ライフサイエンスコーパス: light sensitivity

1 sulting in plants with dramatically enhanced light sensitivity.

2 rements in TOC1 gene dosage clearly enhanced light sensitivity.

3 s to produce similar shifts in ganglion cell light sensitivity.

4 100-fold shift in the threshold for far-red light sensitivity.

5 nd demonstrate that its truncation causes UV light sensitivity.

6 photoreceptors with outer-segment discs and light sensitivity.

7 50-fold, resulting in a >10-fold decrease in light sensitivity.

8 ow on- and off-latencies, and relatively low light sensitivity.

9 ponse to light, positive masking, has normal light sensitivity.

10 seven-TM protein structure for retinal-based light sensitivity.

11 in bipolar cells dynamically control retinal light sensitivity.

12 tions 10-fold higher than required to impart light-sensitivity.

13 er time than players without these symptoms: light sensitivity (16.0 vs 3.0 days, P = .001), emotiona

14 rminus plays an important role in modulating light sensitivity and activity of the protein.

15 phosphodiesterase (LAPD) with complementary light sensitivity and catalytic activity by recombining

16 Many of the humans demonstrated increases in light sensitivity and in visual acuity.

17 (a proxy for cell size) and IR, and between light sensitivity and IR, with larger and more sensitive

18 nd higher input resistance, yet showed lower light sensitivity and lower maximal light responses than

19 this study is responsible for increasing the light sensitivity and operational range of rod bipolar c

20 Here we report a mechanism that controls the light sensitivity and operational range of rod-driven bi

21 hodopsin actuator, CheRiff, which shows high light sensitivity and rapid kinetics and is spectrally o

22 ide-mediated photocurrents that maintain the light sensitivity and reversible, step-like kinetic stab

23 lar specialization and show an extremely low light sensitivity and sluggish kinetics.

24 mediated by viral gene therapy, can restore light sensitivity and some vision to mice blind from out

25 ogenetic inhibition tools with unprecedented light sensitivity and temporal precision.

26 Light sensitivity and the involvement of unstable protei

27 h the appropriate illumination, AAQ restores light sensitivity and visual behavior.

28 the electroretinogram was normal in terms of light sensitivity and waveform, but the light threshold

29 se variants have altered spectral responses, light sensitivity, and channel selectivity.

30 n vision), in 99% for ocular symptoms (pain, light sensitivity, and discomfort), and in 95% for dryne

31 s also resulted in leaf chlorosis, increased light sensitivity, and dwarfism due to decreased levels

32 ates under high light intensities, increased light sensitivity, and lower PSII efficiency, without af

33 utant shows: (i) slower growth rates, higher light sensitivity, and reduced amounts of PS I; (ii) a r

34 s to use existing neuronal tissue to restore light sensitivity, and to augment existing strategies to

35 Interestingly, light sensitivity appeared to correlate with the concent

36 n, with ChR2-EYFP and Arch-ER2 demonstrating light sensitivity approaching that of in utero or virall

37 These light sensitivities are virtually identical to those of

38 -year-old child had nearly the same level of light sensitivity as that in age-matched normal-sighted

39 Pld(null) flies exhibit decreased light sensitivity as well as a heightened susceptibility

40 Furthermore, the light sensitivity associated with levels of the TIM prot

41 The differential light sensitivities at the 10 most sensitive locations f

42 on of retinal dopamine in goldfish increases light sensitivity at photopic backgrounds.

43 nstructed a hypothesis for the regulation of light sensitivity at the level of rod synapse.

44 slowing of visual processing would increase light sensitivity but should also reduce movement respon

45 synaptic lateral inhibition to ganglion cell light sensitivity by measuring the effects of surround i

46 led theoretical ChR2 variants with augmented light sensitivity (ChR2+), red-shifted spectral sensitiv

47 nical visual assessment, were used to assess light sensitivity, contrast sensitivity and spatial acui

48 roperties do not contribute to the intrinsic light sensitivity differences between rods and cones.

49 The unit of differential light sensitivity (DLS) in perimetry is the decibel.

50 Differential light sensitivity (DLS) in white-on-white perimetry is u

51 r evidence that the mutation mainly enhances light sensitivity downstream of phytochrome A (phyA) and

52 t RP patients demonstrated possible improved light sensitivity during the initial months of follow-up

53 The acceptable light sensitivity, favorable spectral sensitivity, and s

54 account for the persistence of the increased light sensitivity following retinal dopamine depletion.

55 ready published by Medeiros et al. combining light sensitivities from SAP and retinal thickness from

56 Due to its high operational light sensitivity, iChloC makes it possible to inhibit n

57 The general hypothesis of increased light sensitivity in bipolar patients was not supported.

58 We also show that restoration of light sensitivity in rd10 rods is attributable to assemb

59 s of constitutive skin color and ultraviolet light sensitivity in relation to risk of cutaneous malig

60 prolonged dark adaptation leads to increased light sensitivity in rods by dissociating RGS9-1 from R9

61 ed expression of a ChR2 variant with greater light sensitivity in SGNs reduced the amount of light re

62 ll responses in these animals have a reduced light sensitivity in the dark-adapted state.

63 improvements in mean mobility and full-field light sensitivity in the injected eye by day 30 that per

64 low luminance deficit, contrast sensitivity, light sensitivity in the macula, and rod-mediated dark a

65 hotoreceptors, is widely assumed to regulate light sensitivity in the rod outer segment through inter

66 s of opsins evolved a seven-TM structure and light sensitivity independently.

67 conceptual design strategies for installing light sensitivities into the immune signaling network an

68 Engineering light-sensitivity into proteins has wide ranging applica

69 Light sensitivity is restored to the resulting apo-opsin

70 Light sensitivity is restored when apo-opsin combines wi

71 RH1 and RH2 visual pigments with the optimum light sensitivities (lambdamax) at 478 nm and 485 nm, re

72 y, the data indicate that sex differences in light sensitivity might play a key role for ensuring the

73 rate that zTrpa1b/ligand pairing offers high light sensitivity, millisecond-scale response latency in

74 ted Arabidopsis plants with greatly enhanced light sensitivity, mutants variably altered in Pfr-to-Pr

75 We found that the light sensitivities of presynaptic, inhibitory pathways

76 protoporphyrin IX dramatically increased the light sensitivity of both TRPA1 and TRPV1 via generation

77 The light sensitivity of cone ERGs of BALB/c mice, which had

78 n is explained by natural alleles that alter light sensitivity of GI, specifically in the evening, an

79 t pulses and for orders-of-magnitude-greater light sensitivity of inhibited cells.

80 reased the rate of maintained firing and the light sensitivity of ON ganglion cells.

81 Chromophore regeneration kinetics, light sensitivity of photoreceptors, and phototransducti

82 receptor co-action mechanism to sustain blue light sensitivity of plants under the broad spectra of s

83 multiple molecular mechanisms regulating the light sensitivity of rods and cones.

84 G90D decreased the light sensitivity of rods but spared them from severe re

85 s effects, 67RuvC constructs suppress the UV light sensitivity of ruvA, ruvAB and ruvABC mutant strai

86 at the photopigment underlying the intrinsic light sensitivity of SCN-projecting RGCs has an absorpti

87 This response pattern paralleled the blue light sensitivity of stomatal opening in the two leaf su

88 leucine-rich repeats-that result in reduced light sensitivity of the circadian clock.

89 er surround illumination further reduced the light sensitivity of the ganglion cell.

90 Microperimetry allows mapping of light sensitivity of the macula and provides topographic

91 To measure and analyze retinal light sensitivity of the macula in STGD1 using fundus-co

92 e examined light signaling by exploiting the light sensitivity of the Neurospora biological clock, sp

93 Light sensitivity of the opsin pigment is restored throu

94 on and amacrine cells without destroying the light sensitivity of the retina by maximally activating

95 sitive detection of GFP while preserving the light sensitivity of the retina, and can be used to obta

96 Because of the selective blue light sensitivity of the retinal ganglion cells governin

97 Light sensitivity of this organ is epitomized in the flu

98 DENAQ confers light sensitivity on a hyperpolarization-activated inwar

99 Melanopsin is the photopigment that confers light sensitivity on intrinsically photosensitive retina

100 Brief application of AAQ bestows prolonged light sensitivity on multiple types of retinal neurons,

101 Photoswitch compounds such as DENAQ confer light-sensitivity on endogenous neuronal ion channels, e

102 Here we describe a method for bestowing light sensitivity onto endogenous ion channels that does

103 We showed that PAL treatment confers light sensitivity onto endogenous K+ channels in isolate

104 Azobenzene photoswitches confer light sensitivity onto retinal ganglion cells (RGCs) in

105 llular Mg2+ has no significant effect on the light sensitivity or the kinetics of the photoresponse.

106 e mechanisms will maximize a photoreceptor's light sensitivity range and therefore may be common in o

107 We characterize light sensitivity recovery in continuously illuminated w

108 dividual traits, such as sex-differences, on light sensitivity remains to be established.

109 Restoration of light sensitivity requires chemical re-isomerization of

110 Restoration of light sensitivity requires chemical reisomerization of r

111 ion could overcome nearly all of the loss of light sensitivity resulting from the biochemical blockad

112 Dryness and light sensitivity scales were then calculated, summed, a

113 The arr mutants show altered red light sensitivity, suggesting a general involvement of t

114 ications, and newer issues such as Transient Light Sensitivity Syndrome are safety concerns of flap c

115 ons of femtosecond lasers included transient light-sensitivity syndrome, rainbow glare, opaque bubble

116 as diffuse lamellar keratitis and transient light-sensitivity syndrome.

117 rd mice showed significantly lower pupillary light sensitivity than rd/rd mice alone.

118 t length on the basis of circadian rhythm of light sensitivity that is set from dusk, early flowering

119 included two symptom questions (dryness and light sensitivity) that inquired about frequency and int

120 To restore light sensitivity, the all-trans-retinaldehyde must be c

121 ons and clinical measures such as full-field light sensitivity threshold for white, red, and blue col

122 ular pattern of axonal connections, enhances light sensitivity through the principle of neural superp

123 e developed a new chemical gate that confers light sensitivity to an ion channel.

124 Restoring light sensitivity to apo-opsin requires thermal re-isome

125 retinal ganglion cells, primarily conferring light sensitivity to bipolar cells.

126 onstrate the utility of TULIPs by conferring light sensitivity to functionally distinct components of

127 er with earlier studies linking variation in light sensitivity to photoreceptor genes, our work sugge

128 e cells as a possible strategy for imparting light sensitivity to retinas lacking rods and cones.

129 Restoration of light sensitivity to the apo-opsin involves the conversi

130 Restoration of light sensitivity to the bleached opsin requires chemica

131 Restoration of light sensitivity to the bleached opsin requires chemica

132 orhodopsin, a rod photopigment, and restored light sensitivity to the electroretinogram.

133 ed by gene therapy, we related the degree of light sensitivity to the level of remaining photorecepto

134 etic small molecule photoswitch, can restore light sensitivity to the retina and behavioral responses

135 e assays, we further show that JB253 bestows light sensitivity upon rodent and human pancreatic beta

136 This enhanced light sensitivity was more exaggerated in a relatively l

137 However, light sensitivity was reduced by approximately fourfold

138 In single cell recordings rod light sensitivity was shown to be a function of the amou

139 125A mutant, which exhibited slow growth and light sensitivity, was used to isolate suppressor strain

140 constitutive skin color and skin ultraviolet light sensitivity were assessed by colorimetry and minim

141 -retinaldehyde and the recovery rate for rod light sensitivity were faster in FATP4-deficient mice th

142 Somewhat surprisingly, dark current and light sensitivity were normal in individual rods (record

143 ated Ca(2+) release from internal stores and light sensitivity were strongly attenuated.

144 ese two changes may be of importance for dim light sensitivity, which is consistent with our proposal