA and PEA (P < 0.001-0.001) were increased i

220 and USP10, which are involved in regulating levels of p53 and MDM2.

221 ieved that RASopathies are caused by altered levels of pathway activation, the signaling changes in d

222 To compare the circulating plasma levels of peptide YY and ghrelin in control subjects and

223 abolic stress in response to DSS with higher levels of phospho-AMPK and lower levels of phosphorylati

224 with higher levels of phospho-AMPK and lower levels of phosphorylation of mammalian target of rapamyc

225 ies with both high mean phenotype values and levels of plasticity that are appropriate for the target

226 ion between the prevalence of low VA and the levels of PP.

227 ation respectively, which we use to tune the levels of Raf/MEK/ERK signaling.

228 68%) of 44 individual patients had different levels of responses within the M1 and M2 clones.

229 inearly (p<0.05) by raising the substitution levels of rice with ASF.

230 MMP2 and MMP13 correlated more closely with levels of S100A4, whereas MMP9 levels correlated more cl

231 -34-Mphis possess significantly greater mRNA levels of select restriction factor genes than CSF-1-Mph

232 el to understand the significance of altered levels of SERCA, IP3R, and RyR on the intracellular calc

233 ium dynamics can be modified by changing the levels of SERCA, IP3R, and/or RyR.

234 infected Irgm1-deficient mice displayed high levels of serum cytokines typifying profound autoinflamm

235 Imatinib also reduced levels of serum tryptase, a marker of mast-cell activati

236 d in both mouse models it normalized protein levels of several SCA2-related proteins expressed in Pur

237 The expression levels of some markers for AML subtypes and c-MYC regula

238 Consistently, restoring high levels of SOX5/6/21 in human primary glioblastoma cells

239 ransplanted over 11 y ago showed the highest levels of Streptococcus (18.4%), Haemophilus (12.7%) and

240 inary team training scenario with 3 possible levels of surgical realism: (1) SimMan (Laerdal) (contro

241 The expression levels of tau and TDP-43 were inverse in the frontal cor

242 Circulating monocytes uniformly express high levels of the canonical E-selectin binding determinant s

243 dent neural input, originated from different levels of the central nervous system, to the different c

244 In addition, the levels of the immunomodulatory cytokines IL-1alpha and I

245 ls are prone to seizures and have high brain levels of the inflammatory cytokine IL-1beta.

246 es, we find that cancer cells depend on high levels of the iron-sulfur cluster biosynthetic enzyme NF

247 f DM and the glycosylated hemoglobin (HbA1c) levels of the patients in the DM group were recorded.

248 ugt80A2 mutants exhibit significantly lower levels of total SGs they are morphologically indistingui

249 sions in biopsy specimens or persistent high levels of tTGA.

250 duce defective CD11b associate with elevated levels of type I interferon (IFN-I) in lupus, suggesting

251 elt event in two watersheds with contrasting levels of urbanization.

252 Furthermore, levels of VEGF-D and MCP-1 in patient sera correlated po

253 sed in patient fibroblasts was comparable to levels of WT IFNAR1 in control fibroblasts.

254 sociation between obesity and disability has leveled off in more recent years, and is even improving

255 Decreased DICER1 levels or Alu-RNA accumulation triggers cytosolic escape

256 th increased prostate-specific antigen (PSA) level, or (c) had a prior history of prostate cancer wit

257 lar level leads to the emergence of organism-level order.

258 suburban vegetation and corresponding ground-level ozone and particulate matter.

259 increased serum Phleum pratense-specific IgE levels (P = .001) compared with those in the control arm

260 Individual-level patterns of missed general practice appointments m

261 ng nanotechnology that would allow molecular-level phenomena to drive such movements in artificial sy

262 e we use extreme value theory to combine sea-level projections with wave, tide, and storm surge model

263 In turn, increased ferritin protein levels promote the expression of the promitotic transcri

264 of crab spiked into complex food matrices at levels ranging from 0.1 to 10(5) parts per million (weig

265 Additionally, while total FoxM1 levels remained constant, there was a significant decrea

266 ptive fields (vRFs) to changes in population-level representations.

267 xpression and somatic copy number alteration levels (rho = -0.484, P = 2 x 10-10).

268 Global climate change drives sea-level rise, increasing the frequency of coastal flooding

269 The Sphagnome Project encompasses a genus-level sequencing effort that represents a new type of mo

270 Randomized trials evaluating treatment levels significantly above 90 mm Hg are needed.

271 erved in healthy carriers nor at the species-level, suggesting infection-associated, short-term, with

272 ions were similar (P = .73) across all genus-level taxonomic categories.

273 rgp120 vaccine had higher-magnitude antibody levels than adults (gp120 median FIs of 15,509 [infants]

274 vity by reducing the cellular dNTP pool to a level that cannot support productive reverse transcripti

275 Our study elucidates at atomic level that the hydrophobicity and substitution geometry

276 C and to understand how variation in protein levels that arise due to diabetes contribute to differen

277 was based on analyses at three fortification levels that showed satisfactory recoveries (62.06-129.93

278 ole in force generation, while on the tissue level the spatial organization of forces determines the

279 ce of oxygen consumption depends on activity levels, these findings are consistent with the hypothesi

280 However, difficulties in relating sound levels to abundance have impeded the use of passive acou

281 en the cohorts, and that changes in antibody levels to Apical Membrane Antigen 1 suggested a decrease

282 ty against bacterial strains possessing high level vancomycin resistance mediated by the reprogrammin

283 m published studies and incorporated patient-level variation.

284 POP levels varied significantly among sites, more than 36-fo

285 country, and SCD phenotype, a low hemoglobin level was significantly associated with TRV and microalb

286 At molecular level we provide evidence for non-canonical mode of acti

287 To study the biological effects of low GSH levels, we disrupted its synthesis both at birth by bree

288 CSF tau levels were compared between groups and correlated with

289 H2O2 levels were consistent across subsamples of the same liv

290 Moreover, PTX2 and FX levels were correspondingly reduced in SR-AI-deficient m

291 eral blood ADAM17 activity and soluble CD163 levels were elevated in stroke patients relative to non-

292 Thus, reductions in serum calprotectin levels were linked to therapeutic responses to antibioti

293 tro techniques at the molecular and cellular levels were now applied to assess their functional quali

294 ALS mutant SOD1 induced reductions in Miro1 levels were Parkin dependent.

295 lains between 60% and 96% (at +/-20%) of TEX levels while it is less clear for xylenes at some locati

296 of SR patients without MRD at any detectable level who had excellent 5-year EFS (98.1%) and OS (100%)

297 transcriptomes using RNA-seq and amino acid levels with N treatment in tea (Camellia sinensis), the

298 cyte Ca(2+) can adjust to a new steady-state level, with an impact on surrounding brain cells, remain

299 At least six miRNAs show cycling expression levels within the pigment dispersing factor (PDF) cell-p

300 This study used state-level Youth Risk Behavior Surveillance System (YRBSS) da