ライフサイエンスコーパス: level of

1 , 0.57-1.66) for participants with serum CRP levels of 1 to 3 mg/L and 1.12 (95% CI, 0.65-1.93) for p

2 Plasma levels of 17 cytokines were screened in the same set of

3 However, above a local noise level of 20%, the model with nonspecific plasticity outp

4 The serum levels of 25-hydroxy VD, TGF-beta1, TIMP-1, MMP2 and MMP

5 tment also robustly increases the myocardial levels of 3 metabolites, nicotinic acid adenine dinucleo

6 o a degree commensurate with adulteration at levels of 3-30%w/w.

7 schizophrenia at the suggestive significance level of 5 x 10(-5).

8 Fetal fibronectin levels of 50 ng/mL or greater at 16 to 22 weeks identifi

9 documented hypoglycemia with a blood glucose level of 55 mg per deciliter (3.1 mmol per liter) or bel

10 We determined the circulating levels of 7 selected candidate miRNAs in 14 LTxR with AR

11 or computational inference of the expression levels of 81% of non-measured transcripts.

12 we describe functional units, at a cellular level, of a compound eye from the base of the Cambrian,

13 ernal Ags while simultaneously inducing high levels of Abs toward hemagglutinin.

14 This level of accuracy for classification as well as severity

15 protocols which allow to achieve increasing levels of accuracy, it is relatively simple to implement

16 Such adhesive interactions enhanced levels of active Rac in adherent and fusing myoblasts, a

17 Therefore, the low level of adaptation in diverse streams cannot be explain

18 We furthermore show how the level of added noise can be continuously adapted even to

19 hieved about 90%, suggesting relatively high level of adherence.

20 Lower baseline levels of adiponectin significantly predicted ketamine's

21 Levels of airway inflammation, mucus, fibrosis, and airw

22 The SF bread, characterized by highest level of alcohols, received the highest score for aroma

23 Nrf2 decreased steady-state levels of alpha-synuclein in part by increasing alpha-sy

24 poly(A) additions to mt-tRNA led to reduced levels of aminoacylated pool of certain mt-tRNAs and mit

25 These swellings contain high levels of amyloid precursor protein processing enzymes (

26 iations in pitch or timbre at the univariate level of analysis were largely overlapping.

27 observed 3-fold increases in tumor mass and levels of angiogenesis markers in animals injected with

28 Levels of anti-inflammatory cytokine TGF-beta remained p

29 after ovalbumin challenge (P < .05), higher levels of apoptosis (Annexin V positivity, P < .005), an

30 guidelines (2004-2013) and had achieved high levels of ART uptake in HIV-diagnosed individuals from 2

31 Levels of autoantibodies and B2A-CIC were quantified imm

32 t contractile function to compensate for the level of available energy.

33 aparoscopic lysis of adhesions with a higher level of awareness and use strategies to mitigate this r

34 nd showed that these cells expressed reduced levels of B-lineage transcription factors and B cell rec

35 ntravascular bacterial cell numbers (ie, the level of bacteremia), in patients at the time of clinica

36 mble-encoded CS-US association predicted the level of behavioural conditioning in each mouse.

37 Env-mediated membrane fusion and had higher levels of binding affinity with NHR peptide N46.

38 genetic models in fact well predict observed levels of both intra- and interhost variability.

39 Furthermore, the expression level of c-Jun was significantly higher in TNBC tumors t

40 Genetically elevated circulating levels of C-reactive protein (CRP), interleukin-1 recept

41 ind critical slowing down in the data at the level of California and the United States in the years b

42 patients with melioidosis resulted in lower levels of calprotectin and C-reactive protein (P < 0.000

43 tem, where patients can choose to bypass any level of care, simulations suggest that a system of mana

44 tioned media-derived IFN-gamma exhibited low levels of Cathepsin K, TRAP, RANK, and tumor necrosis fa

45 ecruited at the diseased tissue produce high levels of CCL-2 and IL-8 and contribute to the inflammat

46 ified miR-449b could regulate the expression levels of CDK6, c-MYC, HDAC1 and BCL-2.

47 te pro-drug esters, suggesting that the high levels of cellular 2OG may preclude inhibition.

48 thout microglial activation, and reduced the levels of cerebellar ATXN2.

49 s associated with college completion vary by level of childhood disadvantage for depression and metab

50 Given the current level of childhood obesity, the models predicted that a

51 wer metabolic syndrome for whites across all levels of childhood disadvantage.

52 nhibited pharmacologically, the steady-state levels of circular RNAs increased while expression of th

53 Higher levels of circulating DJ-1 were associated with increase

54 dystrophy, exhibit a substantial decrease in levels of circulating exosomal miRNAs.

55 Increased CPB duration yielded in higher levels of circulating mitochondrial (mt)DNA, soluble thr

56 creased forcing of the climate by increasing levels of CO2 and CH4.

57 re highly evolutionarily plastic both at the level of coding sequence and expression across A. thalia

58 ve cognitive deterioration, others lower the level of cognition but exert relatively stable effects o

59 ound that decisions associated with a higher level of cognitive dissonance elicited a stronger negati

60 cognitive reasoning task involving different levels of complexity, followed by a second resting-state

61 edelic phenomenology constitutes an elevated level of consciousness - as measured by neural signal di

62 these assemblies is a result of significant levels of cooperative binding that is present in both so

63 and associated semantic processing to higher levels of cortex than reported here.

64 EMD provides highest levels of CRC; however, the addition of CM increases gin

65 One-third of CSU patients had elevated levels of CRP.

66 whether plasma or cerebrospinal fluid (CSF) levels of cytokines and chemokines predicted C-IRIS and

67 Levels of cytokines and chemokines were compared between

68 High levels of DAF-16 (in the daf-16 (mu86); muIs61 strain) n

69 Analyses incorporating both levels of data have the potential to provide epidemiolog

70 midine biosynthesis to enhance the intrinsic levels of deoxycytidine triphosphate (dCTP).

71 betes mellitus (T2DM) patients (n = 38), the levels of dG-gx-dC and dG-gx-dA in leukocyte DNA were 1.

72 Levels of DHA-derived epoxides are lower in colon tissue

73 Some GBS cases do not exhibit a high level of diagnostic certainty.

74 tions at room temperature proceeds with high levels of diastereocontrol, leading to beta-amino ketone

75 nce of visual inhibition or whether the GABA levels of different cortical regions selectively influen

76 Depending on their origin and level of differentiation at which they are harvested, st

77 y, and this efficiency was consistent across levels of difficulty of the same task.

78 r of circulating HIV strains exhibiting high levels of diversity and recombination.

79 esponses to TAF mutations correlate with the level of downstream, rather than overall, Taf1 cross-lin

80 ative omics analyses, and discover that mRNA levels of DTL, DCAF4, 12 and 13 are consistently elevate

81 nd redundancy to generate cell type-specific levels of dve expression and stable photoreceptor fate.

82 be classical pathway (CP) inhibition at the level of early component C1.

83 form of X-linked HED (XLHED), contained low levels of EDA capable of binding to EDAR.

84 mbines high levels of step economy with high levels of efficiency and scalability has remained elusiv

85 lation as single regioisomers with excellent levels of enantiomeric enrichment.

86 chlorides are difficult to prepare with high levels of enantiopurity and are prone to undergo deleter

87 s, which account for the observed trends and levels of enantioselectivity, are presented.

88 ency in the thioredoxin system that increase levels of endogenous hydrogen peroxide in the yeast Sacc

89 ntial proarrhythmic effects of HC at various levels of engraftment.

90 e from IL5tg mice, including 800-fold higher levels of eotaxin-1.

91 ression phenotypes were also affected at the level of epithelial-to-mesenchymal transition and the ER

92 Together, our findings demonstrate that the levels of ESX-1 substrates in M. marinum are fine-tuned

93 mmendations from moderate, low, and very low level of evidence on the topics of: communication with f

94 rong or weak recommendations and to classify levels of evidence as high, moderate, low, or very low.

95 ces as well as surgeons with an intermediate level of experience showed improvement in OR performance

96 One of four radiologists with different levels of expertise (1-9 years) first reviewed only a fr

97 These results, in combination with the high levels of exposure, indicate a potentially serious human

98 ESCd display a high level of expression of genes implicated in migration and

99 nts after SIV infection and suggest that the level of expression of restriction factors may contribut

100 age to have a lower CpG content and a higher level of expression.

101 Ps, PPKs and mechanoreceptors had consistent levels of expression in all libraries.

102 in cell culture was inversely related to the levels of expression of GRP78 and that both proteins int

103 etabolism is brought about by changes in the levels of expression of relatively few genes, but this i

104 vely correlated with diabetes prevalence and levels of fasting and 2-hour glucose (each P < 0.008).

105 edicted jointly by low levels of SA and high levels of FCA-that is a level of SA lower than would be

106 1 is essential for maintaining physiological levels of Fe/S cluster biogenesis proteins during iron d

107 uld indicate very low detection limit to the level of few molecules, a realistic possibility.

108 enic indices, markers of inflammation, serum levels of fibroblast growth factor 21 (FGF21), and activ

109 Indeed, protein levels of fibrosis signaling mediator TGF-beta remained

110 Plasma levels of fitusiran increased in a dose-dependent manner

111 agronomic production systems may affect the levels of food metabolites.

112 etween measurements of OVOCs, including high levels of formic acid, in the atmosphere (measured by an

113 signature measuring the relative expression levels of four host messenger RNAs, was developed to dis

114 Expression levels of four novel GAD1 transcripts (8A, 8B, I80 and I

115 en accompanied by dyslipidemia with elevated levels of free fatty acids (FFAs).

116 els are required that maintain physiological levels of FUS expression and that recapitulate the human

117 irm that PVPP does not interact with OTA and levels of gallic acid and catechin remaining in pistachi

118 of patients, our study revealed that higher levels of gamma-OHPdG are strongly associated with low s

119 increased by a factor of 4 by physiological levels of gap junctional coupling between sister MCs at

120 oefficient of gene differentiation (Gst) and level of gene flow (Nm) revealed by ISSR were 0.4498, 0.

121 However, their arguments are based on a level of generality that fails to appreciate the specifi

122 We show that gAHB retains high levels of genetic diversity after evolution of gentle be

123 The residual levels of GINS1 activity reached 3% to 16% in patients'

124 LL4 in cancer cells decreased the expression levels of Glut1 and inhibited glycolysis in cancer cells

125 our objectives were to determine and compare levels of glutathione, as well as ergothioneine, in diff

126 e observed that in drought-responsive genes, levels of H2A.Z in the gene body correlate with transcri

127 for the simultaneous determination of trace levels of heavy metal ions by anodic stripping voltammet

128 However, how relative levels of hepatocyte and cholangiocyte gene expression a

129 t individuals over 90 years old carried low levels of heteroplasmic variants in their genomes.

130 Endurance training increased the basal mRNA level of hexokinase-2, hormone sensitive lipase, glutath

131 Strong product binding and high levels of holo-ACPP in the cell identify a potential reg

132 arasite virulence and genetically determined levels of host-plant resistance and tolerance.

133 o dog and cat allergens in DCC often reached levels of households with pets.

134 To test this, we measured the levels of Idh1-GFP, Idh2-GFP, Trx2-GFP, Pdr5-GFP and Can

135 The level of IFNAR1*557Gluext*46 mutant protein expressed in

136 re is a strong link between CSU and elevated levels of IgG antithyroid autoantibodies (AAbs), with mo

137 rnal and cord serum samples were assayed for levels of IgG1 and IgG3 specific for MSP119, MSP2 (both

138 ouse models of autoimmunity, increased serum levels of IgM anti-histone H2A autoantibodies significan

139 High levels of IL-10 and IL-12/23p40 were significantly assoc

140 iven by pathogenic T cells that produce high levels of IL-17 in response to IL-23.

141 deficient murine macrophages produce reduced levels of IL-18 and are unable to optimally stimulate IF

142 IL-10 were significantly decreased, and the levels of IL-2 in the serum of AOM rats increased after

143 D), are associated with a marked drop in the levels of important neurotransmitters, such as acetylcho

144 There were lower levels of in vitro-polarized TH2 cells from Spi2A knocko

145 mosterol in the HSV envelope support similar levels of infectivity.

146 increase in number and changes in expression levels of inflammation-related genes, monitored by both

147 levels of viremia were similar, however, the levels of inflammatory cytokines and MDSC were more pron

148 diseases has been associated with increased levels of inflammatory cytokines, including tumor necros

149 The mean levels of influenza viral RNA shedding in asymptomatic a

150 zation methods to improve separation and the level of information obtained from a single analytical s

151 There was no significant difference in the levels of inhibition of UVB-induced immunosuppression am

152 ced insulin sensitivity, and low circulating levels of insulin and insulin-like growth factor 1 (IGF-

153 Levels of interleukin (IL)-13 in BAL were also significa

154 Levels of interleukin 23 (IL23) and T-helper (Th) 17 cel

155 This need associated with serum levels of IS independent of renal function.

156 Indeed, RIMA knockdown reduces the nuclear levels of IYO and prevents its prodifferentiation activi

157 tion to asparaginase, yet surprisingly, mRNA levels of key ISR gene targets such as Atf5 and Trib3 fa

158 hest concentrations of HIV-1 RNA and highest levels of Ki67 expression.

159 Greater levels of late/early ejection-phase MWS were associated

160 iscussion and interest, with the most likely levels of least resistance being the interdigitation zon

161 atectomy without prior radiotherapy at a PSA level of less than 1 ng/mL.

162 Increased levels of leukocytes, platelets, and tissue factor-posit

163 We examined levels of liver fat, lipogenic indices, markers of infla

164 her total drinks in the past 30 days, higher levels of LPS, sCD14 and sCD163.

165 STIs reported were low commitment by higher levels of management, few recent STI-focused trainings,

166 In this study, we identified elevated levels of matrix metalloproteinase (MMP)-12 in gingival

167 ffect of vasopressin is not dependent on the level of maturation (depolarizing vs. hyperpolarizing) o

168 onal bias and ultimately leads to an unusual level of microstructural plasticity, raising the questio

169 and adult leaves correlated positively with levels of miR156, a major regulator of VPC in plants, an

170 The sensors can determine relative levels of miRNAs in total RNA extracts with sensitivity

171 be included in our analysis because of high levels of missing data.

172 In individual tumors, levels of MMP2 and MMP13 correlated more closely with le

173 omplex macromolecule synthesis, where a high level of molecular precision or monomer sequence control

174 Because these diseases have high levels of morbidity and can be lethal, it is important t

175 e expression is extensively regulated at the levels of mRNA stability, localization and translation.

176 We also found that transcript levels of MSN2/MSN4 are increased in glucose-depletion c

177 udies suggest that maintaining physiological levels of mTORC1 signaling is essential for postnatal te

178 led to high expansion activity and elevated levels of MutSbeta complex, indicating that MutSbeta abu

179 To investigate the levels of neutrophil elastase (NE), matrix metalloprotei

180 y or NRT-only use may obtain roughly similar levels of nicotine compared with smokers of combustible

181 The level of nitrogen (N), phosphorus (P), zinc (Zn), iron (

182 ically, loss of UNC-45A results in increased levels of NMII activation.

183 r functionalities that provide a therapeutic level of NO necessary to promote angiogenesis and to pro

184 er, the optimal solutions depend on both the level of noise and how it impacts a particular computati

185 Levels of NR1D1 were knocked down with small hairpin RNA

186 plantagineum possessed significantly higher levels of numerous pyrrolizidine alkaloids involved in p

187 Resting levels of O2 in the rodent brain varied between 6.6 +/-

188 The increase in the level of O3 was associated with an increased mixing rati

189 Cellular and secreted levels of OEA and PEA (P < 0.001-0.001) were increased i

190 e transcriptomic and genomic analysis at the level of one single plant cell type, the root hair cell,

191 f programmed cell death protein 1 and a high level of OX40 were associated with reduced patient survi

192 and USP10, which are involved in regulating levels of p53 and MDM2.

193 is not the only element responsible for the level of PAPhy_a expression during grain maturation.

194 ieved that RASopathies are caused by altered levels of pathway activation, the signaling changes in d

195 To compare the circulating plasma levels of peptide YY and ghrelin in control subjects and

196 abolic stress in response to DSS with higher levels of phospho-AMPK and lower levels of phosphorylati

197 t PP1alpha inhibition increases steady-state levels of phosphorylated MEK1/2 in various tumor cells e

198 r chondrocytes and synovial cells and reduce levels of phosphorylated VEGFR1 in dorsal root ganglia.

199 F antibodies suppress OA progression, reduce levels of phosphorylated VEGFR2 in articular chondrocyte

200 with higher levels of phospho-AMPK and lower levels of phosphorylation of mammalian target of rapamyc

201 When levels of PI3-kinase activity and/or DE-Cadherin are red

202 ies with both high mean phenotype values and levels of plasticity that are appropriate for the target

203 mutant is accompanied by a reduction in the levels of polycomb repressive complex 2 (PRC2)-mediated

204 Higher levels of sodium and lower levels of potassium intake are associated with higher bl

205 ion between the prevalence of low VA and the levels of PP.

206 Levels of PP5 were increased in ASM cells from severe as

207 Plasma levels of PPi and the degree of ectopic mineralization w

208 gn is flexible enough to accommodate varying levels of pretrial biomarker confidence within the same

209 An appropriate level of process description is crucial to constructing

210 spruce will contribute to maintaining a high level of productivity across many Central European mount

211 CD8(+)RORgammat(+) T cells expressing a low level of programmed cell death protein 1 and a high leve

212 Increased level of proinflammatory cytokine interleukin (IL)-12 co

213 acid changes (pH1N1/NSs-6mut) induced lower levels of proinflammatory cytokines, resulting in viral

214 otection against the same natural enemy, the level of protection corresponded to the higher of the tw

215 h aimed at addressing these questions at the level of psychological process and neural mechanism, exa

216 ation respectively, which we use to tune the levels of Raf/MEK/ERK signaling.

217 aptic transmission correlates with increased levels of Ras homolog gene family, member A (RhoA), a KC

218 caused by increased, as well as attenuated, levels of Ras signaling.

219 ]/[OH]) and increased [NO2]/[NO] with higher levels of RBS and/or RIS.

220 of the Lipa gene in mice decreased the liver levels of RE, most likely as the result of a gradual dis

221 ch counteract the effects of relatively high levels of reactive oxygen species.

222 city and translucency of surfaces arise at a level of representation where 3D shape is made explicit.

223 resence of C5 inhibitors correlated with the levels of residual hemolysis.

224 68%) of 44 individual patients had different levels of responses within the M1 and M2 clones.

225 Human cardiomyocytes exhibit two levels of resting membrane potential at subphysiological

226 Similarly, serum levels of retinol-binding protein 4 and retinoids were s

227 inearly (p<0.05) by raising the substitution levels of rice with ASF.

228 a range of colloid sizes to glass with three levels of roughness was examined under both favorable (e

229 MMP2 and MMP13 correlated more closely with levels of S100A4, whereas MMP9 levels correlated more cl

230 evels of SA and high levels of FCA-that is a level of SA lower than would be predicted from the FCA.

231 the first, risk was predicted jointly by low levels of SA and high levels of FCA-that is a level of S

232 In this study, the level of sanitation access of surrounding households was

233 ulations are increasingly carried out at the level of scaffolds rather than compounds, and scaffold q

234 It is paramount to apply a strong level of scientific rigor toward a well-planned, step-wi

235 sacpd-c mutants were identified to have high levels of seed, nodule, and leaf stearic acid content.

236 -34-Mphis possess significantly greater mRNA levels of select restriction factor genes than CSF-1-Mph

237 The uptake carrier exhibits a very high level of selectivity towards small substrates including

238 BS (with visceral hypersensitivity or normal levels of sensitivity).

239 PR infants exhibited higher levels of separation anxiety and arousal in response to

240 el to understand the significance of altered levels of SERCA, IP3R, and RyR on the intracellular calc

241 ium dynamics can be modified by changing the levels of SERCA, IP3R, and/or RyR.

242 infected Irgm1-deficient mice displayed high levels of serum cytokines typifying profound autoinflamm

243 Imatinib also reduced levels of serum tryptase, a marker of mast-cell activati

244 d in both mouse models it normalized protein levels of several SCA2-related proteins expressed in Pur

245 ng replicate wild populations with differing levels of sexually antagonistic selection for colour, we

246 piriform cortex, with robust effects at the level of single trials.

247 rative colitis expressed significantly lower levels of SIRT1 mRNA than controls.

248 Since the significantly higher levels of SIV infection in SLOs occurred with a massive

249 Inflammation was associated with low levels of SIV RNA in the brain as shown by in situ hybri

250 Higher levels of sodium and lower levels of potassium intake ar

251 The expression levels of some markers for AML subtypes and c-MYC regula

252 Consistently, restoring high levels of SOX5/6/21 in human primary glioblastoma cells

253 al syntheses, a synthesis that combines high levels of step economy with high levels of efficiency an

254 ransplanted over 11 y ago showed the highest levels of Streptococcus (18.4%), Haemophilus (12.7%) and

255 ineffective (nifH) nodules, particularly low levels of sucrose were observed, suggesting that plant s

256 ingly, C. cohnii was characterised by a high level of sulfur compounds (dimethyl sulfide, ethanethiol

257 inary team training scenario with 3 possible levels of surgical realism: (1) SimMan (Laerdal) (contro

258 nts of how negative images are formed at the level of synaptic plasticity rules, cells, and circuits.

259 mly assigned in a factorial design to target levels of systolic blood pressure (130-149mmHg vs <130mm

260 The expression levels of tau and TDP-43 were inverse in the frontal cor

261 Interestingly, the relative expression levels of Tau isoforms containing either 3 (3R-Tau) or 4

262 so expressed granzymes, IL-13, and increased levels of Tbet.

263 Ecological theory predicts that high levels of temporal autocorrelation in the environment -

264 NA hypermethylation and its elevation of the levels of TET enzyme, which is responsible for DNA demet

265 (+) regulatory T cells, while decreasing the levels of Th17 cells in vivo, indicating that CCR2 regul

266 oth at individual partition level and at the level of the global concentration.

267 pha-syn cells, aggregation is reduced to the level of the parental cells.

268 nformation from multiple senses, even at the level of the primary sensory areas.

269 nt from 41% to 16%, while gatekeeping at the level of the township hospital would retain correct mana

270 ne monophosphate (cGMP) leading to increased levels of the cAMP response element binding protein (CRE

271 Circulating monocytes uniformly express high levels of the canonical E-selectin binding determinant s

272 dent neural input, originated from different levels of the central nervous system, to the different c

273 s effect is accompanied by higher expression levels of the gibberellic acid (GA) catabolic enzyme StG

274 The expression levels of the immature-like neutrophil signature increas

275 In addition, the levels of the immunomodulatory cytokines IL-1alpha and I

276 ls are prone to seizures and have high brain levels of the inflammatory cytokine IL-1beta.

277 es, we find that cancer cells depend on high levels of the iron-sulfur cluster biosynthetic enzyme NF

278 Protein levels of the kinase SGK1 did not change.

279 is highly nutritious but contains very high levels of the non-threshold carcinogen inorganic arsenic

280 f DM and the glycosylated hemoglobin (HbA1c) levels of the patients in the DM group were recorded.

281 Two levels of the pore conductance and two dwell closed time

282 RNAseq analysis revealed the highest levels of the Ss-riok-2 transcript in free-living female

283 ed to determine whether changes in the serum levels of these noncoding RNAs are observed in patients

284 obesity increased miR-126 expression however levels of this miR were not influenced by a post-weaning

285 ugt80A2 mutants exhibit significantly lower levels of total SGs they are morphologically indistingui

286 down immortalized mouse podocytes had higher levels of toxic glucose metabolites, mitochondrial dysfu

287 to high and low concentrations of CO2 at the level of transcripts, proteins and enzyme activity.

288 mate associations with first-trimester serum levels of triglycerides, total cholesterol, and C-reacti

289 We aimed to systematically evaluate serum levels of tryptophan and its metabolites in patients wit

290 sions in biopsy specimens or persistent high levels of tTGA.

291 5 deficiency also leads to persistently high levels of type I IFN-stimulated gene expression and to i

292 duce defective CD11b associate with elevated levels of type I interferon (IFN-I) in lupus, suggesting

293 rs to these questions will provide a greater level of understanding of miRNA biology and critical ins

294 elt event in two watersheds with contrasting levels of urbanization.

295 parameters to make predictions shows a high level of variability in the modelled number of pandemics

296 Furthermore, levels of VEGF-D and MCP-1 in patient sera correlated po

297 of managed referral with gatekeeping at the level of village clinics would reduce proportions of cor

298 Acute and post-cART levels of viremia were similar, however, the levels of i

299 r sequences for the generation of functional levels of VSG expression in bloodstream form T. brucei.

300 sed in patient fibroblasts was comparable to levels of WT IFNAR1 in control fibroblasts.