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2 Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by
3 None of the other monitored Fusarium toxins like 15-acetyldeoxynivalenol, HT2- and T2-toxin, zearale
5 ygous missense mutations affecting exostosin-like 3 (EXTL3), a glycosyltransferase involved in hepara
6 ible for induction of the Notch ligand delta-like 4 (DLL4) in endothelial cells, we find that activat
9 y the hydrophobic carbonaceous matrix acting like a filter favoring the release into water of carboxy
12 nterface demonstrated that the biofilm flows like a viscous liquid under high flow velocities applied
16 underlying mechanism of this intriguing gas-like adhesion is the configurational entropy difference
25 sis supported a two-component model of humic-like and nonhumic-like dissolved organic matter (DOM).
26 what an active TAM receptor kinase may look like and suggesting a potential role for the juxtamembra
27 r two filament connections act as transistor-like, angle dependent momentum filters, whereas triangul
28 B mRNA editing enzyme catalytic polypeptide-like APOBEC3A and APOBEC3B have emerged as key mutation
29 nown to promote somatic embryogenesis, which like apogamy produce sporophytes without fertilization.
31 s, we report an iridium-catalysed tyrosinase-like approach to catechols, employing an oxyacetamide-di
35 kinase (Ampk) at tyrosine 172 and of unc-51 like autophagy activating kinase 1 (Ulk1) at serine 555.
36 iven gene expression to construct a 'species-like' barrier to reproduction between two otherwise comp
37 harbor bacterial, viral and parasitic agents like Bartonella sp., Phleboviruses and Leishmania spp.,
38 anxiety-like behavior, decreased depression-like behavior and increased preference for rewarding sti
40 r (OXR) antagonists on measures of impulsive-like behavior in rats were evaluated using the five-choi
41 e mutant animals displayed increased anxiety-like behavior in the elevated plus maze and in a light/d
42 cterized by hyperactivity, decreased anxiety-like behavior, decreased depression-like behavior and in
45 s Twist1 expression is associated with basal-like breast cancer (BLBC) with poor prognosis owing to i
46 Products of bacterial anaerobic metabolism, like butyrate and other short-chain fatty acids (SCFAs),
47 ), followed by the bronchi, endocrine glands-like C cells of the thyroid (medullary carcinoma), the p
50 remained unknown if, and how, calcineurin B-like calcium sensors (CBLs) and CBL-interacting protein
51 capsule represents the first man-made enzyme-like catalyst that is capable of catalyzing this reactio
52 AgNPs/oxMWCNTs showed excellent peroxidease-like catalytic activity in hydrogen peroxide-Amplex red
53 c interactions, while the FtSaBs behave more like cations that strongly associate with the solid phas
55 luripotent stem cells (iPSCs) and hepatocyte-like cells (HLCs) for genome-wide mapping of expression
56 directly reprogrammed induced cardiomyocyte-like cells (iCMs) by overexpression of Gata4, Mef2c, and
58 Thus, the dichotomy between T-like and B-like cells and the presence of dedicated lymphopoietic t
59 ementum in GACI teeth, including cementocyte-like cells and unusual patterns of cementum resorption a
62 ossibility that resident macrophage/monocyte-like cells in the cochlea can mediate local autoinflamma
63 that a population of Thy1.2(+) non-NK innate-like cells present in the liver expresses IFN-gamma and
64 abnormal oral adhesions maintained periderm-like cells that express keratin 6, but we observed abnor
65 of benchmarking stem cell-derived hepatocyte-like cells to their terminally differentiated human coun
71 These results further demonstrate the prion-like characteristics of alphaS and reveal its efficiency
72 receptor (GCGR) are members of the secretin-like class B family of G-protein-coupled receptors (GPCR
75 opic and nematic (I + N) coexistence for rod-like colloids is a signature of the first-order thermody
77 dehydrogenations typically occur in a domino-like conversion process during the thermal annealing, th
79 a: see text], the more uniform, with systems like crystals achieving the maximum value: [Formula: see
84 les: an N-terminal sugar phosphate isomerase-like domain associated with DSD activity and a novel C-t
88 mers polymerize head to tail forming tubulin-like dynamic protofilaments, whose organization in the Z
89 ural systems to a periodic external forcing, like e.g. seasonal forcing in ecology and climate scienc
91 agonist INT-767 induced caloric restriction-like effects and reversed age-related increases in prote
92 Here, we demonstrate that the antidepressant-like efficacy of three unique drugs, with reported rapid
95 both cell types resulted in a lethal sepsis-like environment, which included tissue inflammation and
99 he CC composition and explored PEG and islet-like extracellular matrix (Matrigel; MG) islet encapsula
100 e often related to geometrically large parts like face outline and hair, preference and anti-preferen
104 bioavailability, ADMET risk filter for drug like features, and synthetic accessibility for chemical
105 P2 T158M expression ameliorated multiple RTT-like features, including motor dysfunction and breathing
106 indexes that correspond to a group of humic-like fluorescing species were determined to be highly co
107 t while arginine substitutions had wild-type-like fusion levels in an in vitro gB/gH-gL cell fusion a
108 enetic and expression analysis for eight SEP-like GERBERA REGULATOR OF CAPITULUM DEVELOPMENT (GRCD) g
109 high affinity to GDNF family receptor alpha-like (GFRAL), a distant relative of receptors for a dist
110 re we report that GDNF-family receptor alpha-like (GFRAL), an orphan member of the GFR-alpha family,
111 mpaired in patients with common eye diseases like glaucoma and age-related macular degeneration.
112 showed up-regulation of beta-catenin targets like glutamine synthetase (GS), leukocyte cell-derived c
113 uality when paired with researchers who look like "good scientists." Our findings offer insights into
115 on reversible mechanisms identified Insulin-like growth factor (IGF1) deficiency with inadequate com
118 riables, including glucose, insulin, insulin-like growth factor I, triglycerides, cholesterol, cortis
121 its metabolites in combination with insulin-like growth factor-1 are shown to promote the corneal ep
124 more physiologically relevant cardiac tissue-like in vitro models for mechanistic biological research
127 genotyped for TAS2R38 status to determine if liking is influenced by perception of bitter compounds s
131 opose that the concerted action of DDK, Polo-like kinase, and CDK1 promotes efficient SC destruction
132 tein Kinases (previously referred to as MUT9-like kinases) interact with and phosphorylate photoexcit
134 ere the oil remained connected in thin sheet-like layers in the narrower regions of the pore space.
136 e that the striking difference in compulsive-like locomotor behavior is also based on differential VT
137 tural killer T cells (iNKT cells) are innate-like lymphocytes that protect against infection, autoimm
138 presence of clinically relevant slow growers like M. kansasii, M. szulgai, M. gordonae, and M. asiati
139 um; however, in these samples, rapid growers like M. mageritense occurred at much higher relative abu
140 /PML axis elevates intratumoral Tregs and M2-like macrophages and reduces CD8+ T cells to promote lun
146 the activated B cells and circulating tissue-like memory B cells, and expansion of the B regulatory c
147 executed by the mixed lineage kinase domain-like (MLKL) protein, which is triggered by receptor-inte
150 We found that the SUMO (small ubiquitin-like modifier)-modification and ubiquitin-proteasome sys
151 ing assays revealed that the arthropod HSP70-like molecule contributes to differential fibrinogenolys
152 molecules, drugs, drug metabolites and drug-like molecules, including salicylates and diclofenac, as
153 termine that zone I displays an orthorhombic-like monoclinic structure with space group of Cm (=8).
154 lt-born neuron with initially simple spindle-like morphology develops into a DGC, consisting of a sin
157 itration calorimetry, we found that Munc18c, like Munc18a, binds to both the closed conformation and
159 tive mutants of protein-tyrosine phosphatase-like myo-inositol phosphatases (PTPLPs) from the non-pat
160 .The huge amount of data generated in fields like neuroscience or finance calls for effective strateg
166 ty of vegetables during breastfeeding on the liking of vegetables in both members of the dyad.We cond
167 ses that establish a nonreactivating, latent-like or a replicative infection in CD34(+) hematopoietic
172 a proton relay mechanism between a ketone-like oxygen and a pyridine-like nitrogen across the vaca
173 sensitivity to Cav1.3 variants during SN DA-like pacemaking compared with Cav1.2 during aSM-like act
174 conditions, the activation of myofibroblast-like pancreatic stellate cells (PSCs) plays a predominan
175 ies elicited by immunization via Pfs25 virus-like particles in human immunoglobulin loci transgenic m
179 stric inhibitory polypeptide (GIP), glucagon-like peptide 1 (GLP-1), and peptide tyrosine tyrosine (P
182 ting to controllably release GLP-1 (glucagon-like peptide 1), a critical incretin that regulates bloo
184 ng-acting analog of the gut-hormone glucagon-like peptide-1 highlights the therapeutic potential of g
186 pocampal neurons to reduce (leptin, glucagon-like peptide-1) or increase (ghrelin) food intake and le
191 7 and Th1 cells (nTh17 and nTh1) with innate-like phenotype have been identified in the thymus that a
193 We report that RAC1(P29S) evokes a Rasopathy-like phenotype on zebrafish development that can be bloc
194 of conversion of melanocytes to a metastatic-like phenotype only previously observed in an all-or-non
198 the periphery of the mouse to cause migraine-like photophobia by apparently distinct mechanisms.
205 n addition to suppressing migratory and stem-like properties of tumor cells, also inhibit endothelial
208 osphorylation of mixed-lineage kinase domain-like protein (MLKL), which results in disruption of the
210 ocalization dependent on MinD and the DivIVA-like protein Cdv3, indicating that two distinct pools of
211 hich Iw1 acts to suppress a carboxylesterase-like protein gene, W1-COE, within the W1 multigene locus
212 rabidopsis (Arabidopsis thaliana) Shewanella-like protein phosphatase 2 (AtSLP2) is a bona fide Ser/T
213 covalent attachment of prokaryotic ubiquitin-like protein Pup to lysine side chains of the target pro
214 tructure and stability of VVTL1, a Thaumatin-like protein purified from wine, was analyzed by Synchro
217 ed sites included inductions of vitellogenin-like proteins in male organisms, inductions of Na(+)K(+)
220 status (specifically acute, Koch phenomenon-like reactions), lung function, or radiology attributabl
223 ed that NS1-mediated inhibition of the RIG-I-like receptor (RLR) signaling pathway involves inhibitio
225 n and activation of the inflammasome by Toll-like receptor (TLR) agonism with bacterial lipopolysacch
228 trate that hRetn binds the LPS receptor Toll-like receptor 4 (TLR4) through its N terminal and modula
230 leotide-binding oligomerization domain (NOD)-like receptor C4 (NLRC4) were associated with neutrophil
231 ostate cancer cells stably adorned with Toll-like receptor-9 ligand-loaded particles using streptavid
232 oteobacteria phyla, we found that potent Nod-like receptor-stimulating bacteria in the upper airway (
235 erapies based on activation of multiple Toll-like receptors (TLRs) may offer superior therapeutic pro
240 on of circulating microbial products by Toll-like receptors on T cells, and this regulation is conser
241 r proinflammatory cytokines and various toll-like receptors were overexpressed in SAH neutrophils com
244 Molecular genetic analysis of the switch-like regulation of daf-7 expression in the ASJ neuron pa
245 residues 60-550 that indicates that the TPR-like repeats of the M-region extend to residue 137 and t
247 h leads to bistability and allows for switch-like responses to inputs, is nested within a negative fe
248 s were found for genotypes native to Mexico (like RIM105, M031, and M033) or from Peru and Ecuador (I
249 lated BMI1 and other polycomb group proteins like RING1A, RING1B, EZH2 and also altered the expressio
250 intercross." Chemically synthesized genomes like Sc2.0 are fully customizable and allow experimental
251 r time and persisted in forming hypertrophic-like scars, whereas few CD26-positive cells were present
252 st that cognitive abnormalities in disorders like schizophrenia in which gluatamatergic signalling is
253 ling FKBP proteins contain a C-terminal KDEL-like sequence, bind ST-FRB in the Golgi, and are transpo
258 preference to engage with a top-heavy, face-like stimulus when contrasted with all other forms of st
260 inate by forming a highly hierarchical chain-like structure of homogeneously clustered anatomical are
261 tures, including the sheet-on-sheet sandwich-like structure, ultrathin nanosheets with abundant nanop
262 quipping the hotspot with a molecular beacon-like structure, we combine the plasmonic signal enhancem
264 de silicon using 1 microm-sized dots and rod-like structures of adjustable length as basic building b
267 AIT) cells are a recently discovered, innate-like subset of T cells with cytotoxic function, the role
269 solved compounds, often referred to as humic-like substances (HULIS), which influence particle proper
270 was associated with increased risk of basal-like subtype [OR 4.17; 95% confidence interval (CI) 1.89
271 or those same metrics, and exhibiting sprawl-like suburban development), our models suggest that Chri
272 ide effects, such as sedation and depression-like symptoms, than other dopamine receptor antagonists.
275 TORC2 but not mTORC2 alone develop a Fanconi-like syndrome of glucosuria, phosphaturia, aminoaciduria
285 e global causes of lower respiratory disease like the parainfluenza viruses, as well as agents of let
286 l changes with catalysis in modular enzymes, like the PMT, provides new insights on interdomain commu
288 ield anomaly is a field-induced metamagnetic-like transition and affects both magnetisation and magne
289 tion: the eIF4E-binding Panicum mosaic virus-like translational enhancer (PTE) and ribosome-binding 3
290 gates this problem and can help achieve band-like transport on a wide range of substrate platforms.
291 compatibility with valuable functionalities like triflates and mesylates for follow-up reactions as
292 ure-guided design to develop improved native-like trimers that reduce exposure of non-nAb epitopes in
294 abeling of proteins with ubiquitin/ubiquitin-like (Ubl) proteins is crucial for several physiological
295 tes cells and growth factors within a muscle-like unidirectionally ordered environment of nanofibers.
296 like units, and 1 lysine-substituted elastin-like unit) with GAG GM-0111, we created an injectable de
297 ains 6 repeats of blocks comprised of 8 silk-like units, 15 elastin-like units, and 1 lysine-substitu
298 s comprised of 8 silk-like units, 15 elastin-like units, and 1 lysine-substituted elastin-like unit)
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