ライフサイエンスコーパス: ligand-gated channel

1 recognition by insect ORs, a novel class of ligand-gated channel.

2 mechanisms for the superfamily of pentameric ligand-gated channels.

3 channels, but not sodium (Na(+)) channels or ligand-gated channels.

4 , a common theme for activating mutations in ligand-gated channels.

5 data of ethanol action on a wide variety of ligand-gated channels.

6 of the OFF bipolar that arises directly from ligand-gated channels.

7 tivity modulators or downstream effectors of ligand-gated channels.

8 mediates rapid excitatory responses through ligand-gated channels (5-HT3 receptors).

9 ction of a variety of ion channels including ligand-gated channels activated by ATP, acetylcholine, G

10 The P2X receptors (P2XRs) are a family of ligand-gated channels activated by extracellular ATP thr

11 re are three forms of IP3R, all of which are ligand-gated channels activated by the second messenger

12 This cross-regulation of ligand-gated channel activity by protein kinases may pla

13 allostery that are shared with conventional ligand-gated channels and (ii) the R domain modulates CF

14 fects that have been observed for pentameric ligand-gated channels and may represent a previously unk

15 erpretation of protein allostery for general ligand-gated channels and receptors.

16 Although both voltage- and ligand-gated channels are being extensively studied, the

17 Different classes of ligand-gated channels associate with distinct sets of in

18 The role of desensitization of ligand-gated channels at fast chemical synapses has been

19 TR gating is distinct from that of a typical ligand-gated channel because its ligand (ATP) is usually

20 Unlike conventional ligand-gated channels, CFTR is an ATPase for which ligan

21 c Ca(2+)-gated K(+) channel that, like other ligand-gated channels, converts the chemical energy of l

22 c properties that are common to conventional ligand-gated channels (e.g. unliganded openings and cons

23 For ligand-gated channels each state can represent a differe

24 hosphorylated CFTR behaves as a conventional ligand-gated channel employing cytoplasmic ATP as a read

25 forms are a family of ubiquitously expressed ligand-gated channels encoded by three individual genes.

26 +]i increases result from Ca2+ entry through ligand-gated channels, entry through voltage-gated chann

27 to menthol or cold, TRPM8 behaves like many ligand-gated channels, exhibiting rapid activation follo

28 ated ion channels (5-HT3) are members of the ligand-gated channel family, which includes channels tha

29 zation remain unavailable for the pentameric ligand-gated channel family.

30 show that the binding domains of tetrameric ligand-gated channels form either a 4-fold symmetric gat

31 GABAARs are heteropentameric ligand-gated channels formed by the combination of 19 po

32 butyric acid) exerts its effects through two ligand-gated channels, GABA(A) and GABA(C) receptors, an

33 Despite their widespread nature, no ligand-gated channels have yet been found within the out

34 RPV1 or vanilloid receptor is a nonselective ligand-gated channel highly expressed in primary sensory

35 may prove useful for investigating models of ligand-gated channels in biological membranes.

36 Q) due to each of the different voltage- and ligand-gated channels in the cells in the presence of fa

37 Ligand-gated channels, in which a substrate transport pa

38 cognized that this small molecule influences ligand-gated channels, including the GABAA receptor and

39 an affect neuronal excitability by acting on ligand-gated channels, including those gated by glutamat

40 Activation of ligand-gated channels is initiated by the binding of sma

41 For ligand-gated channels, it is challenging to separate lig

42 This increases Ca2+ binding to ligand-gated channels known as ryanodine receptors (RyR2

43 ty of crystallographic information for these ligand-gated channels, little is known about the structu

44 Ligand-gated channels mediate synaptic transmission thro

45 GABAA receptors are pentameric ligand-gated channels mediating inhibitory neurotransmis

46 te Ca(2+) entry through voltage-dependent or ligand-gated channels of the plasma membrane.

47 c [Ca2+]i can result from Ca2+ entry through ligand-gated channels or voltage-gated Ca2+ channels, or

48 c activation opening voltage gated channels, ligand gated channels, or mobilizing Ca(2+) release from

49 P receptors can modulate voltage- as well as ligand-gated channels permeable to calcium and may play

50 In ligand-gated channels, pore opening is conferred through

51 ctance expands the complex repertoire of the ligand-gated channel properties associated with EAAT4.

52 binding of neurotransmitters in voltage- and ligand-gated channels, respectively.

53 y inference, other members of the homologous ligand-gated channel superfamily, which include the iono

54 Vanilloid receptor subtype 1 (VR1) is a ligand-gated channel that can be activated by capsaicin

55 oned vanilloid receptor subtype 1 (VR1) is a ligand-gated channel that is activated by capsaicin, pro

56 2+ release channel (ryanodine receptor) is a ligand-gated channel that is activated by micromolar cyt

57 f ADPR or AMPCPR, identify TRPM2 as a simple ligand-gated channel that obeys an equilibrium gating me

58 IP3 receptors--ligand-gated channels that release Ca2+ from intracellul

59 loop receptors (CLRs) are commonly known as ligand-gated channels that transiently open upon binding

60 Akin to ligand-gated channels, the dilated state of the midplane

61 esumably occupy overlapping binding sites on ligand-gated channels, these interactions cannot be iden

62 dulate T currents but not other voltage- and ligand-gated channels thought to mediate pain sensitivit

63 ge-gated Ca(2+) channels, various Ca(2+)- or ligand-gated channels, Trp family channels, and even the

64 tamate receptors are postsynaptic tetrameric ligand-gated channels whose activity mediates fast excit

65 alized by considering CFTR as a hydrolyzable-ligand-gated channel with cytoplasmic ATP as ligand.

66 TR gating that combines the allosterism of a ligand-gated channel with its unique enzymatic activity.

67 2+) permeable isoform, is by far the fastest ligand-gated channel with the channel-opening and -closi