ライフサイエンスコーパス: ligature

1 one of the first molars chosen to receive a ligature.

2 l as proteolytic enzyme activity, induced by ligature.

3 , and at the end of 1 hour of treatment with ligature.

4 ter left anterior descending coronary artery ligature.

5 wns was visualized by a metallic interdental ligature.

6 t the proximal and distal sides of an axonal ligature.

7 78 +/- 7.27, respectively) in the sides with ligature.

8 AF exhibited higher ABL in the sides without ligature.

9 /-)) and challenged them with acute coronary ligature.

10 PD was induced by a ligature.

11 ntitis model induced by P. gingivalis-soaked ligatures.

12 mandibular and second maxillary molars using ligatures.

13 peralgesic response in animals not receiving ligatures.

14 ion of periodontitis in rats by placement of ligatures.

15 animals per group): 1) control rats (without ligature); 2) rats with ligature + placebo (saline; oral

16 ; 2) group L: periodontal disease induced by ligature; 3) group G-Pg: oral gavage with Porphyromonas

17 umulation of AT(1) receptors proximal to the ligature, a demonstration of anterograde receptor transp

18 Distance from the ligature, a variable common to all arterial ligation exp

19 After femoral neck ligature, ADC increased a mean of 27% after 6 hours and

20 Negative controls included ligature alone (14 animals) or ligature + P. gingivalis

21 Ligature alone caused a mean bone loss of 1.01 +/- 0.06

22 SIM/SIM-mPEG; 4) 1.5 mg SIM/SIM-mPEG; or 5) ligature alone.

23 The Lig + CsA group received silk ligature and CsA treatment.

24 or MRE (10, 30, and 90 mg/kg) 1 hour before ligature and daily until day 11.

25 The ligature and injection of heat-killed Pg models were the

26 (STZ+Mel, n = 8); 4) ligature (L, n = 6); 5) ligature and melatonin (L+Mel, n = 8); 6) STZ and ligatu

27 rmore, polymicrobial sepsis induced by cecal ligature and puncture resulted in early death of these a

28 Coecal ligature and puncture was performed to obtain nonlethal

29 yte and monocyte signals at 24 h post-coecal ligature and puncture, a response mediated by TNFalpha.

30 ctomy, one first mandibular molar received a ligature and the contralateral tooth was not ligated.

31 rimental periodontitis in the rat by placing ligatures and assessed the impact of AN0128 and positive

32 Wire ligatures and cotton pellets were left in place for 2 mo

33 STZ and ligature (STZ+L, n = 8); and 7) STZ, ligature, and melatonin (STZ+L+Mel, n = 8).

34 pha exacerbates the hyperalgesic response by ligatured animals, and induces a hyperalgesic response i

35 aration (carrier) only, and two animals with ligature application alone served as negative controls.

36 d by placing a sterilized nylon (000) thread ligature around the cervix of the second left upper mola

37 scaling procedures and placing braided silk ligature around the implants.

38 n of periodontitis via the installation of a ligature around the mandibular left first molar.

39 PD was induced by cotton ligature around the maxillary left first molars (PDSG an

40 , GIOP + EP, and ATV were submitted to EP by ligature around the maxillary left second molars for 11

41 schemia was investigated with placement of a ligature around the neck of a femur (n = 7); the ADC of

42 Periodontitis was induced by ligature around the same molar in seven rats.

43 val inflammation was then initiated by tying ligatures around 12 study teeth per dog and by placing t

44 iodontal disease was induced by placing silk ligatures around both maxillary and mandibular teeth.

45 ls of groups EP and EP-HN019 received cotton ligatures around mandibular first molars (MFMs).

46 tiated in 18 New Zealand White rabbits using ligatures around mandibular second premolars, followed b

47 sing an isolated frog heart preparation with ligatures around the atria, Luigi Luciani, an Italian ph

48 PED was induced by placing ligatures around the cervix of the maxillary second mola

49 was induced by wrapping P. gingivalis-soaked ligatures around the left maxillary second molar and cha

50 ntal disease was induced by placing 2.0 silk ligatures around the mandibular first molar and premolar

51 PED was simulated by placing ligatures around the neck of teeth for 5 weeks.

52 ic BOO was induced by placing lumen reducing ligatures around the proximal urethra.

53 One-half of the animals received silk ligatures around their mandibular premolars followed by

54 Inflammatory responses to subgingival ligatures, assessed by changes in peripheral blood diffe

55 s monkeys (Macaca mulatta) by tying 2.0 silk ligatures at the gingival margins of maxillary premolar/

56 ver, in gingival tissue sampled 3 days after ligature attachment, fluoxetine administration reduced I

57 inucleated TRAP+ cells in mice that received ligature attachment.

58 sponse to periodontitis-inducing subgingival ligatures compared with wild-types.

59 t affecting MMP-9 mRNA expression induced by ligature, compared to the ligature + placebo group (P <0

60 mG); maxillary right molars were used as non-ligature controls.

61 periodontitis and placebo treatment; and 3) ligature + doxycycline group: ligature-induced periodont

62 This non-human primate study indicates that ligature-enhanced plaque accumulation is a precursor of

63 left maxillary second molar and changing the ligatures every other day.

64 cebo (saline; oral gavage); and 3) rats with ligature + fluoxetine (20 mg/kg/day in saline; oral gava

65 IR = ischemia-reperfusion) and releasing the ligature for 30 min.

66 ary artery for 90 min and then releasing the ligature for 30 min.

67 an, after which periodontitis was induced by ligature for 4 weeks.

68 nduced by either Porphyromonas gingivalis or ligature, gamma-proteobacteria accumulate and stimulate

69 and and osteoprotegerin) was observed in the ligature group on day 7.

70 e-induced periodontitis and no treatment; 2) ligature group: ligature-induced periodontitis and place

71 was induced in groups PERIO and CAF+PERIO by ligatures in the upper second molar.

72 The 11 days of ligature induced bone resorption, low levels of BALP, le

73 Attachment of ligature induced significantly elevated tumor necrosis f

74 Ligature-induced alveolar bone loss was diminished in ch

75 ation of anti-DC-STAMP-mAb downregulated the ligature-induced alveolar bone loss.

76 ent and radiographic alveolar bone loss in a ligature-induced beagle dog model.

77 ts of caffeine and/or estrogen deficiency on ligature-induced bone loss (BL), trabecular bone area (T

78 on controls (n = 10); (2) sham-operation and ligature-induced bone loss (n = 10); (3) orchiectomy wit

79 of the TRPV1 agonist, capsaicin, suppressed ligature-induced bone loss in mice with fewer tartrate-r

80 and subphysiologic levels of testosterone on ligature-induced bone loss in rats.

81 esented increased gingival area accompanying ligature-induced bone loss.

82 subphysiologic levels significantly increase ligature-induced bone loss.

83 titis at baseline and during the 6 months of ligature-induced disease.

84 th extraction of healthy teeth or teeth with ligature-induced EP and ZA-treated animals with extracti

85 periodontal attachment loss associated with ligature-induced experimental periodontal disease in rat

86 ur groups: 1) no periodontitis induction; 2) ligature-induced experimental periodontitis (group PR);

87 female Sprague Dawley rats were subjected to ligature-induced experimental periodontitis between maxi

88 on periodontal inflammation and bone loss in ligature-induced experimental periodontitis in vivo Puri

89 iched diet to ABL was not found in rats with ligature-induced experimental periodontitis, these findi

90 ially prevented the periodontal breakdown in ligature-induced experimental periodontitis.

91 The effects of CsA on ligature-induced expressions of gelatinases and EMMPRIN

92 s, CR resulted in a significant reduction in ligature-induced GI (P <0.0001), BOP (P <0.0015), PD (P

93 etate (SBHA) with 0.3% (w/v) NaOH (SBHAN) on ligature-induced gingival inflammation in the beagle dog

94 Using a ligature-induced model in type-2 Zucker diabetic fatty (

95 ition on alveolar bone loss, an experimental ligature-induced model of periodontitis was used.

96 In a ligature-induced model of periodontitis, we demonstrate

97 These findings were confirmed in an in vivo ligature-induced mouse periodontitis model in which adop

98 show evidence that the P. gingivalis-soaked ligature-induced murine model mounts an adequate inflamm

99 iodontal pathogens in plaque associated with ligature-induced peri-implantitis and ligature-induced p

100 In vivo studies revealed that ligature-induced periodontal bone loss is significantly

101 The inhibitory effects of CsA on the ligature-induced periodontal breakdown was examined with

102 d) were divided into two groups, with either ligature-induced periodontal disease (LPD) or control co

103 achment loss and radiographic bone loss in a ligature-induced periodontal disease beagle dog model.

104 (OM) on the periodontal tissues of rats with ligature-induced periodontal disease.

105 t molars of rats sacrificed at 15 days after ligature-induced periodontal disease.

106 mmatory tissue destruction in a rat model of ligature-induced periodontal disease.

107 local treatment of NHPs with Cp40 inhibited ligature-induced periodontal inflammation and bone loss,

108 ntibody (mAb) was tested in a mouse model of ligature-induced periodontitis ( n = 6-7/group) where Pa

109 uence of probiotic (PROB) supplementation on ligature-induced periodontitis (LIP) and intestinal morp

110 domly to the following: 1) control group: no ligature-induced periodontitis and no treatment; 2) liga

111 ontitis and no treatment; 2) ligature group: ligature-induced periodontitis and placebo treatment; an

112 atment; and 3) ligature + doxycycline group: ligature-induced periodontitis and SDD treatment.

113 fects of probiotic therapy (PT) in rats with ligature-induced periodontitis associated with restraint

114 nologic characteristics of a baboon model of ligature-induced periodontitis during pregnancy.

115 ected to experimental gingivitis followed by ligature-induced periodontitis in a split-mouth design.

116 Our findings suggest that ligature-induced periodontitis in animals with diabetes

117 formulation (fabricated with human CCL22) in ligature-induced periodontitis in beagle dogs leads to r

118 duction, progression, and recovery phases of ligature-induced periodontitis in rats, with the results

119 ase of pericytes and liver disease caused by ligature-induced periodontitis in rats.

120 te the effects of electroacupuncture (EA) on ligature-induced periodontitis in rats.

121 s an adjuvant to the mechanical treatment of ligature-induced periodontitis in rats.

122 he effects of local administration of TIL on ligature-induced periodontitis in rats.

123 al treatment with sFRP5 in mice subjected to ligature-induced periodontitis inhibited inflammation an

124 using a Porphyromonas gingivalis-associated ligature-induced periodontitis model in mice.

125 reduce periodontal disease severity in a rat ligature-induced periodontitis model.

126 Ligature-induced periodontitis resulted in significantly

127 esial/distal periodontal bone support at the ligature-induced periodontitis tooth areas.

128 Ligature-induced periodontitis was established in rats a

129 Ligature-induced periodontitis was examined in Goto-Kaki

130 d with ligature-induced peri-implantitis and ligature-induced periodontitis were similar.

131 rformed in rats: prevention and treatment of ligature-induced periodontitis with RvE1 topical treatme

132 phyromonas gingivalis-induced periodontitis, ligature-induced periodontitis, and aging-associated per

133 ngival plaque microbiota in the Nhp model of ligature-induced periodontitis, and that active immuniza

134 One week after ligature-induced periodontitis, the percentage of TLR4-p

135 duction, progression, and recovery phases of ligature-induced periodontitis.

136 sion using a nonhuman primate model of teeth ligature-induced periodontitis.

137 meters or proinflammatory cytokine levels in ligature-induced periodontitis.

138 zed with a P. gingivalis vaccine followed by ligature-induced periodontitis.

139 RvE1 treatment prevented bone loss in ligature-induced periodontitis.

140 l in in rats with diabetes mellitus (DM) and ligature-induced periodontitis.

141 tudy suggests that P. gingivalis exacerbates ligature-induced, RANKL-dependent periodontal bone resor

142 inhibitor) during periodontitis induction by ligature insertion in rats.

143 ); 3) STZ and melatonin (STZ+Mel, n = 8); 4) ligature (L, n = 6); 5) ligature and melatonin (L+Mel, n

144 ded into four groups: 1) control; 2) CsA; 3) ligature (Lig); and 4) ligature plus CsA (Lig + CsA).

145 In response to persistent subgingival ligature-mediated challenge, Rac-null mice had increased

146 Only the ligature model displayed significant alveolar bone loss

147 Furthermore, the blood cytokine response to ligature models showed their relevance for evaluating th

148 igature (Ocx+T; n = 10); and (6) Ocx, T, and ligature (n = 10).

149 without ligature (Ocx; n = 10); (4) Ocx and ligature (n = 10); (5) Ocx plus 250 mg/kg body weight in

150 ats in the healthy control group received no ligatures (n = 10).

151 Ligature occlusion of the artery did not decrease inulin

152 scular testosterone esters injection without ligature (Ocx+T; n = 10); and (6) Ocx, T, and ligature (

153 bone loss (n = 10); (3) orchiectomy without ligature (Ocx; n = 10); (4) Ocx and ligature (n = 10); (

154 ese include articles by Sir Astley Cooper on ligature of the common carotid artery for aneurysm, John

155 usion (I/R), and mouse hearts that underwent ligature of the left anterior descending coronary artery

156 nd ischemic conditions 7 days after complete ligature of the left anterior descending coronary artery

157 The Lig group received silk ligature on selected molars.

158 gingival inflammation 42% compared with the ligature only (P < 0.05), whereas vehicle alone had no e

159 Diathermy DCH was performed without pedicle ligature or anal-canal dressing, and a diclofenac suppos

160 clinical models: partial hepatectomy, portal ligature or embolization, and radiotherapy or chemothera

161 Surgical ligatures or fibrin sealants may be indicated in case of

162 issue compared with the control site without ligature ( P < 0.05), which was unaffected by local inje

163 rols included ligature alone (14 animals) or ligature + P. gingivalis (non-treatment; 15 animals).

164 75%; P <0.05) compared to the non-treatment (ligature + P. gingivalis) group, where significant perio

165 er canine teeth and fixed in place with wire ligature passing through holes in the flange and around

166 ntal breakdown was induced in a pre-clinical ligature periodontal inflammatory disease model.

167 ontrol rats (without ligature); 2) rats with ligature + placebo (saline; oral gavage); and 3) rats wi

168 ression induced by ligature, compared to the ligature + placebo group (P <0.05).

169 Compared to the ligature + placebo group, alveolar bone loss was reduced

170 Plaque was allowed to accumulate around wire ligatures placed into the defects.

171 Plaque was allowed to accumulate around ligatures placed into the defects.

172 crestal bone height at 3 and 6 months after ligature placement (P < .001 after 6 months).

173 ographic measurements at 3 and 6 months post-ligature placement and cessation of scaling.

174 Periodontitis was induced by ligature placement around the maxillary left second mola

175 wley) that have undergone loose, chromic gut ligature placement around the sciatic nerve.

176 ng at four days, but not six days, following ligature placement completely abolishes the hyperalgesic

177 Periodontitis was induced by ligature placement for 7 days, and vitamin K2 (30 mg/kg)

178 laque accumulation were encouraged with wire ligature placement for 8 weeks.

179 asts and percent eroded bone after 7 days of ligature placement was similar, while four days after re

180 tion, and periodontitis was induced via silk ligature placement with Porphyromonas gingivalis lipopol

181 in TNFalpha in the hippocampus at day 8 post-ligature placement, coincident with hyperalgesia.

182 ining the locus coeruleus (LC) at day 4 post-ligature placement, followed by an increase in TNFalpha

183 ere euthanized on days 0, 3, 7, and 10 after ligature placement, for a total of 12 experimental and 1

184 -2 expression increased at 21 days following ligature placement, in conjunction with MT1-MMP expressi

185 After ligature placement, increases were observed in PI, GI, P

186 Following ligature placement, the microbiota included a large prop

187 r 10 days, G1 and G3 were subjected to EP by ligature placement.

188 were performed in both groups 28 days after ligature placement.

189 ded at baseline and 1, 2, and 3 months after ligature placement.

190 Periodontitis was induced by ligature placement.

191 ed hippocampal slices isolated at day 8 post-ligature placement.

192 spinal cord are also increased at day 8 post-ligature placement.

193 ) control; 2) CsA; 3) ligature (Lig); and 4) ligature plus CsA (Lig + CsA).

194 eriodontitis was induced in C57BL/6J mice by ligatures previously incubated with Pg (LIGPG group) or

195 When REP was induced by removal of a CCA ligature, RCBF initially increased to 185% of baseline.

196 The mPI, and GI scores decreased after ligature removal (P < 0.001).

197 PD values were reduced following ligature removal (P < 0.05).

198 Ligature removal had a limited effect on the composition

199 initiation of gingival inflammation (before ligature removal), and 2 weeks and 4 weeks after ligatur

200 After ligature removal, rats in the Mel-Ped group were treated

201 After ligature removal, scaling, and a 2- to 4-week healing pe

202 After ligature removal, spontaneous resolution of gingival inf

203 After ligature removal, the PED group was given a single intra

204 e and 24 hours and 8 days after repair after ligature removal.

205 ture removal), and 2 weeks and 4 weeks after ligature removal: 1) plaque index (PI); 2) gingival inde

206 ore left anterior descending coronary artery ligature restored titin-based myocyte tension after MI,

207 mine effective IL-10 induction in vitro Silk ligatures (size 7-0) were tied around the mouse maxillar

208 ure and melatonin (L+Mel, n = 8); 6) STZ and ligature (STZ+L, n = 8); and 7) STZ, ligature, and melat

209 r periodontitis induction, first molars were ligatured submarginally for 4 weeks.

210 mes a week for a 6-week period to previously ligatured teeth.

211 first molar of the animals received a cotton ligature that was left in the same position for 14 days.

212 After removal of the ligature, the rats in the melatonin groups (EP-MEL, DM-M

213 as similar, while four days after removal of ligatures, the type 2 diabetic group had significantly h

214 In the control group without the ligatures, TLR4 was detected in 19% of the neurons in th

215 Attachment of ligature to a second maxillary molar induced DC-STAMP me

216 ls also underwent unilateral L5 spinal nerve ligature to induce sustained neuropathic pain behavior.

217 Plaque was allowed to accumulate around wire ligatures to create chronic disease.

218 mation in the diabetic periodontium by using ligatures to induce periodontitis in type-2 diabetic Got

219 In EP, a ligature was placed around maxillary second molars.

220 to the right lateral liver lobe, and a loose ligature was placed around the portal venous branch supp

221 For the EP groups, a ligature was placed around the right mandibular first mo

222 This stain disappeared if a ligature was placed on the dorsal root to block axonal t

223 doxycycline (6 mg/kg) for 21 days after the ligature was placed.

224 After 7 days, the ligature was removed, and the animals were distributed i

225 After 7 days, the ligature was removed, and the rats were randomly divided

226 Silk ligatures were applied to the maxillary second molars in

227 create experimental periodontitis, 4/0 silk ligatures were inserted submarginally around first molar

228 Cotton ligatures were next placed around the healing-abutments

229 The ligatures were placed 30 days postorchiectomy (or sham-o

230 Silk ligatures were placed around the cervical area of the ma

231 Wire ligatures were placed into these defects for plaque accu

232 Silk ligatures were placed subgingivally around the mandibula

233 At the same time, P. gingivalis-soaked ligatures were placed subgingivally around the maxillary

234 s of the right hind limb was ligated and the ligatures were released after a predetermined period of

235 Ligatures were removed after 7 days, and rats were then

236 Three weeks later, the ligatures were removed and 4 different treatment modalit

237 Ligatures were removed from the second molars on day 14,

238 After 2 mos, the ligatures were removed, and a notch was placed at the ba

239 After 30 days, ligatures were removed, dogs were placed on a hard diet

240 After 2 months, the wire ligatures were removed, the teeth and roots scaled and r

241 After 2 months, the ligatures were removed, the teeth were scaled and root p

242 r all experimental teeth after delivery, and ligatures were removed.

243 ere repeated at 10 months post-baseline, and ligatures were removed.

244 Ligatures were tied around selected teeth to initiate or

245 cal evaluation was performed, and additional ligatures were tied on teeth in the contralateral quadra

246 We showed that after the removal of ligatures, which induces resolution of periodontal infla

247 Wistar rats were subjected to ABR by ligature with nylon thread in the second upper-left mola