1 RES-CreERT2 (Alpi(CreER)) knockin allele for
lineage tracing.
2 ntial of c-kit(+) cells by inducible genetic
lineage tracing.
3 n, and to revisit the same cells for in vivo
lineage tracing.
4 he dorsal aspect of the prostatic urethra by
lineage tracing.
5 precision of conventional Cre-loxP-mediated
lineage tracing.
6 he Cell Stem Cell tenth anniversary theme of
lineage tracing.
7 Recent technological advances in
lineage tracing allow us for the first time to study the
8 based on statistical analysis of multicolor
lineage tracing,
allowing the definition of multipotency
9 Lineage tracing also revealed that the progeny of indivi
10 Lineage tracing analyses and knock-in transgenic mice ha
11 Using
lineage-tracing analyses, we demonstrate that sub-epicar
12 Employing
lineage-tracing analyses, we have now identified Notch e
13 Genetic
lineage tracing analysis demonstrates that tissue-reside
14 Lineage tracing analysis revealed the conversion of beta
15 By
lineage tracing analysis, we also found that collagen-ex
16 2) were crossed with Rosa26-LSL-YFP mice for
lineage tracing analysis.
17 Lineage-tracing analysis revealed that descendants of Sf
18 ining a tamoxifen-inducible Cre for cellular
lineage-tracing analysis.
19 use next generation sequencing for antibody
lineage tracing and B cell fate mapping.
20 We take a quantitative approach combining
lineage tracing and biophysical modeling and address how
21 h the origin(s) of infarct fibroblasts using
lineage tracing and bone marrow transplants and a robust
22 ore this question, we have performed genetic
lineage tracing and clonal analysis of individual cells
23 Here we use molecular markers,
lineage tracing and clonal analysis to map alveolar prog
24 We use cell
lineage tracing and combinations of tissue-specific mark
25 eye formation in Doryteuthis pealeii Through
lineage tracing and gene expression analyses, we demonst
26 Here, we use
lineage tracing and gene expression mapping to show that
27 Here we show through
lineage tracing and genetic ablation that BMI1(+) CSCs m
28 Here, we combine molecular mapping,
lineage tracing and genetic analysis in the adult fruit
29 es of differentiation, neuropil development,
lineage tracing and hierarchies of fates in the developi
30 Lineage tracing and immunohistochemical analyses reveale
31 Using in situ genetic
lineage tracing and limiting dilution transplantation, w
32 Here, we first demonstrated by cell
lineage tracing and mineral double-labeling approaches t
33 Here we use cell
lineage tracing and multiple in vivo approaches to study
34 hages by marker expression patterns, genetic
lineage tracing and parabiosis.
35 Using a combination of
lineage tracing and pulse-chase of actively proliferatin
36 Lineage tracing and quantitative clonal analysis reveal
37 Here, we employed in vivo
lineage tracing and real-time gene expression transgenic
38 In vivo
lineage tracing and serial transplantation assays showed
39 -expressing osteolineage cells, we performed
lineage tracing and showed that they sustain bone format
40 Using a combination of cell ablation,
lineage tracing and signalling pathway modulation, we sh
41 Lineage tracing and time-lapse microscopy reveal that Lg
42 Techniques including cell-
lineage tracing and transcriptome analysis have provided
43 We also review the use of recent
lineage tracing and transcriptomic approaches to revisit
44 ociated with NK T cell development, by using
lineage tracing and transfer studies.
45 Lineage tracing and transplantation assays demonstrate t
46 Using in vivo
lineage tracing and triple negative breast cancer (TNBC)
47 In zebrafish, previous
lineage-tracing and mutant analyses suggested that SHF v
48 Using genetic
lineage-tracing and neural crest-deficient mutants in ze
49 Using multicolor
lineage-tracing and organoid-formation assays, we identi
50 Using genetic
lineage-tracing and scanning-block face electron microsc
51 origin of melanoma, we combined single-cell
lineage-tracing and transcriptomics approaches with time
52 nalyzed by confocal and electron microscopy,
lineage tracing,
and fluorescence-activated cell sorting
53 ese questions through in situ hybridization,
lineage tracing,
and genetic experiments.
54 coding, single cell transplantation, in vivo
lineage tracing,
and HSC-specific pulse-chase labeling h
55 We employ genetics, cell
lineage tracing,
and single molecule imaging to show tha
56 ressing green fluorescent protein, to enable
lineage tracing,
and subjected mice to a biophysical sti
57 Next, using a genetic
lineage tracing approach, we demonstrated these progenit
58 The cartilage-specific cell
lineage-tracing approach in triple mice containing Rosa
59 A novel
lineage-tracing approach now identifies a subset of muri
60 is healing, Gli1 expression was examined via
lineage tracing approaches and the effect of Smo deletio
61 studies using cellular markers, but recently
lineage tracing approaches have proven that cells are hi
62 However, current
lineage-tracing approaches scale poorly to whole, comple
63 Using genetic
lineage-tracing approaches, we show that in the postnata
64 capable of describing the results of recent
lineage tracing assays involving epithelial tissues.
65 Here, using
lineage-tracing assays in a transgenic zebrafish model o
66 Through the combination of long-term
lineage-tracing assays with short-term in vivo live imag
67 high confidence, and the second one based on
lineage tracing at saturation to assess the fate of all
68 In the mouse pancreas,
lineage tracing at the population level has shown that t
69 Lineage tracing by using Cdh5cre(ERt2)/Rosa-YFP reporter
70 e wide-ranging applications, such as in deep
lineage tracing,
cellular barcoding, molecular recording
71 Immunostaining,
lineage tracing,
clonal analysis, and live imaging showe
72 Employing a combination of
lineage tracing,
clonal analysis, and organoid culture a
73 erform either double lineage tracing or cell
lineage tracing combined with gene manipulation in a sec
74 We used
lineage tracing,
conditional deletion, mosaic analysis a
75 In vitro
lineage tracing confirmed that BMP-7-induced insulin-exp
76 Lineage tracing confirmed that LDB1-depleted, insulin-ne
77 Lineage tracing confirms the adipocyte origin of Ad/N1IC
78 Genetic
lineage tracing confirms the presence of the Tbx6(+) NMP
79 Genetic
lineage-tracing confirms that odontoma form in a similar
80 n the intestinal epithelium, and a year-long
lineage-tracing course revealed that genetic blockade of
81 Using in-vivo
lineage tracing data we quantified clonal expansion as w
82 Lineage tracing demonstrated no contribution of HNF1beta
83 Cell
lineage tracing demonstrated that mesodermal mesenchymal
84 Lineage tracing demonstrated that multiple SI stem cell
85 Lineage tracing demonstrated the critical role of CD133
86 Lineage tracing demonstrates that this regeneration deri
87 Lineage tracing distinguished macrophages from classical
88 igorous control of Cre-loxP recombination in
lineage tracing,
effectively circumventing potential unc
89 Thus, live imaging and
lineage tracing enabled us to clarify precisely how MCs
90 This study provides direct
lineage tracing evidence that a cardiomyoblast populatio
91 We performed
lineage tracing experiments and analyzed mutants lacking
92 nic and knock-in Cre drivers used to perform
lineage tracing experiments are often dynamically, tempo
93 Lineage tracing experiments demonstrate that the non-neu
94 Tbx1
lineage tracing experiments demonstrated a specific regi
95 Lineage tracing experiments have mapped the heritage, id
96 Recently, genetic
lineage tracing experiments have revealed chondrocyte pr
97 Lineage tracing experiments in Foxc1 mutant mouse cerebe
98 Lineage tracing experiments indicate that HSCs emerge fr
99 Recent
lineage tracing experiments indicated that the LSC is SR
100 Lineage tracing experiments of the gastric corpus in mic
101 Lineage tracing experiments revealed accumulation of ex-
102 Lineage tracing experiments show that Bglap-expressing c
103 Furthermore, our long-term
lineage tracing experiments show that cerebellar Olig ge
104 Lineage tracing experiments show that GATA/CD24hi cells
105 Using enhancer trap and Cre transgenes, our
lineage tracing experiments show that in Wnt5a null mice
106 Lineage tracing experiments show that, following irradia
107 oit a Prdm1.CreERT2-LacZ reporter allele for
lineage tracing experiments.
108 fferentiation process was validated by using
lineage-tracing experiments based on Sox18Cre(ERt2)/Rosa
109 However,
lineage-tracing experiments demonstrate that cells from
110 Recent
lineage-tracing experiments have demonstrated that these
111 Using complementary
lineage-tracing experiments in E(z) mutant testes, a por
112 Here, by
lineage-tracing experiments in fetal or postnatal mice,
113 We performed cell
lineage-tracing experiments in mice that expressed a gai
114 In vivo
lineage-tracing experiments in molars showed the contrib
115 Lineage-tracing experiments indicated that the majority
116 Lineage-tracing experiments revealed that Dicer1 deficie
117 Lineage-tracing experiments revealed that PW1(+) cells d
118 Lineage-tracing experiments revealed that the cells that
119 Lineage-tracing experiments revealed that the Gli1 linea
120 titute a complete prostate gland, yet murine
lineage-tracing experiments show that luminal cells gene
121 Cell
lineage-tracing experiments showed that ADAM10 is requir
122 Lineage-tracing experiments showed that cells initially
123 Lineage-tracing experiments to map the fate of Wt1(+) PM
124 However,
lineage-tracing experiments using an inducible Tbx18-Cre
125 We recently published genetic
lineage-tracing experiments using the Fezf2 and Cux2 loc
126 of regenerating hepatocytes using short-term
lineage-tracing experiments, as well as the inducible Cr
127 Utilizing transgenesis,
lineage tracing,
flow cytometry, and immunostaining tech
128 Here we use single cell
lineage tracing following stochastic transforming growth
129 Here we test this method using genetic
lineage tracing for expression of endogenous Nanog and O
130 Genetic manipulations, with or without
lineage tracing for specific pancreatic cell types, are
131 vide the first direct evidence using genetic
lineage tracing for two basic assumptions in Schwann cel
132 reased epidermal proliferation with expanded
lineage tracing from epidermal stem cells positive for L
133 ys combined with gene-expression studies and
lineage tracing further demonstrated that this signaling
134 By combining
lineage tracing,
genetic cell ablation, and confocal liv
135 enome editing of synthetic target arrays for
lineage tracing (
GESTALT) can be used to generate large-
136 Lineage tracing has become the method of choice to study
137 In the lung,
lineage tracing has been used to identify distinct epith
138 Lineage tracing has highlighted the existence of bipoten
139 Based on
lineage tracing,
ICC-DMP and ICC-SMP each arose from LRI
140 Lineage tracing identified intrinsic recruitment of Scx-
141 Lineage tracing identifies descendants of renin-expressi
142 To address this issue, we used
lineage tracing in a mouse incisor model and identified
143 By
lineage tracing in dorsal skin, we verify that Tcf3-expr
144 Lineage tracing in healthy adult mice revealed that PAX7
145 Lineage tracing in Helicobacter-infected Slfn4 reporter
146 Using
lineage tracing in Lgr5-EGFP-CreERT2/Rosa26-Tomato and L
147 Genetic
lineage tracing in mice indicates that gastrin expressio
148 the fetal testis of humans and rodents, and
lineage tracing in mice shows that they develop into ALC
149 By
lineage tracing in mice, we have shown recently that clu
150 Furthermore,
lineage tracing in postnatal and adult glands provides t
151 etions of the Notch effector RBP-Jkappa with
lineage tracing in Presenilin-deficient endocrine progen
152 ion of stem cell-derived clones using sparse
lineage tracing in the regenerating mouse olfactory epit
153 is question using micro-computed tomography,
lineage tracing in three amniote clades, and RNA-sequenc
154 lines that allow live imaging of MCs and by
lineage tracing in vivo To cover cranial vessels, MCs de
155 enetic techniques, such as cell ablation and
lineage-tracing,
in combination with cell-type-specific
156 Examining the ALPM using
lineage tracing indicated that in Cyp26-deficient embryo
157 Genetic
lineage tracing indicated that stromal cells blocking th
158 s of pancreatic ductal adenocarcinoma, where
lineage tracing indicates that Cytokeratin-Synaptophysin
159 Lineage tracing indicates that the ectopic astrocytes or
160 , IPMNs and PDAC expressed the duct-specific
lineage tracing marker yellow fluorescent protein.
161 oped a flow cytometry-based, high resolution
lineage tracing method and 3D culture system to analyse
162 Here we present CRISPR-UMI, a single-cell
lineage-tracing methodology for pooled screening to acco
163 Recent work using genetic
lineage tracing methods have upended classical ideas abo
164 ges unambiguously other than labor-intensive
lineage-tracing methods.
165 Lineage-tracing mice demonstrate that cells forming HO b
166 We then showed in
lineage-tracing mice that AAV6 vector-mediated in vivo h
167 Using an irreversible
lineage-tracing model, we identify a definitive hematopo
168 In this study, we use genetic
lineage-tracing models and adoptive transfer protocols t
169 vascular-cell-specific and pericyte-specific
lineage-tracing models to trace the fate of perivascular
170 post-Aire MHCII(lo) subset as identified by
lineage-tracing models.
171 Using
lineage tracing,
murine models of heart calcification an
172 Here we used clonal
lineage tracing of active radial glia-like neural stem c
173 Here, we complete the
lineage tracing of all embryonic Hb9(+) neurons (to eigh
174 tiation program of basal cells, we conducted
lineage tracing of basal cells using a K14-CreER;mTmG mo
175 We used single-cell sequencing and genetic
lineage tracing of c-kit(+) cells to determine whether v
176 Lineage tracing of endothelial cells using VE-cadherin(C
177 Here we show that
lineage tracing of Gdf5-expressing joint interzone cells
178 Here, we performed clonal multicolor
lineage tracing of skeletal muscle stem cells (MuSCs) to
179 nal subsets of skeletal cell types, and that
lineage tracing of Wnt-responding cells (WRCs) using the
180 ed sustained clonogenic growth in vitro, and
lineage-tracing of Prox1(+) cells revealed long-lived cl
181 re, we used Cre-recombination of conditional
lineage tracing,
oncogene, and tumor suppressor alleles
182 METHODS AND Using genetic
lineage tracing or bone marrow transplant, we found no e
183 es the investigator to perform either double
lineage tracing or cell lineage tracing combined with ge
184 Lineage tracing revealed scant contribution of pre-exist
185 Here, cell
lineage tracing revealed that cells in which beta-cateni
186 Expression studies and genetic
lineage tracing revealed that Tbx18 is expressed in rena
187 In vivo
lineage tracing revealed that the gene transfer of SeV-G
188 Genetic in vivo
lineage tracing revealed that the Krt15 promoter marks a
189 Genetic cell
lineage tracing revealed that the MesP1+ mesoderm gives
190 Genetic
lineage tracing reveals extensive endothelial plasticity
191 Lineage tracing reveals the former are exclusively Purki
192 hair stem cell marker, keratin 15 (K15), and
lineage tracing show that these K15-derived cells can co
193 Lineage tracing shows that new beta cells are generated
194 tes such repair, we applied a combination of
lineage tracing,
single-cell RNA sequencing, and marker
195 We used genetic
lineage tracing,
single-cell RNA sequencing, and organoi
196 We then applied genetic
lineage tracing,
specific-fluorescent reporter genes, im
197 these dedifferentiating cells using several
lineage-tracing strains and single-cell mRNA-seq, and we
198 Wnt reporter and
lineage-tracing strains of mice have been employed to cr
199 Using elegant
lineage tracing strategies and genetic reporter mouse mo
200 We use multiple models and
lineage tracing strategies to show that this squamous-co
201 Using 2 independent
lineage-tracing strategies in murine models, we show tha
202 Moreover, using a
lineage tracing strategy, we provide evidence that high
203 Here we use a
lineage-tracing strategy optimal for adipocytes to provi
204 Here, we have employed a
lineage-tracing strategy that uses a tamoxifen-dependent
205 Here, using a BAC-CreERT-dependent genetic
lineage-tracing strategy, we determined that a subpopula
206 Employing a p63(CreERT2)-based
lineage-tracing strategy, we identified a unipotent fate
207 Lineage tracing studies confirmed that the metaplasia de
208 Cell
lineage tracing studies demonstrate that class I and cla
209 Lineage tracing studies demonstrated that the original G
210 More recent genetic
lineage tracing studies have shown that VSMC phenotypic
211 Lineage tracing studies performed with conditional trans
212 the development of biliary fibrosis, recent
lineage tracing studies suggest that their contribution
213 Previous
lineage tracing studies using MesP1(Cre) and Rosa26lacZ(
214 Lineage tracing studies using Mesp1(Cre) and T-Cre drive
215 Based on transplantation and
lineage tracing studies, a hierarchy of stem and progeni
216 minal and basal pathways, together with cell
lineage tracing studies, postulates the origin of molecu
217 ciled with recent results of c-kit(pos) cell
lineage tracing studies.
218 l types can complicate the interpretation of
lineage-tracing studies and has caused controversy in ma
219 Recent
lineage-tracing studies based on inducible genetic label
220 In addition,
lineage-tracing studies demonstrated that B cells do not
221 Recent
lineage-tracing studies documenting that resident macrop
222 While
lineage-tracing studies have defined cellular sources of
223 Recent
lineage-tracing studies have implied the existence of pr
224 Recent
lineage-tracing studies have shown that mature hepatocyt
225 gain-of function, conditional knock out and
lineage-tracing studies in rabbits.
226 Lineage-tracing studies in Wnt3a/beta-catenin signaling
227 Results of SMC-
lineage-tracing studies showed that these effects were p
228 Lineage-tracing studies, histologic characterization, an
229 These data, combined with previous PS
lineage-tracing studies, support a model that epithelial
230 the Ins2 locus and demonstrated with a cell
lineage tracing study that the Ins2 gene is not transcri
231 Here we describe a new genetic
lineage tracing system that incorporates the Dre-rox rec
232 Here, we used a chimeric
lineage tracing system to demonstrate that hepatocytes c
233 Here, we use a cholangiocyte-
lineage tracing system to target p53 loss to biliary epi
234 Here we establish an EMT
lineage-tracing system to monitor this process in mice,
235 Here, by using a
lineage-tracing system, we describe three distinct waves
236 ough a distinct progenitor pre-EE by a novel
lineage-tracing system.
237 generated using cell-specific Cre-dependent
lineage-tracing systems.
238 However, recent investigations using cell
lineage tracing techniques have demonstrated that many,
239 eletion of the Rbpj gene in conjunction with
lineage tracing techniques to delineate the precise func
240 Similarly, in the spinal cord,
lineage-tracing techniques have led to a greater underst
241 These
lineage-tracing techniques have precisely demonstrated t
242 Recent studies using genetic
lineage tracing technology have implicated diverse organ
243 Using
lineage tracing,
temporal single-cell analyses, and chro
244 including their own, that suggested based on
lineage tracing that mural cells are adipogenic, contras
245 Here, we demonstrate by cell
lineage tracing that the gills of a cartilaginous fish,
246 In a genetic
lineage tracing the WT1(CreERT2+/-)Rosa(tdT+/-) mouse mo
247 and robust statistical analyses with in vivo
lineage tracing to define a detailed map of the postnata
248 ysis, cell proliferation assays, and genetic
lineage tracing to define the lineage relations and rest
249 Beattie et al. (2017) use elegant MADM-based
lineage tracing to demonstrate cell-intrinsic and global
250 In this study, we used multicolor
lineage tracing to demonstrate that polyclonal seeding b
251 (2017) and Kohler et al. (2017) use in vivo
lineage tracing to demonstrate that these two possibilit
252 icle by Sekiya and Suzuki, detailing genetic
lineage tracing to determine the origin of cells that fo
253 ncreatic ductal adenocarcinoma (PDAC), using
lineage tracing to examine the evolution of disseminated
254 We next employed inducible
lineage tracing to fate map, through Cre recombinase-med
255 issue of the JCI, Kordes and colleagues use
lineage tracing to follow transplanted rat hepatic stell
256 We used genetic
lineage tracing to identify cells responsible for hepato
257 and tamoxifen-induced Cre recombinase-based
lineage tracing to locate putative NMPs in vivo.
258 Using
lineage tracing to mark cells derived from leucine-rich
259 Here we use genetic
lineage tracing to mark the Nppa(+) or Hey2(+) cardiomyo
260 Here, we use clonal analysis and
lineage tracing to show that caSMCs derive from pericyte
261 olini et al. (2015) perform rigorous in vivo
lineage tracing to show that individual neural crest pre
262 We used multicolor Cre-reporter
lineage tracing to show that most of these neurons arise
263 We employ
lineage tracing to show that these castration-resistant
264 We created an ApjCreER mouse line as a
lineage-tracing tool to map SV-derived vessels onto the
265 . report on their employment of a battery of
lineage-tracing tools to address the developmental origi
266 trovirus-encoded DNA barcodes as unambiguous
lineage-tracing tools to address this question, finding
267 Lineage-tracing,
transcriptome, and chromatin analyses s
268 We used
lineage tracing,
transplantation studies, and parabiosis
269 Lineage tracing using a multi-colored reporter demonstra
270 Finally, genetic cell-
lineage tracing using Kaede photoconversion demonstrates
271 Lineage tracing using MISR2-Cre indicated that the tubul
272 Finally,
lineage tracing using ROSA(mTmG);Wt1(CreER) mice showed
273 Lineage tracing using Rosa-td tomato (Col2-Cre-ERT2) mic
274 Lineage tracing using the Cre-LoxP system reveals select
275 By
lineage tracing using the Wnt-responsive gene Axin2 in m
276 Lineage tracing using ZsGreen(Cdh5-Cre) reporter mice co
277 While
lineage tracings using cyclization recombinase (Cre) rec
278 avelength cones in developing rods, and cell-
lineage tracing validated the genesis of rods from S con
279 This approach makes use of a
lineage-tracing vital stain that is retained through cel
280 flow cytometry, immunostaining, and genetic
lineage tracing,
we demonstrate that the developing hear
281 By
lineage tracing,
we demonstrate that the Tcf3-expressing
282 Using additional prospective
lineage tracing,
we demonstrate that while SHF ventricul
283 2) Using
lineage tracing,
we demonstrated that CACs do form new e
284 Through in vivo
lineage tracing,
we demonstrated the power of this appro
285 in different cardiac populations followed by
lineage tracing,
we determined that NFPs in the second h
286 Using
lineage tracing,
we documented a robust population of td
287 oxed STOP eYFP Apoe(-/-) mice to perform SMC
lineage tracing,
we find that traditional methods for de
288 Using cell
lineage tracing,
we further demonstrate that trunk neura
289 Using cell-
lineage tracing,
we identify a population of GAP43(+) PL
290 With
lineage tracing,
we now provide direct evidence that Sox
291 By employing genetic
lineage tracing,
we provide evidence that in adult mice
292 Using genetic
lineage tracing,
we show that Doublecortin-like kinase-1
293 Using inducible genetic
lineage tracing,
we show that K14(+) ductal cells repres
294 Using sonic hedgehog
lineage tracing,
we show that the third and fourth ventr
295 Using genetic
lineage tracing,
we systematically investigated the role
296 lyses, in utero lentiviral transduction, and
lineage-tracing,
we show that in developing hair buds, S
297 Moreover,
lineage tracing with an Oct4-CreER labeling system demon
298 Lineage tracing with four additional Cre-expressing mous
299 Lineage tracing with Mesp1-Cre mice revealed that Mesp1(
300 This in-vivo
lineage-tracing work demonstrates that luminal cells are