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   1 ta reinforces evidence for T2D prevention by lifestyle intervention.                                 
     2 etary intake and weight loss during an 18-mo lifestyle intervention.                                 
     3 ho remain with prediabetes despite intensive lifestyle intervention.                                 
     4 investigated in 50 participants undergoing a lifestyle intervention.                                 
     5 d blood pool scans at baseline and after the lifestyle intervention.                                 
     6 o identify NASH resolution in patients under lifestyle intervention.                                 
     7 n without fibrosis worsening after 1 year of lifestyle intervention.                                 
     8 al outcomes in 200 GD patients enrolled in a lifestyle intervention.                                 
     9 universal rather than targeted approaches to lifestyle intervention.                                 
    10 rely achieve long-term weight loss with only lifestyle interventions.                                
    11 ul in losing or maintaining weight loss with lifestyle interventions.                                
    12 idities that appear resistant to traditional lifestyle interventions.                                
    13 ac procedures, and discharge medications and lifestyle interventions.                                
    14 ement is best addressed by pharmacologic and lifestyle interventions.                                
    15 ulate primary prevention strategies based on lifestyle interventions.                                
    16 cardiovascular risk and greater benefit from lifestyle interventions.                                
    17 sociated with HDL-C increases with intensive lifestyle intervention (0.0037) and had a nominal treatm
  
    19 o treatment groups during DPP (736 intensive lifestyle intervention, 647 metformin, 607 placebo).    
  
  
    22 estyle changes, and (3) outcomes of previous lifestyle interventions aimed at improving health within
    23 e the effectiveness of drug, supplement, and lifestyle interventions aimed at preventing fracture, im
    24  during a 2-year period in response to three lifestyle interventions, all delivered by PCPs in collab
  
  
  
  
    29 reduced more in the surgical groups than the lifestyle intervention-alone group, with 65% of RYGB, 33
  
  
    32 an intervention to motivate involvement in a lifestyle intervention among people with increased cardi
    33 mparative effectiveness of psychological and lifestyle interventions among COPD patients is not known
  
    35 rences can be observed in the effects of the lifestyle interventions among subgroups defined by basel
    36  QALY was approximately 1100 dollars for the lifestyle intervention and $31 300 for the metformin int
    37 DL-C and triglyceride changes with intensive lifestyle intervention and a treatment interaction (P<0.
    38 levated transaminases in GD independent of a lifestyle intervention and despite a significant reducti
  
    40 /yes), with no differences between intensive lifestyle intervention and diabetes support and educatio
  
  
  
    44 y who are unable to reduce successfully with lifestyle intervention and pharmacotherapy are eligible 
  
    46 ective secondary prevention with appropriate lifestyle interventions and evidence-based medical thera
  
  
  
    50  Older cancer survivors respond favorably to lifestyle interventions and make durable changes in DQ a
    51 in weight and other factors due to intensive lifestyle intervention) and "exhaustion of susceptible" 
    52 help clinicians counsel patients to consider lifestyle interventions, and should fuel research of oth
    53 nefits, diets for weight loss, comprehensive lifestyle intervention approaches, and bariatric surgery
  
  
    56 ssessed whether complex psychological and/or lifestyle interventions are effective in reducing sympto
  
    58 sical activity in cancer survivors; however, lifestyle interventions are not a routine part of cancer
  
    60 rovide further justification for adoption of lifestyle interventions as public health measures to con
  
  
    63  nominal interactions with the metformin and lifestyle interventions at 91 and 69 mostly nonoverlappi
  
  
  
    67 isease is unknown, as is the extent to which lifestyle intervention can alter the course of progressi
    68  research, the strategic and precise role of lifestyle intervention can be fashioned to improve CV ou
  
  
  
    72 a societal perspective, the cost/QALY of the lifestyle intervention compared with doing nothing would
    73 diabetes diagnosed for less than 10 years, a lifestyle intervention compared with standard care resul
    74 on combining a specific compound and several lifestyle interventions compared with placebo for the pr
  
  
    77 of 6 months of high-intensity, comprehensive lifestyle intervention, consisting of a reduced-calorie 
    78 m effectiveness of a randomized, tailor-made lifestyle intervention, consisting of diet and exercise,
  
  
    81  Metformin, 850 mg twice daily, or intensive lifestyle intervention designed to achieve and maintain 
    82 tein can be used to target pharmacologic and lifestyle interventions designed to prevent first as wel
  
  
    85 etabolic syndrome, the desirable approach is lifestyle intervention, especially weight reduction and 
    86 ared GH therapy with no GH therapy or GH and lifestyle interventions (exercise with or without diet) 
  
  
    89 ervention for 1 year followed by a low-level lifestyle intervention for 2 years or surgical treatment
    90 emphasise the long-term clinical benefits of lifestyle intervention for patients with impaired glucos
    91   Therefore, maternal exercise is a powerful lifestyle intervention for preventing maternal HFD-induc
    92 counterbalanced the beneficial effect of the lifestyle intervention for the special intervention grou
  
    94 ed controlled trials of psychological and/or lifestyle interventions for adults with COPD that measur
  
  
    97 plore the use of goal setting within healthy lifestyle interventions for the prevention of excess GWG
  
    99 quality-adjusted life-year (QALY) of the DPP lifestyle intervention from the health plan's perspectiv
  
   101 aseline by 0.25 (-2.25 to 2.23) units in the lifestyle intervention group, and by 1.08 (-3.25 to 1.86
   102 e ratio (T/S)units (IQR-0.05 to 0.11) in the lifestyle intervention group, but decreased in the contr
  
  
  
   106 e randomised (1:1:1:1) to a control group or lifestyle intervention groups (diet or exercise or both)
   107  to 2.70; P=0.004) than in the metformin and lifestyle-intervention groups (hazard ratios, 1.62 and 1
   108  months of participation in a high-intensity lifestyle intervention (>/= 14 treatment visits) consist
   109  identified randomized, controlled trials of lifestyle interventions (>/=3 months' duration) that inc
   110 tion in DPP, those assigned to the intensive lifestyle intervention had a higher diabetes risk (HR 1.
   111 nts with type 2 diabetes undergoing a 1-year lifestyle intervention had significant improvements in G
   112 l blood glucose and concluded that intensive lifestyle interventions have a moderate benefit in reduc
   113 past three decades, both pharmacological and lifestyle interventions have been studied for the preven
  
  
   116 n 1993 and 2003, and randomised to intensive lifestyle intervention (I) or lifestyle advice control (
  
   118   We investigated whether a 1-year intensive lifestyle intervention (ILI) for weight loss would avert
   119 res (GRS), metformin treatment and intensive lifestyle intervention (ILI) given a range of sampling f
   120  trial and randomly assigned to an intensive lifestyle intervention (ILI) or diabetes support and edu
   121 ollow-up, April 2008) comparing an intensive lifestyle intervention (ILI) with a diabetes support and
   122  trial to determine the effects of intensive lifestyle intervention (ILI), including weight loss and 
  
  
   125 y that is provided by a dietitian as part of lifestyle intervention in type 2 diabetes, but further r
  
  
  
   129      Adverse events that were related to the lifestyle intervention included a slightly higher freque
   130 rograms involved an intensive, family-based, lifestyle intervention, including exercise, nutritional 
  
  
  
  
   135  active surveillance, together with diet and lifestyle intervention, is appropriate for many older me
   136 besity treatment, when used as an adjunct to lifestyle intervention, lead to greater mean weight loss
  
  
  
   140 ndomized in a 2:1 ratio to receive intensive lifestyle intervention (LS) or structured education (con
   141 atients unable to reduce satisfactorily with lifestyle intervention may be candidates for pharmacothe
  
  
   144 ctors, suggesting that more focused diet and lifestyle interventions may be needed to improve risk fa
  
   146 s early stage of disease, interventions (eg, lifestyle intervention, medication) can be used to preve
   147 2 years after random assignment to intensive lifestyle intervention, metformin therapy, or placebo.  
   148 Program (DPP), which examined the effects of lifestyle intervention, metformin, and troglitazone vers
   149 hentermine and topiramate, with office-based lifestyle interventions, might be a valuable treatment f
   150 such as education, intensive monitoring, and lifestyle interventions, might be needed, especially for
   151 in obese women who were randomly assigned to lifestyle interventions of either weight loss without ex
   152 is warranted to determine the impact of such lifestyle intervention on improving physical fitness and
  
   154  We examined the effects of a multicomponent lifestyle intervention on weight loss and prevention of 
  
   156 were to study the effect of 2 multicomponent lifestyle interventions on estimated CHD risk relative t
   157  key component mediating salutary effects of lifestyle interventions on hyperglycemia and insulin res
  
   159 CI) with intensive pharmacologic therapy and lifestyle intervention (optimal medical therapy) is supe
   160  with type 2 diabetes to either an intensive lifestyle intervention or a diabetes support-and-educati
  
   162 pants were randomly assigned to an intensive lifestyle intervention or to enhanced usual care (a diab
   163 in the Diabetes Prevention Program, in which lifestyle intervention or treatment with metformin was c
   164 rection of 'modifiable risk factors' through lifestyle interventions or medication would be most bene
   165 ssociated with greater weight loss following lifestyle intervention over 4 years across the DPP and L
  
   167 sociated with HDL-C increases with intensive lifestyle intervention (P=0.0038 and 0.013, respectively
   168 ction test for normal glucose regulation and lifestyle intervention, p=0.1722; normal glucose regulat
  
  
   171 -related comorbidities produced by intensive lifestyle intervention, pharmacotherapy, and bariatric s
  
  
   174 ight in meters) of 29 or higher to a 6-month lifestyle intervention preceding treatment for infertili
   175 etformin groups were offered group intensive lifestyle intervention prior to entering the DPPOS.     
   176 oved for long-term use, when prescribed with lifestyle interventions, produce additional weight loss 
   177 d with rosiglitazone (4 mg twice a day) or a lifestyle-intervention program focusing on weight loss t
  
   179 thesized that modifying these factors with a lifestyle-intervention program or the administration of 
   180 tegies: 290 women were assigned to a 6-month lifestyle-intervention program preceding 18 months of in
   181 6.9 persons would have to participate in the lifestyle-intervention program, and 13.9 would have to r
  
  
   184  lifestyle modification; however, successful lifestyle intervention programmes are labour intensive. 
  
   186 ncorporation of physical activity with other lifestyle interventions provides multiple benefits to hy
  
  
   189 fy 1-year treatment response to an intensive lifestyle intervention, relative to a usual care of diab
  
  
   192 he beta model implies that medical, diet, or lifestyle interventions restricting carcinogenesis ought
   193 gery with 2 years of an adjunctive low-level lifestyle intervention resulted in more disease remissio
   194 ght/obese individuals with T2D and whether a lifestyle intervention resulting in weight loss could di
  
   196 h as low-dose aspirin, calcium, and diet and lifestyle interventions, show potential but small benefi
   197 demonstrated that, compared with usual care, lifestyle intervention significantly reduced progression
  
   199 in C supplementation represents an effective lifestyle intervention strategy for improving endothelia
  
  
   202  (n=1411) data participating in a randomized lifestyle intervention study for weight loss, Action for
   203      To lower risk of early AMD, recommended lifestyle interventions such as the avoidance of smoking
  
   205 urrent epidemic of obesity and the fact that lifestyle interventions, such as weight loss and exercis
  
   207 ti-Alzheimer's therapy will be combined with lifestyle interventions targeting general brain health t
  
   209 pe 2 diabetes to participate in an intensive lifestyle intervention that promoted weight loss through
  
  
  
   213 evidence for alternative pharmacological and lifestyle interventions that may improve vascular functi
  
   215 ects and in the latter group after 1 year of lifestyle intervention (the Look AHEAD [Action For Healt
  
   217 rates, but not the availability of intensive lifestyle intervention to all persons before the beginni
   218 t that estimated the per capita costs of the lifestyle intervention to exceed that of the usual care 
   219  a precision medicine approach through early lifestyle intervention to offset the impact of blood pre
   220 er summarizes scientific evidence supporting lifestyle intervention to prevent type 2 diabetes and di
  
   222   The preschool period is a pivotal time for lifestyle interventions to begin the establishment of lo
  
  
   225 nmark; they had previously completed a 68-wk lifestyle intervention trial and achieved an average wei
  
  
   228 d controlled trial to examine the effects of lifestyle intervention using a combination of diet, exer
  
   230 odify the effects of metformin treatment and lifestyle intervention (versus placebo control) on lipid
  
   232  analyses of overweight adults, an intensive lifestyle intervention was associated with a greater lik
  
  
   235 pecial intervention group smokers, while the lifestyle intervention was beneficial among nonsmokers. 
  
   237 to metformin alone (P=0.006); metformin plus lifestyle intervention was intermediate but not signific
   238  of diabetes in persons at high risk and the lifestyle intervention was more effective than metformin
  
   240 % CI: 17 to 43%), compared with placebo; the lifestyle intervention was significantly more effective 
   241 o 43 percent), as compared with placebo; the lifestyle intervention was significantly more effective 
   242 ition of rosiglitazone, but not an intensive lifestyle intervention, was superior to metformin alone.
  
  
   245 d participated in an intensive nutrition and lifestyle intervention while undergoing careful surveill
   246 ive set of community-based, widely available lifestyle interventions, with optional partner participa
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