ライフサイエンスコーパス: ligand-dependent

1 ed in urothelial carcinoma cell lines was HH ligand dependent.

2 stal residues involved in GSH binding and is ligand dependent.

3 that EGFR-induced vemurafenib resistance is ligand dependent.

4 the Shh response in Ptch1(-/-) cells remains ligand dependent.

5 strate that LRP1-initiated cell signaling is ligand-dependent.

6 and 10 rate constants, only two of which are ligand-dependent.

7 erally, our study provides insights into the ligand-dependent AA2AR activation/deactivation in additi

8 ent Structure (SiM-KARTS) to investigate the ligand-dependent accessibility of the SD sequence of an

9 tion of E2F1 expression, indicating that the ligand-dependent actions of PR on this gene may involve

10 In addition to ligand-dependent activation and concomitant tyrosine pho

11 activity during its synthesis and secretion, ligand-dependent activation at the surface, endocytic tr

12 interact with the ligand-independent and the ligand-dependent activation domains of estrogen receptor

13 This protein showed robust, ligand-dependent activation in prokaryotic and eukaryoti

14 element of the switch in this RNA, supported ligand-dependent activation of a reporter gene over a br

15 We found that MM-121 effectively blocked ligand-dependent activation of ErbB3 induced by either E

16 ffective against xenografts with evidence of ligand-dependent activation of ErbB3.

17 ective therapeutic strategy for cancers with ligand-dependent activation of ErbB3.

18 ation most effectively in cancers possessing ligand-dependent activation of ErbB3.

19 ression directed both ligand-independent and ligand-dependent activation of NFkappaB, mediated by a s

20 vely, independently of a requirement for the ligand-dependent activation of RXRalpha.

21 The latter is the case in which Slit2 ligand-dependent activation of the blood vessel endothel

22 role of Ca(2+)/CaM in the regulation of the ligand-dependent activation of the epidermal growth fact

23 ype 16 E5 oncoprotein (16E5) enhances acute, ligand-dependent activation of the epidermal growth fact

24 Ligand-dependent activation of the hedgehog (Hh) signall

25 Moreover, we showed that ligand-dependent activation of the PDGFRbeta does not tr

26 we discuss the functional evidence regarding ligand-dependent activation of TRPV1 channels in light o

27 Ligand-dependent activation, gamma-secretase-processed c

28 g the structural basis of channel gating and ligand-dependent activation.

29 To elucidate the ligand-dependent activation/deactivation mechanism of th

30 d the molecular and structural bases for its ligand-dependent activation; this was achieved by identi

31 ly of activators, functions principally as a ligand-dependent activator of promoter clearance.

32 Ligand-dependent activity has been engineered into enzym

33 DACH1 inhibited ligand-dependent activity of AR mutations identified in

34 In many diseases, expression and ligand-dependent activity of the p75(NTR) receptor can p

35 tioning both as a transcription factor and a ligand-dependent adaptor in an ubiquitin ligase complex.

36 several of these residues are important for ligand-dependent AhR activation, and their mutation resu

37 Comparative analysis of ligand-dependent alternating access in LeuT and Mhp1 lea

38 DREADD activation produced a ligand-dependent analgesia to heat in vivo and a decreas

39 -coupled) DREADD in nociceptors might enable ligand-dependent analgesia.

40 nsactivation of the AR/AR-V7 target genes in ligand dependent and independent manners respectively.

41 gnaling in tissue-resident macrophages, both ligand dependent and independent, limited HIV-1 replicat

42 n of IFN-gamma and IL-12 family cytokines is ligand dependent and is observed in both mouse and human

43 ing (NB) domains that regulate both effector ligand-dependent and -independent cell death signaling a

44 We observe both ligand-dependent and -independent kinetic phases which,

45 ctive oxygen species (ROS) and involves both ligand-dependent and -independent mechanisms, but the pr

46 Both ligand-dependent and -independent pathways converge on p

47 Ligand-dependent and ligand-independent activation of th

48 Both ligand-dependent and ligand-independent activities are e

49 owth factor receptor (EGFR) and enhances its ligand-dependent and ligand-independent activity.

50 androgen receptor and strongly enhance both ligand-dependent and ligand-independent androgen-recepto

51 ancy, leading ultimately to a suppression of ligand-dependent and ligand-independent AR residence on

52 ment of a variety of organ systems, and both ligand-dependent and ligand-independent Hh pathway activ

53 pshift was associated with increases in both ligand-dependent and ligand-independent PR phosphorylati

54 r endocytosis and lysosomal degradation in a ligand-dependent and receptor kinase activity-dependent

55 ional changes in the clamp region of RyR are ligand-dependent and suggest the existence of multiple l

56 Sumoylation of TRbeta was ligand-dependent, and sumoylation of TRalpha was ligand-

57 ematically investigated events downstream of ligand-dependent AR activation in a Drosophila model of

58 Although previous studies have focused on ligand-dependent AR signaling, in this study we explore

59 of FoxA1, a transcription factor involved in ligand-dependent AR targeting.

60 A key step in JA signaling is ligand-dependent assembly of a coreceptor complex consis

61 The aryl hydrocarbon receptor (AhR) is a ligand-dependent, basic helix-loop-helix Per-Arnt-Sim (P

62 a subtypes, ligand-independent ('tonic') and ligand-dependent BCR signaling have been characterized,

63 ein pathways and beta-arrestin pathways; the ligand-dependent bifurcation of such signaling is referr

64 ide the first direct characterization of the ligand-dependent binding of the retinoic X receptor to t

65 These data uncover a ligand-dependent, but gamma-secretase-independent, non-c

66 or LRP6 is overexpressed, signaling remains ligand-dependent, but the requirement for both receptors

67 we tested the hypothesis that it influences ligand-dependent Ca(2+) release.

68 d be explored to treat patients harboring HH ligand-dependent cancers.

69 stant to ectodomain shedding, inhibited RAGE ligand dependent cell signaling, actin cytoskeleton reor

70 90, chaperone ER-alpha36 activity, stimulate ligand-dependent cell growth, and render tamoxifen resis

71 We report here that neuritogenesis-promoting ligand-dependent cell surface clustering of CHL1 induces

72 tablish a threshold that was correlated with ligand-dependent changes in cell proliferation.

73 The results showed heme ligand-dependent changes in the protein-electrode intera

74 scale faster than the greatest difference in ligand-dependent chemical shift (i.e. >100 Hz).

75 The ligand-dependent competing actions of nuclear receptor (

76 es, evaluate protein structure, and identify ligand dependent conformational changes in proteins are

77 A ligand-dependent conformational change is thought to reg

78 in nanodiscs undergoes functionally relevant ligand-dependent conformational changes and that previou

79 The observed ligand-dependent conformational changes in KirBac1.1 pro

80 ignals provided evidence of redox-state- and ligand-dependent conformational changes localized near t

81 ) undergoes modest redox-state-dependent and ligand-dependent conformational changes.

82 ues and x-ray crystallography to examine the ligand-dependent conformational dynamics of CYP119.

83 tudy the structural features involved in the ligand-dependent conformational heterogeneity of GPCRs b

84 ables transcription intermediates to undergo ligand-dependent conformational refolding.

85 l pH levels, and they fail to undergo pH- or ligand-dependent conformational switching.

86 Ligand-dependent control of gene expression is essential

87 sensor protein RsbR binds haem and exhibits ligand-dependent control of the stressosome complex acti

88 etic pathway in a single step and showed the ligand-dependent coordinated expression of all five gene

89 idely expressed transcriptional coregulator, ligand-dependent corepressor (LCoR), initially character

90 In line with this, progressive decrease of ligand-dependent corepressor expression was observed in

91 ession is controlled with near-IR light in a ligand-dependent CreER(T)/LoxP-reporter cell line derive

92 Binding of beta-arrestin1 to IGF-1R leads to ligand-dependent degradation of the receptor and generat

93 This arrangement suggests a potential ligand-dependent dimerization mechanism for TCR signalin

94 Upon the ligand-dependent dimerization of the epidermal growth fa

95 ty of activation mechanisms, often involving ligand-dependent dimerization or conformational changes.

96 urine AhR and ARNT proteins was designed and ligand-dependent DNA binding ability of the AhR:ARNT het

97 cases such as docking to homology models and ligand dependent domain rearrangements.

98 conditioning and allogeneic BMT, induce PD-1 ligand-dependent donor nTreg proliferation, and maintain

99 d with lowered ligand sensitivity and slowed ligand-dependent down-regulation.

100 urface proteins, we observed significant PDZ ligand-dependent EAAT2b surface expression in cultured a

101 talloprotease ADAM10/Kuzbanian catalyzes the ligand-dependent ectodomain shedding of Notch receptors

102 ing a new single-vector strategy that allows ligand-dependent, efficient removal of a gene of interes

103 by wound-derived signals such as ATP, direct ligand-dependent EGFR activation primarily involves NOX2

104 ading cells with a Ca(2+) chelator inhibited ligand-dependent EGFR auto(trans)phosphorylation.

105 gistic and antagonistic interactions between ligand-dependent EGFRwt and EGFRvIII signaling.

106 for FLS2 and reveal a defined framework for ligand-dependent endocytosis of this receptor.

107 as inhibition of degranulation was OX40/OX40 ligand dependent, enhancement of IL-6 was due to TGF-bet

108 Condensins positively regulate ligand-dependent enhancer activation at least in part by

109 nexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicki

110 a (ERalpha) to define two distinct phases of ligand-dependent enhancer formation.

111 ne kinase, PDGFRbeta, which facilitates PDGF ligand-dependent, ephrin ligand-independent activation o

112 EpoR cytoplasmic tyrosines are important for ligand-dependent EpoR internalization.

113 region contains a previously uncharacterized ligand-dependent ERalpha binding function, indicating ho

114 his phenotype, as well as loss of the strong ligand-dependent estrogen receptor (ER)alpha-Mediator in

115 Sites of ligand-dependent exchange differences were localized by

116 ystem was devised that enables quantitative, ligand-dependent exponential amplification for various l

117 D and L reaction systems undergo isothermal, ligand-dependent exponential amplification in the same m

118 This interaction required ligand-dependent exposure of a TCF binding region that m

119 reduces cancer cell proliferation in a Notch-ligand dependent fashion.

120 teract with the glucocorticoid receptor in a ligand-dependent fashion and globally alter the transcri

121 to modify the output of other receptors in a ligand-dependent fashion may be a general principle for

122 ptor and regulatory domains communicate in a ligand-dependent fashion to regulate mRNA expression.

123 y interact with the APC/C(Cdh1) complex in a ligand-dependent fashion without being targeted for prot

124 ion allows the protein to interconvert, in a ligand-dependent fashion, between two mutually exclusive

125 OSTbeta organic solute transporter loci in a ligand-dependent fashion.

126 pump (BSEP)] promoter reporter activity in a ligand-dependent fashion.

127 all, these data reveal an essential role for ligand-dependent feedback inhibition of vertebrate HH si

128 ches of the same class that exhibit strictly ligand-dependent folding.

129 The present data suggest that ligand-dependent formation of HMGA1-Ubc9-PPARgamma compl

130 ational changes compatible with thermal- and ligand-dependent gating.

131 Here, we show that ligand-dependent GCC signaling through cGMP induces func

132 ptors (NRs), which play an important role in ligand-dependent gene expression and human health.

133 mponent of the SMRT complexes, important for ligand-dependent gene regulations by ERalpha and a suppr

134 findings indicate that nuclear receptor-like ligand-dependent gene regulatory mechanisms emerged earl

135 Flt3 ligand-dependent generation of CD8alpha(+) cDCs in lymph

136 This occurred via a ligand-dependent, genotype-independent mechanism accordi

137 However, complete details of ligand-dependent GPCR activation/deactivation are diffic

138 revealing distinct structural mechanisms for ligand-dependent GPCR function.

139 rodimeric nuclear receptors can also mediate ligand-dependent HBV transcription and replication when

140 luable probe for investigating and targeting ligand-dependent hedgehog pathway activation in cancer a

141 Subsequently, we monitored the ligand-dependent HER profiles based on receptor expressi

142 In particular, the existence of autocrine, ligand-dependent Hh signaling in SCLC has been disputed.

143 Taken together, our data show that ligand-dependent homotypic interactions in D5 and D7 are

144 pharmacological characterization indicated a ligand-dependent increase in intracellular calcium in 13

145 The ligand-dependent increase in keratinocyte adhesion and d

146 athway in isolated mouse VSMCs revealed CD36 ligand-dependent induction of Fyn phosphorylation, with

147 ependent repression of GR expression, or the ligand-dependent induction of GR phosphorylation on Ser-

148 that p75NTR in glia and in pericytes mediate ligand-dependent induction of inflammatory cytokines, di

149 ry early in glia and in pericytes to mediate ligand-dependent induction of inflammatory cytokines, di

150 em to exert important roles for the observed ligand-dependent induction of target coding genes, incre

151 s suggests that NgR1 and PirB participate in ligand-dependent inhibition of synaptic plasticity.

152 This dynamic and ligand-dependent interaction with chromatin is likely sh

153 tor function of the Mediator involves direct ligand-dependent interactions of the MED1 subunit, throu

154 the binding site residues gain different and ligand-dependent interactions that could not be predicte

155 us convergent regulatory mechanisms of these ligand-dependent ion channels.

156 were more sensitive to Ca-dependent and Fas ligand-dependent killing by cytotoxic T lymphocytes.

157 An initial fast ligand-dependent kinetic process appears to be consisten

158 n protein X-ray crystallographic structures, ligand-dependent LBD stabilization assays, and cell-base

159 tering enhances valency and further promotes ligand-dependent LFA-1 activation.

160 udes a dynamic alpha9 helix that undergoes a ligand-dependent localization to complete the active sit

161 anscriptionally by the androgen pathway in a ligand-dependent manner and is further enhanced by the h

162 phrin receptor EphB2 can form a complex in a ligand-dependent manner and that Netrin-ephrin synergist

163 canonical DRE-dependent transactivation in a ligand-dependent manner and, in doing so, prove the conc

164 omers and if these species interconvert in a ligand-dependent manner are among the most contentious c

165 receptor 2 (DR5) forms receptor dimers in a ligand-dependent manner at endogenous receptor levels, a

166 r RNA enzymes have been made to operate in a ligand-dependent manner by combining a catalytic domain

167 ter assay findings suggest that PR acts in a ligand-dependent manner through binding to two progester

168 d that STAT5 is recruited to the IL-25R in a ligand-dependent manner through unique tyrosine residues

169 e ANTH and ENTH domains bind each other in a ligand-dependent manner to provide critical anchoring of

170 we demonstrate that G-proteins modulate in a ligand-dependent manner two fundamental cell-polarity be

171 egatively regulates IL-6 expression in a BMP ligand-dependent manner via the p38 MAPK and Erk1/2 path

172 corepressor complexes, which associate in a ligand-dependent manner with FXR, and increased FXR bind

173 D3) cells, Dragon generated BMP signals in a ligand-dependent manner, and BMP4 is the predominant end

174 ansmits this conformational plasticity, in a ligand-dependent manner, to a phenylalanine residue (Phe

175 Importantly, ARGLU1 is recruited, in a ligand-dependent manner, to endogenous estrogen receptor

176 nterface for binding signaling partners in a ligand-dependent manner.

177 d vaginal epithelial cell proliferation in a ligand-dependent manner.

178 lls and induced their apoptosis in a Fas/Fas ligand-dependent manner.

179 olonocytes blocks TNF-induced apoptosis in a ligand-dependent manner.

180 ) and rexinoid receptor (RXRs) subtypes in a ligand-dependent manner.

181 ation through phosphorylation of AtRGS1 in a ligand-dependent manner.

182 FAM150A stimulates LTK phosphorylation in a ligand-dependent manner.

183 6 can also induce neural crest markers via a ligand-dependent mechanism involving FGF8 and Wnt8.

184 In cancer, ErbB3 activation is driven by a ligand-dependent mechanism through the formation of hete

185 th via activation of Caspase-8 through a Fas ligand-dependent mechanism.

186 nergic P2Y(2) receptor stimulation, and both ligand-dependent mechanisms as well as ligand-independen

187 n cell migration assays indicated that Gal-1 ligand-dependent melanoma cell migration was severely in

188 Ligand-dependent Mer or Axl activation stimulated MAPK,

189 ompeted with HGF for MET binding, inhibiting ligand-dependent MET activity, downregulated cell surfac

190 l region of the receptor renders AR prone to ligand-dependent misfolding and formation of oligomers a

191 ependent negative feedback potently suppress ligand-dependent mitogenic signaling and Ras function.

192 lts provide strong support for an autocrine, ligand-dependent model of Hh signaling in SCLC pathogene

193 nic cation transporter (rOct1), voltage- and ligand-dependent movements of fluorescence-labeled cyste

194 ion that can be attributed to an increase in ligand-dependent Notch (N) signalling.

195 membranes is an important element in tuning ligand-dependent Notch signalling in different physiolog

196 Induction of autophagy required ligand-dependent, Notch intracellular domain (NIC) activ

197 Estrogen receptor alpha (ERalpha) is a ligand-dependent nuclear receptor that is important in b

198 A ligand-dependent nuclear transcription factor, ERalpha h

199 Using modified ERalpha to assay ligand-dependent nuclear translocation, we observed D3-d

200 We found that NAIP proteins control ligand-dependent oligomerization of NLRC4 and that the N

201 t activation of iNKT cells by viruses or TLR ligands, dependent on self-antigen recognition and/or di

202 nique allosteric mechanism for inhibition of ligand-dependent or ligand-independent ErbB3-driven canc

203 ecules are responsible for regulating normal ligand-dependent or oncogenic RTK activation via a "zipp

204 The long distance, ligand-dependent ordering of residues reveals new elemen

205 receptor activator of nuclear factor kappaB ligand-dependent osteoclast differentiation and MMP-9 se

206 s are not required for ligand-independent or ligand-dependent p75(NTR) activation in a growth cone re

207 ants) and therefore are completely devoid of ligand-dependent pathway activation.

208 or both perforin/granzyme as well as Fas/Fas ligand-dependent pathways of killing by NK cells.

209 receptor (AhR) is a conserved, environmental ligand-dependent, per ARNT-sim (PAS) domain containing b

210 ransfected with the human EGFR decreased its ligand-dependent phosphorylation.

211 ecognized conformational switch accompanying ligand-dependent PPARdelta transcriptional regulation.

212 In adipocytes, ligand-dependent PPARgamma activation is associated with

213 -independent activity, whereas AF-2 mediates ligand-dependent PR activation.

214 Both constitutive and ligand-dependent pre-BCR activation modes have been desc

215 By imaging ligand-dependent preQ1 riboswitch folding from multiple

216 Ligand-dependent proteolysis at the S2 site removes the

217 nished transcriptional function and exhibits ligand-dependent proteotoxicity, features that have both

218 on about the molecular mechanisms underlying ligand-dependent receptor activation is beginning to eme

219 Fuc-TVII(-/-) mice, indicating that selectin ligand-dependent recruitment of monocytes is required fo

220 sence of Slitrk5, TrkB has a reduced rate of ligand-dependent recycling and altered responsiveness to

221 K2 activities, indicating an endogenous, non-ligand-dependent regulation of PXR and CYP3A4, possibly

222 Ligand-dependent regulation of the channel activity is a

223 ctural elements that contribute to efficient ligand-dependent regulatory activity in a co-transcripti

224 n-binding hemerythrin domain that acted as a ligand-dependent regulatory switch mediating FBXL5's dif

225 These studies identify ligand-dependent removal of activated alpha2 receptors f

226 ect glucocorticoid receptor (GR) expression, ligand-dependent repression of GR expression, or the lig

227 ual role of ligand-independent activator and ligand-dependent repressor of E-cadherin in breast cance

228 Removing FL or FGF2 from ligand-dependent resistant cultures transiently restored

229 The principle of ligand-dependent RNA catalysis has now been extended to

230 endent and suggest the existence of multiple ligand dependent RyR activation mechanisms associated wi

231 BM progenitors, supporting a requirement for ligand-dependent selection, as is the case for normal B1

232 Aptazymes are small, ligand-dependent self-cleaving ribozymes that function i

233 from L-ribonucleotides, was shown to undergo ligand-dependent, self-sustained replication with expone

234 ions of which depended on ligand, whereas no ligand-dependent shifts were observed, consistent with t

235 RIP6-NHERF2 ternary complex provides a novel ligand-dependent signal amplification mechanism that is

236 logically important pleiotropic coupling and ligand-dependent signal bias.

237 f of ERK-dependent feedback, reactivation of ligand-dependent signal transduction, increased Ras-GTP,

238 l for IRAK4 autophosphorylation in vitro and ligand-dependent signaling in cells.

239 harmacologically characterized and exhibited ligand-dependent signaling, internalization, and wild-ty

240 de RNAi screen to identify genes involved in ligand-dependent signaling, we unexpectedly identified t

241 erexpression and amplification show enhanced ligand-dependent signaling, with increased activation of

242 s define rules guiding how NRs integrate two ligand-dependent signalling pathways into RXR heterodime

243 yet the molecular mechanisms responsible for ligand-dependent signalling responses remain poorly unde

244 ngs provide a model system for investigating ligand-dependent signalling within stressosome complexes

245 ght impact on our understanding of basal and ligand-dependent signalling.

246 id X receptor (RXR), allowing integration of ligand-dependent signals across the dimer interface via

247 Thus, ligand-dependent simultaneous activation of multiple pat

248 in vitro and in vivo work that demonstrated ligand-dependent species differences in AHR1 affinity.

249 This ligand-dependent stabilization of rate-defining conforma

250 duction of endogenous miR-9 expression, upon ligand-dependent stimulation of PDGFRbeta signaling, pro

251 Ligand-dependent SUMOylation of farnesoid X receptor (FX

252 Ligand-dependent SUMOylation of liver X receptors (LXRs)

253 ese results indicate that IL-7 induces CXCR3 ligand-dependent T cell antitumor reactivity in lung can

254 We devised a chemical strategy that promotes ligand-dependent target protein degradation using as an

255 investigating this aspect of RNA folding as ligand-dependent termination is obligatorily co-transcri

256 ere PKA-mediated Ser-2152 phosphorylation is ligand-dependent, the P2204L mutant is readily accessibl

257 s, CORM-2 inhibited endogenous and exogenous ligand-dependent TLR4 activation, which indicates that C

258 s, suggesting that oxidative stress enhanced ligand-dependent TNFR signaling.

259 reveal a linkage between eRNA synthesis and ligand-dependent TOP1-mediated nicking-a strategy exerti

260 n in the androgen receptor, which results in ligand-dependent toxicity.

261 ERalpha has a ligand-dependent transactivation function in the ligand

262 reveals a novel function for Crb in limiting ligand-dependent transactivation of the N receptor at th

263 s functional inactivation and attenuation of ligand-dependent transactivation.

264 Expression of Sumo1 markedly inhibited the ligand-dependent, transactivation of BSEP and SHP promot

265 Ligand-dependent transcription by the nuclear receptor g

266 Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor containing two tra

267 The estrogen receptor (ER) is a ligand-dependent transcription factor containing two tra

268 iated by the glucocorticoid receptor (GR), a ligand-dependent transcription factor of the nuclear rec

269 (GRIP1), function as coactivators for GR, a ligand-dependent transcription factor of the nuclear rec

270 or-activated receptor gamma (PPARgamma) is a ligand-dependent transcription factor that acts as a pri

271 The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that binds to xeno

272 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that can be activa

273 Glucocorticoid receptor (GR) is a ligand-dependent transcription factor that can promote a

274 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that regulates exp

275 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor whose activity is

276 GC signal through the GC receptor (GR), a ligand-dependent transcription factor whose structure, D

277 ngly, the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor with an emerging r

278 Pregnane X receptor (PXR) is a ligand-dependent transcription factor, regulating gene e

279 antitative assays for the activation of this ligand-dependent transcription factor.

280 At the molecular level, ERs function as ligand-dependent transcription factors and activate targ

281 R) belongs to the nuclear receptor family of ligand-dependent transcription factors and mediates the

282 ligands may switch DNA motifs recognized by ligand-dependent transcription factors in vivo.

283 proliferator-activated receptors (PPARs) are ligand-dependent transcription factors regulating lipid

284 Estrogen receptors (ERs) alpha and beta are ligand-dependent transcription factors that are expresse

285 Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate most

286 such as the glucocorticoid receptor (GR) are ligand-dependent transcription factors that mediate tran

287 Steroid hormone receptors are ligand-dependent transcription factors that require the

288 s a member of the nuclear receptor family of ligand-dependent transcription factors, the main action

289 ember of the nuclear receptor superfamily of ligand-dependent transcription factors.

290 t for the design of allosteric modulators of ligand-dependent transcription factors.

291 gamma, thereby solidifying their function as ligand-dependent transcription factors.

292 boswitches have been constructed to regulate ligand-dependent transcription termination in Escherichi

293 tutes a repressive barrier to the process of ligand-dependent transcriptional activity of nuclear rec

294 include castration modalities that suppress ligand-dependent transcriptional activity of the androge

295 corepressor recruitment is a key feature of ligand-dependent transcriptional repression by Ers, and

296 ion is emerging as an important regulator of ligand-dependent transmembrane signaling, but precisely

297 GFR ligands and has potential for use in EGF ligand-dependent tumours.

298 ine-phosphorylated GIV in vitro and inhibits ligand-dependent tyrosine phosphorylation of GIV downstr

299 y a fibroblast-specific promoter, leading to ligand-dependent up-regulation of TGFbeta signaling, and

300 Ligand-dependent Y504 phosphorylation modulates the EphB