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1 drug actions on ion channel function are not linear.
2 en alkynes to generate a structurally rigid, linear 1,3-diyne linkage has been known for over a centu
3 ircumferential pulmonary vein isolation plus linear ablation of extrapulmonary rotor domains.
4 cy combs can rapidly measure high-resolution linear absorption spectra.
5 eater than dose-proportional, suggesting non-linear accumulation.
6 rfold higher following administration of the linear agents gadodiamide and gadobenate dimeglumine com
7                                              Linear alkyl benzenes (LAB) are global chemicals that ar
8 e sigmoid on a log-log plot is very close to linear, allowing the unknown endogenous concentration to
9 ers a regioselectivity switch, allowing both linear and branched isomers to be prepared with high sel
10         Using the chain-end N3, the obtained linear and brush polymers were connected to functional m
11  We provide examples of learning linear, non-linear and chaotic dynamics, as well as the dynamics of
12 The method can be applied to synthesize both linear and cyclic peptides, as well as peptides composed
13           Results Exposure to varlilumab was linear and dose proportional across dose groups.
14    Postoperative findings were compared with linear and generalized linear mixed-effects regression m
15  pregnancy outcomes and PAM indicators using linear and logistic multivariate models.
16                                 Multivariate linear and logistic regression models were performed to
17                                     Multiple linear and logistic regression models were used to exami
18                                  We used log-linear and nonlinear concentration-response coefficients
19 e as a function of the input pump power, the linear and nonlinear losses, and the coupling factors.
20 brain metabolism were modeled using multiple linear and nonlinear mathematic equations, and the signi
21  plaque score, and periodontal severity with linear and ordinal logistic regression models before and
22                                              Linear and quadratic correlation analyses were used to e
23  BMI in daughters at midlife using quantile, linear, and logistic regression models.
24  different RNA hybridization networks with a linear architecture, and we implemented them in Escheric
25 fc = 1,1'-ferrocenediyl), composed of a near linear arrangement of donor atoms, exhibits a large ener
26 y an external surface, but likely reflects a linear arrangement of regulatory molecules.
27          For detection of HPV types, a Roche Linear Array test was performed.
28                                    An 18-MHz linear array was used to acquire plane-wave data at abso
29        The present study indicates a postive linear association between oral health and mortality.
30 treatment as covariates, revealed a positive linear association between PCSK9 levels and the risk of
31                                           No linear association was observed between maternal B12 lev
32   The mass-transport regime is altered from "linear" at very short time, where the amperometric respo
33 romatic stabilization energy, while extended linear benzannelation results in increased retro-Bergman
34 w a network of spiking neurons can learn non-linear body dynamics using local, online and stable lear
35                   The average ODxRS for fine linear branching calcifications was 29.6, whereas the OD
36 n disease severity and dopamine loss appears linear, but the majority of longitudinal studies point t
37 d method is simple, fast (<12.0min), present linear calibration curves (r(2)=0.995), and relative sta
38 over a few discrete time frames or assumed a linear change.
39            Telomeres, the protective ends of linear chromosomes, shorten throughout an individual's l
40                                A significant linear chronic EC loss was reported after implantation w
41 s and groups of microrobots were moved along linear, circular, and arbitrary 2D trajectories.
42 his method to be used for fingerprinting and linear combination analysis of known XANES reference com
43                                              Linear combination fitting of extended X-ray absorption
44 st, we modeled the expression of a gene as a linear combination of the expression of TFs.
45 ementary to the physical potentials, where a linear combination of the profile score with the FoldX p
46      Furthermore, the inherent assumption of linear combinations of decays in global analysis means t
47                                              Linear combinations of whole muscle-tendon force and the
48 es and employed a curve fitting approach for linear comparison of cell types and introduced a novel s
49 -FET was tested for NADH detection showing a linear concentration range 1aM to 1nM and a low detectio
50                                            A linear concentration range was obtained from 1.0x10(-8)
51 es are observed when going from isomers with linear connectivity of the fused benzene rings to those
52                                  Through non-linear conversion of locomotor activity to "Locomotor In
53    For samples heated with hot air, the best linear correlation achieved was R(2)=0.90 and by microwa
54 ide linear range 0.03-600 ng/mL) with a good linear correlation coefficient (0.9999), a high detectio
55 of the liquid chromatography method, where a linear correlation of more than 0.99 was achieved.
56 rocedure was applied to the abdomen phantom, linear correlation of phantom and patient Hounsfield uni
57                      In-vitro tests showed a linear correlation of R(2)=0.998 between sensor values a
58                       For both parameters, a linear correlation was found between the measured values
59                     We are able to use these linear correlations to improve reaction enantioselectivi
60 procedure consisting of fissure opening with linear cutting staplers buttressed with paired alginate
61 nd recent computational work suggests that a linear decoder can approximate marginalization by taking
62  a challenging task because of noncompatible linear detection ranges or strong signal overlap that su
63 er the analytical parameters optimization, a linear detection response from 0.01pg/mL to 2pg/mL, a li
64  with a height 10 mm or greater or a longest linear diameter greater than 16 mm or a height greater t
65            Using x-ray magnetic circular and linear dichroism techniques, we demonstrate a collinear
66 ysis, and computational approaches including linear discriminant analysis (LDA) and sparse canonical
67          A machine-learning algorithm called linear discriminant analysis (LDA) was trained by using
68  measurements have shown an unusually robust linear dispersion (up to [Formula: see text]2 eV) with m
69  two-dimensional electronic bands, each with linear dispersion and the additional Berry phase predict
70  energy, suggesting the emergence of the MDF linear dispersion in the AG.
71 m its two-dimensional (2D) structure, with a linear dispersion of the electronic states at the corner
72                            However, one-site linear DNA is a poor substrate, supporting a mechanism w
73  chloroplast genome that is composed only of linear DNA molecules is unprecedented among eukaryotes,
74 n increased risk of all-cause mortality in a linear dose-response meta-analysis.
75 onensis Each strain encodes a 9.8- to 9.9-kb linear double-stranded DNA (dsDNA) genome with large inv
76                                   Due to the linear double-stranded DNA nature of the adenovirus geno
77 oup developed higher IgG responses against a linear epitope in the gp120 C1 region of the HIV-1 envel
78 s well as an intact protein bearing multiple linear epitopes.
79                              Here we pattern linear fibronectin features to mimic fibrillar ECM and e
80         Arguments can certainly be made that linear-field particle acceleration in free space is very
81 hat VWF is first converted from a compact to linear form by flow, and is subsequently activated to bi
82 tail peptide via cation-pi interactions, but linear free energy trends suggest they do not contribute
83                             The response was linear from 0.1mM to 1.0mM.
84 O2 response of the fabricated electrodes was linear from 2.5 x 10(-3) to 6.5 mM with a sensitivity of
85 regions where the dynamics are approximately linear from those that are strongly nonlinear.The huge a
86 mulation frequency; average [Ca(2+) ]i was a linear function of Ca entry per unit time.
87 samples with 13 and 25 mol% cholesterol is a linear function of the heat capacity measured by differe
88                                      The non-linear gain was typically 10-30 dB and was broad-band ra
89 at chromosomal looping, bypassing 1524 kb of linear genome, connects Auts2 to the Caln1 gene locus un
90            Herein, we combined the stringent linear geometric interaction constraints of halogen bond
91 LYP, CASPT2, and CCSD(T) methods all predict linear geometries for both the anions and the neutral ra
92 e in rural Gambia had a very small effect on linear growth and did not reduce morbidity compared to u
93 quadratically initially, followed by further linear growth and eventual gradual saturation.
94               Our studies demonstrate that a linear hexazole-bearing intermediate of TbtA is a substr
95                    The calibration curve was linear in the concentration ranges of 0.8-400mugL(-1) (R
96                            Both methods were linear in the range of 0-100mg EDTA equivalents/L.
97  the suppression of the Knight shift and the linear-in-T spin echo decay that increases with doping.
98                                The rapid non-linear increase in heat-related morbidity is difficult t
99 the testes were significantly elevated and a linear increasing trend of 15-HETE concentrations was de
100                 These data also replicated a linear inequality-ambivalence relationship.
101 rimotor noise from multiple sources, and non-linear input transformations, for example thresholds or
102                                      A short-linear interaction motif between residues 337-343 of AKA
103                                              Linear interaction NH3(+) - carbonyl represents an inter
104 reas are extremely sensitive to changing non-linear interactions between individual components caused
105                             An electrostatic linear ion trap (ELIT) has been configured to allow for
106 c order in a Fourier transform electrostatic linear ion trap (ELIT) mass spectrometer.
107 ent discrete model and use the method of non-linear least squares to estimate the age-specific annual
108                     Patients with or without linear lesions did not differ significantly with respect
109 ed-coil 1 domain that impedes the binding of linear (M1-linked) di-ubiquitin to its coiled-coil 2-leu
110 te exhibit the abrupt appearance of positive linear magnetostriction, leading to a trigonal distortio
111 h 12 (mean of months 6 and 12), which used a linear mixed effects model for repeated measures and rep
112 actors for RTIs were assessed by generalized linear mixed method regression modeling.
113  model (VST) outperform the voom-transformed linear mixed model (voom).
114 t), and the variance stabilizing transformed linear mixed model (VST) outperform the voom-transformed
115 ea under the curve, logistic regression, and linear mixed model analyses, was tested.
116 ses the correlation between residuals of the linear mixed model to estimate the null distribution of
117 ; P < .001) with ferrous sulfate (based on a linear mixed model).
118  BMI and waist circumference over time using linear mixed modeling with random effects.
119                                              Linear mixed models and generalized estimating equations
120  stressors and their interactions, we fitted linear mixed models controlling for relatedness for the
121                       We present appropriate linear mixed models for all designs and develop effect s
122                        Data were analyzed by linear mixed models or generalized linear mixed models,
123                   Specifically, phylogenetic linear mixed models show that the formation of families
124            We used multivariable generalized linear mixed models to evaluate the association of the P
125                                  Generalized linear mixed models were used to take account of repeate
126  and executive functioning test scores using linear mixed models, adjusted for sex and education, and
127                                        Using linear mixed models, we examined associations of trauma/
128                                        Using linear mixed models, we found that increasing residentia
129 alyzed by linear mixed models or generalized linear mixed models, which controlled for fiber intake,
130 d participant demographic characteristics in linear mixed models.
131  change in modified Rodnan skin score, using linear mixed models.
132  Multiple relationships were tested by using linear mixed-effects modeling.
133 and e' velocity using multivariable-adjusted linear mixed-effects models (to account for relatedness
134 Disease Risk Score-associated proteins using linear mixed-effects models in 2 population-based cohort
135 gs were compared with linear and generalized linear mixed-effects regression models.
136                                      We used linear mixed-effects regression to model the relation be
137 CPPCO-Sc skeleton but also to compare to the linear mode observed in the precursor.
138              Applying a standard generalized linear model analysis approach, our results indicate tha
139              LINSIGHT combines a generalized linear model for functional genomic data with a probabil
140             We developed a new multivariable linear model for GFR using statistical regression analys
141  Kallisto TPM data gives the best fit to the linear model studied.
142 cific means were compared by using a general linear model with false discovery rate control for multi
143 ctivation of study centers using generalized linear model.
144 ive fitness ratios and fitting a generalized linear model.
145 d assessed differences between conditions by linear modeling of the data.
146 Comparison of teeth and implants via general linear models based on orthogonal polynomials showed sim
147 ssociations were estimated using Poisson log-linear models controlling for continuous air temperature
148                             A consequence of linear models is that faster translation of a given mRNA
149      Intention-to-treat analysis using mixed linear models showed that PBT was noninferior to FBT on
150                                Mixed-effects linear models were tested with visual field mean deviati
151                                          Log-linear models were used to estimate prevalence ratios (P
152                                  Generalized linear models were used to predict the spiking activity
153                                              Linear models with generalized estimating equations were
154                      In adjusted generalized linear models, in addition to MELD (P < .001), factors i
155 rate that the frequency of a small number of linear motifs three amino acids in length can accurately
156 realization of the importance of angular and linear movement-integration in generating spatial maps.
157 creased while expression of their associated linear mRNAs concomitantly decreased.
158                                        While linear multichannel pipets enable many established assay
159                                              Linear multivariate regression showed that successful ag
160 s treated with DTT, and did not occur with a linear (non-disulfide-bonded) peptide, or when the doubl
161              We provide examples of learning linear, non-linear and chaotic dynamics, as well as the
162 s of less than 600 kilometres per second and linear offsets of less than 100 kiloparsecs.
163 d breath of the complete series of saturated linear omega-hydroxyalkanoic acids, omega-oxoalkanoic ac
164 ne of these approaches have yet demonstrated linear optical isolation with ideal characteristics over
165 re difficult to identify unambiguously using linear optical spectroscopy methods.
166 e are multiple, degenerate, interchangeable, linear or 3D hydrophobic stretches that become available
167 sisting of two aromatic rings connected by a linear or a cyclic spacer.
168 -, partially- and per-fluorinated aliphatic (linear or branched at the alpha-carbon) and aromatic est
169 ltrathin FeRh/MgO bilayers exhibits distinct linear or nonlinear behavior across the AFM to FM metama
170 across time from 42% in 1997 to 38% in 2012 (linear P-trend < 0.0001).
171 007 (35-33%) and then sharply by 2012 (18%) (linear P-trend < 0.0001).
172 the sequence of RAM is poorly conserved, the linear patterning of oppositely charged residues shows m
173 u)2-COOtBu, the longest to be solved for any linear peptoid, revealed a PPI helix of great regularity
174 Furthermore, phantom images reveal analogous linear pH behavior.
175 ntrast to previous work, coherence-based non-linear phase inversion processing was used to reject tis
176  for confounding factors using a generalized linear Poisson model, in high-risk cluster the prevalenc
177  our most conservative simulation), variable linear polarization of a prompt optical flash that accom
178  the system as consisting of three different linear polymers.
179                              Specifically, a linear precursor copolymer of styrene and 4-(diphenylpho
180                                              Linear probability models with a difference-in-differenc
181 th a thiolase that highly prefers unbranched linear products.
182 od can efficiently implement data-driven non-linear projection and incorporate prior biological knowl
183 on-based radiation-sensitivity index and the linear quadratic model to derive the genomic-adjusted ra
184 alysis of variance was performed to evaluate linear, quadratic and interaction effects between fermen
185 ns as well as neutral loss scans in a single linear quadrupole ion trap have recently been described.
186 t of single analyzer neutral loss scans in a linear quadrupole ion trap using orthogonal double reson
187  on single analyzer precursor ion scans in a linear quadrupole ion trap, we now report the developmen
188  The proposed CLIA assay demonstrated a wide linear range 0.03-600 ng/mL) with a good linear correlat
189 ows the lowest detection of 1ngml(-1) with a linear range 100ng to 1microg due to the increased react
190 changes in absorption from 540 to 580nm; the linear range and the limit of detection are 30-1000micro
191  sensitivity of 26.2nm/microM in addition to linear range from 0 to 3microM with an invincible LOD va
192  used for the determination of NO2(-) with a linear range from 0.1-1600microm and a detection limit o
193 TCNE photoelectrochemical sensor presented a linear range from 0.6 to 250mumolL(-1), sensitivity of 0
194 ucleotides specifically and sensitively in a linear range from 50.0fM to 1.0nM with a detection limit
195 ts non-sandwich counterpart, which yielded a linear range of 0.05-0.40microgmL(-1), with a detection
196  proposed method could detect the CEA with a linear range of 0.05-0.50microgmL(-1) and a detection li
197 l performances in cancer cell detection with linear range of 1x10(2) to 1x10(6)cellsml(-1), detection
198         Using a consumer digital camera, the linear range of the detector response ranged from 0 to 6
199                        The results shown the linear range of the sensor was 40.0-1100.0 femtomolar an
200 n outstanding analytical performance, with a linear range that spans from 1microM to 10mM and limit o
201 -glucose microbiosensor revealed an extended linear range, high sensitivity and selectivity, fast res
202 k, deviated from the predictions for optimal linear readout of a population with information-limiting
203 rrelated with the quercetin concentration by linear regression (molar extinction coefficient 23.2 (+/
204 ve binominal regression (plaque number), and linear regression (plaque size), and compared between ra
205                     Regularized multivariate linear regression accurately quantifies individual allel
206 esults from age- and race/ethnicity-adjusted linear regression analyses indicated modest, but statist
207                   Results from multivariable linear regression analyses indicated that serum concentr
208                  Univariate and multivariate linear regression analyses were performed to determine t
209 -media thickness (cCIMT) using multivariable linear regression analysis among 1554 African Americans
210                       Pearson's correlation, linear regression analysis for clinical outcome paramete
211                              Correlation and linear regression analysis reveal a strong association b
212                             We used multiple linear regression analysis to compare SMC with GES, adju
213                                              Linear regression analysis was performed to identify tre
214 lity and gait difficulty motor PD subtype in linear regression analysis, but staging of alpha-synucle
215 HDI] and Gross Domestic Product [GDP]) using linear regression analysis.
216  in the phantom experiment by using multiple linear regression analysis.
217  the eQTLs identified by QRank but missed by linear regression are associated with greater enrichment
218                                              Linear regression assessed the association between imagi
219                                              Linear regression indicates agreement between the concen
220                                            A linear regression model incorporating indices for the PD
221         In addition, a two-step hierarchical linear regression model showed that significant predicto
222               We constructed a mixed-effects linear regression model with the individual physician as
223 is and residual analysis based on a multiple linear regression model.
224 recorded, transcribed, and analyzed by using linear regression modeling for group differences.
225                                     Multiple linear regression models adjusted for potential confound
226                                              Linear regression models and the t-test were employed to
227 ational diabetes mellitus (GDM), and we used linear regression models to estimate associations with f
228 , cell types, and covariates, we used robust linear regression models to examine associations of pren
229                                       Single linear regression models were built with data compiled f
230 52 SNPs to all phenotypes using logistic and linear regression models.
231 metry and function by multivariable-adjusted linear regression models.
232                                              Linear regression of acute individual measures with cont
233                                 Multivariate linear regression tested the association of ante mortem
234                                      We used linear regression to determine change in cognitive perfo
235                                      We used linear regression to test intervention effects on use of
236                                              Linear regression was used to control for state, age, se
237                                Multivariable linear regression was used to determine the association
238                    Multivariable Poisson log-linear regression was used to estimate adjusted risk rat
239                                              Linear regression was used to evaluate how levels of cor
240 atic PDFF accuracy were assessed by means of linear regression with the respective reference standard
241 -phenotypes were analyzed using logistic and linear regression, and Cox proportional hazards models.
242 ifying mean effects on gene expression using linear regression, evidence suggests that genetic variat
243 esults were compared using Cohen's kappa and linear regression, respectively.
244 tants (k values), which were obtained by non-linear regression, showed that the degradation rate of d
245 ect to a sum-to-zero constraint in penalized linear regression, where the correspondence between nonz
246 after TAVR were examined using multivariable linear regression, with adjustment for baseline health s
247  be tissue specific than eQTLs identified by linear regression.
248 trol for risk factors and copollutants using linear regression.
249          We studied the relation VA-QoL with linear regression.
250                                          Log-linear regressions were adjusted for a priori selected c
251 n positions but rather are caused by the non-linear relationship between binding affinity and binding
252 ous asymmetric configurations, we revealed a linear relationship between the magnitude of cooperative
253                         One species showed a linear relationship between the methods.
254 spawning period after high tide to produce a linear relationship.
255                         We found significant linear relationships between camera-NDVI and leaf chloro
256      Motor output also always includes a non-linear remnant resulting from random sensorimotor noise
257 rimotor noise is required to explain the non-linear remnant.
258 vity and sensitivity towards NSE, produced a linear response in the concentration range from 0.01 to
259                             The sensor has a linear response in the range of 20-160microgL(-1) with a
260 rease and/or amplification highlight the non-linear response to sea-level variations, with the potent
261 aining C14-C20 fatty acids (FAs) showed good linear response.
262 ed by the excitonic state, and then a second linear-response TDDFT calculation is used to determine t
263 s based on a two-step calculation in which a linear-response TDDFT calculation is used to generate or
264                              We identified a linear risk of incident MI (0.8% annually), with ST-segm
265  was synthesized in 23 steps for the longest linear route, with a 1.7% overall yield from d-cellobios
266 ectively assess the quality of postoperative linear scars.
267 d to transmission within a level (e.g., in a linear section).
268 s prepared from simple building blocks via a linear sequence of six chemical reactions in five flow r
269 st current non-PCR detection methods rely on linear signal amplification, which hinders the detection
270  We propose that these contigs correspond to linear single-stranded DNA molecules that fold onto them
271 stic relaxation model, for example, standard linear solid (SLS) or power-law rheology (PLR), best sui
272                         Sylgard-184 showed a linear sorption and outgassing behavior with no-hysteres
273 ations and were fit sufficiently well with a linear sorption model.
274 t fly Drosophila melanogaster results in the linear sorting of a set of diverse isogenic female lines
275 account for relatedness among subjects) with linear splines (spline 1: ESI </=3.7 g/day, spline 2: ES
276 isson regression with confounder adjustment; linear splines were used to account for nonlinearity.Mat
277 l) in a microfluidic channel that produced a linear SS gradient over a 20mm field ranging from 0-16 d
278 f macrolide natural products in as few as 15 linear steps (21 total) with an overall yield of 4.6%.
279 reptogramin antibiotics that proceeds in 6-8 linear steps from simple chemical building blocks.
280 mentum-space mapping of the second-order non-linear structure factor is the source of this contrast a
281                                   Sa15 forms linear structures in meiotic prophase nuclei to which Zh
282 lly measured with BOLD imaging in humans, as linear sums of groups of neurons (channels) tuned for vi
283 for 18 h versus the absorbed dose followed a linear survival curve with alpha = 0.51 +/- 0.05 Gy(-1)
284 patially bandpass early filtering means that linear systems techniques, such as deriving channel sens
285                     However, one-dimensional linear techniques cannot distinguish the sources of reso
286 ercise performance and composite outcome was linear; thus, no reliable cutoff point could be identifi
287 m, which can then be efficiently solved with linear time and space complexity.
288 Our findings revise prevailing paradigms for linear, time-invariant resonant systems, challenging the
289 rm that the former is caused by a 400 K non-linear-transport-driven instability and the latter is ca
290                                    The GLASS linear trend and interannual variability were almost 4.5
291 s, where we found the surprising effect that linear two filament connections act as transistor-like,
292                                          The linear ubiquitin chain assembly complex, LUBAC, is the o
293 ase in the E3 ligase HOIP, which synthesizes linear ubiquitin chains.
294 1)-linked polyubiquitin (also referred to as linear ubiquitin).
295                                              Linear ubiquitination is a key posttranslational modific
296 n a male fetus with IP, leading to defective linear ubiquitination.
297              Nc-bacterial evenness displayed linear, unimodal, or no response to algal pigment levels
298 tion of one of these V2 Abs revealed how the linear V2 epitope could be engaged, despite the lack of
299 ed two types of latitudinal patterns, either linear, when related to body size, or parabolic in shape
300 Bronsted plot of ln(kMS-CPET) vs ln(Keq) was linear with a slope of 0.46.

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