ライフサイエンスコーパス: lipid droplet

1 l1 is a phospholipase and a component of the lipid droplet.

2 membranes, capsid localizes in nucleoli and lipid droplets.

3 ids that accumulate in its absence reside in lipid droplets.

4 pids in the Tm6sf2(-/-) mice were located in lipid droplets.

5 mic reticulum membrane, and the formation of lipid droplets.

6 ng the activity of lipases on the surface of lipid droplets.

7 phology of AKT-CAT tumors and caused loss of lipid droplets.

8 d in granules including a protein matrix and lipid droplets.

9 in BAT with accumulation of large unilocular lipid droplets.

10 endoplasmic reticulum in a mutant devoid of lipid droplets.

11 associate with HCV core protein residing on lipid droplets.

12 the lipid and pigment compositions of these lipid droplets.

13 d to triglycerides, and stored as unilocular lipid droplets.

14 rentially modulating the number and sizes of lipid droplets.

15 Atg2 expression, permitting deregulation of lipid droplets.

16 in degradation and the dynamic regulation of lipid droplets.

17 ed with a decreased accumulation of TAGs and lipid droplets.

18 istic insights into these novel functions of lipid droplets.

19 Cos7 cells, brown adipocytes, and artificial lipid droplets.

20 ipophagy, a selective autophagy that targets lipid droplets.

21 myofibroblasts through the quantification of lipid droplets.

22 receptor transcriptional activities but more lipid droplets.

23 iculum, where it is esterified and stored in lipid droplets.

24 n, decreased ATP production, and accumulated lipid droplets.

25 iosynthesis and the formation of cytoplasmic lipid droplets.

26 were able to harvest lipids from macrophage lipid droplets.

27 and neurons in the cerebral cortex both show lipid droplet abnormalities.

28 nents, causes protein hypoglycosylation, and lipid droplets accumulate in fibroblasts from patients w

29 ncluding BRD4, reduced Adipoq expression and lipid droplet accumulation in 3T3-L1 adipocytes.

30 ty-related genes, including genes related to lipid droplet accumulation in adipocytes.

31 cific class of effectors is unable to induce lipid droplet accumulation, we demonstrate that the para

32 or-activated receptor gamma (PPARgamma)) and lipid droplet accumulation, whereas adenovirus-mediated

33 pogenesis, as inhibition of miR-33b enhanced lipid droplet accumulation.

34 lin action, increased glucose production and lipid droplet accumulation.

35 pathways that modulate the parasite-induced lipid droplet accumulation.

36 tion of cholesterol, and shows relocation to lipid droplets after HPbetaCD treatment.

37 fferentiation, such as a large number of big lipid droplets, an increase of finger-like protrusions,

38 ted activity of FOXO1&HNF4alpha on CPT2, the lipid droplet and ER-lipid-raft associated PLIN3 and Erl

39 se results provide a direct link between the lipid droplet and proteasomal protein degradation and su

40 are components of the proteinaceous coat of lipid droplets and a single B. bassiana caleosin homolog

41 evealed an association of nsP3 with cellular lipid droplets and examined the spatial relationships be

42 D electron microscopy revealed intracellular lipid droplets and extracellular lipoprotein particles.

43 mechanisms by which autophagosomes recognize lipid droplets and how ATG proteins regulate membrane cu

44 revealed an intriguing relationship between lipid droplets and innate immunity that may represent a

45 SDP1 increased TAG accumulation in cytosolic lipid droplets and markedly enhanced plant tolerance to

46 ne subdomain that is in contact with growing lipid droplets and mediates TAG synthesis.

47 al, but now there are multiple links between lipid droplets and neurodegeneration: many candidate gen

48 ting lipid catabolism to control the size of lipid droplets and prevent the development of obesity an

49 tion, thereby leading to the accumulation of lipid droplets and promoting tumor-associated macrophage

50 cale proteomics analysis of both cytoplasmic lipid droplets and secreted milk fat globule membranes w

51 alpha, Fsp27beta localized on the surface of lipid droplets and suppressed lipolysis.

52 re a link between the storage of histones in lipid droplets and the aberrantly structured chromosomes

53 timulus increase autophagic sequestration of lipid droplets and their degradation in lysosomes.

54 massively accumulated cholesterol ester-rich lipid-droplets and surfactant had an increased proportio

55 olgi, lysosome, peroxisome, mitochondria and lipid droplet) and show how these relationships change o

56 of mitochondria, formation and expansion of lipid droplets, and the rapid and transient ruffling of

57 ifferences in the release of bioactives from lipid droplets, and their solubilization in mixed micell

58 Although lipid droplets are attracting renewed interest from the

59 nd enteroendocrine cells, and viroplasms and lipid droplets are induced.

60 1, these cells continue to cycle and utilize lipid droplets as a source of lipids.

61 on of neutral lipid storage within adipocyte lipid droplets, as well as the possible metabolic benefi

62 inducible protein 2 (HIG2)/hypoxia-inducible lipid droplet-associated (HILPDA) as lipid droplet (LD)

63 Fsp27 is a lipid droplet-associated protein almost exclusively expr

64 Chlamydomonas reinhardtii and contain major lipid droplet-associated protein and enzymes involved in

65 ts as FSP27 or fat-specific protein 27) is a lipid droplet-associated protein that promotes intracell

66 Fat-specific protein 27 (Fsp27) is a lipid droplet-associated protein that promotes lipid dro

67 olysosome formation, and perilipin (PLIN), a lipid droplet-associated protein, suggesting lipophagic

68 ly, we identified a class of plant-specific, lipid droplet-associated proteins (LDAPs) that are abund

69 Unlike all other lipid droplet-associated proteins, PLINs localize almost

70 urring, cholesterol-containing extracellular lipid droplets at the RPE/choroid interface; proteins an

71 Consequently, the lipid droplet became recognized as a unique, metabolical

72 As the cell biology and biochemistry of lipid droplets become increasingly well understood, the

73 cascade of lipogenic signaling to facilitate lipid droplet biogenesis and viral assembly.

74 iation of the CPT1C mutation with changes in lipid droplet biogenesis supports a role for altered lip

75 and proteins involved in membrane remodeling/lipid droplet biogenesis: VESICLE-INDUCING PLASTID PROTE

76 w area of investigation emerged, centered on lipid droplets' biology and their role in energy homeost

77 lipase (HSL) and perilipin 1 (Plin1) in the lipid droplet by protein kinase A (PKA).

78 served 11-mer repeat regions of PLINs target lipid droplets by folding into AHs on the droplet surfac

79 from intracellular metabolic co-factors and lipid droplets can distinguish the functional states of

80 s two types of lipid droplets: cytoplasmatic lipid droplets (CLD) and beta-carotene-rich (betaC) plas

81 e tissue since fasting and refeeding-induced lipid droplet clearance is also attenuated by Bif-1 loss

82 ) is a constitutively associated cytoplasmic lipid droplet coat protein that has been implicated in f

83 Lipid droplets coated by a double-layer of biopolymers (

84 Lipid droplets coated by a single-layer of biopolymers (

85 radiolabeled oleic acid into TAG, accumulate lipid droplets containing TAG and develop phenotypic tol

86 ease in the biosynthesis and accumulation of lipid droplets containing TAG and in its tolerance of ri

87 The dormant pathogen accumulates lipid droplets containing triacylglycerol (TAG).

88 Here, we show that a population of lipid-droplet-containing stromal cells emerges in the de

89 howed reduced retinol (P < 0.001) but higher lipid droplet content (P < 0.001).

90 standing how lipophagy clears hepatocellular lipid droplets could provide new ways to prevent fatty l

91 A new paper by Bailey et al. reveals that lipid droplets, crucial organelles for energy storage, c

92 hat it accumulates under stress two types of lipid droplets: cytoplasmatic lipid droplets (CLD) and b

93 , inhibition of PLA2 significantly decreased lipid droplets, decreased oxidative phosphorylation, and

94 lating testosterone levels despite extensive lipid droplet depletion.

95 , mitochondria, and lipid droplets; however, lipid droplets display weaker mutual activation between

96 edirected to triacylglycerol (TAG) stored in lipid droplets during starvation.

97 Many microbes exploit host cellular lipid droplets during the host-microbe interaction, but

98 In this study, we analyzed the role of lipid droplets during the interaction of Cryptococcus ne

99 H-Fsp27beta axis is important for regulating lipid droplet dynamics and TG storage in the liver.

100 description, we computed the morphology of a lipid droplet embedded in between two identical monolaye

101 ogy of the knockout glands showed very large lipid droplets enclosed in the mammary alveolar cells, b

102 ed expression of Fsp27beta or CREBH promoted lipid droplet enlargement and TG accumulation in the liv

103 trophic adipocytes with large and unilocular lipid droplets exhibited impaired insulin-dependent gluc

104 promoted an increase in the size of cellular lipid droplets following transfection of viral RNA.

105 itis C virus (HCV) relies on host lipids and lipid droplets for replication and morphogenesis.

106 e endoplasmic reticulum for lipid synthesis, lipid droplets for storage and transport, mitochondria a

107 the mitochondria, and forcing fatty acids to lipid droplets for storage.

108 cohort of up-regulated genes associated with lipid droplet formation and lipid transport via lipoprot

109 It is required for unilocular lipid droplet formation and optimal energy storage.

110 tophagy are essential for starvation-induced lipid droplet formation and subsequent ketogenesis and,

111 aired preadipocyte proliferation and reduced lipid droplet formation and the induction of peroxisome

112 only enhances adipocyte differentiation and lipid droplet formation but also results in dysfunctiona

113 Starvation induced massive lipid droplet formation in extra-adipose tissues includi

114 c pool of phosphatidic acid, associated with lipid droplet formation in the perinuclear ER, is respon

115 In contrast, palmitate-induced lipid droplet formation is significantly reduced in HepG

116 lear/endoplasmic reticulum membrane, reduced lipid droplet formation, and temperature sensitivity.

117 pression of adipophilin (PLIN2), a marker of lipid droplet formation, associated with favorable progn

118 doplasmic reticulum membrane morphology, and lipid droplet formation, but not on growth at elevated t

119 esulted in Opi1p being localized to sites of lipid droplet formation, coincident with increased synth

120 They also are involved in lipid droplet formation, enlargement, or both in cells,

121 enzymatic activity, subsequently increasing lipid droplet formation, thereby providing cells with es

122 NLRP3 inflammasome plays a critical role in lipid droplet formation.

123 impaired bacterial restriction, and altered lipid droplet formation.

124 n adipocytes where it facilitates unilocular lipid droplet formation.

125 te adipocytes that contributes to unilocular lipid droplet formation.

126 ads to changes in genes leading to increased lipid droplets formation in hepatocytes resulting in a d

127 pastic paraplegia also have central roles in lipid-droplet formation and maintenance, and mitochondri

128 alization of a three-dimensional assembly of lipid droplets, functionalized with extracellular E-cadh

129 C, also known as FSP27) critically regulated lipid droplet fusion and lipid storage.

130 IDEC, leading to destabilization and reduced lipid droplet fusion.

131 uring Toxoplasma infection, the induction of lipid droplet generation is conserved not only during in

132 umulation of neutral lipids in intracellular lipid droplets has been associated with the formation an

133 Lipid droplets have also emerged as important nodes for

134 Lipid droplets have been known to maintain endoplasmic r

135 s a mechanism by which cytokines can control lipid droplet homeostasis and consequently resistance to

136 In mammals, perilipin regulates lipid droplet homeostasis but no such protein has been i

137 ions including microsomes, mitochondria, and lipid droplets; however, lipid droplets display weaker m

138 scaffold protein at the surface of cytosolic lipid droplets in adipocytes, marked a fundamental conce

139 mapping polymer particles in 3D volumes and lipid droplets in adipose cells.

140 However, it also reduced lipid droplets in AKT-NRAS(G12V) tumors.

141 ion of oleic acid increased the frequency of lipid droplets in both C. neoformans and macrophages.

142 de receptors [(Fprs) 1, 2, and 3], a loss of lipid droplets in cortical cells (index of availability

143 In Drosophila larvae, lipid droplets in glia allow neuronal stem cells to keep

144 hese actions resulted in the accumulation of lipid droplets in hepatocytes and systemic hyperlipidemi

145 The accumulation of lipid droplets in infected hepatocytes manifests as hepa

146 way of studying and understanding cytosolic lipid droplets in living cells.

147 in vol/vol concentration units of individual lipid droplets in living human adipose-derived stem cell

148 the size, number and spatial distribution of lipid droplets in living mouse oocytes and embryos up to

149 t differences in the chemical composition of lipid droplets in living oocytes matured in media supple

150 t staining has previously been used to image lipid droplets in mammalian oocytes and embryos, but thi

151 l role in the homeostasis of TAG -containing lipid droplets in Mtb and influences the entry of the pa

152 eurons can lead to transient accumulation of lipid droplets in neighboring glial cells, an event that

153 We also observed a reduction of mean (SD) lipid droplets in primary cortical neurons isolated from

154 hed by the accumulation of large cytoplasmic lipid droplets in the alveolar epithelial cells.

155 by the accumulation of triglycerides (TG) as lipid droplets in the liver.

156 nocyte proliferation, and an accumulation of lipid droplets in the stratum corneum.

157 This TAG accumulated in lipid droplets in the tgd2 mutant under normal growth co

158 creased adiposity, and steatosis, with large lipid droplets in their hepatocytes.

159 tic LPL deletion reduced the accumulation of lipid droplets in those glial cells.

160 that Tgl4p and Tgl5p, which are localized to lipid droplets in wild type, are partially retained in t

161 fic structures, namely fluorescently labeled lipid droplets, in lamellas that are 300 nm thick.

162 ation and suggest that dynamic regulation of lipid droplets is a key aspect of some proteotoxic stres

163 Lipid droplet (LD) accumulation is a hallmark of hypoxic

164 Lipid droplet (LD) biogenesis and conversion of phosphol

165 h triacsin C, a fatty acid analogue, impairs lipid droplet (LD) biogenesis and ERAD, suggesting a rol

166 ipodystrophy protein SEIPIN is important for lipid droplet (LD) biogenesis in human and yeast cells.

167 sess higher levels of perilipin 5 (PLIN5), a lipid droplet (LD) coating protein.

168 ns constitute an ancient family important in lipid droplet (LD) formation and triglyceride metabolism

169 This study was designed to characterize lipid droplet (LD) formation in EC by manipulating pathw

170 The lipid droplet (LD) fraction of milk has attracted specia

171 Lipid droplet (LD) functions are regulated by a compleme

172 pid droplet-associated protein that promotes lipid droplet (LD) growth and triglyceride (TG) storage

173 ) are stored in the membrane-bound organelle lipid droplet (LD) in essentially all eukaryotic cells.

174 eipin is necessary for both adipogenesis and lipid droplet (LD) organization in nonadipose tissues; h

175 Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been observ

176 We tested our hypothesis that lipid droplet (LD) protein perilipin 5 (PLIN5) in beta-c

177 ducible lipid droplet-associated (HILPDA) as lipid droplet (LD) protein.

178 s from Lxralphabeta(-/-) mice have increased lipid droplet (LD) size, but the functional consequences

179 very-low-density lipoproteins, and increased lipid droplet (LD) stability.

180 Lipid droplet (LD), a multi-functional organelle, is oft

181 Lipid droplet (LD), a ubiquitous organelle in mammalian

182 Lipid droplet (LD)-associated hydrolase (LDAH) is a newl

183 ABSTRACT: Because the lipid droplet (LD)-associated perilipin (PLIN) proteins

184 KEY POINTS: The lipid droplet (LD)-associated perilipin (PLIN) proteins

185 s under hypoxic and acidic stress acquired a lipid droplet (LD)-loaded phenotype, and showed an incre

186 Lipid droplets (LD) are dynamic organelles involved in i

187 chondrial dysfunction is the accumulation of lipid droplets (LD) in glia.

188 aracterized by neutral lipid accumulation in lipid droplets (LD) of hepatocytes.

189 Because the ACSL inhibitors can deplete lipid droplets (LD), we used a cell line where LD synthe

190 zation to putative virus assembly sites near lipid droplets (LD).

191 ive triglyceride accumulation in the form of lipid droplets (LD); however, mechanisms differ in drug

192 dden glucose depletion, yeast cells activate lipid-droplet (LD) consumption through micro-lipophagy (

193 FAEEs were transiently incorporated into lipid droplets (LDs) and both Yju3p and MGL co-localized

194 Lipid droplets (LDs) are conserved organelles for intrac

195 Plant cytosolic lipid droplets (LDs) are covered with a layer of phospho

196 Lipid droplets (LDs) are cytosolic organelles that protr

197 Storage and consumption of neutral lipids in lipid droplets (LDs) are essential for energy homeostasi

198 Lipid droplets (LDs) are found in all cells and play cri

199 Cytoplasmic lipid droplets (LDs) are found in all types of plant cel

200 Triacylglycerols (TGs) stored in lipid droplets (LDs) are hydrolyzed in a highly regulate

201 Lipid droplets (LDs) are intracellular organelles that p

202 Lipid droplets (LDs) are lipid storage organelles that g

203 Lipid droplets (LDs) are phylogenetically conserved cyto

204 Lipid droplets (LDs) are sometimes found in the nucleus

205 Lipid droplets (LDs) are storage organelles consisting o

206 Intracellular lipid droplets (LDs) are the main cellular site of metab

207 Lipid droplets (LDs) are ubiquitous organelles in plant

208 In mammals, lipid droplets (LDs) are ubiquitous organelles that modu

209 tored in seed tissues, where the assembly of lipid droplets (LDs) coincides with the accumulation of

210 During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerols (TAGs),

211 at both LC3 and SQSTM1 could colocalize with lipid droplets (LDs) following ethanol treatment.

212 Lipid droplets (LDs) hypertrophy in adipocytes is the ma

213 Here we discover that microtubule-associated lipid droplets (LDs) in COS1 cells respond to an optical

214 donor mitochondria; however, the fraction of lipid droplets (LDs) in direct contact with a mitochondr

215 Subcellular lipid droplets (LDs) in diverse plant cells and species

216 in motors are recruited to triglyceride-rich lipid droplets (LDs) in the liver by the GTPase ARF1, wh

217 The labeled FA accumulated in lipid droplets (LDs) in well-fed cells but moved from LD

218 tested whether the fraction of PLIN5-coated lipid droplets (LDs) is a determinant of skeletal muscle

219 Even distribution of peroxisomes (POs) and lipid droplets (LDs) is critical to their role in lipid

220 proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood.

221 ocation of nuclear CCTalpha onto cytoplasmic lipid droplets (LDs) is proposed to stimulate the synthe

222 KA in the regulation of TG mobilization from lipid droplets (LDs) is unknown.

223 Cytoplasmic lipid droplets (LDs) of neutral lipids (triacylglycerols

224 Lipid droplets (LDs) provide an "on-demand" source of fa

225 that CDCP1 depletes lipids from cytoplasmic lipid droplets (LDs) through reduced acyl-CoA production

226 reactors induces a sustained accumulation of lipid droplets (LDs) without compromising growth, which

227 type: polystyrene nanosphere size standards, lipid droplets (LDs), and large unilamellar vesicles (LU

228 for the first time, that peroxisomes (POs), lipid droplets (LDs), and the endoplasmic reticulum (ER)

229 talize neutral lipids into organelles called lipid droplets (LDs), and while much is known about the

230 TAGs), present in Arabidopsis guard cells as lipid droplets (LDs), are involved in light-induced stom

231 ian cancer cell lines) resulted in increased lipid droplets (LDs), reduced autophagic vacuoles (AVs)

232 ers in close proximity to the apical side of lipid droplets (LDs).

233 steatosis is defined by the accumulation of lipid droplets (LDs).

234 ge neutral lipid storage organelles known as lipid droplets (LDs).

235 and colocalize with HCV core protein around lipid droplets (LDs).

236 stored within the cellular organelles termed lipid droplets (LDs).

237 n of triglyceride (TG) and PNPLA3 in hepatic lipid droplets (LDs).

238 olamine activation of the PKA pathway and of lipid droplet lipolysis with transcriptional regulation

239 eletion of AnxA1 or Fpr2/3 in mice prevented lipid droplet loss, but not leukocyte infiltration.

240 1, Fpr1, and Fpr3 mRNAs but had no impact on lipid droplet loss.

241 ve effect on triglycerides mobilization from lipid droplets, mediated by inhibition of other lipases.

242 physicochemical environment has on both the lipid droplet microstructure and the lipid release patte

243 indices of generalized adipogenesis, such as lipid droplet morphology and fatty acid binding protein

244 d an increase in triacylglycerol content and lipid droplet number in cells expressing the Nem1-Spo7 p

245 ize (0.29 [0.01] vs 0.26 [0.01]; P < .05) of lipid droplets on overexpression in cells.

246 , invadolysin is localized on the surface of lipid droplets, organelles that store not only triglycer

247 inhibitors, suggesting that the turnover of lipid droplets overcomes the autophagic clearance.

248 t these host organelles, which suggests that lipid droplets play a critical role at the coccidian hos

249 ccumulating evidence suggests that the roles lipid droplets play in biology are significantly broader

250 s increasing evidence showing that cytosolic lipid droplets, present in all eukaryotic cells, play a

251 The major lipid droplet protein (MLDP) forms a proteinaceous coat

252 Perilipin 5 (PLIN5) is a lipid droplet protein and is highly expressed in oxidati

253 Pet10p is a yeast lipid droplet protein of unknown function.

254 We previously reported that the lipid droplet protein perilipin 2 (PLIN2) modulates lipi

255 Here we identify the lipid droplet protein Perilipin 5 as a catecholamine-tri

256 proliferator-activated receptor gamma 2 and lipid-droplet protein fat-specific protein 27 beta.

257 Perilipin 2 (PLIN2) is a lipid-droplet protein that is up-regulated in alcoholic

258 of ATGL, and negatively with mRNA levels of lipid droplet proteins, perilipin, and TIP47 in human su

259 was constructed to aid the identification of lipid droplet proteins.

260 pted in genes encoding proteins of the algal lipid droplet proteome.

261 Our results show that detection of lipid droplets provides a robust readout to screen for r

262 otypes are ameliorated by a reduction of the lipid-droplet-resident protein PLIN2.

263 Association of XOR with the lipid droplet results in membrane docking and more effic

264 ATG proteins regulate membrane curvature for lipid droplet sequestration, and comment on the possibil

265 HCV infection, YTHDF proteins relocalize to lipid droplets, sites of viral assembly, and their deple

266 rovilli and enterocyte lengths and decreased lipid droplet size in the intestinal epithelium.

267 pression in 3T3-L1 adipocytes did not affect lipid droplet size or cell viability but did increase au

268 deficiency reduces TG storage and diminishes lipid droplet size through inhibition of Ppargamma expre

269 ipocytes to blue light resulted in decreased lipid droplet size, increased basal lipolytic rate and a

270 Intracellular lipid droplet synthesis was followed in Phaeodactylum tr

271 pathic helices (AHs) significantly decreased lipid droplet targetingin vivoandin vitro Finally, we de

272 uction of a selective autophagy that targets lipid droplets, termed lipophagy.

273 as evaluated by microscopy, revealing larger lipid droplets than the wild type.

274 Mammalian oocytes contain lipid droplets that are a store of fatty acids, whose me

275 simultaneously help with the accumulation of lipid droplets that are not cleared effectively by autop

276 This study reveals an antioxidant role for lipid droplets that could be relevant in many different

277 Lipid droplets that form in niche glia during oxidative

278 otein and the nucleoporin Nup98 at cytosolic lipid droplets that is important for HCV propagation.

279 Furthermore, in lipid droplets, the phosphorylation of HSL and Plin1 and

280 Autophagy degrades lipid droplets through a process termed lipophagy.

281 tion results in increased biogenesis of host lipid droplets through rewiring of multiple components o

282 ophagy delivers cellular products, including lipid droplets, to lysosomes.

283 including components of glucose metabolism, lipid droplet trafficking, and cytoskeletal organization

284 y disrupted lipolysis without affecting ATGL lipid droplet translocation or ABHD5 interactions with p

285 survival within macrophages by deregulating lipid droplets via ATG2 repression.

286 ations of small (d=44nm) and large (d=216nm) lipid droplets was examined.

287 b1 levels were increased and accumulation of lipid droplets was observed, indicative of a blockade of

288 ce, small adipocytes containing multilocular lipid droplets were dispersed.

289 In Ctrl and LL cells, micron-sized lipid droplets were found to increase in number througho

290 LLC presenting small lipid droplets were visualized adjacent to blood vessels

291 as converted to cholesteryl esters stored in lipid droplets when ORP1L was bound to RIDalpha.

292 eic acid, away from membranes to the core of lipid droplets, where they are less vulnerable to peroxi

293 We also detected lipid droplets, which became larger and more numerous as

294 ted checkpoint forces these cells to utilize lipid droplets, which could potentially lead to therapeu

295 icles containing granules, mitochondria, and lipid droplets, which we designated as granule-containin

296 SEIPIN1 promoted accumulation of large-sized lipid droplets, while expression of SEIPIN2 and especial

297 d at the point of contact of the cytoplasmic lipid droplet with the apical plasma membrane, in the wi

298 Plant cells contain subcellular lipid droplets with a triacylglycerol matrix enclosed by

299 d by a 40-fold increase in PNPLA3 on hepatic lipid droplets, with no increase in hepatic PNPLA3 messe

300 th this, we observed significantly increased lipid droplets, with subsequent mobilization to mitochon

301 by conventional methods, including extensive lipid droplets within glioma cells, collagen deposition