ライフサイエンスコーパス: lipid metabolism

1 use models (such as pathways associated with lipid metabolism).

2 ia (mitochondrial dysfunction and defects in lipid metabolism).

3 elated to nucleotide-dependent processes and lipid metabolism.

4 activities ranging from Ca(2+) signaling to lipid metabolism.

5 d UPR signaling effects important changes in lipid metabolism.

6 dulation of the peripheral immune system and lipid metabolism.

7 ays an important role in regulating mosquito lipid metabolism.

8 iated genes, indicating a role of SLC7A11 in lipid metabolism.

9 JAK2 signals to regulate insulin/glucose and lipid metabolism.

10 xpression, particularly of genes involved in lipid metabolism.

11 ns involved in epidermal differentiation and lipid metabolism.

12 ription factor that has an important role in lipid metabolism.

13 ays used by fructose and glucose to regulate lipid metabolism.

14 behavior of functional ER in the context of lipid metabolism.

15 ls and DNA damage, linking these features to lipid metabolism.

16 a potential link between visual displays and lipid metabolism.

17 he regulation of INO1 expression and overall lipid metabolism.

18 porter involved in nutrient flux and hepatic lipid metabolism.

19 d to cell signalling, the immune system, and lipid metabolism.

20 ting a widespread circadian impact on muscle lipid metabolism.

21 cating that GIP also plays a crucial role in lipid metabolism.

22 ns as a hormone to regulate carbohydrate and lipid metabolism.

23 RNA pairs and their regulatory roles in duck lipid metabolism.

24 AT3 as a novel enzyme involved in intestinal lipid metabolism.

25 ng, leading to altered insulin, glucose, and lipid metabolism.

26 induced by insulin and is a key regulator of lipid metabolism.

27 thesis of plasma proteins and integration of lipid metabolism.

28 unctions as a circadian regulator of hepatic lipid metabolism.

29 sm by which Lcn2 regulates thermogenesis and lipid metabolism.

30 icosanoid pathway, which are associated with lipid metabolism.

31 a-aminoisobutyric acid (BAIB)-a modulator of lipid metabolism.

32 ressed only in the liver, where it regulates lipid metabolism.

33 ified compensatory changes in amino acid and lipid metabolism.

34 s in insect immune responses associated with lipid metabolism.

35 exhibits dual functions in the regulation of lipid metabolism.

36 health and may affect insulin resistance and lipid metabolism.

37 uture research on regulation network in duck lipid metabolism.

38 protein catabolism, ureagenesis, and hepatic lipid metabolism.

39 -2 (SREBP2) that regulates genes involved in lipid metabolism.

40 ral nuclear receptors that regulate drug and lipid metabolism.

41 role of the Hedgehog pathway in adult liver lipid metabolism.

42 that MeCP2 plays a direct role in regulating lipid metabolism.

43 fficking, but not in tissues associated with lipid metabolism.

44 induction of LXR-regulated genes and altered lipid metabolism.

45 rcadian clock synchronization of glucose and lipid metabolism.

46 (PPARdelta) regulates many genes involved in lipid metabolism.

47 lso demonstrated propensity to modulate host lipid metabolism.

48 13-HODE also perturbed proteins related to lipid metabolism.

49 -1 and lxralpha, major regulators of hepatic lipid metabolism.

50 elle in mammalian cells, serves as a hub for lipid metabolism.

51 in transducing nutritional state to regulate lipid metabolism.

52 ess, impaired autophagy, and deregulation of lipid metabolism.

53 were more typical on proteins involved with lipid metabolism.

54 t, bioelectric signaling, and amino acid and lipid metabolism.

55 also in tryptophan/serotonin, bile acid and lipid metabolism.

56 that can modulate Wnt signaling and aberrant lipid metabolism.

57 iring of multiple components of host neutral lipid metabolism.

58 June 2016.Diabetes is a disorder of abnormal lipid metabolism, a notion strongly supported by the wor

59 h insulin resistance and deregulation of the lipid metabolism (accumulation of lipotoxins that promot

60 y delayed, while changes at loci involved in lipid metabolism affect gene expression and the resultin

61 Functional annotations highlight lipid metabolism and a change in the stress response cap

62 Obesity is associated with dysregulated lipid metabolism and adipokine secretion.

63 ne a regulatory role for a non-coding RNA in lipid metabolism and advance our understanding of the me

64 ach phagocyte, including macrophage-specific lipid metabolism and amino acid catabolism, and a dendri

65 Monoglycerides play a central role in lipid metabolism and are important signaling metabolites

66 sex chromosome complement each contribute to lipid metabolism and associated diseases, and the curren

67 le of Panx1 in linking lymphatic function to lipid metabolism and atherosclerotic plaque development.

68 sion of circadian-clock genes to impact host lipid metabolism and body composition.

69 enables sex-specific regulation of muscular lipid metabolism and body weight by repressing estrogen

70 between the well-known effects of alcohol on lipid metabolism and cardiovascular risk, with light alc

71 tic sympathetic nerves increases glucose and lipid metabolism and contributes to the elevated hepatic

72 naling in post-transcriptional regulation of lipid metabolism and demonstrate that SRPK2 is a potenti

73 action involves alteration of mitochondrial lipid metabolism and differentiation of breast cancer ce

74 r, imparting sex differences in hepatic drug/lipid metabolism and disease risk.

75 regulation of genes related to PPAR-mediated lipid metabolism and downregulation of genes in the reti

76 functional characterization revealed altered lipid metabolism and elevated ROS as hallmarks of the ce

77 plasmic reticulum (ER) cooperate in cellular lipid metabolism and form tight structural associations,

78 FAS exposures during pregnancy may influence lipid metabolism and glucose tolerance and thus may impa

79 PAT affected microbial lipid metabolism and host cholesterol biosynthetic gene

80 However, the molecular links between lipid metabolism and IL-1beta production remain obscure.

81 physiological functions such as glucose and lipid metabolism and immune function.

82 allow for a closer look at the interplay of lipid metabolism and immune regulation during host infec

83 associated with pathways involved in hepatic lipid metabolism and immunological processes.

84 Obesity is associated with abnormal lipid metabolism and impaired bone homeostasis.

85 tions are observed in vesicular trafficking, lipid metabolism and in the endoplasmic reticulum that c

86 showed that SGLT2 inhibition modulates renal lipid metabolism and inflammation and prevents the devel

87 ose of adiponectin in regulating glucose and lipid metabolism and insulin sensitivity.

88 r following oral dosing, leading to improved lipid metabolism and insulin sensitization in mice.

89 lism.HDAC3 is a critical mediator of hepatic lipid metabolism and its loss leads to fatty liver.

90 mber and expresses multiple genes related to lipid metabolism and lipid signaling.

91 tion factor EB (TFEB), a master regulator of lipid metabolism and lysosomal biogenesis and function.

92 SKbeta-PPARalpha axis that regulates hepatic lipid metabolism and may provide unique targets for the

93 nables non-invasive investigation of cardiac lipid metabolism and may thus be a useful tool to study

94 Among these, lipid metabolism and mitochondrial dysfunction proteins

95 ted traumas, and two modules associated with lipid metabolism and mitogen-activated protein kinase ac

96 fficking, defense signaling through membrane lipid metabolism and mucilage production.

97 Specifically, metabolites involved in lipid metabolism and oxidative phosphorylation are alter

98 ks at promoter and enhancers of genes in the lipid metabolism and phagocytic pathways.

99 hondria exert critical functions in cellular lipid metabolism and promote the synthesis of major cons

100 nsulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation.

101 s, miR-277 plays a critical role in mosquito lipid metabolism and reproduction by targeting ilp7 and

102 These results highlight the potential of lipid metabolism and ROS as therapeutic targets for redu

103 Hence, thylakoid lipid metabolism and TAG formation increases thermotoler

104 ressed in immature leaves, genes involved in lipid metabolism and tetrapyrrole synthesis were highly

105 xhibit mitochondrial dysfunction and altered lipid metabolism and that carnitine palmitoyltransferase

106 hatatRA regulates mitochondrial function and lipid metabolism and that increasingatRA concentrations

107 de new insights into the complexity of plant lipid metabolism and the challenges associated with pred

108 PPARdelta transcriptionally modulates lipid metabolism and the control of energy homeostasis;

109 monstrate a connection between mitochondrial lipid metabolism and the differentiation program of brea

110 the Ime4 protein provides new insights into lipid metabolism and the pathophysiology of lipid-relate

111 y unidentified link between O-GlcNAcylation, lipid metabolism and the regulation of SREBP-1 in cancer

112 tractin, which are involved in inflammation, lipid metabolism and vascular health.

113 serine or cysteine enzymes involved in M. tb lipid metabolism and/or in cell wall biosynthesis.

114 amics, which showed direct links to cellular lipid metabolisms and can separate LDs involved in diffe

115 y weight and fasting blood glucose, improved lipid metabolism, and also reduced hepatic steatosis in

116 levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with d

117 for genes regulating the cell cycle, glucose/lipid metabolism, and expression of epigenetic modifiers

118 studies that perturbations in endolysosomal, lipid metabolism, and immune response pathways substanti

119 The liver plays a central role in lipid metabolism, and impaired response to fasting and f

120 expression of genes involved in glucose and lipid metabolism, and increases plasma and liver triglyc

121 of the miR-29 family on glucose metabolism, lipid metabolism, and insulin responsiveness in skeletal

122 lase HDAC3 is a critical mediator of hepatic lipid metabolism, and liver-specific deletion of HDAC3 l

123 s key genes required for beta-cell identity, lipid metabolism, and mitochondrial fatty acid and solut

124 al biological processes, such as cell death, lipid metabolism, and molecular transport.

125 teins including those involved in signaling, lipid metabolism, and potassium ion transport.

126 oic acid (ATRA) on body weight and fat mass, lipid metabolism, and retinoic acid signaling pathway ac

127 Outside of its role in lipid metabolism, ANGPTL4 signaling remains poorly under

128 the mechanisms through which oncogenes alter lipid metabolism are poorly understood.

129 Glucose and lipid metabolism are radically altered in hypoxic RPE ce

130 mine biosynthetic pathway, glycosylation and lipid metabolism as crucial for cancer - endothelial cel

131 e Cancer Genome Atlas dataset, we identified lipid metabolism as the metabolic pathway that most sign

132 s exposure induced disturbance of energy and lipid metabolism as well as oxidative stress.

133 an 200 proteins, including known proteins of lipid metabolism, as well as 74 proteins uniquely presen

134 These results suggest that perturbations in lipid metabolism associated with late endosomal/lysosoma

135 es observed imply differential regulation of lipid metabolism between the different tissue types of t

136 cells to various oxygen levels alters their lipid metabolism, but detailed studies examining how hyp

137 mechanism by which ER stress plays a role in lipid metabolism by examining its ability to modulate PC

138 sults demonstrate that CCDC3 modulates liver lipid metabolism by inhibiting liver de novo lipogenesis

139 l membrane proteins that control glucose and lipid metabolism by mediating, at least in part, a cellu

140 at retinol saturase is implicated in hepatic lipid metabolism by regulating the activity of the trans

141 new insights into the regulation of hepatic lipid metabolism by the ubiquitin-proteasome system and

142 include regulation of (a) adipogenesis, (b) lipid metabolism, (c) inflammation, (d) adipocyte apopto

143 ssect the complex roles of phospholipases in lipid metabolism, cellular signaling and immune regulati

144 omplex lipids may be mechanisms underpinning lipid metabolism changes that typify advancing CKD.

145 tes involved in glycolysis, gluconeogenesis, lipid metabolism, citric acid cycle, and neurodevelopmen

146 Dysfunctional cellular lipid metabolism contributes to common chronic human dis

147 This lipid metabolism creates a dependency on pathways conver

148 fatty acids, acylcarnitines, and products of lipid metabolism decreased and triglycerides increased d

149 l mice only transiently affected glucose and lipid metabolism, did not affect muscle wasting, but dra

150 Given the conservation of lipid metabolism, dietary or endogenous MUFAs could exte

151 is because of the marked impacts of elevated lipid metabolism, disruption of iron homeostasis and pos

152 es) was enriched for the glyoxylate pathway, lipid metabolism, diterpenoid biosynthesis and responses

153 Results suggest that rapid plastid lipid metabolism drives TAG accumulation during heat str

154 llular proliferation, circadian rhythms, and lipid metabolism during liver regeneration in mice.

155 Here we report the mechanism of lipid metabolism dysregulation in TNBC through the prome

156 ate potential interactions between RPE65 and lipid metabolism enzymes, HEK293-F cells were transfecte

157 ntified altered expression of genes encoding lipid-metabolism enzymes, skin barrier-associated transc

158 Genes involved in lipid metabolism, especially omega-6 fatty acid metaboli

159 relatively low mTORC1 activity and increased lipid metabolism, expresses increased amounts of anti-ap

160 the brain and within organs specialized for lipid metabolism (fat bodies and oenocytes).

161 In view of the advantages in lipid metabolism features, hamster models are ideally su

162 ed several clinically relevant inhibitors of lipid metabolism for their ability to eliminate primary

163 vely, these results suggest that the altered lipid metabolism found in NF2-mutant cells renders them

164 a2 transcriptional targets were enriched for lipid metabolism genes, and mga2Delta cells showed disru

165 eir enhancers and inhibits the expression of lipid metabolism genes, including PPAR-gamma, by directl

166 es myofibrillar, mitochondrial and oxidative lipid metabolism genes, necessary for muscle adaptation.

167 rsening of IMGU; and decreased expression of lipid metabolism genes.

168 review, we will discuss the role of hepatic lipid metabolism, genetic background, diet, and physical

169 Since the regulation networks in duck lipid metabolism had not been reported very clearly, we

170 addition to favorable effects on glucose and lipid metabolism, has shown nitric oxide (NO)-dependent

171 Deregulated Wnt signaling and altered lipid metabolism have been linked to obesity, diabetes,

172 Mutations in genes involved in lipid metabolism have increasingly been associated with

173 ing in linking mitochondrial homeostasis and lipid metabolism.High-throughput genetic screens in anim

174 zed as an important regulator of glucose and lipid metabolism homeostasis.

175 rther corroborated our findings of increased lipid metabolism in AIS.

176 dynamic organelles involved in intracellular lipid metabolism in almost all eukaryotic cells, and LD-

177 microsporus provide important insights into lipid metabolism in an understudied group of oleaginous

178 croscopy, define a role for BMP signaling in lipid metabolism in C. elegans.

179 ht to determine the role of ACOT1 in hepatic lipid metabolism in C57Bl/6J male mice 1 week after aden

180 Here we show that O-GlcNAcylation modulates lipid metabolism in cancer cells.

181 tailed studies examining how hypoxia affects lipid metabolism in chondrocytes are lacking.

182 e tissue was associated with the collapse of lipid metabolism in favor of antimicrobial responses.

183 e LXR-mediated transcription and to modulate lipid metabolism in hepatocytes.

184 -1 secretion and improve hepatic glucose and lipid metabolism in high-fat diet-induced obese mice.

185 rnandez et al. evaluated hepatic glucose and lipid metabolism in humans and mice following a single o

186 ominal adipose tissue blood flow (ATBF), and lipid metabolism in humans.

187 sensitivity, hepatic glucose metabolism, and lipid metabolism in humans.

188 We investigated lipid metabolism in inducible intestine-specific and liv

189 al chemical imaging of DNA, RNA, protein and lipid metabolism in live rat brain hippocampal tissues b

190 ing of compounds or interventions that alter lipid metabolism in liver cell cultures.

191 This method opens a way to quantify lipid metabolism in living cells during cellular develop

192 ssion of structural proteins, fatty acid and lipid metabolism in LS180 cells.

193 le in the maintenance of gluconeogenesis and lipid metabolism in males.

194 significance of ERAD-mediated regulation of lipid metabolism in mammalian cells.

195 els and human samples, that dysregulation of lipid metabolism in NAFLD causes a selective loss of int

196 t evidence suggests that altered myocellular lipid metabolism in obesity may lead to increased insuli

197 erged as important regulators of glucose and lipid metabolism in several tissues; however, their role

198 ytes suggesting that CGI-58 is essential for lipid metabolism in suprabasal epidermal layers.

199 tailed analysis of gallbladder bile acid and lipid metabolism in Tgr5(-/-) mice in both free-fed and

200 al protein regulating TNFalpha signaling and lipid metabolism in the adipose tissue through modulatio

201 onounced inflammatory responses and abnormal lipid metabolism in the liver.

202 ) is a hepatokine that regulates glucose and lipid metabolism in the liver.

203 n-3 supplementation during pregnancy affects lipid metabolism in the placentas of overweight and obes

204 ere we investigate the mechanisms of neutral lipid metabolism in the preexisting LD pool.

205 des and free fatty acids, suggesting altered lipid metabolism in these Panx1-deficient mice.

206 rogress in basic research on plant and algal lipid metabolism, in combination with advances in synthe

207 show delayed larval development and altered lipid metabolism, in particular induced lipolysis upon s

208 an skeletal muscle oscillators in regulating lipid metabolism independent of external synchronizers,

209 nscript and metabolite subnetworks linked to lipid metabolism, inflammation and glycerophospholipid m

210 Lipid metabolism is a highly treatable target; therefore

211 Neutral lipid metabolism is a key aspect of intracellular homeos

212 Plant seed lipid metabolism is an area of intensive research, inclu

213 Dysregulation of lipid metabolism is associated with many diseases includ

214 Dysregulation of lipid metabolism is common in breast cancer.

215 disease mechanism and the finding that glial lipid metabolism is critical for axon function, independ

216 Optimal control of hepatic lipid metabolism is critical for organismal metabolic fi

217 ongoing discussion that the manipulation of lipid metabolism is crucial for DENV replication and inf

218 For example, lipid metabolism is distributed between the endoplasmic

219 Lipid metabolism is increasingly being appreciated to af

220 The recognition of perturbed lipid metabolism is only recently becoming evident in HD

221 , a computational model of liver glucose and lipid metabolism is presented which treats the sinusoid

222 s for detecting membrane composition and how lipid metabolism is regulated in response to membrane st

223 ledge about the function of 14-3-3s in plant lipid metabolism is sparse.

224 The enzyme playing a major role in lipid metabolism is subject to phosphorylation (e.g. by

225 Liver lipid metabolism is under intricate temporal control by

226 with pleiotropic effects on carbohydrate and lipid metabolism, is considered a target for the treatme

227 Genes involved in lipid metabolism, known to be involved in cold acclimati

228 is (G26R, W50R, F71Y, and L170P) or aberrant lipid metabolism (L159R).

229 ing brain functions and circuitry, including lipid metabolism, leukocyte migration and olfaction.

230 e multifunctional lipid derivatives to study lipid metabolism, lipid-protein interactions, and intrac

231 nity and further suggest that alterations in lipid metabolism may affect iNKT cell homeostasis throug

232 nes involved in motility, energy metabolism, lipid metabolism, metal transport, and antioxidant enzym

233 ify apo(a) as an additional component of the lipid metabolism modulating HCV infection.

234 and GLP-1 secretion and improved glucose and lipid metabolism more than did the FXR-selective obetich

235 reased Ppargamma2, Fabp4, and Plin1; several lipid metabolism mRNAs; coincident hypermethylation of t

236 method for in vivo investigation of cardiac lipid metabolism: namely, IVS-McPRESS.

237 ays in blood vessel morphogenesis as well as lipid metabolism, nitric oxide signaling and inflammatio

238 nesfatin-1 modulates the differentiation and lipid metabolism of brown adipocytes remains unknown.

239 Changes in the lipid metabolism of cancerous cells can provide importan

240 We investigated if and how MFSD2A regulates lipid metabolism of gut endothelial cells to promote res

241 lecule by LC-MS suggests that 2AI alters the lipid metabolism of RPE cells, enhancing the intracellul

242 the ability of citrus flavonoids to modulate lipid metabolism, other metabolic parameters related to

243 A underlined the effects of PFOS exposure on lipid metabolism, oxidative stress and cell junction sig

244 observed marked upregulation of protein and lipid metabolism particularly in the hilus region of the

245 n and its functional implications in hepatic lipid metabolism, particularly in the context of fatty l

246 ween LMW-E isoforms of cyclin E and aberrant lipid metabolism pathways in breast cancer tumorigenesis

247 es indicate that Notch activation suppresses lipid metabolism pathways that supply ligands to Ppargam

248 in atherosclerosis-related inflammatory and lipid metabolism pathways, and inhibited cell migration

249 urrent changes in the expression of genes in lipid metabolism pathways.

250 number of physiological processes, including lipid metabolism, phospholipid exchange, metabolite tran

251 as potential diagnostic biomarkers and that lipid metabolism plays a role in the pathogenesis of AIS

252 reprogramming, suggesting increased hepatic lipid metabolism prior to overt tumor development.

253 oneogenesis, TCA cycle, starch biosynthesis, lipid metabolism, protein biosynthesis and processing.

254 ched in a few functional categories, such as lipid metabolism, protein metabolism, and gene expressio

255 toplasmic, cytoskeletal, Golgi apparatus and lipid metabolism proteins associated with the secreted m

256 nitrogen-deprived E. oleoabundans, including lipid metabolism, provides insights into the basic biolo

257 onsumption, and smoking were associated with lipid metabolism (reduced lyso- and acyl-alkyl-phosphati

258 r data candidate PCSK9 as a gene involved in lipid metabolism regulated by proinflammatory cytokine T

259 of axon-glia interactions, with Schwann cell lipid metabolism regulating the anchorage of juxtaparano

260 a new function for EGFR kinase activity as a lipid metabolism regulator in regenerating hepatocytes.

261 netic experiments found additional VLCFA and lipid metabolism-related mutants with increased Pro accu

262 iated gene, Fos-related antigen2 (Fosl2) and lipid-metabolism-related gene, Fatty acid elongase 4 (El

263 ct hormone biosynthesis pathway and also 747 lipids metabolism-related unigenes that may be insightfu

264 Conventional assays on the measurement of lipid metabolism rely on the quantification of the lipid

265 sue and differential expression of genes for lipid metabolism, signaling, stress, transport, cell cyc

266 l functions, it is evident that dysregulated lipid metabolism signifies a key element in many patholo

267 ling intervention in conditions of perturbed lipid metabolism such as obesity and type 2 diabetes but

268 nts are generally aimed at altering systemic lipid metabolism such that atherogenesis, the formation

269 nes that may be insightful to understand the lipid metabolism system in pangolins.

270 f SLC16A11 induces changes in fatty acid and lipid metabolism that are associated with increased T2D

271 ed mice revealed novel regulators of hepatic lipid metabolism that are responsive to miR-122 inhibiti

272 of potential evolutionary adaptations within lipid metabolism that probably enhance HFA production an

273 ffraction limit to detect small variation in lipid metabolism that was conventionally undetectable.

274 y used as a model vertebrate system to study lipid metabolism, the roles of lipids in diseases, and l

275 iculum (ER) stress as a mediator of impaired lipid metabolism, thereby contributing to fatty liver di

276 ide insight into the effects of dysregulated lipid metabolism they require a preexisting understandin

277 HCV infection perturbs host lipid metabolism through both cellular and virus-induced

278 ovel role for IL-19 in regulating macrophage lipid metabolism through peroxisome proliferator-activat

279 in the LHA kappaOR directly controls hepatic lipid metabolism through the parasympathetic nervous sys

280 and revealed a cluster of genes involved in lipid metabolism to be associated with the disease-resis

281 inately inhibit autophagy and reprogram host lipid metabolism to enable intracellular survival and pe

282 agy.IMPORTANCE Dengue virus alters host cell lipid metabolism to promote its infection.

283 ain elusive and the contribution of aberrant lipid metabolism to the malignant phenotypes of breast c

284 was significantly associated with fatty acid/lipid metabolism via PPAR signalling pathway.

285 Lipid metabolism was activated early (2 hours) in both B

286 Fasting and postprandial (HFMM) lipid metabolism was assessed by using indirect calorime

287 of key enzymes involved in carbohydrate and lipid metabolism was concomitantly changed.

288 xidative phosphorylation and perturbation of lipid metabolism was found in the distal SN that was not

289 The lipid metabolism was further dysregulated with increased

290 dipocytes, a cell type with highly regulated lipid metabolism, we generated mice with an adipocyte-sp

291 to its inhibition of SREBP and its effect on lipid metabolism, we show that Fatostatin's anticancer p

292 protein expression of the genes involved in lipid metabolism were analyzed.

293 The peripheral effects on lipid metabolism were assessed by histological technique

294 hondrial function, autophagy, ER stress, and lipid metabolism were measured in pancreatic tissue, aci

295 Genes implicated in fatty acid synthesis and lipid metabolism were significantly upregulated in the f

296 agy, beta-cell development and function, and lipid metabolism) were hypermethylated in placenta and c

297 erstanding how insulin regulates glucose and lipid metabolism, whereas the effect of insulin on prote

298 observe a commensurate functional defect in lipid metabolism whereby C3KO muscles fail to release fa

299 ein profiles except for proteins involved in lipid metabolism, which are present exclusively in the a

300 n to be activated in colon cancer, including lipid metabolism (z score 4.47), Notch signaling (4.47),