ライフサイエンスコーパス: lipidic

1 ional change is primarily dependent upon the lipidic aldehyde studied, not the protein sequence.

2 densation of lipidic isocyanides either with lipidic amines and oligosaccharidic acids or with fatty

3 roved efficient in the ligation to peptidic, lipidic and fluorescently labeled amines and in macrocyc

4 Cisternae appear to contain considerable lipidic and other material and to contain a substantial

5 dismutase, catalase, glutathione peroxidase, lipidic and protein peroxidation).

6 Thus, complexes formed in the presence of a lipidic antagonist to fusion are incompletely assembled,

7 ore with less stressed membrane, and becomes lipidic as it dilates, bending membrane into a highly cu

8 e the bending rigidity and tilt modulus, for lipidic assemblies of arbitrary lipid composition and sh

9 lowing to quantify the elastic properties of lipidic assemblies of arbitrary shape and composition (i

10 Our results suggest a model for the lipidic Bak pore, whereby the mitochondrial targeting C-

11 e amine oxide detergent micelles, whereas in lipidic bicelles a higher population of dimeric and high

12 treatment was seen to cause the inclusion of lipidic bodies into the nucleus.

13 us, and in the number, size, and location of lipidic bodies.

14 mulatory compounds were neither peptidic nor lipidic but instead were composed of sulfur and aromatic

15 inuity between the two adherent membranes is lipidic, but not aqueous.

16 The lipidic chlorophyll a and beta-carotene (beta-car) in cy

17 was a significant (P<0.001) reduction in the lipidic component of plaques in the regression group, an

18 ution MRI accurately quantifies fibrotic and lipidic components of atherosclerosis in this model.

19 trol fluidity homeostasis, we quantified the lipidic composition of insect SF9 and mammalian HEK 293T

20 usefulness of this technique to analyse the lipidic composition of margarine in a quick and easy way

21 ve and their open probability depends on the lipidic composition of the membrane in which they reside

22 ave studied the kinetics of establishing the lipidic connection between hemagglutinin-expressing cell

23 ral fusion proteins apparently involve local lipidic connections that evolve into a bilayer septum in

24 Knowledge of the lipidic contribution will hopefully inspire development

25 ration of the tryptophan side chain into the lipidic core stabilizes the membrane-bound conformation.

26 mbrane proteins uses a spontaneously forming lipidic cubic mesophase.

27 hough reconstitution of membrane proteins in lipidic cubic mesophases plays a prominent role in membr

28 omes, reconstitution of membrane proteins in lipidic cubic mesophases presents significant challenges

29 alyzing the beta2AR unfolding temperature in lipidic cubic phase (LCP) as a function of cholesterol c

30 The application of lipidic cubic phase (LCP) bilayer media for crystallizat

31 Lipidic cubic phase (LCP) crystallization has proven suc

32 We used GPCR engineering and lipidic cubic phase (LCP) crystallization to determine t

33 receptor (GPCR) family have established the lipidic cubic phase (LCP) environment as the medium of c

34 serial femtosecond crystallography (SFX) in lipidic cubic phase (LCP) for protein structure determin

35 Lipidic cubic phase (LCP) provides a suitable stabilizin

36 ZM241385 has previously been crystallized in lipidic cubic phase (LCP), structural differences in the

37 for membrane protein crystallization uses a lipidic cubic phase as the hosting medium.

38 ing local rearrangement of the highly curved lipidic cubic phase into a lamellar structure, which is

39 Crystals obtained in the lipidic cubic phase reveal the binding site of an endoge

40 Here we present a lipidic cubic phase SFX structure of the light-driven pr

41 nism, we have examined the properties of the lipidic cubic phase system and the dynamics of the GPCR

42 and soluble additives into the bicontinuous lipidic cubic phase under excess hydration are summarize

43 ork is the first incorporation of NKA into a lipidic cubic phase with consequent enzyme functionality

44 rotein crystallogenesis and transport in the lipidic cubic phase, the nature of the interaction betwe

45 h quality membrane protein crystals from the lipidic cubic phase.

46 grown in a membrane mimetic matrix known as lipidic cubic phase.

47 ns, they would assemble to form bicontinuous lipidic cubic phases (LCPs) that exhibit the well-known

48 ept of membrane protein crystallization from lipidic cubic phases, "in cubo", has yielded well-ordere

49 Because of the plasticity of lipidic cubic phases, it is envisaged that when mixed wi

50 teins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallogra

51 rial surfaces of land plants are coated by a lipidic cuticle, which forms a barrier against transpira

52 d compromised starvation survival and formed lipidic cysts instead of tumors, suggesting defective ut

53 et of lipid bilayers to bury its hydrophobic lipidic domain, leaving the hydrophilic polysaccharide c

54 ll biosynthesis by exporting fatty acids and lipidic elements of the cell wall.

55 with a positively stained core enclosed in a lipidic envelope with a mean diameter of 74 +/- 14 nm.

56 ous studies demonstrating a requirement of a lipidic environment for optimal activity with this enzym

57 ed proteins can elucidate how changes in the lipidic environment modulate membrane protein stability.

58 bility limitations of phenolic acids in many lipidic environments are now greatly improved by their e

59 ences for different PA species in particular lipidic environments were compared.

60 apoptotic BNIP3 protein dimerizes tightly in lipidic environments, and that this association has a st

61 may have an important role to tune ionic and lipidic flows through the pulmonary surfactant membrane

62 fferent chemical compounds produced from the lipidic fraction of different foodstuffs.

63 onance ((1)H NMR) has been used to study the lipidic fraction of margarines of different compositions

64 Rather, these results support the model of a lipidic fusion pore developing within a hemifused contac

65 essary for successful fusion, during which a lipidic fusion pore develops in a local and transient he

66 his suggests that fusion is completed when a lipidic fusion pore with net positive curvature is forme

67 exes likely contribute part of a protein and lipidic fusion pore.

68 We have developed a lipidic gene transfer vector, LPDII, where DNA was first

69 ion of fusion proteins in the context of the lipidic hypothesis of fusion.

70 ing that the pores are narrow and not purely lipidic in structure.

71 ance varies widely, another model proposes a lipidic initial pore.

72 bilayers through two semistable, nonlamellar lipidic intermediate states to a fusion pore.

73 ined by means of Ugi reactions incorporating lipidic isocyanides as surrogates of sphingolipids.

74 of glycolipid frameworks by condensation of lipidic isocyanides either with lipidic amines and oligo

75 on of aliphatic, dipeptidic, glucosidic, and lipidic isocyanides with several amino acids, thus givin

76 : a rupture-insertion pathway leading to the lipidic junction and a hemifusion-stalk pathway leading

77 on diaphragm and a novel structure termed a 'lipidic junction'.

78 Liposomes with lipidic junctions were ruptured with membrane edges stab

79 The lipidic liquid-crystalline cubic phase (LCP) is a membra

80 n MRI and histopathology for the analysis of lipidic (low signal on T2W, r = 0.81) and fibrous (high

81 show that its correct reconstitution in the lipidic matrix can be used to generate macroscopic proto

82 In vitro, the lipidic mediator resolvin D1 (RvD1) down regulated the M

83 The lipidic mediator RvD1, which stimulates Abeta phagocytos

84 The effect of incorporating the lipidic medium-chain triglyceride (MCT) into polymeric f

85 rotein translocation across membranes with a lipidic membrane pore being a transient translocation in

86 e, which in turn triggers the formation of a lipidic membrane pore with a putative toroidal structure

87 ch rapidly and stably integrates cargos into lipidic membranes of nanocarriers after simple mixing th

88 ein in lipid bilayers through the use of the lipidic mesophase method, and determined its structure a

89 tions of membrane protein crystallization in lipidic mesophases and for studies of the suitability of

90 ions for the mechanism of crystallization in lipidic mesophases as discussed.

91 d selective membrane protein transporters in lipidic mesophases, exemplified by the bacterial ClC exc

92 he crystallization of membrane proteins from lipidic mesophases.

93 the crystallization of membrane proteins in lipidic mesophases.

94 for crystallogenesis of membrane proteins in lipidic mesophases.

95 peptide synthetases (NRPSs) produce complex lipidic metabolites by using a thio-template mechanism o

96 hat an insect endosymbiont acquires specific lipidic metabolites from the transport lipoproteins in t

97 se results show that a family of chlorinated lipidic metabolites is produced from alpha-chloro fatty

98 n using LC-QTOF-MS and GC-Q-MS for polar and lipidic metabolites.

99 cells, LXR agonists reduced SR-B1-dependent lipidic-micelle-induced Erk phosphorylation.

100 o) by mechanisms that may involve endogenous lipidic modulators.

101 Compound 3, which bore a lipidic moiety in a branched tetramer structure, showed

102 A lipidic N,N'-dimethylethylenediamine derivative (4) cont

103 trate in vivo a postformulation strategy for lipidic nanocarrier functionalization with the use of a

104 ation to achieve multiplexing capability for lipidic nanocarriers.

105 on, the stalk or rhombohedral phase exhibits lipidic passages (stalks) between adjacent bilayers, rep

106 ide, designated mycoketide, which contains a lipidic pathogen-associated molecular pattern.

107 aluable insights into asthma mechanisms once lipidic peroxidation assessed by urinary metabolomics is

108 ish, membrane adhesion and fusion on a novel lipidic platform suitable for imaging by fluorescence mi

109 ay important role in the sealing function of lipidic polymers in planta.

110 n sum, we propose that activated Bax induces lipidic pore formation and that MOM proteins assist clea

111 t are at least partially composed of lipids (lipidic pore formation).

112 Corresponding to a physical theory for lipidic pore formation, Bax potently diminished the line

113 Using a theory for lipidic pore formation, we analyzed these data to quanti

114 ince the membrane monolayer must bend during lipidic pore formation, we here explore the effect of in

115 s developed that describes the dynamics of a lipidic pore in a liposome.

116 The edge tension of a lipidic pore is calculated by using the theory to quanti

117 osis, enabling the proposal of a BAK-induced lipidic pore with the topography of a "worm hole."

118 ent with a decrease in the line tension of a lipidic pore.

119 lity data are inconsistent with formation of lipidic pores capable of transporting megadalton-sized m

120 Evidence suggests that the formation of such lipidic pores is a major mechanism for alpha-pore-formin

121 dimers form disordered clusters to generate lipidic pores.

122 s with diameters of 25-100 nm, suggestive of lipidic pores.

123 oil rich in docosahexaenoic acid (DHA-OR) on lipidic postprandial oxidative stress in Wistar rats.

124 de level and antioxidant status related to a lipidic postprandial state.

125 The deleterious effects of ammonium-based lipidic salts on cellular processes have been well-estab

126 ted into membranes at SecYEG or from SecA at lipidic sites.

127 ing to a reduction in the energy of a purely lipidic stalk by several tens of k(B)T.

128 To determine the lipidic structure of the pore, the pores in peptide-lipi

129 to the production of the various contrasting lipidic structures that are assembled together to give r

130 at the protein epsin 1 induces highly curved lipidic structures when added with clathrin to appropria

131 The structures show cavities for both lipidic substrates, which converge at the active site.

132 nnector indicates a defined interaction with lipidic surfaces, suggesting that, when bound to larger

133 routines to align MD trajectories of complex lipidic systems, to determine the water/lipid interface,

134 , wherein two of the components provided the lipidic tails while a third one incorporated either the

135 A panel of lipidic tetraalkylammonium chlorides has been prepared a

136 The lipidic vesicle envelope is apparently a functional anal

137 A domain and several chimeric variants with lipidic vesicles was examined here by isothermal titrati