ライフサイエンスコーパス: licensing factor

1 ication origins as a coactivator of the Cdt1 licensing factor.

2 ing frame of a gene encoding DNA replication licensing factor.

3 ts that led to the proposal of a replication licensing factor.

4 family of proteins that comprise replication licensing factor.

5 UL-4 independently controls both replication-licensing factors.

6 is an essential component of DNA replication licensing factor, a hexameric protein complex that regul

7 s on the temporal restriction of replication licensing factor activity.

8 l cycle progression that targets replication licensing factors, also targets the p12 subunit of Pol d

9 x (also known as MCM2-MCM7), the replication licensing factor and presumptive replicative helicase.

10 rmally high levels of replication and origin licensing factors and are likely poised for genome re-re

11 plex, replication factor C proteins, MCM DNA-licensing factors and the bacterial DnaA, RuvB, and McrB

12 ulate DNA replication and that components of licensing factor are targets of the products of tumor su

13 tration that cellular replication and origin licensing factors are required for KSHV latent cycle rep

14 Replication-licensing factors are required to form prereplicative co

15 nome encodes two homologs of the replication licensing factor CDC10 Target1 (CDT1), and overexpressio

16 events the nuclear export of the replication-licensing factor Cdc6 during S phase, and the block on n

17 The replication licensing factor CDC6 recruits the MCM2-7 replicative he

18 ow that CDK phosphorylation of the essential licensing factor Cdc6 stabilizes it by preventing its as

19 ted by concomitant downregulation of the DNA licensing factor cdc6.

20 The replication-licensing factors Cdc6 and Cdt1 are required for the ass

21 nated activation of both an essential origin licensing factor, CDC6, and an activity required for ori

22 UBXN-3/FAF1 binds to the licensing factor CDT-1 and additional ubiquitylated prot

23 E3 ubiquitin ligase include the replication licensing factor Cdt1 and the cyclin-dependent kinase (C

24 Several proteins, including the replication licensing factor CDT1 and the histone methyltransferase

25 ation, in part, by degrading the replication-licensing factor Cdt1 during S phase.

26 Knockdown of the replication origin-licensing factor CDT1 eliminates both stress-induced rer

27 have been reported to target the replication licensing factor Cdt1 for ubiquitin-mediated proteolysis

28 The DNA replication licensing factor Cdt1 is degraded by the ubiquitin-prote

29 Proper expression of the replication licensing factor Cdt1 is primarily regulated post-transl

30 The C. elegans orthologue of the replication-licensing factor Cdt1 is required for DNA replication.

31 cle-regulated degradation of the replication licensing factor Cdt1 plays important roles in preventin

32 Geminin interacts with the licensing factor Cdt1 to prevent untimely replication an

33 in a manner that depends on the replication licensing factor Cdt1, but is independent of the Cdt1 re

34 h predominantly inhibits the DNA replication licensing factor Cdt1, preventing genome over-replicatio

35 atin during G1 phase and is dependent on the licensing factor Cdt1.

36 ession, including a critical DNA replication licensing factor CDT1.

37 ase, is a coactivator of the DNA replication licensing factor Cdt1.

38 replication induced by overexpression of the licensing factor Cdt1.

39 the recruiting transcription and replication licensing factors coordinates the transcriptional and DN

40 ), at Y32, which then phosphorylates MCM7, a licensing factor critical for DNA replication, at Y600 t

41 in the endocycle have reduced levels of the licensing factor Double Parked/Cdt1 (Dup/Cdt1), as well

42 inhibits the accumulation of the replication-licensing factor Doubleparked/Cdt1 (Dup/Cdt1).

43 s, nucleocytoplasmic compartmentalization of licensing factors ensures that DNA replication occurs on

44 ental observations suggest that AR becomes a licensing factor for DNA replication in AS prostate canc

45 in vivo, consistent with AR functioning as a licensing factor for DNA replication in AS prostate canc

46 regulator of G1-S progression and possibly a licensing factor for DNA replication yet the mechanisms

47 -S progression, possibly by functioning as a licensing factor for DNA replication.

48 al cells, in which AR does not function as a licensing factor for DNA replication.

49 nsor for siRNA thermodynamic asymmetry and a licensing factor for entry of authentic siRNAs into the

50 hen present on the chromatin, may serve as a licensing factor for estrogen-ESR1-mediated interactions

51 cus, the present results establish PTIP as a licensing factor for humoral immunity that acts at sever

52 MCM7 is one of the pivotal DNA replication licensing factors in controlling DNA synthesis and cell

53 Cdt1 DNA replication licensing factor is part of the pre-replication complex

54 covered a single phosphorylation site in the licensing factor M18BP1 and a cyclin A binding site in t

55 ) encodes a homologue of the DNA replication licensing factor Mcm7, a highly conserved protein found

56 in with hypomorphic expression of the origin licensing factor mini-chromosome maintenance (MCM)3 that

57 unreplicated from replicated DNA, as in the licensing factor model.

58 easomal degradation of Cdt1 (DNA replication licensing factor), p21 (cyclin-dependent kinase [CDK] in

59 by depleting Cdt1, an essential replication licensing factor, partially rescued emi1 deficiency-indu

60 resence of a soluble form of the replication-licensing factor (RLF) Cdc6, inhibits initiation of cell

61 Replication licensing factor (RLF) is an essential initiation factor

62 Replication licensing factor (RLF) is involved in preventing re-repl

63 that prevent the association of replication licensing factor(s) with the DNA.

64 -activated JNK kinases and also for the Cdt1 licensing factor that ensures that DNA is replicated exa

65 As such, Htm1p-Pdi1p is suited to act as a licensing factor that monitors folding in the ER lumen a

66 s work alters our view of how ATP is used by licensing factors to assemble pre-RCs.

67 The enforced expression of these two licensing factors was sufficient to restore the assembly

68 ion (MBT), including a marked decline of the licensing factor XCdc6.