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1 ct hyaladherins (aggrecan G1-NITEGE(373) and link proteins).
2 ntracellular scaffolding partner of this tip-link protein.
3 sulfate proteoglycans (CSPGs), aggrecan and link protein.
4 achinery, including the MET channels and tip-link proteins.
5 ands making multiple contacts with the cross-linked protein.
6 ar cyclization and a high yield of the cross-linked protein.
7 mor cells as a glycosyl-phosphatidylinositol-linked protein.
8 ross-linking sites are adjacent in the cross-linked protein.
9 dimers in the membrane by analysis of cross-linked proteins.
10 conjugation to visualize and identify cross-linked proteins.
11 oponin and exposed to UV light to form cross-linked proteins.
12 implicated in the processing of other ataxia-linked proteins.
13 keys, give rise to efficiently processed GPI-linked proteins.
14 g ortholog partners in pairs of functionally linked proteins.
15 luble structure composed of covalently cross-linked proteins.
16 ization, and interaction with itself and ALS-linked proteins.
17 ormed after enzymatic digestion of the cross-linked proteins.
18 raplakin, as a model actin-microtubule cross-linking protein.
19 hat differ in expression of this actin cross-linking protein.
20 ich is progressively stabilized by the cross-linking proteins.
21 V) and vascular stiffness, in part via cross-linking proteins.
22 otors and static forces from non-motor cross-linking proteins.
23 of plasma membrane-actin cytoskeleton cross-linking proteins.
24 band of cortical nodes and bundled by cross-linking proteins.
28 inin alpha1, and hyaluronan and proteoglycan link protein 1 (Hapl1) production as well as proliferati
29 , we report that hyaluronan and proteoglycan link protein 1 (HAPLN1) is produced in bone marrow strom
30 oglycan versican/hyaluronan and proteoglycan link protein 1 rich myxoid matrix, which is in direct co
35 inantly of the proteoglycan versican and its linking protein, a vertebrate hyaluronan and proteoglyca
36 ce of unbinding and unfolding of actin cross-linking proteins (ACPs) in the dynamic properties of the
37 aggregation of glycosylphosphatidylinositol-linked proteins activates Src-family kinases, the activa
38 n moieties are substituted for the thioester-linked protein acyl-modifications through a sequence of
40 e findings, we propose that 2 mechanisms may link protein aggregation and cardiac function: oligomer-
42 olated raft fractions were enriched in a GPI-linked protein, alkaline phosphatase, and were poor in N
43 ciated proteins, isolation of the covalently linked proteins allows their identity to be assigned.
44 king is modulated by the Parkinson's disease-linked protein alpha-synuclein, but the contribution of
45 chizosaccharomyces pombe, in which the cross-linking protein alpha-actinin SpAin1 bundles the actin f
46 tin bundling by interacting with actin-cross-linking protein alpha-actinin-1 and increasing its affin
47 s, regulation of the homodimeric actin cross-linking protein alpha-actinin-4 (ACTN4) during cell migr
49 egment, reminiscent of the Parkinson disease-linked protein, alpha-synuclein, which we show shares a
50 l peptide (LPP) is a proteolytic fragment of link protein, an important cross-linker and stabilizer o
51 We present a robust strategy to covalently link proteins and DNA using HUH-endonuclease domains as
52 M, integrates static and time series data to link proteins and the pathways they regulate in these ne
53 elin (HJV) is a glycosylphosphatidylinositol-linked protein and binds both bone morphogenic proteins
56 e that HJV is a glycosylphosphatidylinositol-linked protein and undergoes a partial autocatalytic cle
57 family of extracellular matrix receptors and linked proteins and discuss the evidence supporting thes
59 ope is assembled from transglutaminase cross-linked proteins and lipids in the outermost epidermal la
60 nding this method to the separation of lipid-linked proteins and transmembrane proteins while minimiz
61 l genomic analysis, we identify functionally linked proteins and verify their interaction in vitro by
63 aralog-specific behaviors of different cross-linking proteins and identify a zone of optimal actin-bi
65 tween the density of myosin motors and cross-linking proteins and the rigidity, initial orientation,
66 s a ubiquitously expressed enzyme that cross-links proteins and its overexpression, linked to a drug
68 of receptors, signal transducing kinases and linking proteins, and is responsible for the motile resp
69 ting of actin filaments, alpha-actinin cross-linking proteins, and non-muscle myosin IIA mini-filamen
70 aninum produces a family of small, disulfide-linked protein anticoagulants (75-84 amino acid residues
71 n the premise that hair cell stereocilia tip-link proteins are closely coupled with MET, these result
73 ific toxicity, despite the fact that disease-linked proteins are generally ubiquitously expressed.
77 of actin filaments, myosin motors, and cross-linking proteins at biologically relevant time and lengt
78 ding with elevated expression of actin-cross-linking proteins at the neuronal growth cone, namely pho
79 n the central hydrophobic core and the cross-linked protein body periphery, respectively, but little
80 tructures contains actin filaments and cross-linking proteins, but the role of cross-linking proteins
83 pha-actinin-4 (Actn4), a dynamic actin cross-linking protein, cause proteinuric disease in humans and
84 to the carboxyl terminus of stereocilia tip-link protein CDH23 +68 (cadherin 23 with expressed exon
85 otein interaction for CNGA3 and a second tip-link protein, CDH23 +68, further suggests possible assoc
92 ubstrate pairs into stable, covalently cross-linked protein complexes, thereby facilitating their sub
94 ction of stable secondary and tertiary amine-linked protein conjugates without affecting the structur
97 riggered by neuronal production of cartilage link protein Crtl1 (Hapln1), which is up-regulated in th
99 of caveolin-3 and filamin (an F-actin cross-linking protein), decreased phosphorylation of caveolin-
100 vel regulators of endoplasmic reticulum (ER)-linked protein degradation and ER function, we determine
101 f proteomic pathway analysis to functionally link proteins differentially expressed in bone and skin
103 ne the rate of cross-link reversal for cross-linked protein-DNA complexes from yeast cell lysate.
105 ases that bind and cleave the target through linked protein domains (e.g. TALENs and zinc-finger nucl
106 evation of hydrostatic pressure, the fission-linked protein, Drp-1 was translocated from the cytosol
112 closely related to the membrane-cytoskeleton linking proteins Ezrin, Radixin, and Moesin, and localiz
113 s (potentially containing new members of the link protein family), in which other chondroitin sulfate
114 Recent studies showed that the actin cross-linking protein, fascin, undergoes rapid cycling between
116 investigate the behaviors of two actin cross-linking proteins, fascin and alpha-actinin, during the f
117 ll GTPase Rab1A as well as the F-actin cross-linking protein filamin (actin-binding protein 120, abp1
119 esis that interactions between F-actin cross-linking protein filamin A and caveolin-1 facilitate the
120 entified the non-muscle actin filament cross-linking protein filamin A as a novel Gag binding partner
122 so interacted with the mammalian actin cross-linking protein filamin in the yeast two-hybrid assay th
125 ctivation), whereas binding of another actin-linking protein, filamin, to the integrin beta CTs negat
126 ssociated protein AFAP-110 is an actin cross-linking protein first identified as a substrate of the v
130 ly become appreciated as a modification that links protein function to cellular oxidative status.
131 ed to the identification of 50 potential Trx-linked proteins functional in 12 processes: photorespira
134 olyprenol reductase with a crucial role in N-linked protein glycosylation and pinpoint SRD5A3 mutatio
136 ome underscores the importance of asparagine-linked protein glycosylation for proper functioning of t
137 Our findings underscore the importance of N-linked protein glycosylation for proper functioning of t
138 framework for understanding the process of N-linked protein glycosylation in Bacteria and for devisin
156 since the discovery of asparagine-linked (N-linked) protein glycosylation pathways in bacteria, majo
157 llapse radially due to the activity of cross-linking proteins, hence producing conical-shaped filamen
158 oxyl terminus of protocadherin 15 CD3, a tip link protein implicated in mechanosensory transduction.
160 some mothers develop antibodies against a Y-linked protein important in male brain development, and
162 levels coding for aggrecan, collagen II, and link protein in chondrocytes exposed to endoplasmic reti
163 xamined for the first time the expression of link proteins in human brain and malignant gliomas.
164 three-dimensional matrixes composed of cross-linked protein in cellular and microfluidic environments
165 s that females have, yet the expression of X-linked proteins in males is the same because of a sex-sp
166 proteomic approaches to identify soluble Trx-linked proteins in mitochondria isolated from photosynth
168 he role of typical Rho GTPases and other Rho-linked proteins in synaptic plasticity and cognitive fun
171 f cellular localization of known actin cross-linking proteins in mouse melanoma B16F1 cells revealed
172 aracterized actin-filament bundling or cross-linking proteins in plants and each is encoded by a mult
173 ross-linking proteins, but the role of cross-linking proteins in the initial steps of structure forma
174 of filamin A (FLNa), an actin filament cross-linking protein, in wound contraction and maintenance of
177 oposed that the partial proteolysis of cross-linked proteins into smaller oligopeptides constitutes a
178 d accumulation of polyubiquitinated (K48/K63-linked) proteins into juxtanuclear aggresomes, without a
179 ncrease the expression of one of these cross-linked proteins, involucrin, and that this effect can be
180 identified filamin A (FLNa), an actin-cross-linking protein involved in cell movement, as a bona fid
181 rotein that regulates the Arp2/3 complex and links proteins involved in endocytosis to the actin cyto
183 e; subsequently, DNA together with all cross-linked proteins is isolated by centrifugation under dena
184 osylated, glycosylphosphatidylinositol (GPI)-linked protein, is expressed preferentially by myofiber
186 alpha-actinin and palladin, two actin-cross-linking proteins, is essential for proper bidirectional
189 und to participate in multiprotein complexes linking protein kinase A to the activation of phosphodie
192 that alpha actinin 4 (ACTN4), an actin-cross-linking protein known to coordinate cytoskeletal organiz
195 There is abundant epidemiological evidence linking protein malnutrition to impaired vaccine efficac
197 or a d-amino acid polymer antigen in a cross-linked protein matrix was shown to be sufficient to prod
198 ymer bundles, which also suggests that cross-linking proteins may contribute to the regulation of the
199 tolithographic method for constructing cross-linked protein microstructures, permits one to compartme
200 ggest that CHOP is a fundamental factor that links protein misfolding in the ER to oxidative stress a
205 ases the activity and function of plasticity-linked protein networks in the amygdala that regulate th
206 it is possible that STIM1 represents a nexus linking protein O-GlcNAcylation with Ca(2+)-mediated tra
207 interactions between myosin and actin cross-linking proteins observed in cellular mechanosensation,
211 s lacking glycosylphosphatidylinositol (GPI)-linked proteins on their surface (GPI(neg)) exist alongs
214 lagen biosynthesis as well as collagen cross-linking protein, P4HA1 and PLOD2 were observed along wit
216 t-resistant membrane domains, into which GPI-linked proteins partition, are enriched in cholesterol a
218 immune signaling module downstream of PRRs, linking protein phosphorylation cascades to metabolic re
219 orporation of a glycosylphosphatidylinositol-linked protein (placental alkaline phosphatase) occurred
220 volutionarily conserved actin bundling/cross-linking protein plastin is instrumental for the generati
222 that Ubc13, an E2 enzyme that catalyzes K63-linked protein polyubiquitination, is largely dispensabl
223 Uev1a, specifically mediates lysine 63 (K63)-linked protein polyubiquitylation, a process that does n
224 identification and characterization of cross-linked proteins presents a significant analytical challe
225 repeat containing 2 (XIRP2), an actin-cross-linking protein previously reported to be specifically e
228 ein-protein interaction between HCN1 and tip-link protein protocadherin 15 CD3, a protein-protein int
229 coupling between HCN1 and stereociliary tip-link protein protocadherin 15 has been described for a t
232 ied by alkaline partial hydrolysis and cross-linked protein residues were identified by mass spectrom
233 denaturing washes, the resulting covalently linked protein-RNA complexes are purified with oligo(dT)
235 an intra- and intermolecular cysteine cross-linked protein shell called the chlamydial outer membran
237 to the capability to produce multiple cross-linked protein species and polymeric additions to protei
238 re activity in a ligand-dependent manner, we linked protein splicing to cell survival or fluorescence
239 r, we have utilized a genetic selection that links protein stability to antibiotic resistance to isol
240 ndroitin sulfate proteoglycan aggrecan forms link protein-stabilized complexes with hyaluronan (HA),
242 ssumed that a specific ubiquitin ligase (E3) links protein substrates to polyubiquitin chains contain
244 bsence of other glycosylphosphatidylinositol-linked proteins such as urokinase-type plasminogen activ
245 Gs), tenascin-R (TN-R), hyaluronan (HA), and link proteins, such as cartilage link protein 1 (Crtll).
246 duces CaMKIIalpha binding to established ASD-linked proteins, such as Shank3 and subunits of l-type c
247 onan (HA) receptor Lyve-1 is a member of the Link protein superfamily most similar to the leukocyte H
248 results suggest general physical mechanisms linking protein symmetry, the lattice architecture of me
249 propose that specialized machinery exists to link protein synthesis with class I peptide ligand gener
253 accurately estimates functional coupling of linked proteins than use individual data sources alone.
256 y encode glycosyl-phosphatidylinositol (GPI)-linked proteins that are essential for activity of the t
257 ocol for the large-scale purification of Ubl-linked proteins that minimizes sample contamination with
258 (CaMKIIalpha) and a network of functionally linked proteins that regulate neural plasticity and glut
259 10)), encoding plectin, a cytoskeletal cross-linking protein that contributes to integrity of cardiac
260 Filamin A (FlnA) is an important actin cross-linking protein that is required for cellular processes
261 and functions as an actin stress fiber cross-linking protein that promotes the maturation of nascent
264 ave wider implications for other actin cross-linking proteins that share a villin-like headpiece doma
265 ed receptor V1 (adgrv1), another hair bundle link protein, the entry of Cdhr23- and Cdhr15-expressing
266 e 3-deoxythreosone, which modified and cross-linked proteins through the formation of an arginine add
267 anslational modification of the ECM by cross-linking proteins, thus making these proteins resistant t
268 expression of the glycophosphatidylinositol-linked protein Thy-1 affects proliferation and myofibrob
269 nriched for the glycosylphosphatidylinositol-linked protein Thy-1, the ganglioside GM1, palmitoylated
272 omeostasis, or proteostasis, enables disease-linked proteins to adopt aberrant tertiary structures, a
273 to pairs of non-homologous but functionally linked proteins to find specific regions of the protein
278 how they facilitate expanded functions that link protein translation to other cellular pathways.
282 clonal antibody AGG-C1/anti-NITEGE(373)) and link proteins (using monoclonal antibody 8-A-4), as well
284 ytosis of glycosylphosphatidylinositol (GPI)-linked proteins via a specific pathway into GPI-enriched
285 between Capsicum-eIF4E and the viral genome-linked protein (VPg) is required for the viral infection
289 proteolysis assays on this semisynthetic ATP-linked protein, we have obtained unique evidence for an
290 n levels for aggrecan, type II collagen, and link protein were up-regulated approximately 2-3-fold du
291 air or with exogenous oxidant, and the cross-linked proteins were reconstituted to assess their funct
293 ce HA synthetic enzymes (HASs), thus HA, and link proteins, which are scaffolding molecules for an or
294 outer membrane containing a network of cross-linked proteins, which together confer cell envelope sta
295 re also developed in our laboratory by cross-linking proteins while preserving their native structure
296 se of alpha-synuclein, a Parkinson's disease-linked protein whose monomer exhibits significant disord
297 opropyl)carbodiimide (EDC) was used to cross-link proteins with complementary charged groups in close
298 pping uses gene ontology (GO) information to link proteins with similar biological functions from dif
299 e de novo computational design of multicross-linked proteins with predictable and well-defined folds,
300 microtubules are organized by numerous cross-linking proteins yet the mechanical properties of those
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