ライフサイエンスコーパス: ligand for

1 " platform to identify and validate covalent ligands for 11 different human proteins.

2 s establish macropa to be a highly promising ligand for (225) Ac chelation that will facilitate the c

3 glycerol, and glycerol phosphate as specific ligands for 4E10 in the crystal structures.

4 terone (DHEA) regulates gene expression as a ligand for a G-protein-coupled receptor and as a precurs

5 Determining the affinity of a ligand for a given protein is a crucial component of dru

6 anic molecule to function as a physiological ligand for a nuclear receptor and direct environmental s

7 monolayer that presents a candidate peptide ligand for a receptor and a peptide substrate for an enz

8 Interestingly, hybrubin A was found to be a ligand for a variety of GPCRs with a propensity for pote

9 QM has been used for the ligand, for a few crucial groups around the ligand, for

10 First, different ligands for a given TAAR can vary in behavioral effect.

11 along with the implementation of the BI-DIME ligands for a ligand-controlled Suzuki cross-coupling an

12 ity, and the cysteines are shown to serve as ligands for a single, critical Zn(2+) ion.

13 oparticles can be conjugated to high-avidity ligands for a variety of cellular targets.

14 PET ligands for Abeta protein are increasingly used in diagn

15 n NB, neither drug reduced the expression of ligands for activating NK receptors or upregulated that

16 g NK cell function in which NK cells acquire ligands for activating receptors from target cells by tr

17 Here we report new classes of ligands for acylboronates that have a significant influe

18 ose naming augmentor-alpha (AUG-alpha), as a ligand for ALK.

19 ierarchy and specificity of two cytokines as ligands for ALK and LTK and set the stage for elucidatin

20 Both Univin and Nodal are potential ligands for Alk4/5/7; however, Nodal is unilaterally exp

21 ligand, for a few crucial groups around the ligand, for all the closest atoms (200-1000 atoms), or f

22 T cell epitopes enabled us to identify pMHC ligands for all five of the groups tested.

23 Thus, NK cell acquisition of a ligand for an activation receptor by trogocytosis render

24 tructures and comparative models to identify ligands for an allosteric peptide-binding site on the pr

25 to identify endogenous and viral MHC class I ligands for any bat species and, as such, provides an im

26 lize to the host outer membrane and serve as ligands for apical membrane antigen (AMA) family surface

27 f the Contactin family function as authentic ligands for APP and its orthologs, and that this evoluti

28 ce that Contactins can function as authentic ligands for APP family proteins that regulate APP-depend

29 uca Contactin (MsContactin) as an endogenous ligand for APPL, consistent with previous work showing t

30 r inner sphere was the most probable type of ligand for arsenate on both phases and for selenate on s

31 story of the development of chiral sulfoxide ligands for asymmetric catalysis.

32 ducts with bitriazole linkers were effective ligands for asymmetric copper-catalyzed Michael addition

33 or 'Privileged chiral N-heterocyclic carbene ligands for asymmetric transition-metal catalysis' by Da

34 e we report the development of PEGylated-NHC ligands for Au-NP surfaces and the first example of NHC-

35 g ligand" (APRIL) is a natural high-affinity ligand for BCMA and transmembrane activator and calcium-

36 nd is shown to be recognized by QueF as weak ligand for binding (DeltaH = -2.3 kJ/mol; -TDeltaS = -19

37 ed indicating the importance of the indazole ligands for binding site recognition and thus their indi

38 beta-catenin signaling by competing with Wnt ligands for binding to Frizzled receptors, as well as by

39 Judicious choice of ligand for both Cu and Pd enabled this hydroarylation pr

40 Alternative PSMA ligands for both imaging and therapy are available.

41 ing number of fluorine atoms on the alkoxide ligands for both molecular and supported catalysts but w

42 rent literature on low-molecular-weight PSMA ligands for both PET imaging and therapeutic approaches,

43 ze the same interactions with specific metal ligands for both structural stability and chemical activ

44 also shown promising results as a targeting ligand for brain delivery using nanoparticles (NPs).

45 reduce possible off-target toxicity of TNFSF ligands for cancer immunotherapy.

46 n and liver, increasing levels of endogenous ligands for cannabinoid and alpha-type peroxisome prolif

47 NTN1, suggesting that CNTN1 is an endogenous ligand for CASPR2.

48 nic side chains of two of the three putative ligands for cation binding (Asp-55 and Asp-59 in helix I

49 al cellular sources of the chemokine CCL2, a ligand for CCR2, included perivascular macrophages and m

50 the site of PNI, but not CCL7, an alternate ligand for CCR2.

51 LLT1 (lectin-like transcript 1), the ligand for CD161a, was overexpressed in SHR kidney, wher

52 activation/differentiation; however, natural ligands for CD33 remain elusive.

53 or component of the extracellular matrix and ligand for CD44.

54 expressed higher amounts of HLA-G, the main ligand for CD85j, than M1.

55 ors parallels the conservation of MHC-E, the ligand for CD94:NKG2A/C/E.

56 ry amines were identified as "ideal" organic ligands for CdSe core nanocrystals to achieve unity radi

57 e possibilities and challenges to find novel ligands for chemokine receptors.

58 are readily tuned by exchange of the OAc(-) ligand for Cl(-) (1-Cl), NO3(-) (1-NO3), and pyridine ([

59 ciation with L-fucose, the potential binding ligand for CL-11.

60 perfringens enterotoxin (cCPE) is a natural ligand for claudin-4.

61 th the discovery of selective, high affinity ligands for CLL BCRs of the aggressive, stereotyped subs

62 encoded by the psbA gene, provides multiple ligands for cofactors crucial to this enzymatic reaction

63 Platelet activation in response to the ligand for collagen receptor glycoprotein VI (cross-link

64 1 bind to C3d and inactivated C3b, which are ligands for complement receptor type 2 (CR2/CD21), the a

65 ns yielded vibrational modes of the diatomic ligands for conceivable H-cluster structures.

66 have the potential to act as a new class of ligands for coordination cages, metal-organic frameworks

67 , we adapted a validated 8-N-benzyladenosine ligand for covalent bond formation and confirmed targete

68 dacnicolor, and validated as a high-affinity ligand for CRF receptor studies.

69 The intracellular nature of the biotic ligand for Cu in microalgal cells was investigated using

70 ceted: besides acting as selective solvating ligands for Cu(+) ions exiting the nanoparticles during

71 glycoproteins bind peptide antigens, forming ligands for cytotoxic T and natural killer cell receptor

72 blocked D8 binding to CS-A, the low affinity ligand for D8.

73 lutinin, a minor peanut allergen, is a novel ligand for DC-SIGN.

74 urified from mycobacteria were identified as ligands for DCAR.

75 Furthermore, non-pathogen-derived ligands for dectin 1 have not been characterized.

76 e link between HCV infection and Netrin-1, a ligand for dependence receptors that sustains tumorigene

77 w how the preferred binding orientation of a ligand for different proteins can be estimated via free

78 is and biological investigations of bivalent ligands for dopamine D2 receptor/neurotensin NTS1 recept

79 ls, indicating that CD43 alone is a dominant ligand for E-selectin.

80 r of natural odor extracts to identify novel ligands for each MP-OSN type.

81 be used to develop selective small molecule ligands for each receptor.

82 To determine whether oxysterol ligands for EBI2 are increased in asthma exacerbation, a

83 DM and PanINs are initiated by high-affinity ligands for EGF-R or activating Kras mutations, but the

84 We report a new chiral pyridinyloxazoline ligand for enantioselective, intramolecular silylation o

85 ient mice implicated IgG as the pathogenetic ligand for endothelial FcgammaRIIB in obesity-induced in

86 Stimulation with ephrinA1, a ligand for EphA2, induced further oligomerization and ac

87 outwardly rectifies when activated by other ligands (for example, pilocarpine and choline).

88 The main ligands for Fe in Tartary buckwheat material were phytat

89 Altogether, these results identify CRP as a ligand for FHR-1 and suggest that FHR-1 enhances, rather

90 hate (S1P) is a sphingolipid and the natural ligand for five G protein-coupled receptors (S1P1, S1P2,

91 S1P is a ligand for five G-protein-coupled receptors, S1PR1 to -5

92 p(2-20) and Ac(2-26), two well-characterized ligands for FPR2 in GC cells.

93 l Review, we describe the development of new ligands for functionalizing and stabilizing metallic gol

94 body approach can generate multiple affinity ligands for future use in norovirus detection and possib

95 erein with examples of enzyme inhibitors and ligands for G protein-coupled receptors.

96 Bile acids are ligands for G-protein coupled receptors (GPCRs) such as

97 Dexamethasone (DEX), a synthetic ligand for glucocorticoid receptor (GR), is routinely us

98 We measured levels of STAT3, P53, ligands for gp130, interleukin 6, cytokines, sonic hedge

99 ever, the absence of endogenous or surrogate ligands for GPR27 complicates the examination of its bio

100 ing oxidized LDL as a representative protein ligand for H2O2-treated CRP, we found that the binding o

101 act as receptors for exosome uptake, but the ligand for heparan sulfate on exosomes has not been iden

102 f normal T cell expressed and secreted), the ligands for HIV entry coreceptor CC chemokine receptor t

103 -volatile compounds (SVOCs) were competitive ligands for human peroxisome proliferator-activated nucl

104 water and CO, thereby providing the carbonyl ligand for hydrogenase.

105 Ligands for identifying protein aggregates are of great

106 high agonist potency as a novel fluorescent ligand for imaging Y4 receptors.

107 vely studied to develop low-molecular-weight ligands for imaging prostate cancer lesions by PET or SP

108 ysts based on MOFs containing nitrogen-donor ligands for important organic transformations.

109 was considered unsuitable as a specific PET ligand for in vivo imaging of mGluR2.

110 s from cell extracts, and as affinity column ligands for inexpensive large-scale protein purification

111 hanisms, including upregulated expression of ligands for inhibitory immune checkpoint receptors.

112 Although the ligands for inhibitory Ly49 were considered to be restri

113 ome encodes for MHC class I-homologous decoy ligands for inhibitory NK cell receptors to evade detect

114 sponse to pathogen molecular mimicry of host ligands for inhibitory receptors.

115 These pathogen lipids are major ligands for innate immune receptors and figure prominent

116 Fibroblast adhesion response to selective ligands for integrins alpha5beta1 and alphavbeta3, which

117 Understanding how to design cell permeable ligands for intracellular targets that have difficult bi

118 ands for open form of alphaIIbbeta3 and four ligands for its closed form followed by their synthesis

119 indicating a beta2-microglobulin-independent ligand for KIR2DS2.

120 e complex immunogenetics and lack of defined ligands for KIRs in non-human primates.

121 Hence, the MHC class I ligands for KIRs in species other than humans are poorly

122 sis in vivo In this study, we identified two ligands for KstR, both of which are CoA thioester choles

123 by requiring overexpression of two separate ligands for localization.

124 However, the range of other proposed ligands for LRC products indicates a dynamic set of rece

125 that MHC-Ib represent an extended family of ligands for Ly49 molecules.

126 a new concept for the quantification of PEG ligands for maleimide-functionalized PEG molecules and t

127 cent advances in the discovery of allosteric ligands for metabotropic glutamate receptor subtypes 1-5

128 that endomorphin-2 (EM2), an arrestin-biased ligand for microR, lengthens surface lifetimes of recept

129 sicochemical properties for a diverse set of ligands for mostly "nontraditional" CNS targets and clas

130 Instead, the high affinity ligand for mouse CD22 has N-glycolylneuraminic acid (Neu

131 xpression of interferon-stimulated genes and ligands for multiple T cell inhibitory receptors.

132 ptide, linTT1 (AKRGARSTA), as a PC targeting ligand for nanoparticles.

133 rrent therapies, repositioning histaminergic ligands for new therapeutic uses, or even including agon

134 ls to probe the VHL-HIF pathways and new VHL ligands for next-generation PROTACs.

135 mmetric catalysis using a chiral bioxazoline ligand for Ni.

136 ic ethers, a reaction that failed with known ligands for Ni and designer phosphines for Pd.

137 ive immune system, function also as the main ligands for NK cell inhibitory receptors, which prevent

138 ling state with broad downregulation of ULBP ligands for NK cells and evasion of NK-cell-mediated cle

139 a1 and alpha2) and is a novel potent agonist ligand for NKG2D.

140 nfected Clr-b-deficient mice, which lack the ligand for NKR-P1B, suggests the involvement of ligands

141 it the first clear candidate for a selecting ligand for non-MHC/CD1-restricted T cells.

142 (68)Ga-HZ220 is a promising bimodal ligand for noninvasive PET imaging and intraoperative op

143 that soluble NE is a specific, high-affinity ligand for NRP1 with a calculated Kd of 38.7 nm Furtherm

144 e metabolite of dietary vitamin A, acts as a ligand for nuclear receptor transcription factors with m

145 isplay experiments to identify all-d peptide ligands for oncogenic KRas, providing a useful tool in t

146 Their screening resulted in four potential ligands for open form of alphaIIbbeta3 and four ligands

147 h a higher affinity than ATP, an established ligand for other USPs.

148 n late-breaking new advances with allosteric ligands for other GPCRs and emerging data for endogenous

149 tase (BACE) inhibitors and also as versatile ligands for other receptor types.

150 oxide is shown to be a hemilabile, bidentate ligand for palladium.

151 ion of BQ, suggesting that BQ is acting as a ligand for Pd(II) which results in an inhibitory effect

152 Tumour cells frequently overexpress the ligand for PD-1, programmed cell death ligand 1 (PD-L1),

153 The discovery of a novel ligand for PDGFRbeta, platelet-derived growth factor (PD

154 ation of (68)Ga-pentixafor, a specific CXCR4 ligand for PET.

155 fluid percussion in adult rats, using 2 new ligands for PET: (18)F-GE-179 for the open/active state

156 a valuable candidate in developing traceable ligands for pharmacological studies of Y4 receptors and

157 of extracellular small-molecule and protein ligands for physiological signaling.

158 hibitor C4b-binding protein, which is also a ligand for PRELP.

159 ptors and now provide evidence that C4a is a ligand for protease-activated receptor (PAR)1 and PAR4.

160 The compounds can also serve as reporter ligands for protein binding studies, as exemplified by s

161 peptoids have been useful in discovering new ligands for protein binding.

162 rk validates the ability of IDUP to discover ligands for proteins of biomedical relevance.

163 The binding affinity of the ligand for PSMA and its internalization properties were

164 ined (18)F-FESCH to be the most suitable PET ligand for quantifying A2A receptor expression in the ra

165 ined (18)F-FESCH to be the most suitable PET ligand for quantifying A2A receptor expression in the ra

166 h affinity ligands compete with low affinity ligands for receptor binding and signaling.

167 ntravascular activator of fibrinolysis and a ligand for receptors involved in cell signaling.

168 eaflet of the plasma membrane functions as a ligand for receptors vital for cell-cell communication.

169 integrity and mediated cytosolic release of ligands for recognition by inflammasome sensors.

170 possible positions; 4) selection of the best ligands for RGD-recognizing integrin subtypes; 5) fine-t

171 led a conspicuously better fit of the corrin ligand for Rh(III) than for Co(III) , challenging the cu

172 of interest has been paid to identifying the ligands for RIG-I under conditions of natural infection,

173 the first comparative view of the viral RNA ligands for RIG-I, MDA5 and LGP2 in the presence of infe

174 nce (SPR) confirmed it to be a high affinity ligand for Robo1.

175 minal sialic acids in targeting glycoprotein ligands for selectins to lipid rafts of leukocytes.

176 inducible protein IRGB10 liberates bacterial ligands for sensing by both the AIM2 and the non-canonic

177 the first one, the affinities of two similar ligands for seven bromodomains were calculated and retur

178 rge hyperglycosylated protein that acts as a ligand for several galectins through glycan-dependent in

179 recognition of targets expressing or lacking ligands for SFRs were enhanced by IL-12 but suppressed b

180 aller dataset containing distinct classes of ligands for SH3 domains, as well as on a new, an order o

181 ed the identity of Muc5b as one glycoprotein ligand for Siglec-F.

182 elopment of persistent carbenes as universal ligands for silicon and potentially other nonmetallic su

183 ified outer membrane protein OprH as a novel ligand for SP-A on P. aeruginosa The last-available (lat

184 Taking advantage of the RNA ligand for specific targeting and extracellular vesicles

185 L-like nanoparticles (HDL NP), high-affinity ligands for SR-B1, to carry a fluorescently labeled phos

186 re modified with biotin, which was used as a ligand for streptavidin (SV) detection.

187 ic carbenes (NHCs) have emerged as versatile ligands for surface functionalization.

188 Glucose is a natural ligand for sweet taste receptors (STRs) that are express

189 Expression of PD-L1, the ligand for T-cell inhibitory receptor PD-1, is one key i

190 B7-H3 (CD276), a member of the B7 family of ligands for T-cell coregulatory receptors, can be incorp

191 bond-null propofol analogue as a protecting ligand for targeted-ABPP and observed a lack of GABAA re

192 sed catalyst containing a cyclometalated NHC ligand for terminal alkenes in the presence of internal

193 ing pocket conformation using a single known ligand for that GPCR.

194 stence of a novel, presently uncharacterized ligand for the activating NK cell receptor KIR2DS2.

195 expressed within epithelia, and is the major ligand for the activatory receptor, NKG2D, both attribut

196 le bicyclic bridged ketal was developed as a ligand for the asialoglycoprotein receptor (ASGPR).

197 cultures growing on raffinose, the preferred ligand for the BlG16BP.

198 ifferentiation factor 6 (GDF6), which is the ligand for the BMP family, is recurrently amplified and

199 ructure based design into a potent nanomolar ligand for the bromodomain of human BRD9 with small resi

200 g on the bridging O-atom and on the cryptand ligand for the case of 2.

201 -cell activation, and has been proposed as a ligand for the co-receptor CD4.

202 factor (EGF)-like growth factor (HBEGF) is a ligand for the EGF receptor (EGFR), one of the most comm

203 s the 17-amino acid neuropeptide, endogenous ligand for the G-protein-coupled receptor (NOP, also kno

204 tus and anorectic actions, as the endogenous ligand for the guanylyl cyclase 2C receptor has revealed

205 Here, we identify a viral ligand for the inhibitory and activating NKR-P1 (NK1.1)

206 -classical MHC molecule (MHC-Ib) H2-M3 was a ligand for the inhibitory Ly49A.

207 that another MHC-Ib, H2-Q10, is a bona fide ligand for the inhibitory Ly49C receptor.

208 integrin-associated protein CD47, which is a ligand for the inhibitory receptor signal regulatory pro

209 The CD47 molecule is known to be a ligand for the inhibitory receptor signal regulatory pro

210 like growth factor 2 (IGF2) gene, encoding a ligand for the insulin-like growth factor 1 receptor (IG

211 ollectively, these results identify PTN as a ligand for the integrin Mac-1 on the surface of leukocyt

212 her, 10-Cl-BBQ is an effective, nontoxic AhR ligand for the intervention of immune-mediated diseases

213 gamma-d-glutamyl-meso-diaminopimelic acid, a ligand for the intracellular peptidoglycan sensor Nod1.

214 The substrate was shown to act as a ligand for the iridium catalyst in the absence of other

215 KITLG encodes a ligand for the KIT receptor.

216 igration and motility, and it also acts as a ligand for the leukocyte receptor LFA-1.

217 Here we show that alpha2delta-1 is a ligand for the Low Density Lipoprotein (LDL) Receptor-re

218 Angiopep-2 (ANG), a ligand for the low-density lipoprotein receptor-related

219 K cells acquire m157, the murine CMV-encoded ligand for the Ly49H-activating receptor, from target ce

220 ainst human B7-H6, a stress-induced cellular ligand for the natural killer (NK) cell receptor NKp30.

221 Substance P, the principal ligand for the neurokinin-1 receptor, is a potent proinf

222 B7H6 is a specific ligand for the NK cell-activating receptor NKp30.

223 idation of D2:(244)Y, which is a bicarbonate ligand for the nonheme iron, induces the propagation of

224 Mechanistically, JAGGED-1, a transmembrane ligand for the NOTCH receptor, is downregulated in the P

225 Dynorphin A (Dyn A) is an endogenous ligand for the opioid receptors with preference for the

226 Apelin-36 was discovered as the endogenous ligand for the previously orphan receptor APJ.

227 The optimized ligand for the reaction incorporates a weakly coordinati

228 2 glycan ligands and outcompetes the natural ligand for the receptor, resulting in single molecule bi

229 pharmacologically targeted by bexarotene, a ligand for the retinoid X receptor that forms heterodime

230 f a cinchona alkaloid-derived aminophosphine ligand for the silver(I) salt and the 2-bis(aryl)methylp

231 ingosine 1-phosphate (S1P) is the endogenous ligand for the sphingosine 1-phosphate receptors (S1P1-5

232 rse molecules composed of two instances of a ligand for the von Hippel-Lindau (VHL) E3 ligase.

233 ng assay, we tested a range of LRP1 and LRP2 ligands for the ability to guide growth cone navigation.

234 his dataset contains 70,219 and 9,511 unique ligands for the allosteric and competitive sets, respect

235 as prohormones for estrogen biosynthesis and ligands for the androgen receptor (AR).

236 ng step in the kynurenine pathway, producing ligands for the aryl hydrocarbon receptor (AHR).

237 as employed to construct two metallo-organic ligands for the assembly of G2 and G3 Sierpinski triangl

238 restricted to cell types that express glycan ligands for the B cell Siglecs.

239 f a number of amino acids that are essential ligands for the catalytic Mn4CaO5 metal center for water

240 nyl analogues were found to be high affinity ligands for the CB1 and CB2 cannabinoid receptors.

241 In this study we identified two novel biased ligands for the chemokine receptors CCR2 and CCR5 and ch

242 rm high-throughput screening of G-quadruplex ligands for the development of drug molecules effective

243 acids are demonstrated as effective anionic ligands for the enantioselective coupling of methylene C

244 ese compounds were shown to be high affinity ligands for the ER with nanomolar IC50 binding values.

245 g affinity or the activation by the selected ligands for the examined members of the 5-HT2 receptor c

246 e of neuroligins and cerebellins as neurexin ligands for the excitatory climbing-fiber versus paralle

247 Interest in the combinations of ligands for the extraction processes is growing, since t

248 mpounds emerge as promising safe multitarget ligands for the further development of a therapeutic app

249 apy; a class of steroids that are activating ligands for the glucocorticoid receptor (GR) transcripti

250 s farnesyl pyrophosphate (FPP) and cortisol, ligands for the glucocorticoid receptor (GR).

251 Neither was missing KIR ligands for the inhibitory KIRs (HLA-C1/C2/Bw4) in recip

252 c N-methylated hexapeptides as high affinity ligands for the integrin alphavbeta3 is based on two con

253 In the context of both HLA-C1/C2 ligands for the KIR2DS4 receptor, patient survival was f

254 art of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu2/3)

255 g-Aba-beta-Ala-NH2 (7) was linked to peptide ligands for the nociceptin receptor.

256 Bile acids are ligands for the nuclear hormone receptor farnesoid X rec

257 Bile acids are ligands for the nuclear hormone receptor, farnesoid X re

258 ion of phosphatidylcholines (PCs), which are ligands for the nuclear liver receptor homolog-1 (LRH-1)

259 aggregation (IC50) showed that two designed ligands for the open form 4c and 4d (IC50 = 6.2 nM and 2

260 f oxidized phospholipids (oxPCCD36) that are ligands for the platelet pattern recognition receptor CD

261 erous NKR-ligand interactions, physiological ligands for the prototypical NK1.1 orphan receptor remai

262 functions of these molecules, including (i) ligands for the QDs, coupled electronically or vibration

263 ory response in these cells, but the natural ligands for the receptor are not known.

264 ubated with ERBB inhibitors began to secrete ligands for the TGFbeta receptor and underwent EMT.

265 ylthiazole as potential multitarget-directed ligands for the treatment of Alzheimer's disease (AD).

266 and may present promising designed multiple ligands for the treatment of neurodegenerative disorders

267 tins are a family of growth factors that are ligands for the tyrosine kinase receptor, Tie2.

268 After screening a set of known DAT ligands for their ability to increase DAT surface expres

269 is little research into the use of DNA-based ligands for their morphological control.

270 t the in situ affinity of both pMHC and CD80 ligands for their respective receptors is modulated by t

271 ciently identifying selective small molecule ligands for therapeutically relevant RNAs.

272 clude the receptors CCR1 and CCR3; CCL7 is a ligand for these receptors.

273 KIR) family are not fully understood, as the ligands for these receptors are largely unidentified.

274 nocytes, and B cells in HCC tumors expressed ligands for these receptors.

275 Thus, we identify the long-sought foreign ligand for this key immunoregulatory NKR family and reve

276 ggest that the Tag7-Hsp70 complex is a novel ligand for this receptor.

277 tilized diphosphine, as a uniquely effective ligand for this transformation.

278 Further efficient screening of ligands for those with specific modifying effect is need

279 ment of B cells with lipopolysaccharide, the ligand for TLR4, results in SYK activation and that this

280 resistin is a clinically relevant endogenous ligand for TLR4, which promotes tumor progression via TL

281 this study were to identify NASH-associated ligands for TLR9, establish the cellular requirement for

282 he spleen in close temporal association with ligands for TLRs and/or compounds that activate NKT cell

283 osis factor-alpha (tmTNF-alpha) is the prime ligand for TNF receptor 2, which has been shown to media

284 vaccine adjuvant comprised of two synthetic ligands for Toll-like receptor 4 (TLR4) and TLR7.

285 the incorporation of Lewis acid moieties in ligands for transition metals has been studied extensive

286 wis acids, they are electron-rich and act as ligands for transition metals.

287 idine-containing peptides as multifunctional ligands for transition-metal catalysis and its applicati

288 ional theory (DFT) based screening of chiral ligands for transition-metal-catalyzed reactions with we

289 nked to pain and elevated levels of NGF (the ligand for TrkA) are associated with chronic pain.

290 We used the radiotracer [(11)C]DAA1106 (a ligand for TSPO) and positron emission tomography (PET)

291 (PPIX) is considered a conserved endogenous ligand for TSPO.

292 ng that Ntn1 is not necessarily the dominant ligand for Unc5 family members in vivo and ruling out pr

293 ed to generate novel melanocortin probes and ligands for understanding and treating obesity.

294 of chiral NHCs as stereodirecting ancillary ligands for various enantioselective transformations.

295 The major ligand for VEGFR3 is VEGFC, and there were lower levels

296 4)Cu]-LLP2A), a high affinity peptidomimetic ligand for very late Ag-4 (VLA-4; also called integrin a

297 on of adhesion molecules (such as VCAM-1 the ligand for VLA-4), and leukocyte adhesion to vascular en

298 res high substructure dissimilarity to known ligands for voltage-dependent Ca(2+) channels, selective

299 Twenty-two predicted fragment ligands, for which analogs could be acquired commerciall

300 and collagen-like peptides as physiological ligands for YKL-40.